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PhD defence: Unraveling the mysteries of circular RNAs – how and why are they produced?

PhD defence, Friday 20 September 2019, Lotte Victoria Winther Stagsted.

Lotte Stagsted

Circular RNA differs from other RNA subtypes by adapting a unique closed circular structure, which makes them highly stable molecules and argues for important functions within cells. Circular RNAs have been shown to regulate the activity of other RNAs and proteins, however, their physiological role and relevance is still unclear.

During her PhD studies, Lotte V. W. Stagsted has investigated the contribution of regulatory genomic elements and proteins that are involved in the production of circular RNAs. Furthermore, she has studied the functional capabilities of circular RNAs in great detail. These new research findings shine important light on how and why circular RNAs are produced, as well as contributing to the understanding of the cellular processes governing gene expression.

The PhD degree was completed at the Department of Molecular Biology and Genetics, Science and Technology, Aarhus University.

This résumé was prepared by the PhD student.

Time: Friday 20th of September 2019 at 13.00
Place: Building 1532, room 122, Lecture Theatre G2, Aarhus University
Title of PhD thesis: Biogenesis and functions of circular RNAs
Contact information: Lotte Victoria Winther Stagsted, e-mail: lvws@mbg.au.dk, tel.: +45 31512733
Members of the assessment committee:
Associate Professor Peter Brodersen, Department of Biology, University of Copenhagen
Professor Gunter Meister, Department of Biochemistry, Universität Regensburg, Germany
Associate Professor Anni Hangaard Andersen (chair), Department of Molecular Biology and Genetics, Aarhus University
Main supervisor:
Assistant Professor Thomas Birkballe Hansen, Department of Molecular Biology and Genetics, Aarhus University
Co-supervisor:
Associate Professor Christian Kroun Damgaard, Department of Molecular Biology and Genetics, Aarhus University
Language: The PhD dissertation will be defended in English

The defence is public.
The PhD thesis is available for reading at the Graduate School of Science and Technology/GSST, Ny Munkegade 120, building 1521, 8000 Aarhus C.