During his Phd-studies, Claus Tofting-Olesen investigated the non-ribosomal peptide synthetases (NRPSs). NRPSs are among the world biggest enzymes and are responsible for the production of very complex molecules, many of which are considered to be among the most important pharmaceuticals known. The mechanisms behind the production of these valuable drugs are not fully understood and the aim of this research was to obtain a better understanding of how the NRPSs function. Claus Tofting-Olesen focused on NRPSs found in the genus Fusarium

The PhD degree was completed at Department of Molecular Biology and Genetics, Science and Technology, Aarhus University, Denmark

This résumé was prepared by the PhD student.

Time: Tuesday 19 April 2016 at 13:00
Place: Building 1324, room 011, Tvillingeauditorierne, Bartholins Allé 10, 8000 Aarhus C.
Title of dissertation: Structural Studies of Fungal Nonribosomal Peptide Synthetases
Contact information: Claus Tofting-Olesen, e-mail: Clausol@mbg.au.dk, tel.:+45 61273042

Members of the assessment committee:
Professor Sean Doyle, Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland
Professor Michael Overgaard, The Faculty of Engineering and Science, Department of Chemistry and Bioscience, Section of Biotechnology, Aalborg University, Denmark
Professor Claus Oxvig (chair), Department of Molecular Biology and Genetics, Aarhus University, Denmark
Main supervisor:
Associate professor, Ditlev E. Brodersen, Department of Molecular Biology and Genetics, Aarhus University, Denmark
Language: The PhD dissertation will be defended in English

The defence is public.
The dissertation is available for reading at the Graduate School of Science and Technology/GSST, Ny Munkegade 120, building 1520, rooms 128-134, 8000 Aarhus C.