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Rasmus Peter Thomsen: Use of DNA nanotechnology to control molecular systems

PhD defense, Wednesday, 14 November 2018. Rasmus Peter Thomsen.

2018.11.14 | Lisbeth Heilesen

Rasmus Peter Thomsen

Examples of two DNA nanostructures used to engineer lipid bilayers and proteins, respectively.

The ability to engineer, control, and manipulate molecular assemblies is emerging and one approach to do so involves the use of DNA nanostructures and designs. This approach has evolved immensely since its inception more than 35 years ago. During his PhD studies, Rasmus Peter Thomsen has designed, developed, and used DNA nanotechnology to engineer peptides, proteins, and lipid membranes. Common to all projects are the use of DNA as a structural scaffold, modified chemically and enzymatically with functional probes. The systems have been uniquely designed towards a desired purpose. Put together, the results demonstrate the versatility and modularity of DNA nanotechnology, which can serve as a nanoscale engineering tool by providing a programmable scaffold.

The PhD degree was completed at the Interdisciplinary Nanoscience Center (iNANO), Science and Technology, Aarhus University.

This résumé was prepared by the PhD student. 

Time: Wednesday, 14 November 2018 at 13.15
Place: Building 1593, room 012, the Lecture Theatre, iNANO House, Gustav Wieds Vej 14, Aarhus University, 8000 Aarhus C.
Title of PhD thesis: Engineering Peptides, Proteins, and Lipid Membranes with DNA Nanotechnology
Contact information: Rasmus Peter Thomsen, e-mail: thomsen3@inano.au.dk, tel.: +45 2543 0262
Members of the assessment committee:
Professor Hendrik Dietz, Department of Physics, Technical University Munich, Germany
Professor Dimitrios Stamou, Bio-nanotechnology and Nanomedicine Group, Department of Chemistry, Faculty of Science, University of Copenhagen
Professor Jan Skov Pedersen (chair), iNANO and Department of Chemistry, Aarhus University

Main supervisor:
Professor Jørgen Kjems, iNANO and Department of Molecular Biology and Genetics, Aarhus University
Professor Jesper Wengel, Department of Physics, Chemistry and Pharmacy, University of  Southern Denmark
Language: The PhD dissertation will be defended in English

The defense is public.
The PhD thesis is available for reading at the Graduate School of Science and Technology/GSST, Ny Munkegade 120, building 1520 and 1521, 8000 Aarhus C.

PhD defense