2018

Conover, C. A. & Oxvig, C. (2018). 40 years of IGF1: PAPP-A and cancer. Journal of Molecular Endocrinology, 61(1), T1-T10. https://doi.org/10.1530/JME-17-0236

Holleufer, A. (2018). A Highly Sensitive Anion Exchange Chromatography Method for Measuring cGAS Activity in vitro. Bio-protocol, 8(20). https://doi.org/10.21769/BioProtoc.3055

Tsikou, D., Ramirez, E. E., Psarrakou, I. S., Wong, J. E., Jensen, D. B., Isono, E., Radutoiu, S. & Papadopoulou, K. K. (2018). A Lotus japonicus E3 ligase interacts with the Nod Factor Receptor 5 and positively regulates nodulation. BMC Plant Biology, 18(1), [217]. https://doi.org/10.1186/s12870-018-1425-z

Wong, A., Bryzek, D., Dobosz, E., Scavenius, C., Svoboda, P., Rapala-Kozik, M., Lesner, A., Frydrych, I., Enghild, J., Mydel, P., Pohl, J., Thompson, P. R., Potempa, J. & Koziel, J. (2018). A Novel Biological Role for Peptidyl-Arginine Deiminases: Citrullination of Cathelicidin LL-37 Controls the Immunostimulatory Potential of Cell-Free DNA. Journal of Immunology, 200(7), 2327-2340. https://doi.org/10.4049/jimmunol.1701391

Tudek, A., Schmid, M., Makaras, M., Barrass, J. D., Beggs, J. D. & Jensen, T. H. (2018). A Nuclear Export Block Triggers the Decay of Newly Synthesized Polyadenylated RNA. Cell Reports, 24(9), 2457-2467.e7. https://doi.org/10.1016/j.celrep.2018.07.103

Rouvière, J. O., Bulfoni, M., Tuck, A., Cosson, B., Devaux, F. & Palancade, B. (2018). A SUMO-dependent feedback loop senses and controls the biogenesis of nuclear pore subunits. Nature Communications, 9, [1665]. https://doi.org/10.1038/s41467-018-03673-3

Hennessy, R. C., Jørgensen, N. O. G., Scavenius, C., Enghild, J. J., Greve-Poulsen, M., Sørensen, O. B. & Stougaard, P. (2018). A Screening Method for the Isolation of Bacteria Capable of Degrading Toxic Steroidal Glycoalkaloids Present in Potato. Frontiers in Microbiology, 9, [2648]. https://doi.org/10.3389/fmicb.2018.02648

Al-Khafaji, H., Noer, P. R., Alkharobi, H., Alhodhodi, A., Meade, J., El-Gendy, R., Oxvig, C. & Beattie, J. (2018). A characteristic signature of insulin-like growth factor (IGF) axis expression during osteogenic differentiation of human dental pulp cells (hDPCs): Potential co-ordinated regulation of IGF action. Growth Hormone and IGF Research, 42-43, 14-21. https://doi.org/10.1016/j.ghir.2018.07.003

Engelke, C., Lange-Asschenfeldt, C., Peter, S., Kahl, K. G., Frasch, K., Larsen, J. I., Bickel, G. G., Bork, B., Jacobsen, B. A., Wallenstein-Jensen, S. O., Lauber, C., Mogensen, B., Nielsen, J. A., Rössler, W., Tsuchiya, K. J., Toftegaard, K. L., Andersen, U. A., Uwakwe, R., Munk-Jørgensen, P. & Cordes, J. (2018). A cross-continental analysis of weight gain, psychiatric diagnoses and medication use during inpatient psychiatric treatment. The international study on physical illness in mentally ill. European Psychiatry, 48, 65-70. https://doi.org/10.1016/j.eurpsy.2017.11.004

Sommer, T., Bjerregaard-Andersen, K., Uribe, L., Etzerodt, M., Diezemann, G., Gauss, J., Cascella, M. & Morth, J. P. (2018). A fundamental catalytic difference between zinc and manganese dependent enzymes revealed in a bacterial isatin hydrolase. Scientific Reports, 8(1), [13104]. https://doi.org/10.1038/s41598-018-31259-y

Liu, H., Sandal, N., Andersen, K. R., James, E. K., Stougaard, J., Kelly, S. & Kawaharada, Y. (2018). A genetic screen for plant mutants with altered nodulation phenotypes in response to rhizobial glycan mutants. New Phytologist, 220(2), 526-538. https://doi.org/10.1111/nph.15293

Knudsen, C. H., ásgrímsdóttir, E. S., Rahimi, K., Gill, K. P., Frandsen, S., Buchholdt, S. H., Chen, M., Kjems, J., Febbraro, F. & Denham, M. (2018). A modified monomeric red fluorescent protein reporter for assessing CRISPR activity. Frontiers in Cell and Developmental Biology, 6(MAY), [54]. https://doi.org/10.3389/fcell.2018.00054

Sampedro Castañeda, M., Zanoteli, E., Scalco, R. S., Scaramuzzi, V., Marques Caldas, V., Conti Reed, U., da Silva, A. M. S., O'Callaghan, B., Phadke, R., Bugiardini, E., Sud, R., McCall, S., Hanna, M. G., Poulsen, H., Männikkö, R. & Matthews, E. (2018). A novel ATP1A2 mutation in a patient with hypokalaemic periodic paralysis and CNS symptoms. Brain : a journal of neurology, 141(12), 3308-3318. https://doi.org/10.1093/brain/awy283

Malolepszy, A., Kelly, S., Sørensen, K. K., James, E. K., Kalisch, C., Bozsoki, Z., Panting, M., Andersen, S. U., Sato, S., Tao, K., Jensen, D. B., Vinther, M., Jong, N. D., Madsen, L. H., Umehara, Y., Gysel, K., Berentsen, M. U., Blaise, M., Jensen, K. J. ... Radutoiu, S. (2018). A plant chitinase controls cortical infection thread progression and nitrogen-fixing symbiosis. eLife, 7, 1-17. [38874]. https://doi.org/10.7554/eLife.38874

Jensen, R. K., Pihl, R., Gadeberg, T. A. F., Jensen, J. K., Andersen, K. R., Thiel, S., Laursen, N. S. & Andersen, G. R. (2018). A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement. Journal of Biological Chemistry, 293(17), 6269-6281. https://doi.org/10.1074/jbc.RA117.001179

Rattan, S., Demirovic, D. & Nizard, C. (2018). A preliminary attempt to establish multiple stress response profiles of human skin fibroblasts exposed to mild or severe stress during ageing in vitro. Mechanisms of Ageing and Development, 170(March), 92-97. https://doi.org/10.1016/j.mad.2017.09.005

Yatime, L., Merle, N. S., Hansen, A. G., Friis, N. A., Østergaard, J. A., Bjerre, M., Roumenina, L. T., Thiel, S., Kristensen, P. & Andersen, G. R. (2018). A single-domain antibody targeting complement component c5 acts as a selective inhibitor of the terminal pathway of the complement system and thus functionally mimicks the c-terminal domain of the staphylococcus aureusSSL7 protein. Frontiers in Immunology, 9, [2822]. https://doi.org/10.3389/fimmu.2018.02822

Perego, M., Maurer, M., Wang, J. X., Shaffer, S., Müller, A. C., Parapatics, K., Li, L., Hristova, D., Shin, S., Keeney, F., Liu, S., Xu, X., Raj, A., Jensen, J. K., Bennett, K. L., Wagner, S. N., Somasundaram, R. & Herlyn, M. (2018). A slow-cycling subpopulation of melanoma cells with highly invasive properties. Oncogene, 37, 302-312. https://doi.org/10.1038/onc.2017.341

Compte, M., Harwood, S. L., Muñoz, I. G., Navarro, R., Zonca, M., Perez-Chacon, G., Erce-Llamazares, A., Merino, N., Tapia-Galisteo, A., Cuesta, A. M., Mikkelsen, K., Caleiras, E., Nuñez-Prado, N., Aznar, M. A., Lykkemark, S., Martínez-Torrecuadrada, J., Melero, I., Blanco, F. J., Bernardino de la Serna, J. ... Alvarez-Vallina, L. (2018). A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity. Nature Communications, 9, [4809 ]. https://doi.org/10.1038/s41467-018-07195-w

Jacobsen, K. M., Villadsen, N. L., Tørring, T., Nielsen, C. B., Salomón, T., Nielsen, M. M., Tsakos, M., Sibbersen, C., Scavenius, C., Nielsen, R., Christensen, E. I., Guerra, P. F., Bross, P., Pedersen, J. S., Enghild, J. J., Johannsen, M., Frøkiær, J., Overgaard, J., Horsman, M. R. ... Poulsen, T. B. (2018). APD-Containing Cyclolipodepsipeptides Target Mitochondrial Function in Hypoxic Cancer Cells. Cell Chemical Biology, 25(11), 1337-1349. https://doi.org/10.1016/j.chembiol.2018.07.010

Stambler, I., jin, K., Lederman, S., Barzilai, N., Olshansky, S. J., Omokaro, E., Barratt, J., Anisimov, V., Rattan, S., Yang, S., Forster, M. & Byles, J. (2018). Aging Health and R&D for Healthy Longevity Must Be Included into the WHO Work Program. Aging and Disease, 9(2), 331-333. https://doi.org/10.14336/AD.2017.1120

Ferrando, B., Gomez-Cabrera, M. C., Salvador-Pascual, A., Puchades, C., Derbré, F., Gratas-Delamarche, A., Laparre, L., Olaso-Gonzalez, G., Cerda, M., Viosca, E., Alabajos, A., Sebastiá, V., Alberich-Bayarri, A., Garciá-Castro, F. & Vinã, J. (2018). Allopurinol partially prevents disuse muscle atrophy in mice and humans. Scientific Reports, 8(1), [3549]. https://doi.org/10.1038/s41598-018-21552-1

He, F., Bhoobalan-Chitty, Y., Van, L. B., Kjeldsen, A. L., Dedola, M., Makarova, K. S., Koonin, E. V., Brodersen, D. E. & Peng, X. (2018). Anti-CRISPR proteins encoded by archaeal lytic viruses inhibit subtype I-D immunity. Nature Microbiology, 3, 461-469. https://doi.org/10.1038/s41564-018-0120-z

Fedosov, S., Nexø, E. & Heegaard, C. W. (2018). Binding of aquocobalamin to bovine casein and its peptides via coordination to histidine residues. International Dairy Journal, 76, 30-39. https://doi.org/10.1016/j.idairyj.2017.08.005

Rattan, S. I. S. (2018). Biogerontology: research status, challenges and opportunities. Acta bio-medica : Atenei Parmensis, 89(2), 291-301. https://doi.org/10.23750/abm.v89i2.7403

Jensen, K., Harwood, S. L., Compte, M., Merino, N., Bonet, J., Álvarez-Cienfuegos, A., Mikkelsen, K., Alanes, N. N. D. P., Álvarez-Méndez, A., Sanz, L., Blanco, F. J. & Álvarez-Vallina, L. (2018). Bispecific light T-cell engagers for gene-based immunotherapy of epidermal growth factor receptor (EGFR)-positive malignancies. Cancer Immunology, Immunotherapy, 67(8), 1251-1260. https://doi.org/10.1007/s00262-018-2181-5

Lykke-Andersen, S., Ardal, B. K., Hollensen, A. K., Damgaard, C. K. & Jensen, T. H. (2018). Box C/D snoRNP Autoregulation by a cis-Acting snoRNA in the NOP56 Pre-mRNA. Molecular Cell, 72(1), 99-111.e1-e5. https://doi.org/10.1016/j.molcel.2018.08.017

Olesen, M. N., Christiansen, J. R., Petersen, S. V., Jensen, P. H., Paslawski, W., Romero-Ramos, M. & Sanchez-Guajardo, V. (2018). CD4 T cells react to local increase of α-synuclein in a pathology-associated variant-dependent manner and modify brain microglia in absence of brain pathology. Heliyon, 4(1), [e00513]. https://doi.org/10.1016/j.heliyon.2018.e00513

Song, W., Yang, C., Svend Le, D. Q., Zhang, Y. & Kjems, J. (2018). Calcium-microRNA Complexes Functionalized Nanotubular Implant Surface for Highly Efficient Transfection and Enhanced Osteogenesis of Mesenchymal Stem Cells. A C S Applied Materials and Interfaces, 10(9), 7756-7764. https://doi.org/10.1021/acsami.7b18289

Liu, C., Liu, Y., Larsen, K. E., Hou, Y. . & Callesen, H. (2018). Calcium-sensing receptor (CASR) is involved in porcine in-vitro fertilisation and early embryo development. Reproduction, Fertility and Development, 30(2), 391-398. https://doi.org/10.1071/RD16338

Prasad Rao, R. S., Zhang, N., Xu, D. & Max Møller, I. (2018). CarbonylDB: A curated data-resource of protein carbonylation sites. Bioinformatics, 34(14), 2518-2520. https://doi.org/10.1093/bioinformatics/bty123

Chen, M., Laursen, S. H., Habekost, M., Knudsen, C. H., Buchholdt, S. H., Huang, J., Xu, F., Liu, X., Bolund, L., Luo, Y., Nissen, P., Febbraro, F. & Denham, M. (2018). Central and peripheral nervous system progenitors derived from human pluripotent stem cells reveal a unique temporal and cell-type specific expression of PMCAs. Frontiers in Cell and Developmental Biology, 6, [5]. https://doi.org/10.3389/fcell.2018.00005

Wang, W. Q., Wang, Y., Zhang, Q., Møller, I. M. & Song, S. Q. (2018). Changes in the mitochondrial proteome of developing maize seed embryos. Physiologia Plantarum, 163(4), 552-572. https://doi.org/10.1111/ppl.12725

Zhang, M., Lykke-Andersen, S., Zhu, B., Xiao, W., Hoskins, J. W., Zhang, X., Rost, L. M., Collins, I., Bunt, M. V. D., Jia, J., Parikh, H., Zhang, T., Song, L., Jermusyk, A., Chung, C. C., Zhu, B., Zhou, W., Matters, G. L., Kurtz, R. C. ... Amundadottir, L. (2018). Characterising cis-regulatory variation in the transcriptome of histologically normal and tumour-derived pancreatic tissues. Gut, 67(3), 521-533. https://doi.org/10.1136/gutjnl-2016-313146

Kjeldsen, E., Nielsen, C. J. F., Roy, A., Tesauro, C., Jakobsen, A-K., Stougaard, M. & Knudsen, B. R. (2018). Characterization of Camptothecin-induced Genomic Changes in the Camptothecin-resistant T-ALL-derived Cell Line CPT-K5. Cancer Genomics & Proteomics, 15(2), 91-114. https://doi.org/10.21873/cgp.20068

Winczura, K., Schmid, M., Iasillo, C., Molloy, K. R., Harder, L. M., Andersen, J. S., LaCava, J. & Jensen, T. H. (2018). Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions. Cell Reports, 22(1), 44-58. https://doi.org/10.1016/j.celrep.2017.12.037

Barbagallo, D., Caponnetto, A., Cirnigliaro, M., Brex, D., Barbagallo, C., D’Angeli, F., Morrone, A., Caltabiano, R., Barbagallo, G. M., Ragusa, M., Di Pietro, C., Hansen, T. B. & Purrello, M. (2018). CircSMARCA5 inhibits migration of glioblastoma multiforme cells by regulating a molecular axis involving splicing factors SRSF1/SRSF3/PTB. International Journal of Molecular Sciences, 19(2), [480]. https://doi.org/10.3390/ijms19020480

Kristensen, L. S., Okholm, T. L. H., Venø, M. T. & Kjems, J. (2018). Circular RNAs are abundantly expressed and upregulated during human epidermal stem cell differentiation. RNA Biology, 15(2), 1-12. https://doi.org/10.1080/15476286.2017.1409931

Stoll, L., Sobel, J., Rodriguez-Trejo, A., Guay, C., Lee, K., Venø, M. T., Kjems, J., Laybutt, D. R. & Regazzi, R. (2018). Circular RNAs as novel regulators of β-cell functions in normal and disease conditions. Molecular Metabolism, 9, 69-83. https://doi.org/10.1016/j.molmet.2018.01.010

Kristensen, L. S., Hansen, T. B., Venø, M. T. & Kjems, J. (2018). Circular RNAs in cancer: opportunities and challenges in the field. Oncogene, 37, 555–565. https://doi.org/10.1038/onc.2017.361

Jiang, L., Oldenburg, E., Kromann-Hansen, T., Xu, P., Jensen, J. K., Andreasen, P. A. & Huang, M. (2018). Cleavage of peptidic inhibitors by target protease is caused by peptide conformational transition. Biochimica et Biophysica Acta - General Subjects, 1862(9), 2017-2023. https://doi.org/10.1016/j.bbagen.2018.06.016

Schmid, M. & Jensen, T. H. (2018). Controlling nuclear RNA levels. Nature Reviews. Genetics, 19, 518-529. https://doi.org/10.1038/s41576-018-0013-2

Stenvang, M., Schafer, N. P., Malmos, K. G., Pérez, A-M. W., Niembro, O., Sormanni, P., Basaiawmoit, R. V., Christiansen, G., Andreasen, M. & Otzen, D. E. (2018). Corneal dystrophy mutations drive pathogenesis by targeting TGFBIp stability and solubility in a latent amyloid-forming domain. Journal of Molecular Biology, 430(8), 1116-1140. https://doi.org/10.1016/j.jmb.2018.03.001

Beattie, J., Al-Khafaji, H., Noer, P. R., Alkharobi, H. E., Alhodhodi, A., Meade, J., El-Gendy, R. & Oxvig, C. (2018). Corrigendum: Insulin-like growth factor-binding protein action in bone tissue: A key role for pregnancy-associated plasma protein - A (Frontiers in Endocrinology (2018) 9:31 DOI: 10.3389/fendo.2018.00031). Frontiers in Endocrinology, 9(SEP), [510]. https://doi.org/10.3389/fendo.2018.00510