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Claudia Iasillo: Relationship between RNA transcription and RNA processing

PhD defence, Wednesday 26 October 2016. Claudia Iasillo16. Claudia Iasillo

Claudia Iasillo

During her PhD studies Claudia Iasillo researched the activity of some proteins involved in RNA biogenesis. RNA is transcribed in the nucleus of eukaryotic cells from a DNA template by specific enzymes called RNA polymerases. Different RNA species are synthesized by different RNA polymerases. During or after their synthesis, RNAs undergo general maturation processes in order to become functional. By applying high-throughput sequencing approaches, Claudia investigated the interactions between proteins involved both in RNA synthesis and RNA processing. These interactions pointed out the importance of the protein ARS2 in the regulation of RNA metabolism.  

The new findings of her research contribute to shed light on the specific role of ARS2 and some of its interactors in the biogenesis of different RNA species.


The PhD degree was completed at the Department of Molecular Biology and Genetics, Aarhus University.

This résumé was prepared by the PhD student.

Time: Wednesday 26 October 2016 at 12:30
Place:
Building 3130, room 303, Conference room Science Park, Gustav Wieds Vej 10C, 8000 Aarhus C
Title of dissertation:
Role of CBCA in RNA biogenesis
Contact information
: Claudia Iasillo, e-mail: iasillo@mbg.au.dk
Members of the assessment committee
:
Permanent researcher - CR1 INSERM, HDR Martin Dutertre, UMR 3348 CNRS Institut Curie - Centre de Recherche, Université Paris Sud, France
Associate professor Klaus Hansen, Biotech Research & Innovation Centre (BRIC), Copenhagen University
Professor Claus Oxvig (chair), Department of Molecular Biology and Genetics, Aarhus University
Main supervisor
:
Professor Torben Heick Jensen, Department of Molecular Biology and Genetics, Aarhus University
Co-supervisor:
Dr. Edouard Bertrand, Institut de Génétique Moléculaire de Montpellier (IGMM), Montpellier, France
Language:
The PhD dissertation will be defended in English

The defence is public.
The dissertation is available for reading at the Graduate School of Science and Technology/GSST, Ny Munkegade 120, building 1520, rooms 128-134, 8000 Aarhus