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Professor Gregers Rom Andersen (photo: Lisbeth Heilesen)

2013.01.24 | Public / media, Department of Molecular Biology and Genetics

New professor with focus on the immune system

Gregers Rom Andersen has been appointed professor of structural biology at the Department of Molecular Biology and Genetics at Aarhus University

The Spotted Landrace pig is one of the old farm animal breeds that is worth preserving. Photo: Colourbox

2013.01.21 | Public / media, Department of Molecular Biology and Genetics

The history of Danish historic animals

A new report describes the work on preserving the genetic resources of Danish livestock.

Maria Andreasen (photo: Lisbeth Heilesen)

2013.01.15 | Public / media, Department of Molecular Biology and Genetics

Young elite researcher prize awarded to Maria Andreasen

The Danish Council for Independent Research | Natural Sciences (FNU) has awarded Maria Andreasen a prestigious Sapere Aude Young Elite Researcher Prize for her research project entitled: “Caught in the act – Identifying primary nucleation events for fibrillating proteins.”

Eva Arnspang Christensen has been granted DKK 2.245 million from the Sapere Aude programme to learn advanced microscopy techniques at the National Institutes of Health, USA (photo: Lisbeth Heilesen)

2013.01.11 | Public / media, Department of Molecular Biology and Genetics

Young Elite Researcher Prize awarded to Eva Arnspang Christensen

The Danish Council for Independent Research | Natural Sciences (FNU) has awarded a prestigious Sapere Aude Young Elite Researcher Prize valued at DKK 2.245 million to Postdoctoral Fellow Eva Arnspang Christensen (36), Department of Molecular Biology and Genetics, for her research project ‘Aquaporin assembly and regulation: studied by…

A new booklet from the Danish Museum of Natural History is filled with lots of interesting information about poultry. Photo: Janne Hansen

2013.01.11 | Public / media, Department of Molecular Biology and Genetics

Booklet on the hen

A new booklet published by the Danish Museum of Natural History, written by senior scientist Poul Sørensen from Aarhus University, covers the subject of hens and chickens in an easily approachable way.

The researchers behind the study, from left: Jacob Fredsøe, Anni Hangaard Andersen and Jakob Madsen Pedersen (photo: Lisbeth Heilesen) Click photo and figures for enlargement.
Topoisomerases are required for transcription of chromatin regulated genes. Transcription levels of the individual genes are measured by qPCR in cells with (wild type) or without (top1?top2ts) topoisomerases. (figure: Jacob Fredsøe)
Topoisomerases are required for binding of transcription factor Pho4 to the promoter region of the chromatin regulated PHO5 gene and thereby for activation of this gene. The four nucleosomes in the PHO5 promoter (A) remain bound to the PHO5 promoter in the absence of topoisomerases (B). Under normal conditions the Pho4 transcription factor binds UAS1 after which chromatin remodelers are recruited to remove nucleosomes and allow further binding of transcription factors. In the absence of topoisomerases the Pho4 transcription factor still enters the nucleus (C), but is unable to bind the PHO5 promoter (D). (figure: Jacob Fredsøe)

2013.01.03 | Public / media, Department of Molecular Biology and Genetics

DNA topology important for gene activity

Maintenance of all life requires a strict control of gene activity for the cell to give an optimal response to internal as well as environmental changes. New results now demonstrate that DNA topology plays an important role.