Infection and Immunity Seminar: Mads Gyrd-Hansen: Ubiquitin signalling in inflammation: towards identifying new therapeutic targets

07.04.2017 | Lisbeth Heilesen

Dato ons 19 apr
Tid 14:00 15:00
Sted Merete Barker Auditorium (Lakeside Lecture Theatre)

Professor Mads Gyrd-Hansen, University of Oxford Time: April 19, kl 14 15 Venue: Merete Barker (Lake side auditorium). Title:” Ubiquitin signalling in inflammation: towards identifying new therapeutic targets” Ubiquitin is used as a central switch in cellular signaling, and is important for a range of processes, including control of cancer development, as well as in the immune system. Mads Gyrd-Hansen is interested in understanding the role and regulation of ubiquitin modifications that control signalling during inflammatory processes. The medical importance of this biological area is emphasized by the recent identification of both inflammatory diseases and immunodeficiencies in individuals with dysregulation of the ubiquitin system. In the talk, Mads will give an overview of both the basics and the latest developments in ubiquitin biology, and will show recent data from his very active research program. Select publications by Mads Gyrd-Hansen: Mol Cell. 2016 Sep 15;63(6):990-1005 Mol Cell. 2014 May 8;54(3):335-48 EMBO Mol Med. 2013 Aug;5(8):1278-95. Mol Cell. 2013 Jun 27;50(6):818-30. Mol Cell. 2012 Jun 29;46(6):746-58. Nat Rev Cancer. 2010 Aug;10(8):561-74. Nat Cell Biol. 2008 Nov;10(11):1309-17. All are welcome, Regards Rune and Soren Rune Hartmann PhD, associate Professor Center for Structural Biology Dept. of Molecular Biology and Genetics; Aarhus University. Gustav Wieds Vej 10c, DK-8000 Aarhus C, Denmark

Professor Mads Gyrd-Hansen, University of Oxford

Time: April 19, kl 14 15

Venue: Merete Barker (Lake side auditorium).

Title:” Ubiquitin signalling in inflammation: towards identifying new therapeutic targets

 

Ubiquitin is used as a central switch in cellular signaling, and is important for a range of processes, including control of cancer development, as well as in the immune system. Mads Gyrd-Hansen is interested in understanding the role and regulation of ubiquitin modifications that control signalling during inflammatory processes. The medical importance of this biological area is emphasized by the recent identification of both inflammatory diseases and immunodeficiencies in individuals with dysregulation of the ubiquitin system. In the talk, Mads will give an overview of both the basics and the latest developments in ubiquitin biology, and will show recent data from his very active research program.

 

Select publications by Mads Gyrd-Hansen:

Mol Cell. 2016 Sep 15;63(6):990-1005

Mol Cell. 2014 May 8;54(3):335-48

EMBO Mol Med. 2013 Aug;5(8):1278-95.

Mol Cell. 2013 Jun 27;50(6):818-30.

Mol Cell. 2012 Jun 29;46(6):746-58.

Nat Rev Cancer. 2010 Aug;10(8):561-74.

Nat Cell Biol. 2008 Nov;10(11):1309-17.

 

All are welcome,

 

Regards

Rune and Soren

 

 

 

 

Rune Hartmann

PhD, associate Professor

 

Center for Structural Biology

Dept. of Molecular Biology and Genetics; Aarhus University.

Gustav Wieds Vej 10c, DK-8000 Aarhus C, Denmark

Arrangement