Structural Biology

Description of research

The research in structural biology is to a large degree based on x-ray crystallography as a method to determine the three-dimensional structure of biological macromolecules: proteins, nucleic acids, and sugars.

In addition, the section employs a range of other methods in structural biology including small-angle x-ray scattering (SAXS), circular dichroism (CD), and electron microscopy (EM). But the research of the section also covers a range of functional studies, such as single-molecule studies, electrophysiological studies of membrane proteins, enzymatic assays, which complement the investigation of molecular structure.

The research topics of the section range broadly from membrane proteins and receptors, to soluble enzymes and large protein complexes.

The research is primarily basic science with a wide scope, but some of the results can also be used for development of novel drugs.

The section for structural biology consists of six research groups led by professor Poul Nissen, associate professors Søren Thirup, Gregers Rom Andersen, Ditlev Egeskov Brodersen, Rune Hartmann and Charlotte Rohde Knudsen.

The section consists of 55 employees and students, including technicians and bachelor, exchange, and master's students, PhD students, post docs, and other permanent staff.

Section coordinator

Gregers Rom Andersen

Professor
M
H bldg. 3130, 204
P +4551446530
P +4530256646

Group leaders


Thomas Boesen

Cryo-EM Facility Manager

Ditlev Egeskov Brodersen

Associate professor
M
H bldg. 3130, 205
P +4521669001
P +4521669001

Rune Hartmann

Associate professor
M
H bldg. 3142, 124
P +4587155469
P +4528992578

Charlotte Rohde Knudsen

Associate professor
M
H bldg. FB06, 109
P +4587155437
P +4520572372

Esben Lorentzen

Associate professor
M
P +4587155478

Poul Nissen

Professor
M
H bldg. 3130, 2.02
P +4587155508
P +4528992295

Søren Skou Thirup

Associate professor
M
H bldg. 3130, 207
P +4587155464
P +4520585981

Junior group leaders


Magnus Kjærgaard

AIAS Cofund Junior Fellow

Bjørn Panyella Pedersen

AIAS Cofund Junior Fellow

Hanne Poulsen

Associate professor
M
H bldg. 3132, 101
P +4530254065
P +4530254065