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Understanding how cholesterol enters the cell



News

Bjørn Panyella Pedersen

2019.11.26 | Grant

Understanding how cholesterol enters the cell

Uptake of cholesterol needs to be tightly controlled, and too much cholesterol can lead to cardiovascular disease and other maladies. With a grant of 4.5 mio from the Carlsberg Foundation, Bjørn Panyella Pedersen from the Department of Molecular Biology and Genetics, Aarhus University, will aim at uncovering parts of this essential process. His…

With a grant from the Independent Research Fund Denmark’s Sapere Aude programme, Peter Refsing Andersen from the Department of Molecular Biology and Genetics and AIAS, Aarhus University, will uncover the strategies used by DNA parasites to evade the genomic defence mechanisms. Photo: Lisbeth Heilesen

2019.11.19 | Grant

Revealing how genes fight each other for space in the genome

Spread of DNA parasites can destroy important genes, so all forms of life have evolved genome defence mechanisms to keep the parasites in check. With a grant of DKK 6.2 mio. from the Independent Research Fund Denmark’s Sapere Aude programme, Peter Refsing Andersen from the Department of Molecular Biology and Genetics and AIAS, Aarhus University,…

A functional link between nuclear RNA decay and transcriptional control by the Polycomb Repressive Complex 2. In the absence of PAXT-mediated RNA decay, nuclear pA+ transcripts are stabilised. Excess RNA binds and out-titrates PRC2 from chromatin, and the interaction between complex subunits is disrupted. Normal PRC2-repressed loci show decreased H3K27me3 levels and correlates with increased an increase in transcription. Figure: Will Garland/AU

2019.11.15 | Research

RNA regulation is crucial for embryonic stem cell differentiation

Nuclear RNA levels are kept in check by RNA decay factors. Now, researchers at Aarhus and Copenhagen Universities show that an excess of RNA in the nucleus can have negative effects on a crucial regulator of stem cell differentiation.

Events

Thu 12 Dec
11:00-13:00 | Building 7613, room C101, Auditorium, Department of Molecular Biology and Genetics, Aarhus University, Flakkebjerg, Forsøgsvej 1, 4200 Slagelse
PhD defence: From pests to a source of resistance: Epichloë endophytes in grasses
Giovanni Cagnano
Wed 18 Dec
10:00-11:00 | The auditorium
Staff meeting for MBG Flakkebjerg
Fri 10 Jan
09:30-11:00 | Auditorium G1 (1532-116)
Guest lecture: Joint Double-Seminar Bioscience and Bioengineering

PhD defences

Giovanni Cagnano
Tall fescue endophyte (Epichloë coenophiala) mycelia colonizing the intercellular spaces of the host tiller. The endophyte mycelium is stained with alanine blue. Photo: Carolyn Young.

2019.12.12 | PhD defense

Giovanni Cagnano: From pests to a source of resistance: Epichloë endophytes in grasses

PhD defence, Thursday 12 December 2019. Giovanni Cagnano.