Foldning af RNA origami by a polymerase enzyme. A graphic representation of RNA nanostructures. Graphics: Cody Geary, AU.
Cody Geary (left) and Ebbe Sloth Andersen make origami from RNA helixes. Here they stand on the helix shaped stairway to their office at Aarhus Universitety. Photo: Peter F. Gammelby, AU.

2014.08.19 | Research

Scientists fold RNA origami from a single strand

RNA origami is a new method for organizing molecules on the nanoscale. Using just a single strand of RNA, many complicated shapes can be fabricated by this technique. Unlike existing methods for folding DNA molecules, RNA origamis are produced by enzymes and they simultaneously fold into pre-designed shapes. These features may allow designer RNA…

the function of the zinc pump when it forces zinc ions across the cell membrane. From left: Poul Nissen, Henriette Autzen, Oleg Sitsel, Tetyana Klymchuk, Pontus Gourdon, Anna Marie Nielsen and Kaituo Wang (Photo: Rasmus Rørbæk)

2014.08.18 | Research

Don’t zinc - do!

Aarhus University’s PUMPkin Centre – a Centre of Excellence funded by the Danish National Research Foundation – has just succeeded in ‘taking’ the first photos of the mechanism that transports zinc out of the cells of organisms such as bacteria and plants. The study has just been published in Nature.

Gregers Rom Andersen (left) and Janus Asbjørn Schatz-Jakobsen

2014.08.18 | Awards

Nomination of the teacher and student teacher of the year at MBG

Gregers Rom Andersen was nominated the teacher of the year and Janus Asbjørn Schatz-Jakobsen the student teacher of the year at the Annual Meeting of the Department of Molecular Biology and Genetics on Friday 15 August 2015.

More knowledge about how nitrogen compounds affect the plant can be useful in preventing fungal disease in barley. Photo: Janne Hansen

2014.08.13 | Grant

Nitrogen compounds control disease resistance in cereals

Nitrogen compounds play an important role in the plant’s fight against fungal diseases. Researchers are now seeking a better understanding of these mechanisms. This may present plant breeders with some new genetic tools for their work.

Professor Jens Stougaard laid the foundation for his numerous significant publications when he established the birdsfoot trefoil (<em>Lotus japonicus</em>) legume as a model organism, and large amounts are now cultivated in the research group’s greenhouses (Photo: Lisbeth Heilesen)

2014.08.11 | Research

Molecular geneticist at AU among the most frequently cited researchers in the world

Jens Stougaard is the only researcher from a Danish university among the 1% of the most frequently cited researchers in the field of Plant and Animal Science. He is a professor at the Department of Molecular Biology and Genetics, Aarhus University (AU), and is also director of the Centre for Carbohydrate Recognition and Signalling (CARB), a Centre…

The changes in the red and blue bands show the recently discovered local unfolding of PAI-1 just before it is inactivated. Also shown is how the green parts of proteins are rearranged in connection with the inactivation. Figure: Morten Beck Trelle and Peter A. Andreasen

2014.07.30 | Research

Breakthrough in exploration of protein dynamics

Using a uniquely informative technology, a team of Danish researchers has discovered a new type of peptide chain dynamics that controls the stability of the PAI-1 protein. The discovery provides a better basis in the long term for intervening in diseases associated with increased risk of blood clots.

With a new method, researchers use a piece of DNA engineered to bind to metal ions. Using this ‘control stick’, they direct another piece of DNA to a metal binding site on the protein. Illustration: Nature Chemistry

2014.07.30 | Research

New method provides researchers with efficient tool for tagging proteins

Aarhus University researchers have developed an easier method to create DNA–protein conjugates. The method can potentially strengthen the work involved in diagnosing diseases.

The genetics of several cattle breeds is now described in hitherto unseen details. Photo: Colourbox

2014.07.30 | Research

Cattle code cracked in detail

The cattle genome has now been mapped to a hitherto unknown degree of detail. This constitutes a quantum leap for research into the history and genetics of cattle.

The Danish research team behind the new results (from left): Jan K. Jensen, Michael Etzerodt, Anette Kjems and Bjarne Jochimsen (photo: Lisbeth Heilesen)
The Norwegian research team: Kaare Bjerregaard-Andersen, J. Preben Morth and Theis Sommer (photo: Oslo University)
Identification of two entrances to the active site, a combined water and proton channel and a substrate and product channel (figure: Kaare Bjerregaard-Andersen)

2014.06.30 | Research

Norwegian - Danish collaboration uncovers proton channel in a bacterial enzyme

A scientific collaboration between researchers from the University of Oslo and Aarhus University has revealed an unexpected channel for removal of protons in the enzyme isatin hydrolase.

At the beginning of an infection, the viral RNA is released inside the cell. The cellular protein RIG-I detects the viral RNA and initiates a defence mechanism that leads to the expression of the protein OASL. Later during the infection – when OASL is present in the infected cell – RIG-I recognises the viral RNA again , but by interacting with OASL, the initiated defence mechanism is enhanced, thereby fending of the virus more efficiently.

2014.06.23 | Public / media

Viral infections could be stopped by boosting natural protein

An international research team has published results showing that boosting the protein OASL may help the body to detect and fend off certain viral infections on its own. The discovery could lead to new, more effective treatments for many dangerous viruses such as hepatitis C and influenza.

2014.06.23 | Awards

Thomas Birkballe receives ST Science Award 2014

During ST's summer celebration on 20 June 2014, six ST awards were given. Postdoc Thomas Birkballe Hansen from MBG/iNANO received the ST Science Award.

Bjørn Panyella Pedersen (Photo: the Danish Council for Independent Research)
Sapere Aude: DFF-research leaders with Chairman of the Board Peter Munk Christiansen and Minister of Research Sofie Carsten Nielsen. Bjørn: front row, no. two from the right. (Photo: the Danish Council for Independent Research)

2014.06.18 | Public / media

Sapere Aude grant awarded to Bjørn Panyella Pedersen

With a Sapere Aude Starting Grant of more than DKK 7 million from the Danish Council for Independent Research, Bjørn P. Pedersen is assured of the best possible chance to return to Denmark and establish a structural biology research group at Aarhus University.

2014.06.18 | Public / media

Six researchers from MBG receive grants from the Danish Coucil for Independent Research

Jan J. Enghild, Kim Henrik Hebelstrup, Ian Max Møller, Lene Niemann Nejsum, Daniel Otzen and Claus Oxvig from MBG have all received large grants from The Danish Council for Independent Research.

The novel online learning platform has been developed to support the written exam skills of university students.
Associate Professor Ditlev Egeskov Brodersen from the Department of Molecular Biology and Genetics has developed the novel learning platform that will now be opened up to a wider audience at Aarhus University and other institutions in Denmark and abroad. Photo: Inger Marie Lindeman Olsen.

2014.06.11 | Public / media

Novel learning platform developed at AU

Today, Wednesday 11 June 2014, a novel learning platform is launched at Aarhus University, The platform has been developed by Associate Professor Ditlev Egeskov Brodersen at the Department of Molecular Biology and Genetics (MBG) and will be presented to the public on Thursday afternoon at a workshop at the conference "Frontiers in…

Deep roots help crops acquire water and nutrients. With the aid of new gene technologies scientists are developing crops with deeper roots. Photo: Colourbox

2014.06.10 | Public / media, Knowledge exchange

Deep roots are the root of all good

Scientists are developing deep-rooted crops for better uptake of water and nutrients. This will make the plants more robust and better able to cope with the expected effects of climate change on the weather and will ensure better growth and higher yields.

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