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The photo shows two nodules on the root of the legume <em>Lotus japonicus</em>. This plant has symbiosis with the soil bacterium <em>Mesorhizobium loti</em>. In the symbiosis, the bacteria get carbohydrates from the plant, and the bacterium delivers fixed nitrogen to the plant. Therefore, the plant can do without nitrogen fertilizer. The bacteria are stained for the LacZ enzyme (dark blue) and the plant's nuclei are stained with DAPI. The nuclei are seen as light blue dots. You can see the bacteria in the young nodule and on the surface of the older nodule. In the research group - The Section for Plant Molecular Biology at the Department of Molecular Biology and Genetics - the researchers have isolated many of the plant genes necessary for the symbiosis.

2019.03.28 | Awards

Niels Sandal wins the prize for the science photo of the year 2019

The Danish National Research Foundation and videnskab.dk have invited researchers to participate in a photo competition on photos from their research. The judging committee selected Niels Sandal's photo with two nodules on the root of the leguminous plant Lotus japonicus as the science photo of 2019.

Professor Rune Hartmann (left) and Postdoc Hans Henrik Gad have - in collaboration with German and Swedish research groups - shown how a protein called IFN-λ can both fight a viral infection directly, but also boost the formation of new antibodies against the virus. Photo: Lisbeth Heilesen, AU.

2019.03.19 | Research

When the immune system is multitasking

An international research team has shown how a protein called IFN-λ can both fight a viral infection directly, but also boost the formation of new antibodies against the virus. The discovery gives new important knowledge about how different parts of the immune system communicate and will make it easier to make more effective vaccines, especially…

The methane content of cow burps can be reduced and the cows' feed efficiency improved at the same time with targeted breeding. Photo: Jesper Rais

2019.02.27 | Research

Both the climate and farm economy can come out on top

With the aid of low-cost, high-capacity recording methods, dairy cattle farmers can reduce the amount of greenhouse gases that their cows burp while at the same time improving the animals’ feed efficiency.

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A research group has just elucidated the structure of a sugar transport protein that is unique to plants. The new structure can help explain how plant organs - such as pollen - develop properly, and give ideas as to why some subspecies of wheat are resistant to fungal attacks. Figures: Bjørn Panyella Pedersen.

2019.01.25 | Research

New insight into unique sugar transport in plants

A small research group at Aarhus University has just elucidated the structure of a sugar transport protein that is unique to plants. The new structure can help explain how plant organs - such as pollen - develop properly, and give ideas as to why some subspecies of wheat are resistant to fungal attacks.

Professor Jan J. Enghild has received a grant from the Novo Nordisk Foundation of EUR 2 million to buy high-tech equipment for biological mass spectroscopy. Photo: Lisbeth Heilesen, AU.

2019.01.22 | Grant

High-tech equipment for biological mass spectroscopy

With a grant from the Novo Nordisk Foundation of EUR 2 million (DKK 15 million), Professor Jan J. Enghild can pursue his vision of establishing a "state-of-the-art" platform within biological mass spectroscopy.

Professor Torben Heick Jensen receives DKK 60 million from the Novo Nordisk Foundation to establish the research center 'Exo-Adapt', which will determine how our cells sort genetic information. Photo: Lisbeth Heilesen.

2019.01.08 | Grant

60 million Danish kroner for basic biomedical research

Professor Torben Heick Jensen, Department of Molecular Biology and Genetics, Aarhus University, receives DKK 60 million (Euro 8 million) from the Novo Nordisk Foundation's Challenge Programme to establish the research center 'Exo-Adapt', which will determine how our cells sort genetic information.

Gregers Rom Andersen (left) and Poul Nissen participate in a new three-year EU project, which has received a grant from the EU of EUR 3.6 million. Photo: Lisbeth Heilesen
The HALOS collaboration includes eight academic research institutes in Sweden, Denmark, Norway and Germany, MAX IV and ESS in Sweden, DESY and the European XFEL in Germany, the Medicon Valley Alliance (MVA), industry in MedTech, BioTech and Pharma, Region Skåne, the Capital Region of Denmark and the City of Hamburg. Figure: Lund University

2019.01.02 | Grant

Aarhus University participates in a new Oresund-Kattegat-Skagerak EU Life Science Network

Gregers Rom Andersen and Poul Nissen from the Department of Molecular Biology and Genetics, Aarhus University, participate in a new three-year EU project for the Oresund-Kattegat-Skagerak (OKS) area, which has received a grant from the EU of EUR 3.6 million.

The cow's genetics and changes in her rumen flora can affect how much methane she emits. Photo: Janne Hansen

2018.12.12 | Research

Methane from cow burps can be reduced by a two-front approach

Combing a cow’s own genetics with strategies that target changes in her rumen flora may be able to reduce methane emissions more effectively than by only selecting for low methane-emitting cows.

2018.12.06 | Grant

Six researchers from MBG receive a grant from the Novo Nordisk Foundation

The Novo Nordisk Foundation has awarded a total of 51 grants for project support in Life Sciences and Basic Biomedicine. Of this, six MBG researchers have been granted a grant.

The Bioinnovation Institute has  a total of 12,000 m2 at its disposal and is housed in Copenhagen. Photo: The Novo Nordisk Foundation.
Poul Nissen has been appointed as an expert to assist the Novo Nordisk Foundation to find the best researchers in the life science area for their new incubation programmes at the Bioinnovation Institute. Photo: Lisbeth Heilesen

2018.11.29 | People

New incubation programmes from the Novo Nordisk Foundation

The Novo Nordisk Foundation's new Bioinnovation Institute (BII) has appointed a panel from universities, venture funds and life science companies to help assess applications for their new incubation programmes.

With a new project, researchers hope to be able to develop "artificial tasting machines". Photo: Colourbox

2018.11.20 | Grant

DNA molecules will be used to mimic human sense of taste

Human sense of taste is complex and difficult to imitate. An interdisciplinary project is now aiming at developing extremely fast "artificial tasting machines" that use DNA molecules as billions of small "sensors" to imitate human sense of taste with unprecedented accuracy.

Professor Gregers Rom Andersen (left), Cryo-EM Facility Manager Thomas Boesen and Professor Poul Nissen in front of the Titan-Krios flagship microscope at Aarhus University (photo: Lisbeth Heilesen).

2018.11.08 | Grant

DKK 30 million for high-tech electron microscopes for research in molecular cell biology

The Minister for Higher Education and Science has approved funding for three new research infrastructures, of which DKK 30.76 million goes to EMBION – a research infrastructure for cryo-electron microscopy (cryo-EM) on biological materials.

Each individual domain antibody neutralizes a subset of influenza virus subtypes. However, when the domains are fused in to a multi-domain antibody the protein is able to neutralize a broad number of influenza virus subtypes. Figure: Nick Stub Laursen.
A llama was immunized with an influenza vaccine and an HA protein. Domain antibodies that neutralizes influenza virus were isolated and combined into a multi-domain antibody (MdAb). The MdAb gene was inserted into an adeno-associated virus (AAV) that was administered to mice for local expression of the MdAb, which protected the mice from subsequent infection with influenza virus. Atomic structures of influenza virus HA in complex with different domain antibodies. The trimeric HA molecule is shown in gray and the domain antibodies colored in blue, magenta, green and red. Figure: Nick Stub Laursen.

2018.11.02 | Research

Researches develop new protein for prevention of influenza virus infection

An international research team has developed a new protein drug which has the potential to be used for protection against all types of influenza infection. By delivering the drug as a DNA vector it may also function as a universal influenza vaccine.

Researchers are using New Breeding Techniques to improve crop yield and quality. The knowledge they create will be put to practical use in collaboration with the industry. Photo: Colourbox

2018.11.11 | Grant

Modern breeding technology can increase Denmark’s share of the market

Methods that are being developed in a new research project can strengthen Denmark’s competitive edge on the international market for crop seeds.

Structural representation of the crystal structure of the protein kinase RSK2 (grey surface) in complex with the drug dimethyl fumarate (yellow spheres). The light blue spheres represent water molecules bound to the protein structure that are also revealed from the crystal structure. The structure was determined at 1.9 Å resolution and the atomic coordinates are available in the protein data bank with access code 5O1S: www.rcsb.org/structure/5O1S
Model of DMF inhibition. Schematic figure of the activation loop transition between inactive and activated state of the C-terminal kinase domain (consisting of the ATP binding domain and the helix bundle domain). DMF targets an allosteric site and blocks kinase activation, and vice versa. Figure: Jacob Lauwring Andersen

2018.10.31 | Research

New insight into the mechanism of the drug against sclerosis and psoriasis

A multidisciplinary research team at Aarhus University has provided fundamental new insight into the mechanism of the medical drug dimethyl fumarate, which is the active component of important treatments for multiple sclerosis and psoriasis. The results contribute to the development of new strategies for drug discovery.

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