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Peer-reviewed publications at MBG - 2025

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Nybo, T., Gamon, L. F., Fuentes-Lemus, E., Otzen, D. E., Davies, M. J. & Hägglund, P. (2025). Dimethyl labeling of N-terminal amines allows unambiguous identification of protein crosslinks. Free Radical Biology & Medicine, 227, 629-637. https://doi.org/10.1016/j.freeradbiomed.2024.12.002
Giagnoni, G., Foldager, L., Stephansen, R. B., Liu, H., Lassen, J. & Weisbjerg, M. R. (2025). Do feed conversion efficiency and its inverse, feed conversion ratio, differ in their distributions for dairy cows?. Abstract from 76th Annual Meeting of The European Federation of Animal Science, Innsbruck, Austria.
Novosylna, O., Shalak, V., Dąbrowska, K., Patmanidis, I., Lozhko, D., Bondarchuk, T., Schiøtt, B., Pedersen, J. S., Knudsen, C. R., Nissen, P., Dadlez, M. & Negrutskii, B. (2025). Dynamics and structural features of the eEF1A1 and eEF1A2 paralogs. Nucleic Acids Research, 53(21), Article gkaf1177. https://doi.org/10.1093/nar/gkaf1177
Bøtkjær, J. A., Poulsen, L. L. C., Noer, P. R., Grøndahl, M. L., Englund, A. L. M., Franks, S., Hardy, K., Oxvig, C. & Andersen, C. Y. (2025). Dynamics of IGF Signaling During the Ovulatory Peak in Women Undergoing Ovarian Stimulation. The Journal of clinical endocrinology and metabolism, 110(1), e160-e167. https://doi.org/10.1210/clinem/dgae132
Zhang, T., Bär, J., Risberg, L., Gómez Mejia, A., Hammar, H., Löffler, S., Otzen, D. E., Andreasen, M., Meyer, R. L., Melican, K., Zinkernagel, A. S. & Richter-Dahlfors, A. (2025). Dynamic visualization of extracellular matrix components in S. aureus colony biofilms reveals functional amyloids leading to the formation of cap-like structures. Biofilm, 10, Article 100318. https://doi.org/10.1016/j.bioflm.2025.100318
Asenjo-Martinez, A., Dragicevic, K., Hou, W. H., Ozsvar, A., Winther Hansen, N., Pfisterer, U., Rydbirk, R., Demharter, S., Møller, B. E., Gasthaus, J., Korshunova, I., Perrier, J. F., Capogna, M., Vasistha, N. A. & Khodosevich, K. (2025). Dysfunction of cortical GABAergic projection neurons as a major hallmark in a model of neuropsychiatric syndrome. Neuron, 113(19), 3204-3223. https://doi.org/10.1016/j.neuron.2025.08.028
Behrens, T., Balasubramanian, J., Secher, J. B.-M., Ivask, M., Kadarmideen, H. & Rabaglino, M. (2025). Effects of in vitro embryo production on the epigenomic profiles of day 15 bovine conceptus. Reproduction, Fertility and Development, 37(1), Article 114. https://doi.org/10.1071/RDv37n1Ab114
Garde, C., Pavlidis, M. A., Garces, P., Lange, E. J., Ramarathinam, S. H., Sokač, M., Pandey, K., Faridi, P., Ahrenfeldt, J., Chung, S., Friis, S., Kleine-Kohlbrecher, D., Birkbak, N. J., Kringelum, J. V., Rønø, B., Purcell, A. W. & Trolle, T. (2025). Endogenous viral elements constitute a complementary source of antigens for personalized cancer vaccines. NPJ vaccines, 10(1), Article 54. https://doi.org/10.1038/s41541-025-01107-y
Rasmussen, C. L. M., Frederiksen, S. F., Heegaard, C. W., Thomsen, M. S., Hede, E., Laczek, B., Körbelin, J., Wüstner, D., Thomsen, L. B., Schwaninger, M., Jensen, O. N., Moos, T. & Burkhart, A. (2025). Endothelial and neuronal engagement by AAV-BR1 gene therapy alleviates neurological symptoms and lipid deposition in a mouse model of Niemann-Pick type C2. Fluids and Barriers of the CNS, 22(1), Article 13. https://doi.org/10.1186/s12987-025-00621-4
Bontempi, D., Zalay, O., Bitterman, D. S., Birkbak, N., Shyr, D., Haugg, F., Qian, J. M., Roberts, H., Perni, S., Prudente, V., Pai, S., Dekker, A., Haibe-Kains, B., Guthier, C., Balboni, T., Warren, L., Krishan, M., Kann, B. H., Swanton, C. ... Aerts, H. J. W. L. (2025). FaceAge, a deep learning system to estimate biological age from face photographs to improve prognostication: a model development and validation study. The Lancet Digital Health, 7(6), Article 100870. https://doi.org/10.1016/j.landig.2025.03.002
Khachadourian, V., Arildskov, E. S., Grove, J., O'Reilly, P. F., Buxbaum, J. D., Reichenberg, A., Sandin, S., Croen, L. A., Schendel, D., Hansen, S. N. & Janecka, M. (2025). Familial confounding in the associations between maternal health and autism. Nature Medicine, 31(3), 996-1007. https://doi.org/10.1038/s41591-024-03479-5
Nielsen, T. T., Bali, P., Grove, J., Mohr-Jensen, C., Werge, T., Dalsgaard, S., Børglum, A. D., Sonuga-Barke, E., Minnis, H., Corfield, E. C., Tbartz van Elst, L., Mattheisen, M., de Wit, M. M., Uddin, M. J., Anney, R. J. L., Scherer, S. W., Bourgeron, T., Polderman, T. J. C., Autism Spectrum Working Group of the Psychiatric Genomics Consortium & Demontis, D. (2025). Genetic Architecture and Risk of Childhood Maltreatment Across 5 Psychiatric Diagnoses. JAMA Psychiatry, Article e0243639. Advance online publication. https://doi.org/10.1001/jamapsychiatry.2025.0828
Cabrejas-Olalla, A., Jørgensen, F. G., Cheng, J. Y., Kjærgaard, P. C., Schierup, M. H., Mailund, T. & Athanasiadis, G. (2025). Genetic predictions of eye and hair colour in the Danish population. Forensic Science International: Genetics, 78, Article 103267. https://doi.org/10.1016/j.fsigen.2025.103267
Garcia-Erill, G., Liu, S., Le, M. D., Hurley, M. M., Nguyen, H. D., Nguyen, D. Q., Nguyen, D. H., Santander, C. G., Sánchez Barreiro, F., Gomes Martins, N. F., Hanghøj, K., Salleh, F. M., Ramos-Madrigal, J., Wang, X., Sinding, M. H. S., Morales, H. E., Stæger, F. F., Wilkinson, N., Meng, G. ... Heller, R. (2025). Genomes of critically endangered saola are shaped by population structure and purging. Cell, 188(12), 3102-3116.e22. https://doi.org/10.1016/j.cell.2025.03.040
Strom, N. I., Gerring, Z. F., Galimberti, M., Yu, D., Halvorsen, M. W., Abdellaoui, A., Rodriguez-Fontenla, C., Sealock, J. M., Bigdeli, T., Coleman, J. R., Mahjani, B., Thorp, J. G., Bey, K., Burton, C. L., Luykx, J. J., Zai, G., Alemany, S., Andre, C., Askland, K. D. ... 23andMe Inc (2025). Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder. Nature Genetics, 57(6), 1389-1401. Article 230. https://doi.org/10.1038/s41588-025-02189-z
Strom, N. I., Halvorsen, M. W., Grove, J., Ásbjörnsdóttir, B., Luðvígsson, P., Thorarensen, Ó., de Schipper, E., Bäckmann, J., Andrén, P., Tian, C., Als, T. D., Nissen, J. B., Meier, S. M., Mattheisen, M., PGC TS Working Group & 23andMe Research Team (2025). Genome-Wide Association Study Meta-Analysis of 9619 Cases With Tic Disorders. Biological Psychiatry, 97(7), 743-752. https://doi.org/10.1016/j.biopsych.2024.07.025
Qin, Q., Wei, P., Usman, S., Ahamefule, C. S., Jin, C., Wang, B., Yan, K., van Aalten, D. M. F. & Fang, W. (2025). Gfa1 (glutamine fructose-6-phosphate aminotransferase) is essential for Aspergillus fumigatus growth and virulence. BMC Biology, 23(1), Article 80. https://doi.org/10.1186/s12915-025-02184-0
Jin, Z., Olsen, W. P., Mörman, C., Leppert, A., Kumar, R., Møllebjerg, A., Nielsen, L. G., Moshynets, O. V., Frasinyuk, M. S., Elosua, J. Y., Ferreira, D., Abelein, A., Landreh, M., Knight, S. D., Johansson, J., Otzen, D. E. & Chen, G. (2025). Helicobacter pylori CagA protein is a potent and broad-spectrum amyloid inhibitor. Science Advances, 11(24), Article eads7525. https://doi.org/10.1126/sciadv.ads7525
Li, Z., Xue, Y., Duan, Y., Yuan, W., Chen, C., Shi, S., Su, X. C., Kisiswa, L., Fan, J. S. & Lin, Z. (2025). Heterotypic interactions among members of the death domain superfamily with implications for p75NTR-mediated co-signaling. International Journal of Biological Macromolecules, 304(Part 1), Article 140791. https://doi.org/10.1016/j.ijbiomac.2025.140791
Teixeira, L. M. C., Paiva, P., Johansen, M. B., Sommerfeldt, A., Petersen, A. R., Rotilio, L., Sandahl, A., Morth, J. P., Westh, P., Otzen, D. E., Fernandes, P. A. & Ramos, M. J. (2025). Hydrolysis of the Urethane Bond Catalyzed by Pseudomonas sp. MIS38 Lipase: A QM/MM Mechanistic Insight. ACS Catalysis, 15, 14728-14740. https://doi.org/10.1021/acscatal.5c03228
Yamamoto, S., Nakajima, R., Hirai, Y., Kawamura, Y. K., Makita, Y., Kitazawa, T., Kimura, M. & Kitazawa, Y. (2025). Hydroxylated iodinated boron clusters: a tunable platform for enhanced membrane transport and biocompatibility. Chemical Communications. Advance online publication. https://doi.org/10.1039/d5cc04085j
Pareek, C. S., Sachajko, M., Kalra, G., Sultana, S., Szostak, A., Chalaskiewicz, K., Kepka-Borkowska, K., Poławska, E., Ogłuszka, M., Pierzchała, D., Starzyński, R., Taniguchi, H., Juszczuk-Kubiak, E., Lepczyński, A., Ślaska, B., Kozera, W., Czarnik, U., Wysocki, P., Kadarmideen, H. N. ... Pierzchała, M. (2025). Identification of trait-associated microRNA modules in liver transcriptome of pig fed with PUFAs-enriched supplementary diet. Journal of Applied Genetics, 66(2), 389-407. https://doi.org/10.1007/s13353-024-00912-w
TRACERx Consortium & Genomics England Consortium (2025). ImmuneLENS characterizes systemic immune dysregulation in aging and cancer. Nature Genetics, 57(3), 694-705. Article 305. https://doi.org/10.1038/s41588-025-02086-5
Dardani, C., Robinson, J. W., Jones, H. J., Rai, D., Stergiakouli, E., Grove, J., Gardner, R., McIntosh, A. M., Havdahl, A., Hemani, G., Davey Smith, G., Richardson, T. G., Gaunt, T. R. & Khandaker, G. M. (2025). Immunological drivers and potential novel drug targets for major psychiatric, neurodevelopmental, and neurodegenerative conditions. Molecular Psychiatry, 30(10), 4487-4496. Article e1004092. https://doi.org/10.1038/s41380-025-03032-x
Bruhn, D., Fan, Y., Griffin, K. L., Cowan-Turner, D., Scafaro, A. P., Møller, I. M. & Atkin, O. K. (2025). Importance of the leaf respiratory quotient. Physiologia Plantarum, 177(2), Article e70235. https://doi.org/10.1111/ppl.70235
Midtgaard, S. R., Hansen, M. S., Drachmann, N., Geng, X., Blans, K. I. M., Møbjerg, M. M. F., Frølund, A. F., Rasmussen, J. T. & Ostenfeld, M. S. (2025). Industrial Scale Production and Characterization of a Whey Fraction Enriched in Extracellular Vesicle Material. Journal of Extracellular Biology, 4(5), Article e70044. https://doi.org/10.1002/jex2.70044

Peer-reviewed publications at MBG - all years

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Sigurdsson, A. I., Gräf, J. F., Yang, Z., Ravn, K., Meisner, J., Thielemann, R., Webel, H., Smit, R. A. J., Niu, L., Mann, M., Vilhjalmsson, B., Neale, B. M., Holm, J.-C., Ganna, A., Hansen, T., Loos, R. J. F., Rasmussen, S. & FinnGen (2025). Complex genetic effects linked to plasma protein abundance in the UK Biobank. Nature Communications. Advance online publication. https://doi.org/10.1038/s41467-025-67235-0
Nguyen, M. T. A., Andersen, E. S. & Pothoulakis, G. (2025). Construction of Small Genes with Repetitive Elements Using Oligo Extension and Golden Gate Assembly. In D. Schindler (Ed.), Golden Gate Cloning (pp. 219-227). Humana Press. https://doi.org/10.1007/978-1-0716-4220-7_12
Sall, K. K., Foldager, L., Delf, C., Christensen, S. J., Agerley, M. N., Havn, K. T. & Pedersen, C. (2025). Control of neonatal diarrhea in piglets with reduced antibiotic use by application of a complementary feed - a randomized controlled farm trial. Veterinary Sciences, 12(1), Article 42. https://doi.org/10.3390/vetsci12010042
Horsdal, H. T., Albiñana, C., Zhu, Z., Boelt, S. G., Borbye-Lorenzen, N., Cohen, A. S., Skogstrand, K., Melgaard, L., MacSween, N. J., Thorbek, M. J., Plana-Ripoll, O., Petersen, L. V., Bulik, C. M., Børglum, A. D., Mors, O., Nordentoft, M., Werge, T., Moen, G.-H., D'Urso, S. ... McGrath, J. J. (2025). Convergent evidence linking neonatal vitamin D status and risk of neurodevelopmental disorders: a Danish case-cohort study. The Lancet Psychiatry, 12(6), 410-420. https://doi.org/10.1016/S2215-0366(25)00099-9
Zimmer, F., Fox, A. M., Pan, Q., Rühle, F., Andersen, P., Huylmans, A. K., Schwander, T., Basilicata, M. F. & Keller Valsecchi, C. I. (2025). Convergent evolution of H4K16ac-mediated dosage compensation in the ZW species Artemia franciscana. PLoS Genetics, 21(10), Article e1011895. https://doi.org/10.1371/journal.pgen.1011895
Marzookian, K., Aliakbari, F., Hourfar, H., Sabouni, F., Otzen, D. E. & Morshedi, D. (2025). Corrigendum to "The neuroprotective effect of human umbilical cord MSCs-derived secretome against α-synuclein aggregates on the blood-brain barrier" [Int. J. Biol. Macromol. Volume 290 (2025), 140387]. International Journal of Biological Macromolecules, Article 149909. Advance online publication. https://doi.org/10.1016/j.ijbiomac.2025.149909
Rashidi, A., Füchtbauer, E. M., Vahabzadeh, Z., Soleimani, F., Rahimi, K., Nikkhoo, B., Fakhari, S., Erfan, M. B. K., Azarnezhad, A., Pooladi, A., Soheili, F. & Fathi, F. (2025). CRISPR/Cas9-mediated knockout of DYRK1B in triple-negative breast cancer cells: implications for cell proliferation, apoptosis, and therapeutic sensitivity. Biochemical Engineering Journal, 213, Article 109553. https://doi.org/10.1016/j.bej.2024.109553
Luige, J., Conrad, T., Armaos, A., Louloupi, A., Vincent, A., Meierhofer, D., Gajhede, M., Tartaglia, G. G. & Ørom, U. A. V. (2025). Design and characterization of G-quadruplex RNA aptamers reveal RNA-binding by KDM5 lysine demethylases. Computational and Structural Biotechnology Journal, 27, 2719-2729. https://doi.org/10.1016/j.csbj.2025.06.027
Zhang, S., Ma, J., Riera Belles, M., Besenbacher, S., Niskanen, J. E., Salokorpi, N., Hundi, S., Hytönen, M. K., Zhou, T., Li, G.-M., Ostrander, E. A., Schierup, M. H., Lohi, H. & Wang, G.-D. (2025). Determinants of de novo mutations in extended pedigrees of 43 dog breeds. Genome Biology, 26(1), Article 305. https://doi.org/10.1186/s13059-025-03804-2
Thomsen, M. E., Bennike, T. B., Christiansen, G., Emmersen, J., Laursen, N. S., Zarantonello, A., Andersen, G. R., Liu, L., Dueholm, M. K. D., Opstrup, K. V., Stensballe, A. & Birkelund, S. (2025). Differences in complement activation of serum-resistant and serum-sensitive Klebsiella pneumoniae isolates. Molecular immunology, 183, 274-285. https://doi.org/10.1016/j.molimm.2025.05.014
Nybo, T., Gamon, L. F., Fuentes-Lemus, E., Otzen, D. E., Davies, M. J. & Hägglund, P. (2025). Dimethyl labeling of N-terminal amines allows unambiguous identification of protein crosslinks. Free Radical Biology & Medicine, 227, 629-637. https://doi.org/10.1016/j.freeradbiomed.2024.12.002
Giagnoni, G., Foldager, L., Stephansen, R. B., Liu, H., Lassen, J. & Weisbjerg, M. R. (2025). Do feed conversion efficiency and its inverse, feed conversion ratio, differ in their distributions for dairy cows?. Abstract from 76th Annual Meeting of The European Federation of Animal Science, Innsbruck, Austria.
Novosylna, O., Shalak, V., Dąbrowska, K., Patmanidis, I., Lozhko, D., Bondarchuk, T., Schiøtt, B., Pedersen, J. S., Knudsen, C. R., Nissen, P., Dadlez, M. & Negrutskii, B. (2025). Dynamics and structural features of the eEF1A1 and eEF1A2 paralogs. Nucleic Acids Research, 53(21), Article gkaf1177. https://doi.org/10.1093/nar/gkaf1177
Bøtkjær, J. A., Poulsen, L. L. C., Noer, P. R., Grøndahl, M. L., Englund, A. L. M., Franks, S., Hardy, K., Oxvig, C. & Andersen, C. Y. (2025). Dynamics of IGF Signaling During the Ovulatory Peak in Women Undergoing Ovarian Stimulation. The Journal of clinical endocrinology and metabolism, 110(1), e160-e167. https://doi.org/10.1210/clinem/dgae132
Zhang, T., Bär, J., Risberg, L., Gómez Mejia, A., Hammar, H., Löffler, S., Otzen, D. E., Andreasen, M., Meyer, R. L., Melican, K., Zinkernagel, A. S. & Richter-Dahlfors, A. (2025). Dynamic visualization of extracellular matrix components in S. aureus colony biofilms reveals functional amyloids leading to the formation of cap-like structures. Biofilm, 10, Article 100318. https://doi.org/10.1016/j.bioflm.2025.100318
Asenjo-Martinez, A., Dragicevic, K., Hou, W. H., Ozsvar, A., Winther Hansen, N., Pfisterer, U., Rydbirk, R., Demharter, S., Møller, B. E., Gasthaus, J., Korshunova, I., Perrier, J. F., Capogna, M., Vasistha, N. A. & Khodosevich, K. (2025). Dysfunction of cortical GABAergic projection neurons as a major hallmark in a model of neuropsychiatric syndrome. Neuron, 113(19), 3204-3223. https://doi.org/10.1016/j.neuron.2025.08.028
Behrens, T., Balasubramanian, J., Secher, J. B.-M., Ivask, M., Kadarmideen, H. & Rabaglino, M. (2025). Effects of in vitro embryo production on the epigenomic profiles of day 15 bovine conceptus. Reproduction, Fertility and Development, 37(1), Article 114. https://doi.org/10.1071/RDv37n1Ab114
Garde, C., Pavlidis, M. A., Garces, P., Lange, E. J., Ramarathinam, S. H., Sokač, M., Pandey, K., Faridi, P., Ahrenfeldt, J., Chung, S., Friis, S., Kleine-Kohlbrecher, D., Birkbak, N. J., Kringelum, J. V., Rønø, B., Purcell, A. W. & Trolle, T. (2025). Endogenous viral elements constitute a complementary source of antigens for personalized cancer vaccines. NPJ vaccines, 10(1), Article 54. https://doi.org/10.1038/s41541-025-01107-y
Rasmussen, C. L. M., Frederiksen, S. F., Heegaard, C. W., Thomsen, M. S., Hede, E., Laczek, B., Körbelin, J., Wüstner, D., Thomsen, L. B., Schwaninger, M., Jensen, O. N., Moos, T. & Burkhart, A. (2025). Endothelial and neuronal engagement by AAV-BR1 gene therapy alleviates neurological symptoms and lipid deposition in a mouse model of Niemann-Pick type C2. Fluids and Barriers of the CNS, 22(1), Article 13. https://doi.org/10.1186/s12987-025-00621-4
Bontempi, D., Zalay, O., Bitterman, D. S., Birkbak, N., Shyr, D., Haugg, F., Qian, J. M., Roberts, H., Perni, S., Prudente, V., Pai, S., Dekker, A., Haibe-Kains, B., Guthier, C., Balboni, T., Warren, L., Krishan, M., Kann, B. H., Swanton, C. ... Aerts, H. J. W. L. (2025). FaceAge, a deep learning system to estimate biological age from face photographs to improve prognostication: a model development and validation study. The Lancet Digital Health, 7(6), Article 100870. https://doi.org/10.1016/j.landig.2025.03.002
Khachadourian, V., Arildskov, E. S., Grove, J., O'Reilly, P. F., Buxbaum, J. D., Reichenberg, A., Sandin, S., Croen, L. A., Schendel, D., Hansen, S. N. & Janecka, M. (2025). Familial confounding in the associations between maternal health and autism. Nature Medicine, 31(3), 996-1007. https://doi.org/10.1038/s41591-024-03479-5
Nielsen, T. T., Bali, P., Grove, J., Mohr-Jensen, C., Werge, T., Dalsgaard, S., Børglum, A. D., Sonuga-Barke, E., Minnis, H., Corfield, E. C., Tbartz van Elst, L., Mattheisen, M., de Wit, M. M., Uddin, M. J., Anney, R. J. L., Scherer, S. W., Bourgeron, T., Polderman, T. J. C., Autism Spectrum Working Group of the Psychiatric Genomics Consortium & Demontis, D. (2025). Genetic Architecture and Risk of Childhood Maltreatment Across 5 Psychiatric Diagnoses. JAMA Psychiatry, Article e0243639. Advance online publication. https://doi.org/10.1001/jamapsychiatry.2025.0828
Cabrejas-Olalla, A., Jørgensen, F. G., Cheng, J. Y., Kjærgaard, P. C., Schierup, M. H., Mailund, T. & Athanasiadis, G. (2025). Genetic predictions of eye and hair colour in the Danish population. Forensic Science International: Genetics, 78, Article 103267. https://doi.org/10.1016/j.fsigen.2025.103267
Garcia-Erill, G., Liu, S., Le, M. D., Hurley, M. M., Nguyen, H. D., Nguyen, D. Q., Nguyen, D. H., Santander, C. G., Sánchez Barreiro, F., Gomes Martins, N. F., Hanghøj, K., Salleh, F. M., Ramos-Madrigal, J., Wang, X., Sinding, M. H. S., Morales, H. E., Stæger, F. F., Wilkinson, N., Meng, G. ... Heller, R. (2025). Genomes of critically endangered saola are shaped by population structure and purging. Cell, 188(12), 3102-3116.e22. https://doi.org/10.1016/j.cell.2025.03.040
Strom, N. I., Gerring, Z. F., Galimberti, M., Yu, D., Halvorsen, M. W., Abdellaoui, A., Rodriguez-Fontenla, C., Sealock, J. M., Bigdeli, T., Coleman, J. R., Mahjani, B., Thorp, J. G., Bey, K., Burton, C. L., Luykx, J. J., Zai, G., Alemany, S., Andre, C., Askland, K. D. ... 23andMe Inc (2025). Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder. Nature Genetics, 57(6), 1389-1401. Article 230. https://doi.org/10.1038/s41588-025-02189-z