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Researchers reveal how bacteria can adapt to resist treatment by antibiotics



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Poul Nissen (photo: Lisbeth Heilesen/AU)

2019.04.25 | Grant

Poul Nissen receives EUR 1.34 million to study the insulin receptor

The Novo Nordisk Foundation has awarded Professor Poul Nissen a five-year grant in the form of a so-called "NNF Distinguished Investigator 2019 grant" within "Bioscience and Basic Biomedicine", which is given to researchers who have shown their ability to carry out and lead research at the very highest international level.

The figure shows how the enzyme PpnN binds pppGpp and speeds up conversion of guanylate (GMP) to its constituents ribose-5-phosphate and guanine. This enables bacteria to balance their tolerance towards antibiotics with the fitness requirements for survival (below). Ditlev E. Brodersen/AU

2019.04.23 | Research

Researchers reveal how bacteria can adapt to resist treatment by antibiotics

In a joint collaboration, researchers from Denmark and Switzerland have shown that bacteria produce a specific stress molecule, divide more slowly, and thus save energy when they are exposed to antibiotics. The new knowledge is expected to form the basis for development of a new type of antibiotics.

Structure of the calciumpump highlighting where the minor (blue spheres) and major (red spheres) differences between calciumpumps are located in the structure. With this knowledge it is possible to target specific pumps.

2019.04.11 | Research

New insights into calcium transport may help develop new drugs

A normal function of the heart and nerve system is, among other things, dependent on proper regulation of calcium in the cells. This process depends on the proper functioning of the calcium pump. New studies of the calcium pump structure give new insight into this process, which may help with the development of new drugs for treatment such as…

Dr. Hossein Mohammad-Beigi and Professor Daniel Otzen, Aarhus University, shows that a specific and widely common strain of olives excels as a natural inhibitor of Parkinson’s disease progress. (Image: Colourbox.com)

2019.04.01 | Research

Widely common olive species excel as natural inhibitor of Parkinson’s disease

The compositions of antioxidants in a certain species of olive fruits have been found to be superior in protection against Parkinson's disease. As Parkinson's disease is one of the most common neurodegenerative diseases, but still without a cure, this is an important finding on the way to combat this crippling condition.

Events

Mon 27 May
14:15-16:00 | AIAS Auditorium, Building 1632
AIAS Fellows' Seminar: Tomonori Takeuchi: Memory modulation by light
Tue 28 May
14:00-15:00 | The Merete Barker Auditorium, The lakeside lecture theatres
Infection & Inflammation seminar: Nelson Gekara: Cross-talks between the DNA damage response and Innate Immunity
Tue 04 Jun
13:00-16:00 | The lecture theater building 1231, room 424
Open Space / Biobank Seminar

PhD defences

Juliane Martin

2019.04.26 | PhD defense

Juliane Martin: Foraging Decisions in Mice under Uncertainty

PhD defence, Friday 26 April 2019. Juliane Martin.

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