During his PhD studies, Liviu I. Moldovan researched the involvement of circRNAs in the inflammatory skin diseases, namely psoriasis and atopic dermatisis (AD). These are two  of the most common chronic

skin conditions in adults worldwide, with a considerable negative impact on life quality. Liviu I. Moldovan studied the circRNA transcriptome in psoriasis and AD by shedding a light on altered circRNA expression between lesional and non-lesional skin from patients and by contrasting it with skin from healthy individuals. The new research findings raise interesting questions related to new pathophysiological mechanisms in inflammatory skin disease and present compelling evidence for the great biomarker potential of circRNAs.

The PhD study was completed at the Interdisciplinary Nanoscience Center (iNano) amd Department of Molecular Biology and Genetics, Faculty of Natural Sciences, Aarhus University.

This summary was prepared by the PhD student.

Time: Friday 5 February 2021 at 9.15
Place: The PhD defence will be held online.
To receive a link to the event, please send an e-mail to Jørgen Kjems, jk@mb.au.dk.
Title of PhD thesis: circRNAs: New biomarkers in inflammatory skin diseases?
Contact information: Liviu I. Moldovan, e-mail: liviu.mldvn@biomed.au.dk, tel.: +45 61371991
Members of the assessment committee:
Professor Lone Skov, Department of Dermato-Allergology, Gentofte Hospital, Faculty of Health Sciences, University of Copenhagen, Denmark
Senior researcher Ling-Ling Chen, Shanghai Institute of Biochemistry and Cell Biology, China
Associate Professor Ken Howard (chairman), Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Denmark
Main supervisor:
Professor  Jørgen Kjems, Interdisciplinary Nanoscience Center (iNANO) and Molecular Biology and Genetics, Aarhus University, Denmark
Co-supervisor:
Associate Professor Lasse Sommer Kristensen, Biomedicine, Aarhus University, Denmark
Language: The PhD dissertation will be defended in English

The defence is public.

Due to the coronavirus situation, the PhD thesis will not be available for reading at the offices of the PhD administration. Instead, interested parties may send an e-mail to gradschool.nat@au.dk to receive a digital copy of the PhD thesis. Please note, it may in certain cases be necessary to make an individual arrangement to read the PhD thesis.