Research

Research within Centre for Quantitative Genetics and Genomics (QGG) includes both basic and applied research. The research effort is centered on the genetic basis of complex traits in farm animals and model organisms. The core research process is development and implementation of advanced statistical and bioinformatic methods for analysis of genetics problems. The research within QGG is characterized by a very close synergy between method development, basic analyses and application of the developed methods on practical problems across animal species.

The research in QGG has four focus areas

  1. Quantitative genomics for predicting the genetic potential of single individuals
  2. Gene mapping and integrative genomics for understanding the genetic architecture of complex traits and diseases
  3. Population genomics for design and optimization of breeding programs and managing animal genetic resources
  4. Phenomics based on large-scale or advanced measuring technologies, e.g. automatic recordings, methane emissions, rumen microbiome, milk components etc.

Core competences

  • Development, implementation (e.g. as software) and application of statistical methods and genetic models for quantitative genetic and genomic analyses of complex health and production traits in farm animals
  • Genetic analyses including association and QTL mapping of traits performed on a number of important production organisms (cattle, pigs, poultry, mink, trout, rye grass) as well as model organism (mice, fruit flies)
  • Development and application of statistical and bioinformatic methods for identification of regions in the genome that influences molecular phenotypes (transcriptome, proteome and metabonome data) with special emphasis on providing insight into the regulatory genetic mechanisms in complex traits
  • Design and optimization of animal breeding programs including development of deterministic prediction tools and stochastic simulation software with special emphasis on the use of molecular information and breeding goals that ensures balance between high production and animal welfare
  • Strategies and criteria for conservation of genetic resources in farm, captive, and wild populations with special emphasis on preservation of adaptive genetic variation and reduction in the rate of inbreeding