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News

Measuring methane emissions from cows is the essence of a newly started research network which has received 4 million DKK for the next four years. Postdoc Jan Lassen from the Department of Molecular Biology and Genetics at Aarhus University will be co-heading the network together with a Dutch colleague. Photo: Søren Tobberup Hansen, AU

2013.05.28 | Public / media, Department of Molecular Biology and Genetics

New European science network on methane challenges and genetics in ruminants

A new EU-supported network that aims, among other things, to improve measurements of methane emissions from ruminants is co-chaired by a scientist from Aarhus University.

On 13 and 14 June the strategic research centre GenSAP, which has its home at research centre AU Foulum, will be officially inaugurated with an opening symposium held at Aarhus and Foulum. Photo: Colourbox

2013.05.17 | Public / media, Department of Molecular Biology and Genetics

Revolutionising science centre opens at MBG Foulum

The strategic research centre GenSAP, which aim to develop new genomic selection tools for animal and plant breeding, will be officially opened with a two-day opening symposium in June.

Fig. 1. Fibril formation. A: Thioflavin T (ThT) fluorescence analysis of amyloid formation. B-G: AFM pictures of amyloid formation hIAPP20-29. B: 0h, only tiny oligomers that are approximately 1.4 nm tall are visible. C: 1h, unorganised structures are visible. The striped box is highlighted in order to get a more detailed picture of the structure. D: 1.5h, the structure is more organised and is still growing wider. E-G: 2h, 5h, and 24h, the string begins to twist and grow, cf. transforms into fibrils, however, some of the strings do not transform (highlighted by striped arrows). H: the different structures’ height at different points in time, and the average height for the enterer experiment.

2013.05.08 | Public / media, Department of Molecular Biology and Genetics

Scientists map type 2 diabetes’ stages of evolution

Many neurodegenerative diseases, e.g. Parkinson, Alzheimer, and Huntington, are caused by the formation of fibrils that is developed from tiny twisted proteins. As a rule one specific protein is connected to one specific disease. However, new research suggests that the formation of fibrils can be associated with other diseases, e.g. type 2…

Researchers from many different countries met at Aarhus University to share their experience with neutron protein crystallography. Photo: Poul Nissen
Monika Budayova-Spano from Grenoble, France, is shown addressing the symposium audience about her experience and results. Photo: Ditlev Brodersen

2013.04.05 | Public / media, Department of Molecular Biology and Genetics

Molecular Biology and Genetics researchers focus attention on billion investment in research

The best and most powerful neutron source in the world – The European Spallation Source (ESS) – will open in Lund, Sweden, in 2019. Denmark is contributing with more than DKK 1 billion to the construction of the new facility. How will basic research in structural biology, biotechnology and medicinal chemistry get the most out of this investment? A…

Torben Heick Jensen has been invited to give a seminar in the prestigious ‘Mendel Lecture series’ in Brno, the Czech Republic. Photo: Lisbeth Heilesen

2013.04.05 | Public / media, Department of Molecular Biology and Genetics

Torben Heick Jensen speaker at highly esteemed lecture series

Torben Heick Jensen - Professor at the Department of Molecular Biology and Genetics and Director of the Danish National Research Foundation-funded centre for mRNP Biogenesis and Metabolism - has been invited to give a talk in the prestigious ‘Mendel Lecture series’. The event is taking place on 18th April 2013 in Brno, the Czech Republic.

Scientists from Aarhus University have discovered why some species of cereal have higher phytase activity than others and have patented a method for increasing phytase activity in cereal. Photo: Janne Hansen

2013.04.02 | Public / media, Department of Molecular Biology and Genetics

Phosphorus in wheat can be made more readily available

Scientists from Aarhus University have discovered why some species of cereal have higher phytase activity than others and have patented a method for increasing phytase activity in cereal.

Professor Jens Stougaard is part of an international research team that is involved in developing maize that can create its own fertiliser. On a global scale, this could lead to a reduction in the use of artificial fertilisers and thereby less environmental pollution. Photo: Lisbeth Heilesen
The researchers will now try to get maize to establish symbiosis with bacteria  that can use atmospheric nitrogen, so the plant creates its own fertiliser. Photo: Balaram Mahalder
Dr Stougaard’s research group has already found out how legumes are able to establish symbiosis with bacteria. This knowledge will now be transferred to maize and other cereal crops, so farmers can benefit from this knowledge. Here is the legume Japanese birdsfoot (Lotus japonicus) with nitrogen-fixing root nodules. Photo: Centre for Carbohydrate Recognition and Signalling

2013.03.21 | Public / media, Department of Molecular Biology and Genetics

Super maize can put sustainable food on the table

A new research project financed by the Bill & Melinda Gates Foundation should pave the way towards a cheap and sustainable solution to some of Africa’s food problems. Researchers at Aarhus University are involved in the efforts to develop maize that can create its own fertiliser. On a global scale, this could lead to a reduction in the use of…

Sodium-potassium pump with binding-pocket for cardiotonic steroids (light blue / red structure). The yellow areas indicate the position of the Na<sup>+</sup>, K<sup>+</sup>-ATPase in which mutations are known to affect the binding of the drug - notice how they clearly enclose the binding pocketFigure: Laure Yatime
The sodium-potassium pump (Na<sup>+</sup>, K<sup>+</sup>-ATPase). Figure: Laure Yatime
First author Laure Yatime carried out the most important part of the research that won the Paper of the Year Award, for which she received a cash prize and a certificate. Photo: Lisbeth Heilesen

2013.03.15 | Public / media, Department of Molecular Biology and Genetics

Award to the first step towards designing less toxic cardiovascular drugs

New results from Aarhus University show the first, crucial step in dissecting the molecular mechanism behind drugs with an important effect on the heart. The scientific article with these important results was nominated “Paper-of-the-Year” by the international Journal of Structural Biology.

The three researchers, who were given a centre grant, receive the diploma from Peter Olesen. From left to right: Chairman Peter Olesen, Professor Per Torp Sangild (KU), Professor Mogens Sandø Lund (AU) and Associate Professor Qingfeng Li (DTU). Photo:  The Danish Council for Strategic Research

2013.03.14 | Public / media, Department of Molecular Biology and Genetics

Mogens Sandø Lund awarded diploma from the Danish Council for Strategic Research

The chairman of the Danish Council for Strategic Research, Peter Olesen, awards diplomas to the three researchers who were given a grant by the council for a centre in 2012.

A genomic selection project aiming to achieve annual breeding improvements in pigs of 50 percent involves scientists from Aarhus University. Photo: AUed deltagelse af forskere fra Aarhus Universitet til at øge den årlige avlsfremgang med 50 procent. Foto: AU

2013.03.12 | Public / media, Department of Molecular Biology and Genetics

Slaughter pigs to be improved by genomic selection

Genomic selection has been successfully implemented in the breeding programme for sows. Now it is turn for slaughter pigs to undergo breeding improvements.

The calcium pump
The SERCA calcium pump is located in the sarcoplasmic reticulum membrane and pumps calcium ions (yellow) out of the cytoplasm in muscle cells. The sarcolipin molecule (turquoise) keeps the SERCA structure in place with the door open for calcium. This door is illustrated as a pink structure that moves up and down to open and close the door for the calcium ions’ transport pockets inside the protein.

2013.03.08 | Department of Molecular Biology and Genetics, Public / media

Last image in a molecular ‘comic strip’ now in place

Researchers at Aarhus University have worked together with a newly started biotech company to draw the last image in a scientific ‘comic strip’ that illustrates the migration and function of calcium in the body. Their discovery has been published in the journal Nature and has great significance for product development – particularly…

From the launch of DANDRITE, the Danish node in the EMBL Nordic Partnership in Molecular Medicine, and the signing of the Nordic EMBL agreement at Aarhus University: From left to right Director Poul Nissen, DANDRITE, Director General Iain Mattaj, EMBL, Rector Thomas Wilhelmsson, University of Helsinki, Rector Lena Gustafsson, Umeå University, Rector Ole Petter Ottersen, University of Oslo, the directors of the other nodes in the EMBL Nordic Partnership Olli Kallioniemi, (FIMM), Bernt Eric Uhlin (MIMS), Kjetil Taskén (NCMM), and Rector Lauritz B. Holm-Nielsen, Aarhus University. Photo: Lise Balsby/AU Kommunikation.

2013.03.06 | Public / media, Department of Molecular Biology and Genetics

Lundbeck Foundation Centre in Aarhus for top European brain research

The European Molecular Biology Laboratory (EMBL), Europe’s flagship laboratory for the life sciences, is now joining forces with Aarhus University as its Danish partner of the Nordic EMBL Partnership for Molecular Medicine. On the initiative of the Lundbeck Foundation, a new elite research centre – DANDRITE – is to form the prestigious setting for…

Illustration showing the circular molecule – ciRS-7 (circular RNA sponge for miR-7) – which has captured microRNAs and thereby inactivated them (figure: Reza M. Zadegan)
The expression of circular RNA CIRS-7 and miR-7 in the mouse brain. Panels a and c indicate the presence of the CIRS-7 visualised with a dark colour. When compared with the presence of miR-7 (panels b and d) a clear overlap is seen. Panel e shows the presence of CIRS-7 stained with a fluorescent probe, which indicates that this circular RNA is one of the most highly expressed RNAs in mouse brain neurons (figure: Thomas Birkballe Hansen and Bettina H. Clausen) - Click figures for enlargement

2013.02.28 | Department of Molecular Biology and Genetics, Public / media

New knowledge about the human genome

Danish researchers have discovered a completely new function in human cells. In the long term, this could be very significant for understanding and treating a considerable number of human diseases. The results have been described in the international journal Nature.

Computer-processed image of a nerve cell.

2013.02.28 | Department of Molecular Biology and Genetics, Public / media

Aarhus University celebrates elite partnership

The European Molecular Biology Laboratory (EMBL) – Europe’s flagship for basic research in the life sciences – is including Aarhus University as its Danish partner. This will be celebrated in the Main Hall on 5 March with the inauguration of the DANDRITE neuroscience centre, which will make Aarhus a magnet for top international research into…

The zebrafish is a popular aquarium fish. In common with human beings, the fish is a vertebrate and it is widely used in research as a model organism (photo: Wikimedia Commons)
In the absence of the protein PAPP-A, the development of zebrafish is severely delayed (photo: Kasper Kjær-Sørensen)
The early processes of embryonic development can be manipulated at the molecular level by injecting material into the fertilised egg using a thin glass needle (photo: Kasper Kjær-Sørensen)
Ditte Høyer Engholm in front of the research group’s aquaria with zebrafish (photo: Lars Kruse)

2013.02.22 | Public / media, Department of Molecular Biology and Genetics

From pregnant women to zebrafish

By using zebrafish as a model organism, Danish researchers have now found a novel function of PAPP-A, which regulates the earliest embryonic development. The protein PAPP-A is normally associated with pregnancy, where the concentration in the blood is reduced if the woman is carrying a child with Down’s syndrome. But even though the measurement of…

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