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Results show that there is basis for improving the selection criteria for reproductive performande in dairy cows. Photo: Linda S. Sørensen

2016.05.29 | Research

Improved breeding value assessment for reproductive performance in dairy cows

The routine breeding value assessment for reproductive performance in Denmark and Sweden may be improved by means of activity-based fertility traits. This is demonstrated by results from a recently finished PhD project. In addition, it has been demonstrated that the genetic variation in reproductive performance changes in relation to calving…

The bacterial transporter whose molecular structure has been solved uses the same transport mechanism as the neurotransmitter transporters but instead transports amino acids, such as leucine (Leu). In the outward-oriented state (left) Leu (yellow spheres) binds to two sodium ions (green spheres) in a central binding pocket whereas the rotating unit, designated L25 (beige spheres), is located next to the binding pocket of the  transported substance. In the new empty state (right) which the Aarhus researchers have now identified, L25 rotates into the binding pocket where it mimics and compensates for the lacking substance and sodium ions, enabling the transporter to return to an outward-oriented state from which it can start a new transport cycle.  Figure: Lina Malinauskaite.

2016.05.26 | Research

New discovery from the molecular machinery for depression and addiction

Researchers at Aarhus University have described how a group of the brain’s transport proteins with important roles in depression and dependence overcome the step which limits their effectiveness. The discovery makes it possible to describe the full function of the transport protein and can provide better opportunities for counteracting the effect…

Mogens Duch

2016.05.23 | People

Obituary for Senior Researcher Mogens Duch (1958-2016)

Mogens Duch, senior researcher at the Department of Molecular Biology and Genetics, died suddenly on Friday 20 May 2016, aged 58.

Schematic represention of agotron biogenesis and function. Agotrons are derived from short introns produced during RNA splicing. Upon association with Ago proteins, agotrons target and destabilize mRNAs in a miRNA like manner. Figure: Thomas Birkballe Hansen.

2016.05.18 | Research

Agotrons – a new class of small regulatory molecules

Danish and American researchers have found a novel subclass of small RNA molecules involved in the regulation of gene expression.

Researchers from Aarhus University participate in a new national project to ensure that protein researchers will have access to the latest advanced equipment. The goal is to maintain Denmark’s leading position in protein research and to strengthen infrastructure and technological development. Photo: Colourbox

2016.05.13 | Grant, Knowledge exchange

40 million Danish kroner for protein research

Researchers from Aarhus University participate in a new national project to ensure that protein researchers will have access to the latest advanced equipment. The goal is to maintain Denmark’s leading position in protein research and to strengthen infrastructure and technological development.

Jørgen Kjems was awarded DKK 6.1 million to develop a new method that can "translate" the total content of food to digitized information in the form of DNA sequences. Photo: Lars Kruse, AU Foto.

2016.05.12 | Grant

Jørgen Kjems awarded Semper Ardens grant from the Carlsberg Foundation

The Carlsberg Foundation has awarded Jørgen Kjems DKK 6.1 million to develop a new method that can "translate" the total content in a specific food to digitized information in the form of DNA sequences.

Schematic drawing of the active site of the calcium pump that completes the ATP cleavage reaction. The outline of this region of the protein (which is a long chain of 994 amino acid residues and approximately 15,000 atoms in total) is shown as white and yellow features and includes detailed representations of two catalytically important amino acid residues as red and white sticks (oxygen and carbon atoms). The red spheres represent bound water molecules, and the magenta sphere a magnesium ion that coordinates the phosphorylated amino acid side chain (an aspartic acid, lower) and the vanadate mimic of the phosphate “caught in the act” of cleavage (middle) by a water molecule positioned on top. The water is activated for the reaction by another catalytically active amino acid side chain (a glutamatic acid). This active site architecture is nearly identical in all ion pumps and responsible for approximately 1/3 of the ATP energy consumption in the human body. (Figure: Dr. Johannes Clausen).

2016.05.09 | Research

A calcium pump caught in the act

Researchers at Aarhus University have described one of the cell’s key enzymes, the calcium pump, in its decisive moment – a so-called transition state where a catalyzed activity makes the turning point from bound substrate to product. These findings provide a very detailed picture of how one of the most energy-consuming processes in the body takes…

At a ceremony at the Novo Nordisk Foundation, Malene Runge Jepsen received a postdoctoral grant to carry out research at Monash University in Australia for three years, followed by a one-year research period at MBG. Malene is seen in the middle with a striped blouse (Photo: Novo Nordisk Foundation).
Malene Runge Jepsen (Photo: Novo Nordisk Foundation)

2016.05.02 | Grant

Young researcher receives major grant to conduct research at Australian university

At a ceremony at the Novo Nordisk Foundation, Malene Runge Jepsen from the Department of Molecular Biology and Genetics (MBG) received a postdoctoral grant to carry out research at Monash University in Australia for three years, followed by a one-year research period at MBG.