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Seminar: Thorsten Nürnberger: Patterns and receptors in plant immunity to microbial infection

2017.01.03 | Lisbeth Heilesen

Date Mon 09 Jan
Time 10:00 11:00
Location Meeting room 2, AU Conference Centre, Fredrik Nielsens Vej 4. (Bygning 1421)

Thorsten Nuernberger:

 

Patterns and receptors in plant immunity to microbial infection

 

Host pattern recognition receptor-mediated perception of microbe-associated molecular patterns (MAMP) is a prerequisite for the initiation of antimicrobial defenses in all multicellular organisms including plants. We report on the rapid identification of two novel pattern recognition receptors (RLP23, RLP32) by exploiting the natural variation of PRRs within Arabidopsis ecotypes. Both receptors belong to the class of leucine rich-repeat (LRR) proteins lacking a cytoplasmic kinase domain, interact constitutively with and require SOBIR1 as a co-receptor, and recruit into the RLP/SOBIR1 complex another co-receptor, BAK1, in an ligand-dependent manner. Stable expression of RLP23 in tomato or potato conferred enhanced immunity to microbial infection, suggesting that interfamily transfer of plant pattern recognition receptors (PRRs) constitutes a generally applicable strategy for engineering durable immunity in crop plants. Further, a microbial toxin receptor in plants through which a common microbial effector class exerts its virulence function during host infection will be presented.

Host: Jens Stougaard

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