Peer-reviewed articles

Publications from the department

Journal covers made by researchers from our department

Peer-reviewed publications at MBG - 2025

Paiva, P., Teixeira, L. M. C., Ferreira, P., Otzen, D. E., Fernandes, P. A. & Ramos, M. J. (2025). Transforming Computational Power into Environmental Solutions: HPC-driven Research on Urethanase-mediated Plastic Degradation. Procedia Computer Science, 267, 207-217. https://doi.org/10.1016/j.procs.2025.08.247

Hu, Q., Sitsel, O., Bågenholm, V., Grønberg, C., Lyu, P., Pii Svane, A. S., Andersen, K. R., Laursen, N. S., Meloni, G., Nissen, P., Juhl, D. W., Nielsen, J. T., Nielsen, N. C. & Gourdon, P. (2025). Transition metal transporting P-type ATPases: terminal metal-binding domains serve as sensors for autoinhibitory tails. FEBS journal, 292(7), 1654-1674. https://doi.org/10.1111/febs.17330

Schulz, L., Ung, K. L., Zuzic, L., Koutnik-Abele, S., Schiøtt, B., Stokes, D. L., Pedersen, B. P. & Hammes, U. Z. (2025). Transport of phenoxyacetic acid herbicides by PIN-FORMED auxin transporters. Nature Plants, 11(5), 1049-1059. https://doi.org/10.1038/s41477-025-01984-0

Auxillos, J., Stigliani, A., Vaagensø, C. S., Garland, W., Niazi, A. M., Valen, E., Jensen, T. H. & Sandelin, A. (2025). True length of diverse capped RNA sequencing (TLDR-seq): 5'-3'-end sequencing of capped RNAs regardless of 3'-end status. Nucleic Acids Research, 53(6), Article gkaf240. https://doi.org/10.1093/nar/gkaf240

Tsitsikli, M., Simonsen, B., Luu, T. B., Larsen, M. M., Andersen, C. G., Gysel, K., Lironi, D., Krönauer, C., Rübsam, H., Hansen, S. B., Bærentsen, R., Wulff, J. L., Johansen, S. H., Sezer, G., Stougaard, J., Andersen, K. R. & Radutoiu, S. (2025). Two residues reprogram immunity receptors for nitrogen-fixing symbiosis. Nature, 443-450. https://doi.org/10.1038/s41586-025-09696-3

TRACERx Consortium (2025). Ultrasensitive ctDNA detection for preoperative disease stratification in early-stage lung adenocarcinoma. Nature Medicine, 31(1), 70-76. https://doi.org/10.1038/s41591-024-03216-y

M. Løber, I. M., Hedemann, M. S., Villesen, P. & Nielsen, K. L. (2025). Untangling the Postmortem Metabolome: A Machine Learning Approach for Accurate PMI Estimation. Analytical Chemistry, 97(30), 16123-16132. https://doi.org/10.1021/acs.analchem.4c05796

Paiva, P., Teixeira, L. M. C., Wei, R., Liu, W., Weber, G., Morth, J. P., Westh, P., Petersen, A. R., Johansen, M. B., Sommerfeldt, A., Sandahl, A., Otzen, D. E., Fernandes, P. A. & Ramos, M. J. (2025). Unveiling the enzymatic pathway of UMG-SP2 urethanase: insights into polyurethane degradation at the atomic level. Chemical Science, 16(5), 2437-2452. https://doi.org/10.1039/d4sc06688j

Hollensen, A. K., Sørensen, M. H., Thomsen, S. V., Thomsen, H. S. & Damgaard, C. K. (2025). Using circular RNAs to target toxic RNA-binding proteins in amyotrophic lateral sclerosis. Molecular Therapy Methods and Clinical Development, 33(3), Article 101525. https://doi.org/10.1016/j.omtm.2025.101525

Ghouse, J., Ahlberg, G., Albertsen Rand, S., Salling Olesen, M., Vilhjalmsson, B., Stender, S. & Bundgaard, H. (2025). Within-person stability of lipoprotein(a) concentration. European Heart Journal, 46(12), 1159-1161. https://doi.org/10.1093/eurheartj/ehae652

Eg Gadegaard, I. S., Eskildsen, M. H., Østergaard, S. K., Nielsen, J. L. & Rasmussen, J. T. (2025). Xanthine oxidase-lactoperoxidase system: Dose-dependent antibacterial effects and global gene expression changes in infant oral microbiota. Food Research International, 201, Article 115596. https://doi.org/10.1016/j.foodres.2024.115596

Shiraz, M. G., Nielsen, J., Widmann, J., Chung, K. H. K., Davis, T. P., Rasmussen, C., Scavenius, C., Enghild, J. J., Martin-Gallausiaux, C., Singh, Y., Javed, I. & Otzen, D. E. (2025). Young rat microbiota extracts strongly inhibit fibrillation of α-synuclein and protect neuroblastoma cells and zebrafish against α-synuclein toxicity. Molecules and Cells, 48(1), Article 100161. https://doi.org/10.1016/j.mocell.2024.100161

Christiansen, M. P. V. & Hammer, B. (2025). Δ-model correction of foundation model based on the model’s own understanding. Journal of Chemical Physics, 162(18), Article 184701. https://doi.org/10.1063/5.0268264

Displaying results 201 to 213 out of 213

Peer-reviewed publications at MBG - all years

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McLain, A., Saffie-Siebert, S. R., Nielsen, N. S., Patterson, B., Scavenius, C., Enghild, J. J., Marshall, J., Baran-Rachwalska, P., Welsh, M., Sutera, F. M., Moore, L., Willoughby, C., Nesbit, M. A. & Moore, T. (2025). Topical mutant allele-specific siRNA delivery for treatment of Meesmann epithelial corneal dystrophy and elucidation of disease biomarkers. Journal of Controlled Release, 388, Article 114315. https://doi.org/10.1016/j.jconrel.2025.114315

André, A. A. M., Rehnberg, N., Garg, A. & Kjærgaard, M. (2025). Toward Design Principles for Biomolecular Condensates for Metabolic Pathways. Advanced Biology, 9(5), Article 2400672. https://doi.org/10.1002/adbi.202400672

TRACERx Consortium (2025). TRACERx analysis identifies a role for FAT1 in regulating chromosomal instability and whole-genome doubling via Hippo signalling. Nature Cell Biology, 27(1), 154-168. Article 4871. https://doi.org/10.1038/s41556-024-01558-w

Pedersen, E. M., Wimberley, T. & Vilhjálmsson, B. J. (2024). A cautionary tale for Alzheimer’s disease GWAS by proxy: Genetic epidemiology. Nature Genetics, 56(12), 2590-2591. Article 99. https://doi.org/10.1038/s41588-024-02023-y

García-Soto, I., Andersen, S. U., Monroy-Morales, E., Robledo-Gamboa, M., Guadarrama, J., Aviles-Baltazar, N. Y., Serrano, M., Stougaard, J. & Montiel, J. (2024). A collection of novel Lotus japonicus LORE1 mutants perturbed in the nodulation program induced by the Agrobacterium pusense strain IRBG74. Frontiers in Plant Science, 14, Article 1326766. https://doi.org/10.3389/fpls.2023.1326766

Hansen, S. B., Luu, T. B., Gysel, K., Lironi, D., Krönauer, C., Rübsam, H., Jensen, I. B., Tsitsikli, M., Birkefeldt, T. G., Trgovcevic, A., Stougaard, J., Radutoiu, S. & Andersen, K. R. (2024). A conserved juxtamembrane motif in plant NFR5 receptors is essential for root nodule symbiosis. Proceedings of the National Academy of Sciences of the United States of America, 121(46), Article e2405671121. https://doi.org/10.1073/pnas.2405671121

Tejero, O., Pamula, F., Koyanagi, M., Nagata, T., Afanasyev, P., Das, I., Deupi, X., Sheves, M., Terakita, A., Schertler, G. F. X., Rodrigues, M. J. & Tsai, C. J. (2024). Active state structures of a bistable visual opsin bound to G proteins. Nature Communications, 15(1), Article 8928. https://doi.org/10.1038/s41467-024-53208-2

Imamura, K., Garland, W., Schmid, M., Jakobsen, L., Sato, K., Rouvière, J. O., Jakobsen, K. P., Burlacu, E., Lopez, M. L., Lykke-Andersen, S., Andersen, J. S. & Jensen, T. H. (2024). A functional connection between the Microprocessor and a variant NEXT complex. Molecular Cell, 84(21), 4158-4174.e6. https://doi.org/10.1016/j.molcel.2024.10.015

Krissanaprasit, A., Mihalko, E., Meinhold, K., Simpson, A., Sollinger, J., Pandit, S., Dupont, D. M., Kjems, J., Brown, A. C. & LaBean, T. H. (2024). A functional RNA-origami as direct thrombin inhibitor with fast-acting and specific single-molecule reversal agents in vivo model. Molecular Therapy, 32(7), 2286-2298. https://doi.org/10.1016/j.ymthe.2024.05.002

Vilstrup, A. P., Gupta, A., Rasmussen, A. J., Ebert, A., Riedelbauch, S., Lukassen, M. V., Hayashi, R. & Andersen, P. (2024). A germline PAF1 paralog complex ensures cell type-specific gene expression. Genes & Development, 38(17-20), 866-886. https://doi.org/10.1101/gad.351930.124

Lashkari, S., Jensen, S. K., Foldager, L., Larsen, T. & Vestergaard, M. (2024). A high fat to vitamin E ratio in the feed protects and improves uptake of the natural form of vitamin E in postweaning calves. Journal of Animal Physiology and Animal Nutrition, 108(3), 724-734. https://doi.org/10.1111/jpn.13926

Yamamoto, S., Nakamura, H., Kawamura, Y. K., Kitazawa, T., Kimura, M. & Kitazawa, Y. (2024). Alkoxy Substituted Brominated closo-Dodecaborates with Functionalized Aliphatic Spacers. Chemistry, 6(6), 1635-1644. https://doi.org/10.3390/chemistry6060099

Demircan, N., Sonmez, M. C., Akyol, T. Y., Ozgur, R., Turkan, I., Dietz, K. J. & Uzilday, B. (2024). Alternative electron sinks in chloroplasts and mitochondria of halophytes as a safety valve for controlling ROS production during salinity. Physiologia Plantarum, 176(3), Article e14397. https://doi.org/10.1111/ppl.14397

Civit, L., Moradzadeh, N., Jonczyk, A., Neckermann, P., Asbach, B., Peterhoff, D., Wagner, R., Famulok, M., Mayer, G., Kjems, J. & Valero, J. (2024). A Multi-Faceted Binding Assessment of Aptamers Targeting the SARS-CoV-2 Spike Protein. International Journal of Molecular Sciences , 25(9), Article 4642. https://doi.org/10.3390/ijms25094642

Juul-Madsen, K., Parbo, P., Ismail, R., Ovesen, P. L., Schmidt, V., Madsen, L. S., Thyrsted, J., Gierl, S., Breum, M., Larsen, A., Andersen, M. N., Romero-Ramos, M., Holm, C. K., Andersen, G. R., Zhao, H., Schuck, P., Nygaard, J. V., Sutherland, D. S., Eskildsen, S. F. ... Vorup-Jensen, T. (2024). Amyloid-β aggregates activate peripheral monocytes in mild cognitive impairment. Nature Communications, 15(1), Article 1224. https://doi.org/10.1038/s41467-024-45627-y

Dinesen, A., Andersen, V. L., Elkhashab, M., Pilati, D., Bech, P., Fuchs, E., Samuelsen, T. R., Winther, A., Cai, Y., Märcher, A., Wall, A., Omer, M., Nielsen, J. S., Chudasama, V., Baker, J. R., Gothelf, K. V., Wengel, J., Kjems, J. & Howard, K. A. (2024). An Albumin-Holliday Junction Biomolecular Modular Design for Programmable Multifunctionality and Prolonged Circulation. Bioconjugate Chemistry, 35(2), 214-222. https://doi.org/10.1021/acs.bioconjchem.3c00491

Montalbano, S., Krebs, M. D., Rosengren, A., Vaez, M., Hellberg, K. L. G., Mortensen, P. B., Børglum, A. D., Geschwind, D. H., Raznahan, A., Thompson, W. K., Helenius, D., Werge, T., Ingason, A. & iPSYCH Investigators (2024). Analysis of exonic deletions in a large population study provides novel insights into NRXN1 pathology. npj Genomic Medicine, 9(1), Article 67. https://doi.org/10.1038/s41525-024-00450-8

Fleming, S. A., Reyes, S. M., Donovan, S. M., Hernell, O., Jiang, R., Lönnerdal, B., Neu, J., Steinman, L., Sørensen, E. S., West, C. E., Kleinman, R. & Wallingford, J. C. (2024). An expert panel on the adequacy of safety data and physiological roles of dietary bovine osteopontin in infancy. Frontiers in nutrition, 11, Article 1404303. https://doi.org/10.3389/fnut.2024.1404303

Vallina, N. S., McRae, E. K. S., Geary, C. & Andersen, E. S. (2024). An RNA origami robot that traps and releases a fluorescent aptamer. Science Advances, 10(12), Article eadk1250. https://doi.org/10.1126/sciadv.adk1250

Guerreiro, I., Rang, F. J., Kawamura, Y. K., Kroon-Veenboer, C., Korving, J., Groenveld, F. C., van Beek, R. E., Lochs, S. J. A., Boele, E., Peters, A. H. M. F. & Kind, J. (2024). Antagonism between H3K27me3 and genome-lamina association drives atypical spatial genome organization in the totipotent embryo. Nature Genetics, 56(10), 2228-2237. https://doi.org/10.1038/s41588-024-01902-8

Otzen, D. E. (2024). Antibodies and α-synuclein: What to target against Parkinson's Disease? Biochimica et Biophysica Acta - Proteins and Proteomics, 1872(2), Article 140943. https://doi.org/10.1016/j.bbapap.2023.140943

Pierre-Ferrer, S., Collins, B., Lukacsovich, D., Wen, SA., Cai, Y., Winterer, J., Yan, J., Pedersen, L., Földy, C. & Brown, S. A. (2024). A phosphate transporter in VIPergic neurons of the suprachiasmatic nucleus gates locomotor activity during the light/dark transition in mice. Cell Reports, 43(5), Article 114220. https://doi.org/10.1016/j.celrep.2024.114220

Boegholm, N., Petriman, N. A., Tanvir, N. M. & Lorentzen, E. (2024). Architecture of RabL2-associated complexes at the ciliary base: A structural modeling perspective: Deciphering the structural organization of ciliary RabL2 complexes. BioEssays, 46(9), Article 2300222. https://doi.org/10.1002/bies.202300222

Mirarab, S., Rivas-González, I., Feng, S., Stiller, J., Fang, Q., Mai, U., Hickey, G., Chen, G., Brajuka, N., Fedrigo, O., Formenti, G., Wolf, J. B. W., Howe, K., Antunes, A., Schierup, M. H., Paten, B., Jarvis, E. D., Zhang, G. & Braun, E. L. (2024). A region of suppressed recombination misleads neoavian phylogenomics. Proceedings of the National Academy of Sciences (PNAS), 121(15), Article e2319506121. https://doi.org/10.1073/pnas.2319506121

Hejlesen, R., Scheffler, F. B., Byrge, C. G., Kjær-Sørensen, K., Oxvig, C., Fago, A. & Malte, H. (2024). Assessing metabolic rates in zebrafish using a 3D-printed intermittent-flow respirometer and swim tunnel system. Biology Open, 13(6), Article bio060375. https://doi.org/10.1242/bio.060375

Garland, W., Rouvière, J. O. & Heick Jensen, T. (2024). Assigning function to an unexplored Integrator module. Molecular Cell, 84(13), 2405-2406. https://doi.org/10.1016/j.molcel.2024.06.014

Dijkema, F. M., Escarpizo-Lorenzana, M. I., Nordentoft, M. K., Rabe, H. C., Sahin, C., Landreh, M., Branca, R. M., Sørensen, E. S., Christensen, B., Prestel, A., Teilum, K. & Winther, J. R. (2024). A suicidal and extensively disordered luciferase with a bright luminescence. Protein Science, 33(8), Article e5115. https://doi.org/10.1002/pro.5115

Santos, J., Cuellar, J., Pallarès, I., Byrd, E. J., Lends, A., Moro, F., Abdul-Shukkoor, M. B., Pujols, J., Velasco-Carneros, L., Sobott, F., Otzen, D. E., Calabrese, A. N., Muga, A., Pedersen, J. S., Loquet, A., Valpuesta, J. M., Radford, S. E. & Ventura, S. (2024). A Targetable N-Terminal Motif Orchestrates α-Synuclein Oligomer-to-Fibril Conversion. Journal of the American Chemical Society, 146(18), 12702-12711. https://doi.org/10.1021/jacs.4c02262

Vieira de Sá, R., Sudria-Lopez, E., Cañizares Luna, M., Harschnitz, O., van den Heuvel, D. M. A., Kling, S., Vonk, D., Westeneng, H. J., Karst, H., Bloemenkamp, L., Varderidou-Minasian, S., Schlegel, D. K., Mars, M., Broekhoven, M. H., van Kronenburg, N. C. H., Adolfs, Y., Vangoor, V. R., de Jongh, R., Ljubikj, T. ... Pasterkamp, R. J. (2024). ATAXIN-2 intermediate-length polyglutamine expansions elicit ALS-associated metabolic and immune phenotypes. Nature Communications, 15(1), Article 7484. https://doi.org/10.1038/s41467-024-51676-0

Kofod Petersen, A., Forgie, A. H., Bindslev, D. A., Villesen, P. & Staun Larsen, L. (2024). Automatic removal of soft tissue from 3D dental photo scans; an important step in automating future forensic odontology identification. Scientific Reports, 14, Article 12421. https://doi.org/10.1038/s41598-024-63198-2

Otzen, D. & d'Angelo, J. (2024). BBA: 2024 and beyond. Biochimica et Biophysica Acta - General Subjects, 1868(2), Article 130524. https://doi.org/10.1016/j.bbagen.2023.130524

Kobek-Kjeldager, C., Jensen, L. D., Foldager, L., Gould, L. M., Thodberg, K., Schrøder-Petersen, D. L. & Herskin, M. S. (2024). Behaviour of cull sows during transport to slaughter – Effects of journey duration, a stationary period and temperature. Applied Animal Behaviour Science, 271, Article 106174. https://doi.org/10.1016/j.applanim.2024.106174

Overgaard, C. K., Jamy, M., Radutoiu, S., Burki, F. & Dueholm, M. K. D. (2024). Benchmarking long-read sequencing strategies for obtaining ASV-resolved rRNA operons from environmental microeukaryotes. Molecular Ecology Resources, 24(7), Article e13991. https://doi.org/10.1111/1755-0998.13991

Palviainen, M., Puutio, J., Østergaard, R. H., Eble, J. A., Maaninka, K., Butt, U., Ndika, J., Kari, O. K., Kamali-Moghaddam, M., Kjaer-Sorensen, K., Oxvig, C., Aransay, A. M., Falcon-Perez, J. M., Federico, A., Greco, D., Laitinen, S., Hayashi, Y. & Siljander, P. R. M. (2024). Beyond basic characterization and omics: Immunomodulatory roles of platelet-derived extracellular vesicles unveiled by functional testing. Journal of Extracellular Vesicles, 13(10), Article e12513. https://doi.org/10.1002/jev2.12513

Loeschcke, V. & Schierup, M. H. (2024). Biographical sketch: Freddy Bugge Christiansen. Theoretical Population Biology, 156, 130. https://doi.org/10.1016/j.tpb.2024.02.006

Kaur, G. & Rattan, S. (Eds.) (2024). Brain and Mental Health in Ageing. Springer, Cham. Healthy Ageing and Longevity Vol. 21 https://doi.org/10.1007/978-3-031-68513-2

Chrenková, A., Bisiak, F. & Brodersen, D. E. (2024). Breaking bad nucleotides: understanding the regulatory mechanisms of bacterial small alarmone hydrolases. Trends in Microbiology, 32(8), 769-780. https://doi.org/10.1016/j.tim.2023.12.011

Displaying results 201 to 250 out of 5417

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Revised 13.11.2025

Lisbeth Heilesen

Department of Molecular Biology and Genetics

Peer-reviewed articles

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Peer-reviewed publications at MBG - 2025

Peer-reviewed publications at MBG - all years

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