Peer-reviewed articles

Publications from the department

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Latest peer-reviewed publications at MBG

Tanvir, N. M. & Cell Map Project Team (2026). 3D nanoscale reconstruction of human airway multiciliogenesis reveals cellular architecture remodeling and cilia-mitochondria link via rootlets. Cell Reports, 45(7), Article 117714. https://doi.org/10.1016/j.celrep.2026.117714

Pitfield, J., Christiansen, M. P. V. & Hammer, B. (2026). Active Δ-learning with universal potentials for global structure optimization. Physical Chemistry Chemical Physics, 28(1), 912-926. https://doi.org/10.1039/d5cp04302f

Al-Momani, S. S., Ramsbottom, K., Collins, A., Boswell, E., Hendriks, I. A., Nielsen, M. L., Vertegaal, A. C. O., Hay, R. T., Sun, Z., Riverol, Y. P., Bowler-Barnett, E. H., Martin, M. J., Fan, J., Sadanandom, A., Deutsch, E. W., Vizcaíno, J. A. & Jones, A. R. (2026). A Landscape Analysis of Human SUMOylation. Molecular & Cellular Proteomics : MCP, 25(5), 101571. Article 101571. https://doi.org/10.1016/j.mcpro.2026.101571

Vestrheim, O., Zhao, H., Nielsen, A. B., Wili, N., Nielsen, N. C., Lyons, J. A., Mookerjee, R. P. & Städler, B. (2026). A Lipid-Conjugation Strategy for Intracellular Reactive Oxygen Species Control in Hepatic Cells. Angewandte Chemie - International Edition. Advance online publication. https://doi.org/10.1002/anie.5582949

Zhang, H., Windhorst, A., Bornhofen, E., Tulpova, Z., Novak, P., Macas, J., Simkova, H., Nadzieja, M., Kim, J. M., Cram, D., Cao, Y., Konkin, D. J. F., Sass, O., Welna, G., Himmelbach, A., Mascher, M., Link, W., Kwon, S.-J., Yang, T.-J. ... Jayakodi, M. (2026). Allelic variation at a single locus distinguishes spring and winter faba beans. Nature Genetics, 58(3), 655-663. https://doi.org/10.1038/s41588-026-02524-y

Kaas, M., Dinesen, S. B., Ahlgreen, O., Madsen, P., Mølgaard, S., Dalby, A., Gustafsen, C., Olsen, D., Duan, J., Vilstrup, J., Lende, J., Nordestgaard, S., Zayats, T., Knappskog, P. M., Johansson, S., Neckelmann, G., Franke, B., Thirup, S., Børglum, A. ... Skeldal, S. (2026). A low frequency damaging SORCS2 variant identified in a family with ADHD compromises receptor stability and quenches activity. Molecular Psychiatry, 31(3), 1311-1324. https://doi.org/10.1038/s41380-025-03242-3

Xi, X., Zhang, Y., Zhao, D., Chen, F. & Howard, K. A. (2026). A modular “Catch-and-Play” platform for rapid T-cell engager target assembly for personalised cancer treatment. Signal Transduction and Targeted Therapy, 11(1), Article 18. https://doi.org/10.1038/s41392-025-02557-5

Hao, D., Wang, X., Shang, G., Pektas, A., Purup, S. & Thomsen, B. (2026). Analysis of Colon Transcriptomes in a Porcine Model of Dextran Sodium Sulfate (DSS)-Induced Ulcerative Colitis. Biology, 15(14), Article 1123. https://doi.org/10.3390/biology15141123

Liu, J., Yan, S., Li, M., Shen, D., Tichá, M., Bærentsen, R., Andersen, K. R., Verbeek, F., Kulikova, O., Geurts, R., Bisseling, T. & Huisman, R. (2026). Ancestral functionality and symbiotic refinement of NIN in root nodule symbiosis. Nature Communications, 17(1), Article 4907. https://doi.org/10.1038/s41467-026-71330-1

Hopkinson, A. T., Wilson, A. M., Pitfield, J., Muiña, A. T., Rácz, R., Mifsud, D. V., Herczku, P., Lakatos, G., Sulik, B., Juhász, Z., Biri, S., McCullough, R. W., Mason, N. J., Scavenius, C., Hornekær, L. & Ioppolo, S. (2026). An interstellar energetic and non-aqueous pathway to peptide formation. Nature Astronomy, 10(4), 531-539. https://doi.org/10.1038/s41550-025-02765-7

D'Alessio, A. M., Yuan, H., Soria, L. R., Hansen, S. B., Boffa, I., Arena, P., Attianese, B., O'Sullivan, M., Cullinan, N., Pang, L., van Aalten, D. M. F., Brunetti-Pierri, N. & Lynch, S. A. (2026). An OGT Missense Variant With Impaired Enzyme Activity in a Child With Severe Developmental Delay and Hepatoblastoma. American Journal of Medical Genetics, Part A, 200(2), 502-510. https://doi.org/10.1002/ajmg.a.64275

Jensen, K. T., Viana de Almeida, A. C., Rönning, S., Karlander, M., Nielsen, N. S., Thøgersen, I., Malm, M., Andersen, G. R., Enghild, J. J., Rockberg, J. & Harwood, S. L. (2026). Antagonist nanobodies prevent protease inhibition by CD109. Journal of Biological Chemistry, 302(3), Article 111187. https://doi.org/10.1016/j.jbc.2026.111187

Rast, J. E., Rosso, A. L., James, B. D., Underwood, J. F. G., Bergstedt, J., Ahlqvist, V. H., Grove, J., Fang, F., Goldstein, N. D., Vivanti, G., Levine, S. Z., Nordström, A., Schendel, D., Lyall, K., Nordström, P., Ballin, M., Stafford, J., Naj, A. C., Lee, B. K. & LEGENNDS Consortium (2026). Association of neurodevelopmental conditions with Alzheimer's disease and related dementias and Parkinson's disease. The Journals of Gerontology. Series A: Biological Sciences & Medical Sciences, 81(4), Article glaf281. https://doi.org/10.1093/gerona/glaf281

Villesen, P., Nielsen, K. L. & Frisch, K. (2026). Automated separation of overlapping fingermarks by non-negative matrix factorization of DESI mass spectrometry imaging data. Analytical and Bioanalytical Chemistry, 418(14), 4321-4332. https://doi.org/10.1007/s00216-026-06574-3

Samanta, A., Malle, M. G., Tsang, E., Omer, M., Skaanning, M. K., Youssef, S., Kjems, J. & Gothelf, K. V. (2026). Bacteriophage-Mimetic DNA Origami Needle for Targeted Membrane Penetration and Cytosolic Cargo Delivery. Advanced Science, 13(10), Article e12844. https://doi.org/10.1002/advs.202512844

Rasmussen, A. M., Bouchard-Côté, A. & Pedersen, J. S. (2026). bayesReact: expression-coupled regulatory motif analysis detects microRNA activity across cancers, tissues, and at the single-cell level. Nucleic Acids Research, 54(4), Article gkag072. https://doi.org/10.1093/nar/gkag072

Golbek, T. W., Rasmussen, M. H., Bregnhøj, M., Boesen, T., Drace, T., Faase, R., Baio, J. E. & Weidner, T. (2026). Binding and orientation of ice nucleating proteins on hydrophilic and hydrophobic surfaces probed by photoelectron spectroscopies. Biointerphases, 21(3), Article 031002. https://doi.org/10.1116/6.0005223

Rosenbæk, C. H., Jiang, P., Dahl-Nielsen, S., Simonsen, M. B., Bojsen, A., Sprenger, R. R., Blans, K., Ejsing, C. S., Rasmussen, J. T. & Zachariassen, G. (2026). Bioactive components in preterm and term human milk compared to donor human milk: A pilot study. Clinical Nutrition ESPEN, 75, Article 103603. https://doi.org/10.1016/j.clnesp.2026.103603

Kjær, M. B., Jørgensen, A. G., Fjelstrup, S., Dupont, D. M., Bus, C., Oversoe, S. K., Kelsen, J., Kjems, J. & Grønbæk, H. (2026). Biomarker-directed aptamer panels for diagnosis and differentiation of neuroendocrine tumors. Journal of Neuroendocrinology, 38(3), Article e70146. https://doi.org/10.1111/jne.70146

ISEV workshop (2026). Biomolecular Corona of Extracellular Vesicles: Report on Isev Workshop. Journal of Extracellular Biology, 5(8), e70172. https://doi.org/10.1002/jex2.70172

Boonkaew, S. & Ferapontova, E. E. (2026). Capacitive Lateral Flow Test for Sub-fM Analysis of Serum HER-2/neu Using a Magnetic Cellulase-Linked Aptamer Sandwich Strategy. Analytical Chemistry, 98(2), 1370-1379. https://doi.org/10.1021/acs.analchem.5c05265

Bærentsen, R. L., Kronborg, K., Brodersen, D. E. & Zhang, Y. E. (2026). Catalytic mechanism and differential alarmone regulation of a conserved stringent nucleosidase. Structure, 34(1), 198-209.e4. https://doi.org/10.1016/j.str.2025.10.012

Andersen, L., Lindskrog, S. V., Nordentoft, I., Frydendahl, A., Nors, J., Henriksen, T. V., Rasmussen, M. H., Iversen, L. H., Gotschalck, K. A., Jensen, J. B., Dyrskjøt, L., Andersen, C. L. & Birkbak, N. J. (2026). Cell-Free DNA-Derived Immune Cell Ratios Uncover Cancer-Associated Systemic Changes. Cancer Research Communications, 6(4), 811-820. https://doi.org/10.1158/2767-9764.CRC-25-0747

Yan, K., Stanley, M., Raimi, O., Ferenbach, A. T., Dorfmueller, H. C. & van Aalten, D. M. F. (2026). Cell wall target fragment discovery using a low-cost, minimal fragment library. FEBS Letters, 600(11), 1638-1654. https://doi.org/10.1002/1873-3468.70281

Labianca, S., Lousdal, M. L., Krebs, M. D., Hansen, O. S., Hellberg, K. L. G., Lundberg, M., Sørensen, J. Ø., Gådin, J. R., Ohlsson, H., Grove, J., Børglum, A., Agerbo, E., Werge, T., Albiñana, C., Vilhjálmsson, B. J., Kendler, K. S., Plana-Ripoll, O. & Schork, A. J. (2026). Changes in Genetic Contributions to ASD and ADHD by Year of Diagnosis. JAMA Psychiatry. Advance online publication. https://doi.org/10.1001/jamapsychiatry.2026.1450

Utley, D., Budnick, A., Radutoiu, S. & Sederoff, H. (2026). Circular RNAs in Lotus japonicus Responses to Nutrient Supply and Mesorhizobium Symbiosis. Plant, Cell and Environment, 49(8), 4823-4839. https://doi.org/10.1111/pce.70496

Faber, A. H., Bataillon, T. & Ehlers, B. K. (2026). Climate-Driven Convergence of Chemical Ecotypes in Mediterranean Lamiaceae. Journal of Biogeography, 53(5), Article e70247. https://doi.org/10.1111/jbi.70247

Tong, T., Hendriksen, J. D., Elbæk, K. J., Molnar, K., Christiansen, F. V., Ozsvar, A., Eschen, J. T., Rodríguez-González, F. G., Pusat, I. D., Christensen, E. L., Rahbæk, M., Frederiksen, K. P., Cortnum, S. O. S., Sindby, A. K., Meier, K., Nikola , Sørensen, J. C. H., Ting, J. T., Capogna, M. ... Korshøj, A. R. (2026). Combined patch-clamp electrophysiology and single-cell genomic analysis reveal spiking tumor cells at the neocortical glioblastoma interface in humans. Neuro-Oncology, 28(6), 1442-1457. https://doi.org/10.1093/neuonc/noag059

Gázquez-Gutiérrez, A., Chin, P., Peris, G., Gordon, K., Marchante, P. G., Witteveldt, J., Tristán-Ramos, P., Rouvière, J. O., Knol, L. I., Ivens, A., López-Onieva, L., Estévez, A. M., Garland, W., Jensen, T. H., Heras, S. R. & Macias, S. (2026). Control of retrotransposon-driven activation of the interferon response by the double-stranded RNA binding protein DGCR8. Nucleic Acids Research, 54(5), Article gkag190. https://doi.org/10.1093/nar/gkag190

Lee, H., Ko, K., Kim, S., Lee, G., Kim, S., Lee, J., Song, D. Y., Bong, G., Han, J. H., Lee, J., Kim, Y. R., Lee, Y., Kim, E., Børglum, A. D., Grove, J., Kim, S. H., Sun, W., Yoo, H. J. & An, J. Y. (2026). Co-occurrence of rare variants implicates gene pairs in cytoskeletal pathways and is associated with increased severity in autism spectrum disorder. Genome Biology, 27(1), Article 147. https://doi.org/10.1186/s13059-026-04041-x

Marzookian, K., Aliakbari, F., Hourfar, H., Sabouni, F., Otzen, D. E. & Morshedi, D. (2026). Corrigendum to “The neuroprotective effect of human umbilical cord MSCs-derived secretome against α-synuclein aggregates on the blood-brain barrier” [Int. J. Biol. Macromol. Volume 290 (2025), 140387] (S0141813025009365), (10.1016/j.ijbiomac.2025.140387). International Journal of Biological Macromolecules, 337, Article 149909. https://doi.org/10.1016/j.ijbiomac.2025.149909

Khachadourian, V., Anderson, M., Arildskov, E. S., Grove, J., Reichenberg, A., Sandin, S., Schendel, D., Hansen, S. N., Croen, L. A. & Janecka, M. (2026). Cross-Setting Replication of the Associations Between Maternal Health and Autism. Journal of the American Academy of Child and Adolescent Psychiatry, 65(8), 1045-1053. https://doi.org/10.1016/j.jaac.2025.11.009

Jensen, R. K., Miehe, M., Gandini, R., Jørgensen, M. H., Spillner, E. & Andersen, G. R. (2026). Cryo-EM Structure of FcεRI Bound IgE Reveals Multiple Defined Conformations of the Fab-Fc Hinge. Allergy: European Journal of Allergy and Clinical Immunology, 81(6), 2047-2058. https://doi.org/10.1111/all.70132

Pedersen, K., Green, K., Kristoffersen, E. L., Schinkel, T., Hansen, A. G., Palarasah, Y., Rovsing, A. B., Andersen, E. S., Valero, J., Civit, L., Laursen, N. S., Troldborg, A., Degn, S. E. & Thiel, S. (2026). Curbing Autoimmunity: A New Fab Fragment Targeting CD40-CD40L Halts B-Cell Activation and Differentiation. European Journal of Immunology, 56(2), Article e70158. https://doi.org/10.1002/eji.70158

Kofod Petersen, A., Spin-Neto, R., Villesen, P. & Staun Larsen, L. (2026). Curvature-based 3D dental comparison to identify trauma-induced surface changes in human teeth: a forensic comparison study. Journal of Forensic Odonto-Stomatology, 43(3), 49-58.

Goto, T., Andersen, K. R., Bamba, M., Sato, S., Sugawara, M., Minamisawa, K., Kawaguchi, M., Stougaard, J. & Kawaharada, Y. (2026). Cyclophilin A-mediated cis/trans isomerization modulates RIN4 to control intracellular rhizobial infection in legumes. New Phytologist, 250(6), 3932-3945. https://doi.org/10.1111/nph.71147

Carneiro, I. S. M., Pedrosa, L. R. R., Corrêa, A. C. R., Soares, B. G. C., Rocha, L. S. O., Leal, L. C. P., Passos-Monteiro, E. & Krejcová, L. V. (2026). Dance therapy improves the joint range of motion in people with Parkinson’s disease: an essay with the Baila Parkinson method. Brazilian Journal of Motor Behavior, 20(1), Article e536. https://doi.org/10.20338/bjmb.v20i1.526

Møhlenberg, M., Jørgensen, S. E., Marije van der Sluis, R., Zillinger, T., Hinke, D. M., Hollensen, A. K., Hansen, A. L., Hausfater, P., Gorochov, G., Tubach, F., Ghosn, J., Laouenan, C., Storgaard, M., Holm, C. K., Su, H., Pérez de Diego, R., Pujol, A., Zhang, S.-Y., Zhang, Q. ... COVID Human Genetic Effort (2026). Defective RNA Polymerase III sensing of mitochondrial DNA in pulmonary epithelial cells impairs type I IFN immunity to SARS-CoV-2. Proceedings of the National Academy of Sciences of the United States of America, 123(12), Article e2522111123. https://doi.org/10.1073/pnas.2522111123

AlZaim, I., Hassan, M. N., Schröter, M., Mannino, L., Dragicevic, K., Sjogaard, M. B., Festa, J., Dokshokova, L., Weinbrenner, S., Tardajos Ayllon, B., Hansen, B., Rasmussen, R. K., Christensen, J. N., Wagman, O., Schipper, R., Cai, M., Dheedene, W., Bohn, A. B., Farup, J. ... Kalucka, J. (2026). Defining the vascular niche of human adipose tissue across metabolic states. Nature Metabolism, 8(3), 722-740. https://doi.org/10.1038/s42255-026-01475-2

Nakajima, R., Yamamoto, S., Kawamura, Y. K., Kitazawa, T., Kimura, M. & Kitazawa, Y. (2026). Design, Synthesis, and Evaluation of an Ammonium-Terminated Superchaotropic Boron Cluster: Effects on the Transmembrane Delivery of Neutral and Charged Cargos. Inorganic Chemistry, 65(18), 9728-9733. https://doi.org/10.1021/acs.inorgchem.5c05467

Kaewjua, K., Ferapontova, E. E. & Siangproh, W. (2026). Detection of hydrogen peroxide using hemin-PEI/MWCNT-modified screen-printed graphene electrodes: Toward feasibility in exhaled breath condensate. Electrochimica Acta, 545, Article 147742. https://doi.org/10.1016/j.electacta.2025.147742

López Mujica, M. E. J., Boonkaew, S., Christensen, N. L., Abildgaard Pedersen, M., Riegels Jørgensen, K., Holm Vendelbo, M. & Ferapontova, E. E. (2026). Differentiating borderline HER2-expressing and HER2-positive cancers from other subtypes using serum urokinase plasminogen activator. British Journal of Cancer. Advance online publication. https://doi.org/10.1038/s41416-026-03471-5

Kuhn, C. C., Chand, M. K., Todesca, S., Williams, K., Keidel, A., Garland, W., Jensen, T. H. & Conti, E. (2026). Direct coupling of the human nuclear exosome adaptors NEXT and PAXT with transcription termination and processing machineries. Nucleic Acids Research, 54(4), Article gkag088. https://doi.org/10.1093/nar/gkag088

Wyss, N., Riis, C., Karkov, H. S., Lund, S., Ferkinghoff-Borg, J., Wiberg, C. & Kjaergaard, M. (2026). Disentangling epitope spacing and antibody flexibility from avidity: A quantitative model for competition and bivalency in biosensor assays. Biophysical Journal, 125(13), 3214-3228. https://doi.org/10.1016/j.bpj.2026.04.025

Bornhofen, E., Mouritzen, T. W., Alves, S., Robertson-Shersby-Harvie, T. R., Skovbjerg, C. K., Windhorst, A., Zhang, H., Jayakody, T. B., Zhang, J., Nadzieja, M., Shim, H., Magnin-Robert, J.-B., Aubert, G., Floriot, M., Guiziou, C., Sass, O., Welna, G., Solís, I., Nielsen, L. K. ... Andersen, S. U. (2026). Dissecting the genetic basis of yield stability in faba bean by multi-environment analysis. Genome Biology, 27(1). https://doi.org/10.1186/s13059-026-04181-0

Plum-Jensen, L. E., Mohr, M. G., Tanabe, T. S., Wang, B., Echers, S. G., Madsen, N. S., Thorup, C., Linhartová, M., Nielsen, L. P., Dueholm, M. K. D., Boesen, T., Marshall, I. P. G., Dahl, C. & Schramm, A. (2026). Distribution of a novel DsrEFH sulfur transferase suggests widespread sulfur oxidation capacity in sulfate reducers. ISME Journal, 20(1), Article wrag130. https://doi.org/10.1093/ismejo/wrag130

López Hernández, M., Scavenius, C., Otzen, D. E. & Pedersen, J. S. (2026). Divergent effects of anionic surfactants on laundry enzymes: Structural stability, activity modulation, and self-cleavage mechanisms. International Journal of Biological Macromolecules, 335(1), Article 149069. https://doi.org/10.1016/j.ijbiomac.2025.149069

Nielsen, K. L., Lassen, J. K., Løber, I. M. M. M., Skovbo, F., Frisch, K., Czaja, T. P., Khakimov, B., Engelsen, S. B., Johannsen, M. & Villesen, P. (2026). Donor-Independent Metabolomics Enables Bloodstain Age Determination at Crime Scenes. Journal of Proteome Research, 25(7), 3671-3680. https://doi.org/10.1021/acs.jproteome.6c00199

Harazin, A., Reinert, L. S., Alam, P., Hoy, L., Marnow, A. B., Nielsen, J., Lorentzen, A., Otzen, D. E., Paludan, S. R. & Nielsen, M. S. (2026). Double-Stranded DNA Sensing cGAS-STING Immune Signaling in a Rat Co-Culture Model of the Blood-Brain Barrier. Cell Biochemistry and Function, 44(6), e70240. Article e70240. https://doi.org/10.1002/cbf.70240

Kjeldsen, M. H., Thorsteinsson, M., Fedosov, S., Børsting, C. F., Weisbjerg, M. R., Jensen, S. K., Lund, P. & Lashkari, S. (2026). Effect of different CH4 mitigation strategies on milk vitamins B2 and B12 concentrations. In Proceedings of the 13th Nordic Feed Science Conference, Uppsala, Sweden (pp. 104-106) https://www.slu.se/contentassets/7d83fe199a1d4d8caa250e503da3a7f9/proceedings-nordic-feed-science-conference-2026-tg.pdf

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ISEV workshop (2026). Biomolecular Corona of Extracellular Vesicles: Report on Isev Workshop. Journal of Extracellular Biology, 5(8), e70172. https://doi.org/10.1002/jex2.70172

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