2020

Iparraguirre, L., Alberro, A., Sepúlveda, L., Osorio-Querejeta, I., Moles, L., Castillo-Triviño, T., Hansen, T. B., Muñoz-Culla, M. & Otaegui, D. (2020). RNA-Seq profiling of leukocytes reveals a sex-dependent global circular RNA upregulation in multiple sclerosis and 6 candidate biomarkers. Human Molecular Genetics, 29(20), 3361-3372. https://doi.org/10.1093/hmg/ddaa219

Martins, P. M., Navarro, S., Silva, A., Pinto, M. F., Sárkány, Z., Figueiredo, F., Pereira, P. J. B., Pinheiro, F., Bednarikova, Z., Burdukiewicz, M., Galzitskaya, O. V., Gazova, Z., Gomes, C. M., Pastore, A., Serpell, L. C., Skrabana, R., Smirnovas, V., Ziaunys, M., Otzen, D. E. ... Macedo-Ribeiro, S. (2020). MIRRAGGE - Minimum Information Required for Reproducible AGGregation Experiments. Frontiers in Molecular Neuroscience, 13, [582488]. https://doi.org/10.3389/fnmol.2020.582488

Harwood, S. L., Nielsen, N. S., Pedersen, H., Kjøge, K., Nielsen, P. K., Andersen, G. R. & Enghild, J. J. (2020). Substituting the Thiol Ester of Human A2M or C3 with a Disulfide Produces Native Proteins with Altered Proteolysis-Induced Conformational Changes. Biochemistry, 59(51), 4799–4809. https://doi.org/10.1021/acs.biochem.0c00803

Morgante, F., Huang, W., Sørensen, P., Maltecca, C. & Mackay, T. F. C. (2020). Leveraging Multiple Layers of Data To Predict Drosophila Complex Traits. G3 (Bethesda, Md.), 10(12), 4599-4613. https://doi.org/10.1534/g3.120.401847

Cai, H., Holleufer, A., Simonsen, B., Schneider, J., Lemoine, A., Gad, H. H., Huang, J., Huang, J., Chen, D., Peng, T., Marques, J. T., Hartmann, R., Martins, N. E. & Imler, J. L. (2020). 2'3'-cGAMP triggers a STING- and NF-κB-dependent broad antiviral response in Drosophila. Science Signaling, 13(660), [eabc4537]. https://doi.org/10.1126/scisignal.abc4537

Holt-Danborg, L., Skovbjerg, S., Goderum, K. W., Nonboe, A. W., Stankevic, E., Frost, Á. K., Vitved, L., Jensen, J. K. & Vogel, L. K. (2020). Insights into the regulation of the matriptase-prostasin proteolytic system. The Biochemical journal, 477(22), 4349-4365. https://doi.org/10.1042/BCJ20200630

Okholm, T. L. H., Sathe, S., Park, S. S., Kamstrup, A. B., Rasmussen, A. M., Shankar, A., Chua, Z. M., Fristrup, N., Nielsen, M. M., Vang, S., Dyrskjøt, L., Aigner, S., Damgaard, C. K., Yeo, G. W. & Pedersen, J. S. (2020). Transcriptome-wide profiles of circular RNA and RNA-binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression. Genome Medicine, 12(112), [112]. https://doi.org/10.1186/s13073-020-00812-8

Malinowska, M., Nagy, I., Wagemaker, C. A. M., Ruud, A. K., Svane, S. F., Thorup-Kristensen, K., Jensen, C. S., Eriksen, B., Krusell, L., Jahoor, A., Jensen, J., Eriksen, L. B. & Asp, T. (2020). The cytosine methylation landscape of spring barley revealed by a new reduced representation bisulfite sequencing pipeline, WellMeth. The Plant Genome, 13(3), e20049. https://doi.org/10.1002/tpg2.20049

Harwood, S. L., Nielsen, N. S., Jensen, K. T., Nielsen, P. K., Thøgersen, I. & Enghild, J. J. (2020). α₂-Macroglobulin-like protein 1 can conjugate and inhibitproteases through their hydroxyl groups, because of anenhanced reactivity of its thiol ester. Journal of Biological Chemistry, 295(49), 16732-16742. https://doi.org/10.1074/jbc.RA120.015694

Manav, M. C., Van, L. B., Lin, J., Fuglsang, A., Peng, X. & Brodersen, D. E. (2020). Structural basis for inhibition of an archaeal CRISPR-Cas type I-D large subunit by an anti-CRISPR protein. Nature Communications, 11(1), [5993]. https://doi.org/10.1038/s41467-020-19847-x

Dalskov, L., Narita, R., Andersen, L. L., Jensen, N., Assil, S., Kristensen, K. H., Mikkelsen, J. G., Fujita, T., Mogensen, T. H., Paludan, S. R. & Hartmann, R. (2020). Characterization of distinct molecular interactions responsible for IRF₃ and IRF₇ phosphorylation and subsequent dimerization. Nucleic Acids Research, 48(20), 11421-11433. https://doi.org/10.1093/nar/gkaa873

Rajewsky, N., Almouzni, G., Gorski, S. A., Aerts, S., Amit, I., Bertero, M. G., Bock, C., Bredenoord, A. L., Cavalli, G., Chiocca, S., Clevers, H., De Strooper, B., Eggert, A., Ellenberg, J., Fernández, X. M., Figlerowicz, M., Gasser, S. M., Hubner, N., Kjems, J. ... LifeTime Community Working Groups (2020). LifeTime and improving European healthcare through cell-based interceptive medicine. Nature, 587, 377-386. https://doi.org/10.1038/s41586-020-2715-9

Lin, J., Frank, M. & Reid, D. (2020). No Home without Hormones: How Plant Hormones Control Legume Nodule Organogenesis. Plant Communications, 1(5), [100104]. https://doi.org/10.1016/j.xplc.2020.100104

Küssau, T., Van Wyk, N., Johansen, M. D., Alsarraf, H. M. A. B., Neyret, A., Hamela, C., Sørensen, K. K., Thygesen, M. B., Beauvineau, C., Kremer, L. & Blaise, M. (2020). Functional Characterization of the N-Acetylmuramyl-l-Alanine Amidase, Ami1, from Mycobacterium abscessus. Cells, 9(11), [2410]. https://doi.org/10.3390/cells9112410

Stoll, L., Rodríguez-Trejo, A., Guay, C., Brozzi, F., Bayazit, M. B., Gattesco, S., Menoud, V., Sobel, J., Marques, A. C., Venø, M. T., Esguerra, J. L. S., Barghouth, M., Suleiman, M., Marselli, L., Kjems, J., Eliasson, L., Renström, E., Bouzakri, K., Pinget, M. ... Regazzi, R. (2020). A circular RNA generated from an intron of the insulin gene controls insulin secretion. Nature Communications, 11, [5611]. https://doi.org/10.1038/s41467-020-19381-w

Hollensen, A. K., Thomsen, H. S., Lloret-Llinares, M., Kamstrup, A. B., Jensen, J. M., Luckmann, M., Birkmose, N., Palmfeldt, J., Jensen, T. H., Hansen, T. B. & Damgaard, C. K. (2020). circZNF827 nucleates a transcription inhibitory complex to balance neuronal differentiation. eLife, 9, [e58478]. https://doi.org/10.7554/eLife.58478

Fields, B., Moeskjaer, S., Friman, V-P., Andersen, S. U. & Young, J. P. W. (2020). MAUI-seq: Metabarcoding using amplicons with unique molecular identifiers to improve error correction. Molecular Ecology Resources. https://doi.org/10.1111/1755-0998.13294

Moesgaard, L., Petersen, D., Szomek, M., Reinholdt, P., Winkler, M., Frain, K. M., Müller, P., Pedersen, B. P., Kongsted, J. & Wüstner, D. (2020). Mechanistic Insight into Lipid Binding to Yeast Niemann Pick Type C2 Protein. Biochemistry, 59(45), 4407–4420. https://doi.org/10.1021/acs.biochem.0c00574

Peltonen, J., Tuomainen, K., Sallinen, T., Faress, I., Suleymanova, I., Al-Samadi, A., Salo, T. & Åström, P. (2020). Effect of sex steroid hormones on tongue cancer cells in vitro. Anticancer Research, 40(11), 6029-6037. https://doi.org/10.21873/anticanres.14624

Poulsen, E. T., Lumi, X., Hansen, A. K., Enghild, J. J. & Petrovski, G. (2020). Protein Composition of the Subretinal Fluid Suggests Selective Diffusion of Vitreous Proteins in Retinal Detachment. Translational vision science & technology, 9(11), 16. https://doi.org/10.1167/tvst.9.11.16

Conrad, T., Ntini, E., Lang, B., Cozzuto, L., Andersen, J. B., Marquardt, J. U., Ponomarenko, J., Tartaglia, G. G. & Ørom, U. A. V. (2020). Determination of primary microRNA processing in clinical samples by targeted pri-miR-sequencing. RNA, 26(11), 1726-1730. https://doi.org/10.1261/rna.076240.120

Frank, M., Cortleven, A., Novák, O. & Schmülling, T. (2020). Root-derived trans-zeatin cytokinin protects Arabidopsis plants against photoperiod stress. Plant Cell and Environment, 43(11), 2637-2649. https://doi.org/10.1111/pce.13860

Gonçalves, N. P., Yan, Y., Ulrichsen, M., Venø, M. T., Poulsen, E. T., Enghild, J. J., Kjems, J. & Vægter, C. B. (2020). Modulation of Small RNA Signatures in Schwann-Cell-Derived Extracellular Vesicles by the p75 Neurotrophin Receptor and Sortilin. Biomedicines, 8(11), [450]. https://doi.org/10.3390/biomedicines8110450

Dalskov, L., Møhlenberg, M., Thyrsted, J., Blay-Cadanet, J., Poulsen, E. T., Folkersen, B. H., Skaarup, S. H., Olagnier, D., Reinert, L., Enghild, J. J., Hoffmann, H. J., Holm, C. K. & Hartmann, R. (2020). SARS-CoV-2 evades immune detection in alveolar macrophages. EMBO Reports, 21(12), [e51252]. https://doi.org/10.15252/embr.202051252

Dou, Y., Barbosa, I., Jiang, H., Iasillo, C., Molloy, K. R., Schulze, W. M., Cusack, S., Schmid, M., Le Hir, H., LaCava, J. & Jensen, T. H. (2020). NCBP3 positively impacts mRNA biogenesis. Nucleic Acids Research, 48(18), 10413-10427. https://doi.org/10.1093/nar/gkaa744

Dou, Y., Kalmykova, S., Pashkova, M., Oghbaie, M., Jiang, H., Molloy, K. R., Chait, B. T., Rout, M. P., Fenyö, D., Jensen, T. H., Altukhov, I. & LaCava, J. (2020). Affinity proteomic dissection of the human nuclear cap-binding complex interactome. Nucleic Acids Research, 48(18), 10456-10469. https://doi.org/10.1093/nar/gkaa743

Christensen, B., Toth, A. E., Nielsen, S. S. E., Scavenius, C., Petersen, S. V., Enghild, J. J., Rasmussen, J. T., Nielsen, M. S. & Sørensen, E. S. (2020). Transport of a peptide from bovine α_s1-casein across models of the intestinal and blood–brain barriers. Nutrients, 12(10), [3157]. https://doi.org/10.3390/nu12103157

Seidenbecher, S. E., Sanders, J. I., von Philipsborn, A. C. & Kvitsiani, D. (2020). Reward foraging task and model-based analysis reveal how fruit flies learn value of available options. PLOS ONE, 15(10 October), [e0239616]. https://doi.org/10.1371/journal.pone.0239616

Dasari, J. B., Soren, B. C., Ottaviani, A., Tesauro, C., Marino, S., Messina, B. & Fiorani, P. (2020). Swapping of The N-Terminal Domain of Human Topoisomerase 1B with the Corresponding Plasmodium Falciparum Counterpart Strongly Impairs Enzyme Activity. Reports of Biochemistry and Molecular Biology, 8(4), 366-375. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275839/

Yan, Y., Chang, C., Su, J., Venø, M. T. & Kjems, J. (2020). Osteoblastogenesis Alters Small RNA Profiles in EVs Derived from Bone Marrow Stem Cells (BMSCs) and Adipose Stem Cells (ASCs). Biomedicines, 8(10), [387]. https://doi.org/10.3390/biomedicines8100387

Lukassen, M. V., Poulsen, E. T., Donaghy, J., Mogensen, E. H., Christie, K. A., Roshanravan, H., DeDioniso, L., Nesbit, M. A., Moore, T. & Enghild, J. J. (2020). Protein Analysis of the TGFBI^R124H Mouse Model Gives Insight into Phenotype Development of Granular Corneal Dystrophy. Proteomics - Clinical Applications, 14(6), [1900072]. https://doi.org/10.1002/prca.201900072

Sweet, M. E., Zhang, X., Erdjument-Bromage, H., Dubey, V., Khandelia, H., Neubert, T. A., Pedersen, B. P. & Stokes, D. L. (2020). Serine phosphorylation regulates the P-type potassium pump KdpFABC. eLife, 9, [e55480]. https://doi.org/10.7554/eLife.55480

Zhang, J., Song, L., Pedersen, D. V., Li, A., Lambris, J. D., Andersen, G. R., Mollnes, T. E., Ma, Y. J. & Garred, P. (2020). Soluble collectin-12 mediates C3-independent docking of properdin that activates the alternative pathway of complement. eLife, 9. https://doi.org/10.7554/eLife.60908

Bodó, K., Hayashi, Y., Gerencsér, G., László, Z., Kéri, A., Galbács, G., Telek, E., Mészáros, M., Deli, M. A., Kokhanyuk, B., Németh, P. & Engelmann, P. (2020). Species-specific sensitivity of Eisenia earthworms towards noble metal nanoparticles: a multiparametric in vitro study. Environmental Science: Nano, 7(11), 3509-3525. https://doi.org/10.1039/c9en01405e

Zhang, B., Nandakumar, R., Reinert, L. S., Huang, J., Laustsen, A., Gao, Z., Sun, C., Jensen, S. B., Troldborg, A., Assil, S., Berthelsen, M. F., Scavenius, C., Zhang, Y., Windross, S. J., Olagnier, D., Prabakaran, T., Bodda, C., Narita, R., Cai, Y. ... Paludan, S. R. (2020). Author Correction: STEEP mediates STING ER exit and activation of signaling (Nature Immunology, (2020), 21, 8, (868-879), 10.1038/s41590-020-0730-5). Nature Immunology, 21(11), 1468-1469. https://doi.org/10.1038/s41590-020-0803-5

Bodó, K., Baranzini, N., Girardello, R., Kokhanyuk, B., Németh, P., Hayashi, Y., Grimaldi, A. & Engelmann, P. (2020). Nanomaterials and Annelid Immunity: A Comparative Survey to Reveal the Common Stress and Defense Responses of Two Sentinel Species to Nanomaterials in the Environment. Biology, 9(10), [307]. https://doi.org/10.3390/biology9100307

Hjortebjerg, R., Espelund, U., Rasmussen, T. R., Folkersen, B., Steiniche, T., Georgsen, J. B., Oxvig, C. & Frystyk, J. (2020). Pregnancy-Associated Plasma Protein-A2 Is Associated With Mortality in Patients With Lung Cancer. Frontiers in Endocrinology, 11, [614]. https://doi.org/10.3389/fendo.2020.00614

Rossnerova , A., Izzotti , A., Pulliero , A., Bast, A., Rattan, S. & Rossner , P. (2020). The Molecular Mechanisms of Adaptive Response Related to Environmental Stress. International Journal of Molecular Sciences , 21(19), [7053]. https://doi.org/10.3390/ijms21197053

Pedersen, H., Jensen, R. K., Jensen, J. M. B., Fox, R., Pedersen, D. V., Olesen, H. G., Hansen, A. G., Christiansen, D., Mazarakis, S. M. M., Lojek, N., Hansen, P., Gadeberg, T. A. F., Zarantonello, A., Laursen, N. S., Mollnes, T. E., Johnson, M. B., Stevens, B., Thiel, S. & Andersen, G. R. (2020). A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity. Journal of Immunology, 205(8). https://doi.org/10.4049/jimmunol.2000752

Troldborg, A., Halkjær, L., Pedersen, H., Hansen, A., Loft, A. G., Lindegaard, H., Stengaard-Pedersen, K., Graversen, J. H., Palarasah, Y. & Thiel, S. (2020). Complement activation in human autoimmune diseases and mouse models; employing a sandwich immunoassay specific for C3dg. Journal of Immunological Methods, 486, [112866]. https://doi.org/10.1016/j.jim.2020.112866

Kristensen, L. S., Ebbesen, K. K., Sokol, M., Jakobsen, T., Korsgaard, U., Eriksen, A. C., Hansen, T. B., Kjems, J. & Hager, H. (2020). Spatial expression analyses of the putative oncogene ciRS-7 in cancer reshape the microRNA sponge theory. Nature Communications, 11, [4551]. https://doi.org/10.1038/s41467-020-18355-2

Wu, M., Karadoulama, E., Lloret-Llinares, M., Rouviere, J. O., Vaagensø, C. S., Moravec, M., Li, B., Wang, J., Wu, G., Gockert, M., Pelechano, V., Jensen, T. H. & Sandelin, A. (2020). The RNA exosome shapes the expression of key protein-coding genes. Nucleic Acids Research, 48(15), 8509-8528. https://doi.org/10.1093/nar/gkaa594

Ferguson, S., Major, A. S., Sullivan, J. T., Bourke, S. D., Kelly, S. J., Perry, B. J. & Ronson, C. W. (2020). Rhizobium leguminosarum bv. trifolii NodD2 Enhances Competitive Nodule Colonization in the Clover-Rhizobium Symbiosis. Applied and Environmental Microbiology, 86(18). https://doi.org/10.1128/AEM.01268-20

Aminzadeh, A., Tiwari, M. K., Mamah Mustapha, S. S., Navarrete, S. J., Henriksen, A. B., Møller, I. M., Krogfelt, K. A., Bjerrum, M. J. & Jørgensen, R. (2020). Detoxification of toxin A and toxin B by copper ion-catalyzed oxidation in production of a toxoid-based vaccine against Clostridioides difficile. Free Radical Biology and Medicine, 160, 433-446. https://doi.org/10.1016/j.freeradbiomed.2020.08.021

Mohammad-Beigi, H., Hayashi, Y., Zeuthen, C. M., Eskandari, H., Scavenius, C., Juul-Madsen, K., Vorup-Jensen, T., Enghild, J. J. & Sutherland, D. S. (2020). Mapping and identification of soft corona proteins at nanoparticles and their impact on cellular association. Nature Communications, 11, [4535]. https://doi.org/10.1038/s41467-020-18237-7

Møller, I. M., Rao, R. S. P., Jiang, Y., Thelen, J. J. & Xu, D. (2020). Proteomic and Bioinformatic Profiling of Transporters in Higher Plant Mitochondria. Biomolecules, 10(8), [1190]. https://doi.org/10.3390/biom10081190

Darvishi, N., Rahimi, K., Mansouri, K., Fathi, F., Menbari, M. N., Mohammadi, G. & Abdi, M. (2020). MiR-646 prevents proliferation and progression of human breast cancer cell lines by suppressing HDAC2 expression. Molecular and Cellular Probes, 53, [101649]. https://doi.org/10.1016/j.mcp.2020.101649

Ørom, U. A. V. (2020). Preface. Methods in Molecular Biology, 2161, v.

Wong, J. E. M. M. & Blaise, M. (2020). Report of false positives when using zymography to assess peptidoglycan hydrolytic activity of an endopeptidase with multiple LysM domains. Biochimie, 177, 25-29. https://doi.org/10.1016/j.biochi.2020.07.014

Dyla, M. & Kjaergaard, M. (2020). Intrinsically disordered linkers control tethered kinases via effective concentration. Proceedings of the National Academy of Sciences of the United States of America, 117(35). https://doi.org/10.1073/pnas.2006382117

Schytte, G. N., Christensen, B. S., Bregenov, I. & Sørensen, E. S. (2020). Ras-transformation reduce FAM20C expression and osteopontin phosphorylation. Bioscience Reports, 40(9), [BSR20194378]. https://doi.org/10.1042/BSR20194378

Christensen, B., Schytte, G. N., Scavenius, C., Enghild, J. J., McKee, M. D. & Sørensen, E. S. (2020). FAM20C-Mediated Phosphorylation of MEPE and Its Acidic Serine- and Aspartate-Rich Motif. JBMR Plus, 4(8), [e10378]. https://doi.org/10.1002/jbm4.10378

Bozsoki, Z., Gysel, K., Hansen, S. B., Lironi, D., Krönauer, C., Feng, F., de Jong, N., Vinther, M., Kamble, M., Thygesen, M. B., Engholm, E., Kofoed, C., Fort, S., Sullivan, J. T., Ronson, C. W., Jensen, K. J., Blaise, M., Oldroyd, G., Stougaard, J. ... Radutoiu, S. (2020). Ligand-recognizing motifs in plant LysM receptors are major determinants of specificity. Science (New York, N.Y.), 369(6504), 663-670. https://doi.org/10.1126/science.abb3377

Mamsen, L. S., Aikaterini, Z., Bøtkjær, J. A., Hardlei, J. R., Ernst, E., Oxvig, C., Fowler, P. A. & Andersen, C. Y. (2020). Expression of the Insulin-like Growth Factor System in First- and Second-Trimester Human Embryonic and Fetal Gonads. The Journal of clinical endocrinology and metabolism, 105(9), [dgaa470]. https://doi.org/10.1210/clinem/dgaa470

Ntini, E. & Vang Ørom, U. A. (2020). Targeting Polyadenylation for Retention of RNA at Chromatin. Methods in molecular biology (Clifton, N.J.), 2161, 51-58. https://doi.org/10.1007/978-1-0716-0680-3_5

Chen, M., Maimaitili, M., Habekost, M., Gill, K. P., Mermet-Joret, N., Nabavi, S., Febbraro, F. & Denham, M. (2020). Rapid generation of regionally specified CNS neurons by sequential patterning and conversion of human induced pluripotent stem cells. Stem Cell Research, 48, [101945]. https://doi.org/10.1016/j.scr.2020.101945

Mohammad-Beigi, H., Scavenius, C., Jensen, P. B., Kjaer-Sorensen, K., Oxvig, C., Boesen, T., Enghild, J. J., Sutherland, D. S. & Hayashi, Y. (2020). Tracing the In Vivo Fate of Nanoparticles with a "Non-Self" Biological Identity. ACS Nano, 14(8), 10666-10679. https://doi.org/10.1101/2020.03.27.012146, https://doi.org/10.1021/acsnano.0c05178

Zarantonello, A., Presumey, J., Simoni, L., Yalcin, E., Fox, R., Hansen, A., Olesen, H. G., Thiel, S., Johnson, M. B., Stevens, B., Laursen, N. S., Carroll, M. C. & Andersen, G. R. (2020). An Ultrahigh-Affinity Complement C4b-Specific Nanobody Inhibits In Vivo Assembly of the Classical Pathway Proconvertase. Journal of Immunology, 205(6), 1678-1694. https://doi.org/10.4049/jimmunol.2000528

Barra, J., Gaidos, G. S., Blumenthal, E., Beckedorff, F., Tayar, M. M., Kirstein, N., Karakac, T. K., Jensen, T. H., Impens, F., Gevaert, K., Leucci, E., Shiekhattar, R. & Marine, J. C. (2020). Integrator restrains paraspeckles assembly by promoting isoform switching of the lncRNA NEAT1. Science Advances, 6(27), [eaaz9072]. https://doi.org/10.1126/sciadv.aaz9072

Hansen, M. S., Gadegaard, I. S. E., Christensen, E. A., Blans, K. I. M., Nejsum, L. N. & Rasmussen, J. T. (2020). Specific and Non-Invasive Fluorescent Labelling of Extracellular Vesicles for Evaluation of Intracellular Processing by Intestinal Epithelial Cells. Biomedicines, 8(7), [211]. https://doi.org/10.3390/biomedicines8070211

Kirkegaard, K., Yan, Y., Sørensen, B. S., Hardason, T., Hanson, C., Ingerslev, H. J., Knudsen, U. B., Kjems, J., Lundin, K. & Ahlström, A. (2020). Comprehensive analysis of soluble RNAs in human embryo culture media and blastocoel fluid. Journal of Assisted Reproduction and Genetics, 37(9), 2199–2209. https://doi.org/10.1007/s10815-020-01891-7

Wong, J. E. M. M., Gysel, K., Birkefeldt, T. G., Vinther, M., Muszyński, A., Azadi, P., Laursen, N. S., Sullivan, J. T., Ronson, C. W., Stougaard, J. & Andersen, K. R. (2020). Structural signatures in EPR3 define a unique class of plant carbohydrate receptors. Nature Communications, 11, [3797]. https://doi.org/10.1038/s41467-020-17568-9

Venø, M. T., Reschke, C. R., Morris, G., Connolly, N. M. C., Su, J., Yan, Y., Engel, T., Jimenez-Mateos, E. M., Harder, L. M., Pultz, D., Haunsberger, S. J., Pal, A., Heller, J. P., Campbell, A., Langa, E., Brennan, G. P., Conboy, K., Richardson, A., Norwood, B. A. ... Henshall, D. C. (2020). A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy. Proceedings of the National Academy of Sciences of the United States of America, 117(27), 15977-15988. https://doi.org/10.1073/pnas.1919313117

Melko, M., Winczura, K., Rouvière, J. O., Oborská-Oplová, M., Andersen, P. K. & Heick Jensen, T. (2020). Mapping domains of ARS2 critical for its RNA decay capacity. Nucleic Acids Research, 48(12), 6943-6953. https://doi.org/10.1093/nar/gkaa445

Laursen, N. S., Pedersen, D. V., Gytz, H., Zarantonello, A., Bernth Jensen, J. M., Hansen, A. G., Thiel, S. & Andersen, G. R. (2020). Functional and Structural Characterization of a Potent C1q Inhibitor Targeting the Classical Pathway of the Complement System. Frontiers in Immunology, 11, [1504]. https://doi.org/10.3389/fimmu.2020.01504

Yoshimoto, R., Rahimi, K., Hansen, T. B., Kjems, J. & Mayeda, A. (2020). Biosynthesis of Circular RNA ciRS-7/CDR1as Is Mediated by Mammalian-wide Interspersed Repeats. iScience, 23(7), [101345]. https://doi.org/10.1016/j.isci.2020.101345

Jensen, G. V., Pedersen, J. N., Otzen, D. E. & Pedersen, J. S. (2020). Multi-Step Unfolding and Rearrangement of α-Lactalbumin by SDS Revealed by Stopped-Flow SAXS. Frontiers in Molecular Biosciences, 7, [125]. https://doi.org/10.3389/fmolb.2020.00125

Pedersen, J. N., Frislev, H. K. S., Pedersen, J. S. & Otzen, D. (2020). Structures and mechanisms of formation of liprotides. B B A - Proteins and Proteomics, 1868(11), [140505]. https://doi.org/10.1016/j.bbapap.2020.140505

Tausen, M., Clausen, M. M., Moeskjær, S., Shihavuddin, ASM., Dahl, A. B., Janss, L. & Andersen, S. U. (2020). Greenotyper: Image-based plant phenotyping using distributed computing and deep learning. Frontiers in Plant Science, 11, [1181]. https://doi.org/10.3389/fpls.2020.01181

Lazarov, E., Hillebrand, M., Schröder, S., Ternka, K., Hofhuis, J., Ohlenbusch, A., Barrantes-Freer, A., Pardo, L. A., Fruergaard, M. U., Nissen, P., Brockmann, K., Gärtner, J. & Rosewich, H. (2020). Comparative analysis of alternating hemiplegia of childhood and rapid-onset dystonia-parkinsonism ATP1A3 mutations reveals functional deficits, which do not correlate with disease severity. Neurobiology of Disease, 143, [105012]. https://doi.org/10.1016/j.nbd.2020.105012

Dear, A. J., Meisl, G., Saric, A., Michaels, T. C. T., Kjaergaard, M., Linse, S. & Knowles, T. P. J. (2020). Identification of on- and off-pathway oligomers in amyloid fibril formation. Chemical Science, 11(24), 6236-6247. https://doi.org/10.1039/c9sc06501f

Wang, D., Yang, Y., Wang, Y., Proulle, V., Andreasen, P. A., Hong, W., Chen, Z., Huang, M. & Xu, P. (2020). Embelin ameliorated sepsis-induced disseminated intravascular coagulation intensities by simultaneously suppressing inflammation and thrombosis. Biomedicine and Pharmacotherapy, 130, [110528]. https://doi.org/10.1016/j.biopha.2020.110528

Zhang, B. C., Nandakumar, R., Reinert, L. S., Huang, J., Laustsen, A., Gao, Z. L., Sun, C. L., Jensen, S. B., Troldborg, A., Assil, S., Berthelsen, M. F., Scavenius, C., Zhang, Y., Windross, S. J., Olagnier, D., Prabakaran, T., Bodda, C., Narita, R., Cai, Y. ... Paludan, S. R. (2020). STEEP mediates STING ER exit and activation of signaling. Nature Immunology, 21(8), 868-879. https://doi.org/10.1038/s41590-020-0730-5

He, J., Becares, E. R., Thulstrup, P. W., Gamon, L. F., Pedersen, J. N., Otzen, D., Gourdon, P., Davies, M. J. & Hägglund, P. (2020). Peroxynitrous acid (ONOOH) modifies the structure of anastellin and influences its capacity to polymerize fibronectin. Redox Biology, 36, [101631]. https://doi.org/10.1016/j.redox.2020.101631

Kamal, N., Mun, T., Reid, D., Lin, J-S., Akyol, T. Y., Sandal, N., Asp, T., Hirakawa, H., Stougaard, J., Mayer, K. F. X., Sato, S. & Andersen, S. U. (2020). Insights into the evolution of symbiosis gene copy number and distribution from a chromosome-scale Lotus japonicus Gifu genome sequence. D N A Research, 27(3), [dsaa015]. https://doi.org/10.1093/dnares/dsaa015

Major, J., Crotta, S., Llorian, M., McCabe, T. M., Gad, H. H., Priestnall, S. L., Hartmann, R. & Wack, A. (2020). Type I and III interferons disrupt lung epithelial repair during recovery from viral infection. Science (New York, N.Y.), 369(6504), 712-717. https://doi.org/10.1126/science.abc2061

Jørgensen, S. E., Christiansen, M., Høst, C., Glerup, M., Mahler, B., Lausten, M. M., Gad, H. H., Hartmann, R., Herlin, T. & Mogensen, T. H. (2020). Systemic juvenile idiopathic arthritis and recurrent macrophage activation syndrome due to a CASP1 variant causing inflammasome hyperactivation. Rheumatology (Oxford, England), 59(10). https://doi.org/10.1093/rheumatology/keaa242

Felgenhauer, U., Schoen, A., Gad, H. H., Hartmann, R., Schaubmar, A. R., Failing, K., Drosten, C. & Weber, F. (2020). Inhibition of SARS-CoV-2 by type I and type III interferons. The Journal of Biological Chemistry, 295(41). https://doi.org/10.1074/jbc.AC120.013788

Greibe, E., Reitelseder, S., Bechshoeft, R., Bülow, J., Højfeldt, G., Schacht, S. R., Knudsen, M. L., Tetens, I., Ostenfeld, M., Ramer Mikkelsen, U., Würtz Heegaard, C., Nexø, E. & Holm, L. (2020). Effects of prolonged whey protein supplementation and resistance training on biomarkers of vitamin B12 status: A 1-year randomized intervention in healthy older adults (the CALM study). Nutrients, 12(7), [2015]. https://doi.org/10.3390/nu12072015

Ke, P. C., Zhou, R., Serpell, L. C., Riek, R., Knowles, T. P. J., Lashuel, H. A., Gazit, E., Hamley, I. W., Davis, T. P., Fändrich, M., Otzen, D. E., Chapman, M. R., Dobson, C. M., Eisenberg, D. S. & Mezzenga, R. (2020). Half a century of amyloids: past, present and future. Chemical Society Reviews, 49(15), 5473-5509. https://doi.org/10.1039/c9cs00199a

Menbari, M. N., Rahimi, K., Ahmadi, A., Mohammadi-Yeganeh, S., Elyasi, A., Darvishi, N., Hosseini, V. & Abdi, M. (2020). Association of hdac8 expression with pathological findings in triple negative and non-triple negative breast cancer: Implications for diagnosis. Iranian Biomedical Journal, 24(5), 283-289. https://doi.org/10.29252/ibj.24.5.283

Zhang, Z., Wen, K., Zhang, C., Laroche, F., Wang, Z., Zhou, Q., Liu, Z., Abrahams, J. P. & Zhou, X. (2020). Extracellular Nanovesicle Enhanced Gene Transfection Using Polyethyleneimine in HEK293T Cells and Zebrafish Embryos. Frontiers in Bioengineering and Biotechnology, 8, [448]. https://doi.org/10.3389/fbioe.2020.00448

Ahmed, I. M., Nadira, U. A., Qiu, C. W., Cao, F., Chen, Z. H., Vincze, E. & Wu, F. (2020). The Barley S-Adenosylmethionine Synthetase 3 Gene HvSAMS3 Positively Regulates the Tolerance to Combined Drought and Salinity Stress in Tibetan Wild Barley. Cells, 9(6), [1530]. https://doi.org/10.3390/cells9061530

Falkowski, K., Bielecka, E., Thøgersen, I. B., Bocheńska, O., Płaza, K., Kalińska, M., Sąsiadek, L., Magoch, M., Pęcak, A., Wiśniewska, M., Gruba, N., Wysocka, M., Wojtysiak, A., Brzezińska-Bodal, M., Sychowska, K., Pejkovska, A., Rehders, M., Butler, G., Overall, C. M. ... Kantyka, T. (2020). Kallikrein-Related Peptidase 14 Activates Zymogens of Membrane Type Matrix Metalloproteinases (MT-MMPs)-A CleavEx Based Analysis. International Journal of Molecular Sciences, 21(12), [4383]. https://doi.org/10.3390/ijms21124383

Gan, Q. F., Li, Y. R., Liu, Q. H., Lund, M., Su, G. S. & Liang, X. W. (2020). Genome-wide association studies for the concentrations of insulin, triiodothyronine, and thyroxine in Chinese Holstein cattle. Tropical Animal Health and Production, 52(4), 1655-1660. https://doi.org/10.1007/s11250-019-02170-z

Pedersen, D. V., Rösner, T., Hansen, A. G., Andersen, K. R., Thiel, S., Andersen, G. R., Valerius, T. & Laursen, N. S. (2020). Recruitment of properdin by bi-specific nanobodies activates the alternative pathway of complement. Molecular Immunology, 124, 200-210. https://doi.org/10.1016/j.molimm.2020.06.005

Prokunina-Olsson, L., Alphonse, N., Dickenson, R. E., Durbin, J. E., Glenn, J. S., Hartmann, R., Kotenko, S. V., Lazear, H. M., O’Brien, T. R., Odendall, C., Onabajo, O. O., Piontkivska, H., Santer, D. M., Reich, N. C., Wack, A. & Zanoni, I. (2020). COVID-19 and emerging viral infections: The case for interferon lambda. Journal of Experimental Medicine, 217(5), [e20200653]. https://doi.org/10.1084/jem.20200653

Bernth Jensen, J. M., Laursen, N. S., Kjeldsen Jensen, R., Andersen, G. R., Jensenius, J. C., Skov Sørensen, U. B. & Thiel, S. (2020). Complement activation by human IgG antibodies to galactose-α-1,3-galactose. Immunology, 161(1), 66-79. https://doi.org/10.1111/imm.13229

Hejlesen, R. & Füchtbauer, E. M. (2020). Multiple site-directed mutagenesis via simple cloning by prolonged overlap extension. BioTechniques, 68(6), 345-348. https://doi.org/10.2144/btn-2019-0104

Martín-Encinas, E., Conejo-Rodríguez, V., Miguel, J. A., Martínez-Ilarduya, J. M., Rubiales, G., Knudsen, B. R., Palacios, F. & Alonso, C. (2020). Novel phosphine sulphide gold(i) complexes: topoisomerase I inhibitors and antiproliferative agents. Dalton Transactions, 49(23), 7852-7861. https://doi.org/10.1039/d0dt01467b

Ravishankar, H., Pedersen, M. N., Eklund, M., Sitsel, A., Li, C., Duelli, A., Levantino, M., Wulff, M., Barth, A., Olesen, C., Nissen, P. & Andersson, M. (2020). Tracking Ca²⁺ ATPase intermediates in real time by x-ray solution scattering. Science Advances, 6(12), [eaaz0981]. https://doi.org/10.1126/sciadv.aaz0981

Lloyd, K. A., Parsons, B. N., Burkitt, M. D., Moore, A. R., Papoutsopoulou, S., Boyce, M., Duckworth, C. A., Exarchou, K., Howes, N., Rainbow, L., Fang, Y., Oxvig, C., Dodd, S., Varro, A., Hall, N. & Pritchard, D. M. (2020). Netazepide Inhibits Expression of Pappalysin 2 in Type 1 Gastric Neuroendocrine Tumors. Cellular and Molecular Gastroenterology and Hepatology, 10(1), 113-132. https://doi.org/10.1016/j.jcmgh.2020.01.010

Moreno, A. (2020). Molecular mechanisms of forgetting. European Journal of Neuroscience. https://doi.org/10.1111/ejn.14839

Hao, D., Wang, X., Wang, X., Thomsen, B., Kadarmideen, H. N., Lan, X., Huang, Y. & Chen, H. (2020). Transcriptomic changes in bovine skeletal muscle cells after resveratrol treatment. Gene, 754, [144849]. https://doi.org/10.1016/j.gene.2020.144849

Godskesen, L. E., Lassen, T. R., Jespersen, N. R., Siersbæk, M., Yan, Y., Nielsen, M. M., Tjønnfjord, S. K., Grøntved, L., Madsen, G., Kjems, J., Bøtker, H. E., Schmidt, M. R., Krag, A. & Kjeldsen, J. (2020). Remote ischemic conditioning in active ulcerative colitis: An explorative randomized clinical trial. Scientific Reports, 10(1), [9537]. https://doi.org/10.1038/s41598-020-65692-9

Olijhoek, D. W., Difford, G. F., Lund, P. & Løvendahl, P. (2020). Phenotypic modeling of residual feed intake using physical activity and methane production as energy sinks. Journal of Dairy Science, 103(8), 6967-6981. https://doi.org/10.3168/jds.2019-17489

Xiao, H., Shiu, P. K. T., Gabryleska, M., Conn, S. J., Dey, A., Chakrabarti, K., Regouc, M., Pichler, M., Vang Ørom, U. A., Santulli, G., Nishiwada, S., Goel, A., Nagarajan, V., Timmons, L., Alahari, S. K., Laprovitera, N., Ferracin, M., Hu, P. & Jin, H. (2020). The non-coding rna journal club: Highlights on recent papers-7. Non-coding RNA, 5(2), [40]. https://doi.org/10.3390/NCRNA5020040

Gul, A., Hussain, G., Iqbal, A., Rao, A. Q., Din, S. U., Yasmeen, A., Shahid, N., Ahad, A., Latif, A., Azam, S., Samiullah, T. R., Hassan, S., Shahid, A. A. & Husnain, T. (2020). Constitutive expression of Asparaginase in Gossypium hirsutum triggers insecticidal activity against Bemisia tabaci. Scientific Reports, 10(1), [8958]. https://doi.org/10.1038/s41598-020-65249-w

Liu, C., Li, S., Noer, P. R., Kjaer-Sorensen, K., Juhl, A. K., Goldstein, A., Ke, C., Oxvig, C. & Duan, C. (2020). The metalloproteinase papp-aa controls epithelial cell quiescence-proliferation transition. eLife, 9, [e52322]. https://doi.org/10.7554/eLife.52322

Cagnano, G., Vázquez-De-Aldana, B. R., Asp, T., Roulund, N., Jensen, C. S. & Soto-Barajas, M. C. (2020). Determination of loline alkaloids and mycelial biomass in endophyte-infected schedonorus pratensis by near-infrared spectroscopy and chemometrics. Microorganisms, 8(5), [776]. https://doi.org/10.3390/microorganisms8050776

Krauth, N., Khalil, V., Jariwala, M., Mermet-Joret, N., Vestergaard, A. K., Capogna, M. & Nabavi, S. (2020). TRACE: An Unbiased Method to Permanently Tag Transiently Activated Inputs. Frontiers in Cellular Neuroscience, 14, [114]. https://doi.org/10.3389/fncel.2020.00114

McKellar, S. W., Ivanova, I., van Nues, R. W., Cordiner, R. A., Worboys, W., Langford, A., Jensen, T. H. & Granneman, S. (2020). Monitoring protein-RNA interaction dynamics in vivo at high temporal resolution using χCRAC. Journal of Visualized Experiments, 2020(159), [e61027]. https://doi.org/10.3791/61027

Andrzejczak, O. A., Sørensen, C. K., Wang, W-Q., Kovalchuk, S., Hagensen, C. E., Jensen, O. N., Carciofi, M., Hovmøller, M. S., Rogowska-Wrzesinska, A., Møller, I. M. & Hebelstrup, K. (2020). The effect of phytoglobin overexpresseion on the plant proteome during nonhost response of barley (Hordeum vulgare) to wheat powdery mildew (Blumeria graminis f. sp. tritici). Scientific Reports, 10, [9192]. https://doi.org/10.1038/s41598-020-65907-z

Peil, K., Jürgens, H., Luige, J., Kristjuhan, K. & Kristjuhan, A. (2020). Taf14 is required for the stabilization of transcription pre-initiation complex in Saccharomyces cerevisiae. Epigenetics and Chromatin, 13, [24]. https://doi.org/10.1186/s13072-020-00347-7

Lyons, J. A., Timcenko, M., Dieudonné, T., Lenoir, G. & Nissen, P. (2020). P4-ATPases: how an old dog learnt new tricks — structure and mechanism of lipid flippases. Current Opinion in Structural Biology, 63, 65-73. https://doi.org/10.1016/j.sbi.2020.04.001

Tesauro, C., Keller, J. G., Gromova, I., Gromov, P., Frøhlich, R., Erlandsen, J. U., Andersen, A. H., Stougaard, M. & Knudsen, B. R. (2020). Different camptothecin sensitivities in subpopulations of colon cancer cells correlate with expression of different phospho-isoforms of topoisomerase i with different activities. Cancers, 12(5), [1240]. https://doi.org/10.3390/cancers12051240

Skovbjerg, S., Holt-Danborg, L., Nonboe, A. W., Hong, Z., Frost, Á. K., Schar, C. R., Thomas, C. C., Vitved, L., Jensen, J. K. & Vogel, L. K. (2020). Inhibition of an active zymogen protease: the zymogen form of matriptase is regulated by HAI-1 and HAI-2. The Biochemical journal, 477(9), 1779-1794. https://doi.org/10.1042/BCJ20200182

Mortensen, M. R., Skovsgaard, M. B., Märcher, A., Andersen, V. L., Palmfeldt, J., Nielsen, T. B., Tørring, T., Laursen, N. S., Andersen, K. R., Kjems, J. & Gothelf, K. V. (2020). Introduction of an Aldehyde Handle on Nanobodies by Affinity-Guided Labeling. Bioconjugate Chemistry, 31(5), 1295-1300. https://doi.org/10.1021/acs.bioconjchem.0c00151

Franch, O., Gutiérrez-Corbo, C., Domínguez-Asenjo, B., Boesen, T., Jensen, P. B., Nejsum, L. N., Keller, J. G., Nielsen, S. P., Singh, P. R., Jha, R. K., Nagaraja, V., Balaña-Fouce, R., Ho, Y-P., Reguera, R. M. & Knudsen, B. R. (2020). DNA flowerstructure co-localizes with human pathogens in infected macrophages. Nucleic Acids Research, 48(11), 6081-6091. https://doi.org/10.1093/nar/gkaa341

Giesen, J., Füchtbauer, E. M., Füchtbauer, A., Funke, K., Koesling, D. & Russwurm, M. (2020). AMPA Induces NO-Dependent cGMP Signals in Hippocampal and Cortical Neurons via L-Type Voltage-Gated Calcium Channels. Cerebral Cortex, 30(4), 2128-2143. https://doi.org/10.1093/cercor/bhz227

O'Brien, T. R., Thomas, D. L., Jackson, S. S., Prokunina-Olsson, L., Donnelly, R. P. & Hartmann, R. (2020). Weak Induction of Interferon Expression by Severe Acute Respiratory Syndrome Coronavirus-2 Supports Clinical Trials of Interferon-λ to Treat Early Coronavirus Disease 2019. Clinical Infectious Diseases, 71(6), 1410-12. https://doi.org/10.1093/cid/ciaa453

Madej, M., White, J. B. R., Nowakowska, Z., Rawson, S., Scavenius, C., Enghild, J. J., Bereta, G. P., Pothula, K., Kleinekathoefer, U., Basle, A., Ranson, N. A., Potempa, J. & van den Berg, B. (2020). Structural and functional insights into oligopeptide acquisition by the RagAB transporter from Porphyromonas gingivalis. Nature Microbiology, 5(8), 1016-1025. https://doi.org/10.1038/s41564-020-0716-y

Vilstrup, J., Simonsen, A., Birkefeldt, T., Strandbygård, D., Lyngsø, J., Pedersen, J. S. & Thirup, S. (2020). Crystal and solution structures of fragments of the human leucocyte common antigen-related protein. Acta crystallographica Section D: Structural biology , 76, 406-417. https://doi.org/10.1107/S2059798320003885

Jørgensen, M. L., Müller, C. A., Nøddesbo, M. S. K., Nadzieja, M., Zhang, Z., Su, Y., Just, J., Spindler, K-L. G. & Chen, M. (2020). A Melt-electrowritten Filter for Capture and Culture of Circulating Colon Cancer Cells. Materials Today Bio, 6, [100052]. https://doi.org/10.1016/j.mtbio.2020.100052

Hao, D., Thomsen, B., Bai, J., Peng, S., Lan, X., Huang, Y., Wang, X. & Chen, H. (2020). Expression profiles of the MXD3 gene and association of sequence variants with growth traits in Xianan and Qinchuan cattle. Veterinary Medicine and Science, 6(3), 399-409. https://doi.org/10.1002/vms3.251

Vitre, B., Taulet, N., Guesdon, A., Douanier, A., Dosdane, A., Cisneros, M., Maurin, J., Hettinger, S., Anguille, C., Taschner, M., Lorentzen, E. & Delaval, B. (2020). IFT proteins interact with HSET to promote supernumerary centrosome clustering in mitosis. EMBO Reports, 21(6), [e49234]. https://doi.org/10.15252/embr.201949234

Wang, J., Taschner, M., Petriman, N. A., Andersen, M. B., Basquin, J., Bhogaraju, S., Vetter, M., Wachter, S., Lorentzen, A. & Lorentzen, E. (2020). Purification and crystal structure of human ODA16: Implications for ciliary import of outer dynein arms by the intraflagellar transport machinery. Protein Science, 29(6), 1502-1510. https://doi.org/10.1002/pro.3864

Zhang, Q., Difford, G., Sahana, G., Løvendahl, P., Lassen, J., Lund, M. S., Guldbrandtsen, B. & Janss, L. (2020). Bayesian modeling reveals host genetics associated with rumen microbiota jointly influence methane emission in dairy cows. The ISME Journal, 14(8), 2019-2033. https://doi.org/10.1038/s41396-020-0663-x

Pedersen, H., Jensen, R. K., Hansen, A. G., Gadeberg, T. A. F., Thiel, S., Laursen, N. S. & Andersen, G. (2020). A C3 specific nanobody that blocks all three activation pathways in the human and murine complement system. The Journal of Biological Chemistry, 295(26), 8746-8758. https://doi.org/10.1074/jbc.RA119.012339

van Gils, J. H. M., van Dijk, E., Peduzzo, A., Hofmann, A., Vettore, N., Schützmann, M. P., Groth, G., Mouhib, H., Otzen, D. E., Buell, A. K. & Abeln, S. (2020). The hydrophobic effect characterises the thermodynamic signature of amyloid fibril growth. PLOS Computational Biology, 16(5), [e1007767]. https://doi.org/10.1371/journal.pcbi.1007767

Hobisch, M., van Schie, M. M. C. H., Kim, J., Andersen, K. R., Alcalde, M., Kourist, R., Park, C. B., Hollmann, F. & Kara, S. (2020). Solvent‐Free Photobiocatalytic Hydroxylation of Cyclohexane. ChemCatChem, 12(16), 4009-4013. https://doi.org/10.1002/cctc.202000512

Schytte, G. N., Christensen, B., Bregenov, I., Kjøge, K., Scavenius, C., Petersen, S. V., Enghild, J. J. & Sørensen, E. S. (2020). FAM20C phosphorylation of the RGDSVVYGLR motif in osteopontin inhibits interaction with the αvβ3 integrin. Journal of Cellular Biochemistry, 121(12), 4809-4818. https://doi.org/10.1002/jcb.29708

Briggs, D. C., Langford-Smith, A. W. W., Birchenough, H. L., Jowitt, T. A., Kielty, C. M., Enghild, J. J., Baldock, C., Milner, C. M. & Day, A. J. (2020). Inter-α-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation. The Journal of Biological Chemistry, 295(16), 5278-5291. https://doi.org/10.1074/jbc.RA119.011916, https://doi.org/10.1074/jbc.RA119.011916

Munksgaard, L., Weisbjerg, M. R., Henriksen, J. C. S. & Løvendahl, P. (2020). Changes to steps, lying, and eating behavior during lactation in Jersey and Holstein cows and the relationship to feed intake, yield, and weight. Journal of Dairy Science, 103(5), 4643-4653. https://doi.org/10.3168/jds.2019-17565

Hansen, S. F., Nielsen, S. D-H., Rasmussen, J. T., Larsen, L. B. & Wiking, L. (2020). Disulfide bond formation is not crucial for the heat-induced interaction between β-lactoglobulin and milk fat globule membrane proteins. Journal of Dairy Science, 103(7), 5874-5881. https://doi.org/10.3168/jds.2019-18066

Hao, D., Wang, X., Thomsen, B., Kadarmideen, H. N., Wang, X., Lan, X., Huang, Y., Qi, X. & Chen, H. (2020). Copy number variations and expression levels of guanylate-binding protein 6 gene associated with growth traits of Chinese cattle. Animals, 10(4), [566]. https://doi.org/10.3390/ani10040566

Vogt, L. M., Kwasniewicz, E., Talens, S., Scavenius, C., Bielecka, E., Ekdahl, K. N., Enghild, J. J., Mörgelin, M., Saxne, T., Potempa, J. & Blom, A. M. (2020). Apolipoprotein E Triggers Complement Activation in Joint Synovial Fluid of Rheumatoid Arthritis Patients by Binding C1q. Journal of Immunology, 204(10), 2779-2790. https://doi.org/10.4049/jimmunol.1900372

Sharma, S., Holme, I. B., Dionisio, G., Kodama, M., Dzhanfezova, T., Joernsgaard, B. & Brinch-Pedersen, H. (2020). Cyanidin based anthocyanin biosynthesis in orange carrot is restored by expression of AmRosea1 and AmDelila, MYB and bHLH transcription factors. Plant Molecular Biology, 103, 443-456. https://doi.org/10.1007/s11103-020-01002-1

Petersen, G., Anderson, B., Braun, H. P., Meyer, E. H. & Møller, I. M. (2020). Mitochondria in parasitic plants. Mitochondrion, 52, 173-182. https://doi.org/10.1016/j.mito.2020.03.008

Martín-Encinas, E., Selas, A., Tesauro, C., Rubiales, G., Knudsen, B. R., Palacios, F. & Alonso, C. (2020). Synthesis of novel hybrid quinolino[4,3-b][1,5]naphthyridines and quinolino[4,3-b][1,5]naphthyridin-6(5H)-one derivatives and biological evaluation as topoisomerase I inhibitors and antiproliferatives. European Journal of Medicinal Chemistry, 195, [112292]. https://doi.org/10.1016/j.ejmech.2020.112292

Just, J., Yan, Y., Farup, J., Sieljacks, P., Sloth, M., Venø, M., Gu, T., de Paoli, F. V., Nyengaard, J. R., Bæk, R., Jørgensen, M. M., Kjems, J., Vissing, K. & Drasbek, K. R. (2020). Blood flow-restricted resistance exercise alters the surface profile, miRNA cargo and functional impact of circulating extracellular vesicles. Scientific Reports, 10(1), [5835]. https://doi.org/10.1038/s41598-020-62456-3

Halkjær, L., Troldborg, A., Pedersen, H., Jensen, L., Hansen, A. G., Krarup Hansen, T., Bjerre, M., Østergaard, J. A. & Thiel, S. (2020). Complement Receptor 2 Based Immunoassay Measuring Activation of the Complement System at C3-level in Plasma Samples from Mice and Humans. Frontiers in Immunology, 11, [774]. https://doi.org/10.3389/fimmu.2020.00774

Marvian, A. T., Aliakbari, F., Mohammad-Beigi, H., Ahmadi, Z. A., Mehrpouyan, S., Lermyte, F., Nasouti, M., Collingwood, J. F., Otzen, D. E. & Morshedi, D. (2020). The status of the terminal regions of α-synuclein in different forms of aggregates during fibrillization. International Journal of Biological Macromolecules, 155, 543-550. https://doi.org/10.1016/j.ijbiomac.2020.03.238

Wang, X., Su, G., Hao, D., Lund, M. S. & Kadarmideen, H. N. (2020). Comparisons of improved genomic predictions generated by different imputation methods for genotyping by sequencing data in livestock populations. Journal of Animal Science and Biotechnology, 11(1), [3]. https://doi.org/10.1186/s40104-019-0407-9

Raz, K., Driller, R., Brück, T., Loll, B. & Major, D. T. (2020). Understanding the role of active site residues in CotB2 catalysis using a cluster model. Beilstein Journal of Organic Chemistry, 16, 50-59. https://doi.org/10.3762/bjoc.16.7

Hansen, B. K., Larsen, C. K., Nielsen, J. T., Svenningsen, E. B., Van, L. B., Jacobsen, K. M., Bjerring, M., Flygaard, R. K., Jenner, L. B., Nejsum, L. N., Brodersen, D. E., Mulder, F. A. A., Tørring, T. & Poulsen, T. B. (2020). Structure and Function of the Bacterial Protein Toxin Phenomycin. Structure, 28(5), 528-539.e9. https://doi.org/10.1016/j.str.2020.03.003

Kerwin, P., Yuan, J. & von Philipsborn, A. C. (2020). Female copulation song is modulated by seminal fluid. Nature Communications, 11(1), 1430. [1430]. https://doi.org/10.1038/s41467-020-15260-6

Hansen, S. F., Petrat-Melin, B., Rasmusen, J. T., Larsen, L. B. & Wiking, L. (2020). Impact of industrial cream heat treatments on the protein composition of the milk fat globule membrane. Journal of Dairy Research, 87(1), 89-93. https://doi.org/10.1017/S0022029919000955

Kashyap, S., Hein, K. Z., Chini, C. C. S., Lika, J., Warner, G. M., Bale, L. K., Torres, V. E., Harris, P. C., Oxvig, C., Conover, C. A. & Chini, E. N. (2020). Metalloproteinase PAPP - A regulation of IGF-1 contributes to polycystic kidney disease pathogenesis. JCI Insight, 5(4), [e135700]. https://doi.org/10.1172/jci.insight.135700

Cavassim, M. I. A., Moeskjær, S., Moslemi, C., Fields, B., Bachmann, A., Vilhjálmsson, B. J., Schierup, M. H., W Young, J. P. & Andersen, S. U. (2020). Symbiosis genes show a unique pattern of introgression and selection within a Rhizobium leguminosarum species complex. Microbial Genomics, 6(4). https://doi.org/10.1099/mgen.0.000351

Garland, W. & Jensen, T. H. (2020). Nuclear sorting of RNA. Wiley Interdisciplinary Reviews: RNA, 11(2), [e1572]. https://doi.org/10.1002/wrna.1572

Das Mahapatra, K., Pasquali, L., Søndergaard, J. N., Lapins, J., Nemeth, I. B., Baltás, E., Kemény, L., Homey, B., Moldovan, L. I., Kjems, J., Kutter, C., Sonkoly, E., Kristensen, L. S. & Pivarcsi, A. (2020). A comprehensive analysis of coding and non-coding transcriptomic changes in cutaneous squamous cell carcinoma. Scientific Reports, 10, [3637]. https://doi.org/10.1038/s41598-020-59660-6

Andrzejczak, O. A., Havelund, J. F., Wang, W. Q., Kovalchuk, S., Hagensen, C. E., Hasler-Sheetal, H., Jensen, O. N., Rogowska-Wrzesinska, A., Møller, I. M. & Hebelstrup, K. H. (2020). The hypoxic proteome and metabolome of barley (Hordeum vulgare L.) with and without phytoglobin priming. International Journal of Molecular Sciences, 21(4), [1546]. https://doi.org/10.3390/ijms21041546

Gotfryd, K., Boesen, T., Mortensen, J. S., Khelashvili, G., Quick, M., Terry, D. S., Missel, J. W., LeVine, M. V., Gourdon, P., Blanchard, S. C., Javitch, J. A., Weinstein, H., Loland, C. J., Nissen, P. & Gether, U. (2020). X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release. Nature Communications, 11(1), [1005]. https://doi.org/10.1038/s41467-020-14735-w

Petriman, N. A. & Lorentzen, E. (2020). Moving proteins along in the cilium. eLife, 9. https://doi.org/10.7554/eLife.55254

Zhou, H., Møhlenberg, M., Terczyńska-Dyla, E., Winther, K. G., Hansen, N. H., Vad-Nielsen, J., Laloli, L., Dijkman, R., Nielsen, A. L., Gad, H. H. & Hartmann, R. (2020). The IFNL4 Gene Is a Noncanonical Interferon Gene with a Unique but Evolutionarily Conserved Regulation. Journal of Virology, 94(5), e01535-19. https://doi.org/10.1128/JVI.01535-19

Wu, G., Schmid, M., Rib, L., Polak, P., Meola, N., Sandelin, A. & Jensen, T. H. (2020). A Two-Layered Targeting Mechanism Underlies Nuclear RNA Sorting by the Human Exosome. Cell Reports, 30(7), 2387-2401. https://doi.org/10.1016/j.celrep.2020.01.068

Fujimoto, M., Khoury, J. C., Khoury, P. R., Kalra, B., Kumar, A., Sluss, P., Oxvig, C., Hwa, V. & Dauber, A. (2020). Anthropometric and biochemical correlates of PAPP-A2, free IGF-I, and IGFBP-3 in childhood. European Journal of Endocrinology, 182(3), 363-374. https://doi.org/10.1530/EJE-19-0859

Bekalu, Z. E., Madsen, C. K., Dionisio, G., Holme, I. B., Jørgensen, L. N., Fomsgaard, I. S. & Brinch-Pedersen, H. (2020). Overexpression of nepenthesin HvNEP-1 in barley endosperm reduces fusarium head blight and mycotoxin accumulation. Agronomy, 10(2), [203]. https://doi.org/10.3390/agronomy10020203

Nagaraj, M., Ahmed, M., Lyngsø, J., Vad, B. S., Bøggild, A., Fillipsen, A., Pedersen, J. S., Otzen, D. E. & Akbey, Ü. (2020). Predicted Loop Regions Promote Aggregation: A Study of Amyloidogenic Domains in the Functional Amyloid FapC. Journal of Molecular Biology, 432(7), 2232-2252. https://doi.org/10.1016/j.jmb.2020.01.044

Ask, B., Christensen, O. F., Heidaritabar, M., Madsen, P. & Nielsen, H. M. (2020). The predictive ability of indirect genetic models is reduced when culled animals are omitted from the data. Genetics, selection, evolution : GSE, 52(1), [8]. https://doi.org/10.1186/s12711-020-0527-x

Haneke, K., Schott, J., Lindner, D., Hollensen, A. K., Damgaard, C. K., Mongis, C., Knop, M., Palm, W., Ruggieri, A. & Stoecklin, G. (2020). CDK1 couples proliferation with protein synthesis. The Journal of Cell Biology, 219(3), [e201906147]. https://doi.org/10.1083/jcb.201906147

Jensen, R. K., Jabs, F., Miehe, M., Mølgaard, B., Pfützner, W., Möbs, C., Spillner, E. & Andersen, G. R. (2020). Structure of intact IgE and the mechanism of ligelizumab revealed by electron microscopy. Allergy: European Journal of Allergy and Clinical Immunology, 75(8). https://doi.org/10.1111/all.14222

Jensen, M. F., Nedergaard, S., Nielsen, H. N., Skovgaard, N., Stevnsner, T. V. & Wang, T. (2020). Endothelin-1 induces a strong pressor effect in ball pythons (Python regius). Comparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology, 241, [110620]. https://doi.org/10.1016/j.cbpa.2019.110620

Nielsen, N. S., Poulsen, E. T., Lukassen, M. V., Chao Shern, C., Mogensen, E. H., Weberskov, C. E., DeDionisio, L., Schauser, L., Moore, T. C. B., Otzen, D. E., Hjortdal, J. & Enghild, J. J. (2020). Biochemical mechanisms of aggregation in TGFBI-linked corneal dystrophies. Progress in Retinal and Eye Research, 77, [100843]. https://doi.org/10.1016/j.preteyeres.2020.100843

Juul-Madsen, K., Qvist, P., Bendtsen, K. L., Langkilde, A. E., Vestergaard, B., Howard, K., Dehesa-Etxebeste, M., Paludan, S. R., Andersen, G. R., Jensen, P. H., Otzen, D. E., Romero-Ramos, M. & Vorup-Jensen, T. (2020). Size-Selective Phagocytic Clearance of Fibrillar α-Synuclein through Conformational Activation of Complement Receptor 4. Journal of Immunology, 204(5), 1345-1361. https://doi.org/10.4049/jimmunol.1900494

Liu, D., Geary, C. W., Chen, G., Shao, Y., Li, M., Mao, C., Andersen, E. S., Piccirilli, J. A., Rothemund, P. W. K. & Weizmann, Y. (2020). Branched kissing loops for the construction of diverse RNA homooligomeric nanostructures. Nature Chemistry, 12(3), 249-259. https://doi.org/10.1038/s41557-019-0406-7

Shah, N., Wakabayashi, T., Kawamura, Y., Skovbjerg, C. K., Wang, M-Z., Mustamin, Y., Isomura, Y., Gupta, V., Jin, H., Mun, T., Sandal, N., Azuma, F., Fukai, E., Seren, Ü., Kusakabe, S., Kikuchi, Y., Nitanda, S., Kumaki, T., Hashiguchi, M. ... Andersen, S. U. (2020). Extreme genetic signatures of local adaptation during Lotus japonicus colonization of Japan. Nature Communications, 11(1), [253]. https://doi.org/10.1038/s41467-019-14213-y

Sochaj-Gregorczyk, A., Ksiazek, M., Waligorska, I., Straczek, A., Benedyk, M., Mizgalska, D., Thøgersen, I. B., Enghild, J. J. & Potempa, J. (2020). Plasmin inhibition by bacterial serpin: Implications in gum disease. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(1), 619-630. https://doi.org/10.1096/fj.201901490RR

Silla, T., Schmid, M., Dou, Y., Garland, W., Milek, M., Imami, K., Johnsen, D., Polák, P., Andersen, J. S., Selbach, M., Landthaler, M. & Jensen, T. H. (2020). The human ZC3H3 and RBM26/27 proteins are critical for PAXT-mediated nuclear RNA decay. Nucleic Acids Research, 48(5), 2518-2530. https://doi.org/10.1093/nar/gkz1238

Møller, I. M., Igamberdiev, A. U., Bykova, N. V., Finkemeier, I., Rasmusson, A. G. & Schwarzländer, M. (2020). Matrix Redox Physiology Governs the Regulation of Plant Mitochondrial Metabolism through Post-Translational Protein Modifications. The Plant Cell, 32(3), 573-594. https://doi.org/10.1105/tpc.19.00535

Hayashi, Y., Takamiya, M., Jensen, P. B., Ojea-Jiménez, I., Claude, H., Antony, C., Kjaer-Sorensen, K., Grabher, C., Boesen, T., Gilliland, D., Oxvig, C., Strähle, U. & Weiss, C. (2020). Differential Nanoparticle Sequestration by Macrophages and Scavenger Endothelial Cells Visualized in Vivo in Real-Time and at Ultrastructural Resolution. ACS Nano, 14(2), 1665-1681. https://doi.org/10.1021/acsnano.9b07233

Dyla, M., Kjærgaard, M., Poulsen, H. & Nissen, P. (2020). Structure and Mechanism of P-Type ATPase Ion Pumps. Annual Review of Biochemistry, 89, 583-603. https://doi.org/10.1146/annurev-biochem-010611-112801

Nietzel, T., Mostertz, J., Ruberti, C., Née, G., Fuchs, P., Wagner, S., Moseler, A., Müller-Schüssele, S. J., Benamar, A., Poschet, G., Büttner, M., Møller, I. M., Lillig, C. H., Macherel, D., Wirtz, M., Hell, R., Finkemeier, I., Meyer, A. J., Hochgräfe, F. & Schwarzländer, M. (2020). Redox-mediated kick-start of mitochondrial energy metabolism drives resource-efficient seed germination. Proceedings of the National Academy of Sciences of the United States of America, 117(1), 741-751. https://doi.org/10.1073/pnas.1910501117

Menbari, M. N., Rahimi, K., Ahmadi, A., Mohammadi-Yeganeh, S., Elyasi, A., Darvishi, N., Hosseini, V. & Abdi, M. (2020). miR-483-3p suppresses the proliferation and progression of human triple negative breast cancer cells by targeting the HDAC8>oncogene. Journal of Cellular Physiology, 235(3), 2631-2642. https://doi.org/10.1002/jcp.29167

Sullivan, A. R., Eldfjell, Y., Schiffthaler, B., Delhomme, N., Asp, T., Hebelstrup, K., Keech, O., Öberg, L., Møller, I. M., Arvestad, L., Street, N. R. & Wang, X-R. (2020). The mitogenome of Norway spruce and a reappraisal of mitochondrial recombination in plants. Genome Biology and Evolution, 12(1), 3586-3598. https://doi.org/10.1093/gbe/evz263

Hansen, S. F., Hogan, S. A., Tobin, J., Rasmussen, J. T., Larsen, L. B. & Wiking, L. (2020). Microfiltration of raw milk for production of high-purity milk fat globule membrane material. Journal of Food Engineering, 276, [109887]. https://doi.org/10.1016/j.jfoodeng.2019.109887

Zhong, Y., Sagnelli, D., Topbjerg, H. B., Hasler-Sheetal, H., Andrzejczak, O. A., Hooshmand, K., Gislum, R., Jiang, D., Møller, I. M., Blennow, A. & Hebelstrup, K. H. (2020). Expression of starch-binding factor CBM20 in barley plastids controls the number of starch granules and the level of CO2 fixation. Journal of Experimental Botany, 71(1), 234-246. https://doi.org/10.1093/jxb/erz401

Petersen, D., Reinholdt, P., Szomek, M., Hansen, S. K., Poongavanam, V., Dupont, A., Heegaard, C. W., Krishnan, K., Fujiwara, H., Covey, D. F., Ory, D. S., Kongsted, J. & Wüstner, D. (2020). Binding and intracellular transport of 25-hydroxycholesterol by Niemann-Pick C2 protein. Biochimica et Biophysica Acta - Biomembranes, 1862(2), [183063]. https://doi.org/10.1016/j.bbamem.2019.183063

Thomasen, J. R., Liu, H. & Sørensen, A. C. (2020). Genotyping more cows increases genetic gain and reduces rate of true inbreeding in a dairy cattle breeding scheme using female reproductive technologies. Journal of Dairy Science, 103(1), 597-606. https://doi.org/10.3168/jds.2019-16974

Davis, R. B., Norberg, E. & Fogh, A. (2020). Estimation of genetic parameters for young stock survival in beef x dairy crossbred calves. Animal, 14(3), 445-451. [1751731119002386]. https://doi.org/10.1017/S1751731119002386

Lewinska, A., Sodagam, L., Bloniarz, D., Siems, K., Wnuk, M. & Rattan, S. (2020). Plant-derived molecules α-boswellic acid acetate, praeruptorin-A and salvianolic acid-B have age-related differential effects in young and senescent human fibroblasts in vitro. Molecules, 25(1), [141]. https://doi.org/10.3390/molecules25010141

Pallesen, L. T., Gustafsen, C., Cramer, J., Petersen, S. V., Thirup, S. S., Madsen, P. & Petersen, C. M. (2020). PAK kinases targets sortilin and modulates its sorting. Molecular and Cellular Biology, 40(3), [e00411-19]. https://doi.org/10.1128/MCB.00411-19

Clasen, J. B., Fikse, W. F., Kargo, M., Rydhmer, L., Strandberg, E. & Østergaard, S. (2020). Economic consequences of dairy crossbreeding in conventional and organic herds in Sweden. Journal of Dairy Science, 103(1), 514-528. https://doi.org/10.3168/jds.2019-16958

Christensen, B., Karlsen, N. J., Jørgensen, S. D. S., Jacobsen, L. N., Ostenfeld, M. S., Petersen, S. V., Müllertz, A. & Sørensen, E. S. (2020). Milk osteopontin retains integrin-binding activity after in vitro gastrointestinal transit. Journal of Dairy Science, 103(1), 42-51. https://doi.org/10.3168/jds.2019-17212

Pedersen, J. N., Lyngsø, J., Zinn, T., Otzen, D. & Pedersen, J. S. (2020). A complete picture of protein unfolding and refolding in surfactants. Chemical Science, 11(3), 699-712. https://doi.org/10.1039/C9SC04831F

Matamoros, M. A., Cutrona, M. C., Wienkoop, S., Begara-Morales, J. C., Sandal, N., Orera, I., Barroso, J. B., Stougaard, J. & Becana, M. (2020). Altered plant and nodule development and protein S-nitrosylation in Lotus japonicus mutants deficient in S-nitrosoglutathione reductases. Plant and Cell Physiology, 61(1), 105-117. https://doi.org/10.1093/pcp/pcz182

van Diggelen, F., Frank, S. A., Somavarapu, A. K., Scavenius, C., Apetri, M. M., Nielsen, J., Tepper, A. W. J. W., Enghild, J. J. & Otzen, D. E. (2020). The interactome of stabilized α-synuclein oligomers and neuronal proteins. The FEBS Journal, 287(10), 2037-2054. https://doi.org/10.1111/febs.15124

Wang, Y., Holleufer, A., Gad, H. H. & Hartmann, R. (2020). Length dependent activation of OAS proteins by dsRNA. Cytokine, 126, [154867]. https://doi.org/10.1016/j.cyto.2019.154867

Rattan, S. (2020). Naive extrapolations, overhyped claims and empty promises in ageing research and interventions need avoidance. Biogerontology, 21(4), 415-421. https://doi.org/10.1007/s10522-019-09851-0

Linova, M. Y., Risør, M. W., Jørgensen, S. E., Mansour, Z., Kaya, J., Sigurdarson, J. J., Enghild, J. J. & Karring, H. (2020). A novel approach for production of an active N-terminally truncated Ulp1 (SUMO protease 1) catalytic domain from Escherichia coli inclusion bodies. Protein Expression and Purification, 166, [105507]. https://doi.org/10.1016/j.pep.2019.105507

Rasmussen, H. Ø., Enghild, J. J., Otzen, D. E. & Pedersen, J. S. (2020). Unfolding and partial refolding of a cellulase from the SDS-denatured state: From β-sheet to α-helix and back. B B A - General Subjects, 1864(1), 129434 1-12. [129434]. https://doi.org/10.1016/j.bbagen.2019.129434