During his PhD studies, Andreas Bjerregaard Kamstrup researched novel circular RNAs in bladder cancer. Circular RNAs have within the last decade emerged as a highly diverse class of non-coding RNA and demonstrated to be functionally involved in a broad range of biological processes. Despite of this, the majority of circular RNAs remain enigmatic and their involvement in tumorigenesis is poorly understood. Andreas Bjerregaard Kamstrup studied how a circular RNA from the TULP4 gene is involved in regulation of cell cycle progression and fundamental cellular signal transduction pathways.

The new research findings contribute to our understanding of the functional role of circular RNAs and their involvement in biological processes related to cancer and tumorigenesis.

The PhD study was completed at Department of Molecular Biology and Genetics, Faculty of Technical Sciences, Aarhus University.

This summary was prepared by the PhD student.

Time: Thursday, 6 May 2021 at 13:00
Place: The PhD defence will be held online. To receive a link to the event, please send an e-mail to Tina Stenshøj Kaysen tist@au.dk.
Title of PhD thesis: Circular RNAs in bladder cancer: CircTULP4 as a regulator of cell cycle progression and cell signaling

Contact information: Andreas Bjerregaard Kamstrup, e-mail: kamstrup@mbg.au.dk, tel.: +45 20288005

Members of the assessment committee:

Associate professor  Lisa Frankel, Biotech research and innovation center (BRIC), Copenhagen University, DK
Professor Javier Caceres, MRC Institute of Genetics & Molecular Medicine, University of Edinburgh, UK
Associate Professor Anni Hangaard Andersen, Department of Molecular Biology and Genetics, Aarhus University (chair) Denmark

Main supervisor:
Associate Professor Christian Kroun Damgaard, Department of  Molecular Biology and Genetics, Aarhus University, Denmark

Language: The PhD dissertation will be defended in English

The defence is public.
Due to the coronavirus situation, the PhD thesis will not be available for reading at the offices of the PhD administration. Instead, interested parties may send an e-mail to gradschool.tech@au.dk to receive a digital copy of the PhD thesis. Please note, it may in certain cases be necessary to make an individual arrangement to read the PhD thesis.