Department of Molecular Biology and Genetics

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Peer-reviewed publications at MBG - 2025

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Steffensen, L. B., Poulsen, C. B., Shim, J., Bek, M., Jacobsen, K., Conover, C. A., Bentzon, J. F. & Oxvig, C. (2015). Myocardial and Peripheral Ischemia Causes an Increase in Circulating Pregnancy-Associated Plasma Protein-A in Non-atherosclerotic, Non-heparinized Pigs. Journal of Cardiovascular Translational Research, 8(9), 528-535. https://doi.org/10.1007/s12265-015-9656-y
Steffensen, L. B., Conover, C. A., Bjørklund, M. M., Ledet, T., Bentzon, J. F. & Oxvig, C. (2016). Stanniocalcin-2 overexpression reduces atherosclerosis in hypercholesterolemic mice. Atherosclerosis, 248, 36-43. https://doi.org/10.1016/j.atherosclerosis.2016.02.026
Steffensen, L. B., Conover, C. A. & Oxvig, C. (2019). PAPP-A and the IGF system in atherosclerosis: what's up, what's down? American journal of physiology. Heart and circulatory physiology, 317(5), H1039-H1049. https://doi.org/10.1152/ajpheart.00395.2019
Steengaard, J., Torvund-Jensen, J., Askbjerg, L., Clavsen, N., Kjaer-Sorensen, K., Oxvig, C. & Laursen, L. (2017). Identification of novel regulators of local MBP mRNA translation. Glia, 65(Special issue, S1), E397-E397. Article T12-076C .
The Baboon Genome Analysis Consortium (2018). Analysis of lineage-specific Alu subfamilies in the genome of the olive baboon, Papio anubis. Mobile DNA, 9(1), Article 10. https://doi.org/10.1186/s13100-018-0115-6
The Baboon Genome Analysis Consortium (2017). Alu insertion polymorphisms as evidence for population structure in baboons. Genome Biology and Evolution, 9(9), 2418-2427. https://doi.org/10.1093/gbe/evx184
Stec-Niemczyk, J., Pustelny, K., Kisielewska, M., Bista, M., Boulware, K., Stennicke, H., Thøgersen, I., Daugherty, P., Enghild, J., Popowicz, G., Dubin, A., Potempa, J. & Dubin, G. (2009). Structural and functional characterization of SplA, an exclusively specific protease of Staphylococcus aureus. Biochemical Journal. https://doi.org/10.1042/BJ20081351
Staunstrup, N. H., Moldt, B., Mátés, L., Villesen, P., Jakobsen, M., Ivics, Z., Izsvák, Z. & Mikkelsen, J. G. (2009). Hybrid Lentivirus-transposon Vectors With a Random Integration Profile in Human Cells. Molecular Therapy, 17(7), 1205-14. https://doi.org/10.1038/mt.2009.10
Staulund, J., Song, P., Qi, H., Thrane, L., Duedahl, P., Weiss, T., Moers, C., Keller, A. K., Nørregaard, R., Pedersen, M., Leuvenink, H., Kjems, J., Jespersen, B. & Eijken, M. (2022). Assessing the quality of donor kidneys during normothermic machine perfusion using nanoparticle-based vitality sensors. Abstract from 3rd ECTORS meeting, Rotterdam, Netherlands.
Starnawski, P., Bataillon, T., Ettema, T. J. G., Jochum, L. M., Schreiber, L., Chen, X., Lever, M. A., Polz, M. F., Jørgensen, B. B., Schramm, A. & Kjeldsen, K. U. (2017). Microbial community assembly and evolution in subseafloor sediment. Proceedings of the National Academy of Sciences (PNAS), 114(11), 2940-2945. https://doi.org/10.1073/pnas.1614190114
Starnawska, A., McQuillin, A., Demontis, D., Pen, A., Hedemand, A., Johannesen, M. D., Lescai, F., Als, T. D., Grove, J., Staunstrup, N. H., Nielsen, A. L., Jarram, A., O'Brian, N., Mors, O., Børglum, A. & Nyegaard, M. (2015). DNA methylation of CACNA1C in bipolar disorder. Poster session presented at ESHG 2015, Glasgow, United Kingdom.
Starnawska, A., Demontis, D., Pen, A., Hedemand, A., Nielsen, A. L., Staunstrup, N. H., Grove, J., Als, T. D., Jarram, A., O'Brien, N. L., Mors, O., McQuillin, A., Børglum, A. D. & Nyegaard, M. (2016). CACNA1C hypermethylation is associated with bipolar disorder. Translational Psychiatry, 6(6), e831. Article e831. https://doi.org/10.1038/tp.2016.99
Starnawska, A., Bukowski, L., Chernomorchenko, A., Elfving, B., Müller, H. K., van den Oord, E., Aberg, K., Guintivano, J., Grove, J., Mors, O., Børglum, A. D., Nielsen, A. L., Qvist, P. & Staunstrup, N. H. (2021). DNA methylation of the KLK8 gene in depression symptomatology. Clinical Epigenetics, 13(1), Article 200. https://doi.org/10.1186/s13148-021-01184-5
Stark, A., Lin, M. F., Kheradpour, P., Pedersen, J. S., Parts, L., Carlson, J. W., Crosby, M. A., Rasmussen, M. D., Roy, S., Deoras, A. N., Ruby, J. G., Brennecke, J., Hodges, E., Hinrichs, A. S., Caspi, A., Paten, B., Park, S.-W., Han, M. V., Maeder, M. L. ... Harvard FlyBase curators (2007). Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures. Nature, 450(7167), 219-32. https://doi.org/10.1038/nature06340
Stapulionis, R., Wang, Y., Dempsey, G. T., Khudaravalli, R., Nielsen, K. M., Cooperman, B. S., Goldman, Y. E. & Knudsen, C. R. (2008). Fast in vitro translation system immobilized on a surface via specific biotinylation of the ribosome. Biological Chemistry, 389(9), 1239-1249.
Staniec, D., Ksiazek, M., Thøgersen, I. B., Enghild, J. J., Sroka, A., Bryzek, D., Bogyo, M., Abrahamson, M. & Potempa, J. (2015). Calcium Regulates the Activity and Structural Stability of Tpr, a Bacterial Calpain-like Peptidase. Journal of Biological Chemistry, 290, 27248-27260. https://doi.org/10.1074/jbc.M115.648782
Stange, A. D., Zuzic, L., Schiøtt, B. & Berglund, N. A. (2025). Exploring insulin-receptor dynamics: Stability and binding mechanisms. Structure, 33(8), 1425-1435.e2. https://doi.org/10.1016/j.str.2025.04.022
Stambler, I., jin, K., Lederman, S., Barzilai, N., Olshansky, S. J., Omokaro, E., Barratt, J., Anisimov, V., Rattan, S., Yang, S., Forster, M. & Byles, J. (2018). Aging Health and R&D for Healthy Longevity Must Be Included into the WHO Work Program. Aging and Disease, 9(2), 331-333. https://doi.org/10.14336/AD.2017.1120
Stahl, E. A., Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., Wang, Y., Coleman, J. R. I., Gaspar, H. A., de Leeuw, C. A., Steinberg, S., Pavlides, J. M. W., Trzaskowski, M., Byrne, E. M., Pers, T. H., Holmans, P. A., Richards, A. L., Abbott, L. ... eQTLGen Consortium (2019). Genome-wide association study identifies 30 loci associated with bipolar disorder. Nature Genetics, 51(5), 793-803. https://doi.org/10.1038/s41588-019-0397-8
Stagsted, L. V. W., Daugaard, I. & Hansen, T. B. (2017). The agotrons: Gene regulators or Argonaute protectors? BioEssays, 39(4), Article 1600239. https://doi.org/10.1002/bies.201600239
Stagsted, L. V., Nielsen, K., Daugaard, I. & Hansen, T. B. (2019). Noncoding AUG circRNAs constitute an abundant and conserved subclass of circles. Life Science Alliance, 2(3), Article e201900398. https://doi.org/10.26508/lsa.201900398
Stagsted, L. V. W., O'Leary, E. T., Ebbesen, K. K. & Hansen, T. B. (2021). The RNA-binding protein SFPQ preserves long-intron splicing and regulates circRNA biogenesis in mammals. eLife, 10, Article e63088. https://doi.org/10.7554/eLife.63088
Staehr, C., Login, H., Melnikova, E., Bakun, M., Ziemlinska, E., Kisiswa, L., Berenji Ardestani, S., Nolte, S. S., Beck, H. C., Hansen, L. M. B., Postnov, D., Verkhratsky, A., Malik, A. R., Nykjær, A. & Matchkov, V. (2025). SorCS2 Is Important for Astrocytic Function in Neurovascular Signaling. Acta Physiologica (Print), 241(6), Article e70052. https://doi.org/10.1111/apha.70052
Staeheli, P., Ye, L., Schnepf, D., Becker, J., Ebert, K., Bernasconi, V., Gad, H. A., Tanriver, Y., Hartmann, R. & Lycke, N. (2017). IFN-lambda enhances IgG1 antibody production after intranasal immunization by a TSLP-dependent mechanism. Cytokine, 100, 152-153. https://ac.els-cdn.com/S1043466617302685/1-s2.0-S1043466617302685-main.pdf?_tid=726dea26-0ff7-11e8-90aa-00000aacb35f&acdnat=1518441789_b43d8e6c4fb02e32cfb50f164ebdbd15
Stack, M. S., Gately, S., Bafetti, L. M., Enghild, J. J. & Soff, G. A. (1999). Angiostatin inhibits endothelial and melanoma cellular invasion by blocking matrix-enhanced plasminogen activation. Biochemical Journal, 340 ( Pt 1), 77-84.
Stacey, S. N., Sulem, P., Zanon, C., Gudjonsson, S. A., Thorleifsson, G., Helgason, A., Jonasdottir, A., Besenbacher, S., Kostic, J. P., Fackenthal, J. D., Huo, D., Adebamowo, C., Ogundiran, T., Olson, J. E., Fredericksen, Z. S., Wang, X., Look, M. P., Sieuwerts, A. M., Martens, J. W. M. ... Stefansson, K. (2010). Ancestry-shift refinement mapping of the C6orf97-ESR1 breast cancer susceptibility locus. PLoS Genetics, 6(7), e1001029. https://doi.org/10.1371/journal.pgen.1001029
S∅rensen, E. S. & Petersen, T. E. (1994). Identification of two phosphorylation motifs in bovine osteopontin. Biochemical and Biophysical Research Communications, 198(1), 200-205. https://doi.org/10.1006/bbrc.1994.1028
Sprenger, R. R., Ostenfeld, M. S., Bjørnshave, A., Rasmussen, J. T. & Ejsing, C. S. (2024). Lipidomic Characterization of Whey Concentrates Rich in Milk Fat Globule Membranes and Extracellular Vesicles. Biomolecules, 14(1), Article 55. https://doi.org/10.3390/biom14010055
Sprenger, R. R., Bilgin, M., Ostenfeld, M. S., Bjørnshave, A., Rasmussen, J. T. & Ejsing, C. S. (2024). Dietary intake of a MFGM/EV-rich concentrate promotes accretion of very long odd-chain sphingolipids and increases lipid metabolic turnover at the whole-body level. Food Research International, 190, Article 114601. https://doi.org/10.1016/j.foodres.2024.114601
Speed, D., Hemani, G., Speed, M. S., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & Børglum, A. D. (2019). Investigating the causal relationship between neuroticism and depression via Mendelian Randomization. Acta Psychiatrica Scandinavica, 139(4), 395-397. https://doi.org/10.1111/acps.13009
Spahn, C. M., Gomez-Lorenzo, M. G., Grassucci, R. A., Jørgensen, R., Andersen, G. R., Beckmann, R., Penczek, P. A., Ballesta, J. P. & Frank, J. (2004). Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome. E M B O Journal, 23, 1008-1019.
Soyeurt, H., Froidmont, E., Dufrasne, I., Wang, Z., Gengler, N., Dehareng, F., GplusE Consortium & Grelet, C. (2019). Validation of the prediction of body weight from dairy cow characteristics and milk MIR spectra. In Book of Abstracts of the 70th Annual Meeting of the European Federation of Animal Science (Vol. 25, pp. 606). Wageningen Academic Publishers. https://doi.org/10.3920/978-90-8686-890-2
Sottrup-Jensen, L. & Andersen, G. R. (2014). Purification of human complement protein c5. In The Complete System: Mehods and Protocols (Vol. 1100, pp. 93-102). Springer. https://doi.org/10.1007/978-1-62703-724-2_7
SØRENSEN, ESBEN. S. & PETERSEN, TORBEN. E. (1995). Phosphorylation, Glycosylation, and Transglutaminase Sites in Bovine Osteopontin. Annals of the New York Academy of Sciences, 760(1), 363-366. https://doi.org/10.1111/j.1749-6632.1995.tb44658.x
Sørensen, B. K., Højrup, P., Østergaard, E., Jørgensen, C. S., Enghild, J., Ryder, L. R. & Houen, G. (2002). Silver staining of proteins on electroblotting membranes and intensification of silver staining of proteins separated by polyacrylamide gel electrophoresis. Anal. Biochem., 304, 33-41.
Sørensen, E. S., Møller, L., Vinter, M., Petersen, T. E. & Rasmussen, L. K. (2003). The phosphorylation pattern of human alphas 1-casein is markedly different from the ruminant species. FEBS journal, 270, 3651-3655.
Sørensen, E. S., Rasmussen, L. K. & Petersen, T. E. (1999). Component PP3 of bovine milk is a substrate for transglutaminase. Sequence location of putative cross-linking sites. J. Dairy Res., 66, 145-150.
Sørensen, A. B., Warming, S., Füchtbauer, E. M. & Pedersen, F. S. (2002). Alternative splicing, expression, and gene structure of the septin-like putative proto-oncogene Sint1. Gene, 285(1-2), 79-89.
Sørensen, M., Christensen, K., Stevnsner, T. V. & Christiansen, L. (2009). The Mn-superoxide dismutase single nucleotide polymorphism rs4880 and the glutathione peroxidase 1 single nucleotide polymorphism rs1050450 are associated with aging and longevity in the oldest old. Mechanisms of Ageing and Development, 130(5).
Sørensen, M., Diaz, R. G., Müller-Ohldach, M., Werner, A., Bohr, V., Osiewacz, H. D. & Stevnsner, T. V. (2009). A potential impact of DNA repair on ageing and lifespan in the ageing model organism Podospora anserine: decrease in mitochondrial DNA repair activity during ageing. Mechanisms of Ageing and Development, 130(8), 487-496.
Sørensen, M., Dato, S., Christensen, K., McGue, M., Stevnsner, T. V., Bohr, V. & Christiansen, L. (2010). Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data. Aging Cell, 9(6), 1010-1017. https://doi.org/10.1111/j.1474-9726.2010.00627.x.
Sørensen, M., Thinggaard, M., Nygaard, M., Dato, S., Tan, Q., Hjelmborg, J., Andersen-Ranberg, K., Stevnsner, T. V., Bohr, V., Kimura, M., Aviv, A., Christensen, K. & Christiansen, L. (2012). Genetic variation in TERT and TERC and human leukocyte telomere length and longevity: a cross-sectional and longitudinal analysis. Aging Cell, 11(2). https://doi.org/10.1111/j.1474-9726.2011.00775.x
Sørensen, R. S., Okholm, A. H., Schaffert, D. H., Kodal, A. L. B., Gothelf, K. V. & Kjems, J. (2013). Enzymatic Ligation of Large Biomolecules to DNA. ACS Nano, 7(9), 8098-8104. https://doi.org/10.1021/nn403386f
Sørensen, B. S., Sinding, J., Andersen, A. H., Alsner, J., Jensen, P. B. & Westergaard, O. (1992). Mode of action of topoisomerase II-targeting agents at a specific DNA sequence. Uncoupling the DNA binding, cleavage and religation events. Journal of Molecular Biology, 228(3), 778-786. https://doi.org/10.1016/0022-2836(92)90863-F
Sørensen, H. J., Foldager, L., Røge, R., Pristed, S. G., Andreasen, J. T. & Nielsen, J. (2014). An association between autumn birth and clozapine treatment in patients with schizophrenia: A population-based analysis. Nordic Journal of Psychiatry, 68(6), 428-432. https://doi.org/10.3109/08039488.2013.854408
Sørensen, J. L., Knudsen, M., Hansen, F. T., Olesen, C., Romans Fuertes, P., Lee, T. V., Søndergaard, T. E., Pedersen, C. N. S., Brodersen, D. E. & Giese, H. (2014). Fungal NRPS-dependent siderophores: From function to prediction. In J.-F. Martin, C. Garcia-Estrada & S. Zeilinger (Eds.), Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites (pp. 317-339). Springer. https://doi.org/10.1007/978-1-4939-1191-2_15
Sørensen, K. K., Simonsen, J. B., Maolanon, N. N., Stougaard, J. & Jensen, K. J. (2014). Chemically synthesized 58-mer LysM domain binds lipochitin oligosaccharide. ChemBioChem, 15(14), 2097-105. https://doi.org/10.1002/cbic.201402125
Sørensen, C. S., Runager, K. S., Scavenius, C., Jensen, M. M., Nielsen, N. S., Christiansen, G., Petersen, S. V., Karring, H., Sanggaard, K. W. & Enghild, J. J. (2015). Fibril core of transforming growth factor beta-induced protein (TGFBIp) facilitates aggregation of corneal TGFBIp. Biochemistry, 19(54), 2943-2956. https://doi.org/10.1021/acs.biochem.5b00292
Sørensen, H. V., Pedersen, J. N., Pedersen, J. S. & Otzen, D. E. (2017). Tailoring thermal treatment to form liprotide complexes between oleic acid and different proteins. Biochimica et Biophysica Acta - Proteins and Proteomics, 1865(6), 682–693. https://doi.org/10.1016/j.bbapap.2017.03.011
Sørensen, B. S., Fukata, H., Jensen, P. S., Andersen, A. H., Christiansen, K., Fukasawa, H. & Westergaard, O. (1991). Drug stimulated DNA cleavage mediated by cauliflower topoisomerase II. Plant Physiology, 95(2), 659-662. https://doi.org/10.1104/pp.95.2.659

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Lisbeth Heilesen