Peer-reviewed articles

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Latest peer-reviewed publications at MBG

Peer-reviewed publications at MBG - all years

Catapano, C., Rahm, J. V., Omer, M., Teodori, L., Kjems, J., Dietz, M. S. & Heilemann, M. (2023). Biased activation of the receptor tyrosine kinase HER2. Cellular and Molecular Life Sciences, 80(6), Article 158. https://doi.org/10.1007/s00018-023-04806-8

Fernandez-Cantos, M. V., Garcia-Morena, D., Yi, Y., Liang, L., Gómez-Vázquez, E. & Kuipers, O. P. (2023). Bioinformatic mining for RiPP biosynthetic gene clusters in Bacteroidales reveals possible new subfamily architectures and novel natural products. Frontiers in Microbiology, 14, 1219272. Article 1219272. https://doi.org/10.3389/fmicb.2023.1219272

Pedersen, D. V., Gytz, H., Winkler, M. B. L., Zarantonello, A., Baumann, N., Hansen, A. G., Thiel, S., Andersen, G. R., Valerius, T. & Laursen, N. S. (2023). Bispecific Complement Engagers for Targeted Complement Activation. Journal of Immunology, 211(3), 403-413. https://doi.org/10.4049/jimmunol.2200952

Al-Sawaf, O., Weiss, J., Skrzypski, M., Lam, J. M., Karasaki, T., Zambrana, F., Kidd, A. C., Frankell, A. M., Watkins, T. B. K., Martínez-Ruiz, C., Puttick, C., Black, J. R. M., Huebner, A., Bakir, M. A., Collins, S., Veeriah, S., Magno, N., Naceur-Lombardelli, C., Prymas, P. ... TRACERx Consortium (2023). Body composition and lung cancer-associated cachexia in TRACERx. Nature Medicine, 29(4), 846-858. https://doi.org/10.1038/s41591-023-02232-8

Holm, S., Larsen, R. M., Holst, C. M., Heide-Jørgensen, M. P., Steffensen, J. F., Stevnsner, T. & Larsen, K. (2023). Bowhead NEIL1: molecular cloning, characterization, and enzymatic properties. Biochimie, 206, 136-149. https://doi.org/10.1016/j.biochi.2022.10.014

Lundby, J. M. B., Holste, S. & Pedersen, L. (2023). Brain Calcifications and Psychiatric Disorders. Abstract from 20th Annual Vienna BioCenter PhD Program Symposium, Vienna, Austria.

Boxy, P., Nykjær, A. & Kisiswa, L. (2023). Building better brains: the pleiotropic function of neurotrophic factors in postnatal cerebellar development. Frontiers in Molecular Neuroscience, 16, Article 1181397. https://doi.org/10.3389/fnmol.2023.1181397

Taleski, M., Chapman, K., Novák, O., Schmülling, T., Frank, M. & Djordjevic, M. A. (2023). CEP peptide and cytokinin pathways converge on CEPD glutaredoxins to inhibit root growth. Nature Communications, 14(1), Article 1683. https://doi.org/10.1038/s41467-023-37282-6

Rasmussen, C. B., Scavenius, C., Thøgersen, I. B., Harwood, S. L., Larsen, Ø., Bjerga, G. E. K., Stougaard, P., Enghild, J. J. & Thøgersen, M. S. (2023). Characterization of a novel cold-adapted intracellular serine protease from the extremophile Planococcus halocryophilus Or1. Frontiers in Microbiology, 14, Article 1121857. https://doi.org/10.3389/fmicb.2023.1121857

Berntsson, E., Vosough, F., Noormägi, A., Padari, K., Asplund, F., Gielnik, M., Paul, S., Jarvet, J., Tõugu, V., Roos, P. M., Kozak, M., Gräslund, A., Barth, A., Pooga, M., Palumaa, P. & Wärmländer, S. K. T. S. (2023). Characterization of Uranyl (UO₂²⁺) Ion Binding to Amyloid Beta (Aβ) Peptides: Effects on Aβ Structure and Aggregation. ACS Chemical Neuroscience, 14(15), 2618-2633. https://doi.org/10.1021/acschemneuro.3c00130

Lucotte, E. A., Guðmundsdóttir, V. B., Jensen, J. M., Skov, L., Macià, M. C., Almstrup, K., Schierup, M. H., Helgason, A. & Stefansson, K. (2023). Characterizing the evolution and phenotypic impact of ampliconic Y chromosome regions. Nature Communications, 14(1), Article 3990. https://doi.org/10.1038/s41467-023-39644-6

Tolomeo, D., Traversa, D., Venuto, S., Ebbesen, K., Garcia Rodriguez, J. L., Tamma, G., Ranieri, M., Simonetti, G., Ghetti, M., Paganelli, M., Visci, G., Liso, A., Kok, K., Muscarella, L. A., Fabrizio, F. P., Frassanito, M. A., Lamanuzzi, A., Saltarella, I., Solimando, A. G. ... Storlazzi, C. T. (2023). circPVT1 and PVT1/AKT3 show a role in cell proliferation, apoptosis, and tumor subtype-definition in Small Cell Lung Cancer. Genes, Chromosomes & Cancer, 62(7), 377-391. https://doi.org/10.1002/gcc.23121

Rasmussen, A. M., Okholm, T. L. H., Knudsen, M., Vang, S., Dyrskjøt, L., Hansen, T. B. & Pedersen, J. S. (2023). Circular stable intronic RNAs possess distinct biological features and are deregulated in bladder cancer. NAR cancer, 5(3), Article zcad041. https://doi.org/10.1093/narcan/zcad041

Martin, M., Nilsson, S. C., Eikrem, D., Fromell, K., Scavenius, C., Vogt, L. M., Bielecka, E., Potempa, J., Enghild, J. J., Nilsson, B., Ekdahl, K. N., Kapetanovic, M. C. & Blom, A. M. (2023). Citrullination of C1-inhibitor as a mechanism of impaired complement regulation in rheumatoid arthritis. Frontiers in Immunology, 14, Article 1203506. https://doi.org/10.3389/fimmu.2023.1203506

Zhang, B. L., Chen, W., Wang, Z., Pang, W., Luo, M. T., Wang, S., Shao, Y., He, W. Q., Deng, Y., Zhou, L., Chen, J., Yang, M. M., Wu, Y., Wang, L., Fernández-Bellon, H., Molloy, S., Meunier, H., Wanert, F., Kuderna, L. ... Wu, D. D. (2023). Comparative genomics reveals the hybrid origin of a macaque group. Science Advances, 9(22), Article eadd3580. https://doi.org/10.1126/sciadv.add3580

Busato, S., Gordon, M., Chaudhari, M., Thorsgaard Jensen, I., Akyol, T. Y., Andersen, S. U. & Williams, C. (2023). Compositionality, sparsity, spurious heterogeneity, and other data-driven challenges for machine learning algorithms within plant microbiome studies. Current Opinion in Plant Biology, 71, Article 102326. https://doi.org/10.1016/j.pbi.2022.102326

Zhang, Y., Plesner, T. J., Ouyang, Y., Zheng, Y.-C., Bouhier, E., Ingemann Berentzen, E., Zhang, M., Zhou, P., Zimmermann , W., Andersen, G. R. & Guo, Z. (2023). Computer-aided discovery of a novel thermophilic laccase for low-density polyethylene degradation. Journal of Hazardous Materials, 458, Article 131986. https://doi.org/10.1016/j.jhazmat.2023.131986

Afonine, P. V., Gobet, A., Moissonnier, L., Martin, J., Poon, B. K. & Chaptal, V. (2023). Conformational space exploration of cryo-EM structures by variability refinement. Biochimica et biophysica acta - Biomembranes, 1865(4), 184133. Article 184133. https://doi.org/10.1016/j.bbamem.2023.184133

Jensen, R. K., Pihl, R., Gadeberg, T. A. F., Jensen, J. K., Andersen, K. R., Thiel, S., Laursen, N. S. & Andersen, G. R. (2023). Correction: A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement (Journal of Biological Chemistry (2018) 293(17) (6269–6281), (S0021925820397313), (10.1074/jbc.RA117.001179)). The Journal of Biological Chemistry, 299(2), Article 102951. https://doi.org/10.1016/j.jbc.2023.102951

André, A. A. M., Yewdall, N. A. & Spruijt, E. (2023). Crowding-induced phase separation and gelling by co-condensation of PEG in NPM1-rRNA condensates. Biophysical Journal, 122(2), 397-407. https://doi.org/10.1016/j.bpj.2022.12.001

Sigurdsson, A. I., Louloudis, I., Banasik, K., Westergaard, D., Winther, O., Lund, O., Ostrowski, S. R., Erikstrup, C., Pedersen, O. B. V., Nyegaard, M., Brunak, S., Vilhjálmsson, B. J., Rasmussen, S. & DBDS Genomic Consortium (2023). Deep integrative models for large-scale human genomics. Nucleic Acids Research, 51(12), E67. Article e67. https://doi.org/10.1093/nar/gkad373

Zhang, C., Reid, K., Sands, A. F., Fraimout, A., Schierup, M. H. & Merilä, J. (2023). De Novo Mutation Rates in Sticklebacks. Molecular Biology and Evolution, 40(9), Article msad192. https://doi.org/10.1093/molbev/msad192

Als, T. D., Kurki, M. I., Grove, J., Voloudakis, G., Therrien, K., Tasanko, E., Nielsen, T. T., Naamanka, J., Veerapen, K., Levey, D. F., Bendl, J., Bybjerg-Grauholm, J., Zeng, B., Demontis, D., Rosengren, A., Athanasiadis, G., Bækved-Hansen, M., Qvist, P., Bragi Walters, G. ... Børglum, A. D. (2023). Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses. Nature Medicine, 29(7), 1832-1844. https://doi.org/10.1038/s41591-023-02352-1

Larsen, K. E. & Callesen, H. (2023). Developmental expression of CREB1 and NFATC2 in pig embryos. Molecular Biology Reports, 50(7), 6265-6271. https://doi.org/10.1007/s11033-023-08501-6

Olesen, H. G., Michailidou, I., Zelek, W. M., Vreijling, J., Ruizendaal, P., de Klein, F., Marquart, J. A., Kuipers, T. B., Mei, H., Zhang, Y., Ahasan, M., Johnson, K. K., Wang, Y., Morgan, B. P., van Dijk, M., Fluiter, K., Andersen, G. R. & Baas, F. (2023). Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex. Journal of Innate Immunity, 15(1), 16-36. https://doi.org/10.1159/000524587

Frank, M. & Reid, D. (2023). Dissecting symbiosis cell-by-cell. Molecular Plant, 16(2), 308-309. https://doi.org/10.1016/j.molp.2022.12.023

Skakkebæk, A., Kjær-Sørensen, K., Matchkov, V. V., Christensen, L. L., Just, J., Cömert, C., Andersen, N. H., Oxvig, C. & Gravholt, C. H. (2023). Dosage of the pseudoautosomal gene SLC25A6 is implicated in QTc interval duration. Scientific Reports, 13(1), Article 12089. https://doi.org/10.1038/s41598-023-38867-3

Christensen, M. H., Drue, S. O., Rasmussen, M. H., Frydendahl, A., Lyskjær, I., Demuth, C., Nors, J., Gotschalck, K. A., Iversen, L. H., Andersen, C. L. & Pedersen, J. S. (2023). Dreams: deep read-level error model for sequencing data applied to low-frequency variant calling and circulating tumor DNA detection. Genome Biology, 24(1), 99. Article 99. https://doi.org/10.1186/s13059-023-02920-1

Somavarapu, A. K., Kleijwegt, G., Nagaraj, M., Alam, P., Nielsen, J. & Otzen, D. E. (2023). Drug repurposing screens identify compounds that inhibit α-synuclein oligomers' membrane disruption and block antibody interactions. Chemical Science, 14(11), 3030-3047. https://doi.org/10.1039/d2sc05534a

Polák, P., Garland, W., Rathore, O., Schmid, M., Salerno-Kochan, A., Jakobsen, L., Gockert, M., Gerlach, P., Silla, T., Andersen, J. S., Conti, E. & Jensen, T. H. (2023). Dual agonistic and antagonistic roles of ZC3H18 provide for co-activation of distinct nuclear RNA decay pathways. Cell Reports, 42(11), Article 113325. https://doi.org/10.1016/j.celrep.2023.113325

Zelikin, A. N., Andersen, E. S. & Städler, B. (2023). Editorial for the Special Issue 'Synthetic Biology and Biomimicry'. Small, 19(13), Article 2301160. https://doi.org/10.1002/smll.202301160

Osório, C., Watt, A. & Kisiswa, L. (2023). Editorial: Molecular mechanisms and pathways in cerebellar function. Frontiers in Molecular Neuroscience, 16, Article 1258215. https://doi.org/10.3389/fnmol.2023.1258215

Jensen, M. B., Franchi, G. A., Larsen, M., Foldager, L. & Herskin, M. S. (2023). Effects of feed energy density, daily milking frequency, and a single injection of cabergoline on behavior and welfare in dairy cows at dry-off. Journal of Dairy Science, 106(12), 9136-9149. https://doi.org/10.3168/jds.2022-22835

Hernández-Castellano, L. E., Sørensen, M. T., Foldager, L., Herskin, M. S., Gross, J. J., Bruckmaier, R. M. & Larsen, M. (2023). Effects of feeding level, milking frequency, and single injection of cabergoline on blood metabolites, hormones, and minerals around dry-off in dairy cows. Journal of Dairy Science, 106(4), 2919-2932. https://doi.org/10.3168/jds.2022-22648

Kobek-Kjeldager, C., Jensen, L. D., Foldager, L., Thodberg, K., Petersen, D. L. S. & Herskin, M. S. (2023). Effects of journey duration and temperature during pre-slaughter transport on behaviour of cull sows in lairage. Research in Veterinary Science, 164, Article 105016. https://doi.org/10.1016/j.rvsc.2023.105016

Heger, T., Stock, C., Laursen, M. J., Habeck, M., Dieudonné, T. & Nissen, P. (2023). eGFP as an All-in-One Tag for Purification of Membrane Proteins. In Methods in Molecular Biology (Vol. 2652, pp. 171-186). Humana Press. https://doi.org/10.1007/978-1-0716-3147-8_9

Zhou, Y., Zhan, X., Jin, J., Zhou, L., Bergman, J., Li, X., Rousselle, M. M. C., Belles, M. R., Zhao, L., Fang, M., Chen, J., Fang, Q., Kuderna, L., Marques-Bonet, T., Kitayama, H., Hayakawa, T., Yao, Y. G., Yang, H., Cooper, D. N. ... Zhang, G. (2023). Eighty million years of rapid evolution of the primate Y chromosome. Nature Ecology & Evolution, 7(7), 1114-1130. https://doi.org/10.1038/s41559-022-01974-x

Roeters, S. J., Strunge, K., Pedersen, K. B., Golbek, T. W., Bregnhøj, M., Zhang, Y., Wang, Y., Dong, M., Nielsen, J., Otzen, D. E., Schiøtt, B. & Weidner, T. (2023). Elevated concentrations cause upright alpha-synuclein conformation at lipid interfaces. Nature Communications, 14(1), Article 5731. https://doi.org/10.1038/s41467-023-39843-1

Bohr, F., Bohr, S. S. R., Mishra, N. K., González-Foutel, N. S., Pinholt, H. D., Wu, S., Nielsen, E. M., Zhang, M., Kjaergaard, M., Jensen, K. J. & Hatzakis, N. S. (2023). Enhanced hexamerization of insulin via assembly pathway rerouting revealed by single particle studies. Communications Biology, 6(1), Article 178. https://doi.org/10.1038/s42003-022-04386-6

Maimaitili, M., Chen, M., Febbraro, F., Ucuncu, E., Kelly, R., Niclis, J. C., Christiansen, J. R., Mermet-Joret, N., Niculescu, D., Lauritsen, J., Iannielli, A., Klæstrup, I. H., Jensen, U. B., Qvist, P., Nabavi, S., Broccoli, V., Nykjær, A., Romero-Ramos, M. & Denham, M. (2023). Enhanced production of mesencephalic dopaminergic neurons from lineage-restricted human undifferentiated stem cells. Nature Communications, 14(1), Article 7871. https://doi.org/10.1038/s41467-023-43471-0

Aizawa, E., Ozonov, E. A., Kawamura, Y. K., Dumeau, C.-E., Nagaoka, S., Kitajima, T. S., Saitou, M., Peters, A. H. & Wutz, A. (2023). Epigenetic regulation limits competence of pluripotent stem cell-derived oocytes. The EMBO Journal, 42(23), e113955. Article e113955. https://doi.org/10.15252/embj.2023113955

Rasmussen, M. Q., Tindbæk, G., Nielsen, M. M., Merrild, C., Steiniche, T., Pedersen, J. S., Moestrup, S. K., Degn, S. E. & Madsen, M. (2023). Epigenetic Silencing of LRP2 Is Associated with Dedifferentiation and Poor Survival in Multiple Solid Tumor Types. Cancers, 15(6), Article 1830. https://doi.org/10.3390/cancers15061830

Rheinbay, E., Nielsen, M. M., Abascal, F., Wala, J. A., Shapira, O., Tiao, G., Hornshøj, H., Hess, J. M., Juul, R. I., Lin, Z., Feuerbach, L., Sabarinathan, R., Madsen, T., Kim, J., Mularoni, L., Shuai, S., Lanzós, A., Herrmann, C., Maruvka, Y. E. ... PCAWG Drivers and Functional Interpretation Working Group (2023). Erratum: Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes (Nature (2020) 578 7793 (102-111)). Nature, 614(7948), E40. https://doi.org/10.1038/s41586-022-05599-9

Karasaki, T., Moore, D. A., Veeriah, S., Naceur-Lombardelli, C., Toncheva, A., Magno, N., Ward, S., Bakir, M. A., Watkins, T. B. K., Grigoriadis, K., Huebner, A., Hill, M. S., Frankell, A. M., Abbosh, C., Puttick, C., Zhai, H., Gimeno-Valiente, F., Saghafinia, S., Kanu, N. ... TRACERx Consortium (2023). Evolutionary characterization of lung adenocarcinoma morphology in TRACERx. Nature Medicine, 29(4), 833-845. https://doi.org/10.1038/s41591-023-02230-w

Cullimore, J., Fliegmann, J., Gasciolli, V., Gibelin-Viala, C., Carles, N., Luu, T. B., Girardin, A., Cumener, M., Maillet, F., Pradeau, S., Fort, S., Bono, J. J., Gough, C. & Lefebvre, B. (2023). Evolution of Lipochitooligosaccharide Binding to a LysM-RLK for Nodulation in Medicago truncatula. Plant and Cell Physiology, 64(7), 746-757. https://doi.org/10.1093/pcp/pcad033

Bergeron, L. A., Besenbacher, S., Zheng, J., Li, P., Bertelsen, M. F., Quintard, B., Hoffman, J. I., Li, Z., St. Leger, J., Shao, C., Stiller, J., Gilbert, M. T. P., Schierup, M. H. & Zhang, G. (2023). Evolution of the germline mutation rate across vertebrates. Nature, 615(7951), 285-291. https://doi.org/10.1038/s41586-023-05752-y

Skov, L., Coll Macià, M., Lucotte, E. A., Cavassim, M. I. A., Castellano, D., Schierup, M. H. & Munch, K. (2023). Extraordinary selection on the human X chromosome associated with archaic admixture. Cell Genomics, 3(3), Article 100274. https://doi.org/10.1016/j.xgen.2023.100274

Rasmussen, H. Ø., Kumar, A., Shin, B., Stylianou, F., Sewell, L., Xu, Y., Otzen, D. E., Pedersen, J. S. & Matthews, S. J. (2023). FapA is an Intrinsically Disordered Chaperone for Pseudomonas Functional Amyloid FapC. Journal of Molecular Biology, 435(2), Article 167878. https://doi.org/10.1016/j.jmb.2022.167878