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Peer-reviewed publications at MBG - 2025

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Otzen, D. E., Peña-Díaz, S., Widmann, J., Daugberg, A. O. H., Zhang, Z., Jiang, Y., Mittal, C., Dueholm, M. K. D., Louros, N., Wang, H. & Javed, I. (2025). Interactions between pathological and functional amyloid: A match made in Heaven or Hell? Molecular Aspects of Medicine, 103, 101351. Article 101351. https://doi.org/10.1016/j.mam.2025.101351
Yu, X., Liu, C. D., Shen, S., Kim, E. S., Liu, Z., Zhang, H., Sun, N., Liu, Y., Martensen, P. M., Huang, Y. & Guo, H. (2025). Interferon alpha-inducible protein 27 (IFI27) inhibits hepatitis B virus (HBV) transcription through downregulating cellular transcription factor C/EBPα. Journal of Virology, 99(11), e0150925. https://doi.org/10.1128/jvi.01509-25
Mohr, M., Kozikowska, J., Petryszyn, Z., Ostrowska, K., Golusińska-Kardach, E., Golusiński, W., Suchorska, W. & Kulcenty, K. (2025). Interplay between hypoxia, RNA methylation, and HPV in head and neck squamous cell carcinomas: drivers of oncogenesis and resistance to therapy . EXCLI Journal, 24, 1767-1796. https://doi.org/10.17179/excli2025-8834
Garcia-Morena, D., Fernandez-Cantos, M. V., Escalera, S. L., Lok, J., Iannone, V., Cancellieri, P., Maathuis, W., Panagiotou, G., Aranzamendi, C., Aidy, S. E., Kolehmainen, M., El-Nezami, H., Wellejus, A. & Kuipers, O. P. (2025). In Vitro Influence of Specific Bacteroidales Strains on Gut and Liver Health Related to Metabolic Dysfunction-Associated Fatty Liver Disease. Probiotics and antimicrobial proteins, 17(3), 1498-1512. Article 101314. https://doi.org/10.1007/s12602-024-10219-1
Behrens, T., Balasubramanian, J., Ivask, M., Nõmm, M., Kavak, A., Secher, J. B.-M., Kadarmideen, H. N. & Rabaglino, M. B. (2025). In vitro processes alter the embryonic disc epigenome and transcriptome in the pre-implantation elongated bovine embryo. Biology of Reproduction, Article ioaf095. Advance online publication. https://doi.org/10.1093/biolre/ioaf095
Morin, M., Yin, W., MacLean, H., Devlin, B., Reichenberg, A., Swan, S. H., Buxbaum, J. D., Schendel, D., Persson, M., Laursen, T. M., Kolevzon, A., Grove, J., Klei, L., Roeder, K. & Sandin, S. (2025). Maternal body mass index in early pregnancy and autism in offspring: a population-based cohort study in Sweden and Denmark. BMC Medicine, 23(1), Article 620. https://doi.org/10.1186/s12916-025-04487-z
Sarrette, B., Luu, T. B., Johansson, A., Fliegmann, J., Pouzet, C., Pichereaux, C., Remblière, C., Sauviac, L., Carles, N., Amblard, E., Guyot, V., Bonhomme, M., Cullimore, J., Gough, C., Jacquet, C. & Pauly, N. (2025). Medicago truncatula SOBIR1 controls pathogen immunity and specificity in the Rhizobium-legume symbiosis. Plant, Cell and Environment, 48(1), 32-50. https://doi.org/10.1111/pce.15071
Jiang, Y., Wang, D., Zeng, S., Zhang, Y., Jiang, L., Pourmirzaei, M., Manshour, N., Esmaili, F., Zhang, W., Møller, I. M. & Xu, D. (2025). MULoc-target: Targeting peptide classification and detection using a protein language model. Briefings in bioinformatics, 26(4), Article bbaf436. https://doi.org/10.1093/bib/bbaf436
da Fonseca Junior, A. M., Ispada, J., de Lima , C. B., Trabuco do Amaral, D., Juan Ross, P., Kadarmideen, H. & Pecora Milazzoto, M. (2025). Multiomics integration uncovers metabolic control of H3K27ac in bovine inner cell masses. Biology of Reproduction, 1-10.
Bryzek, D., Gasiorek, A., Kowalczyk, D., Santocki, M., Ciaston, I., Dobosz, E., Kolaczkowska, E., Kjøge, K., Kantyka, T., Lech, M., Potempa, B., Enghild, J. J., Potempa, J. & Koziel, J. (2025). Non-classical neutrophil extracellular traps induced by PAR2-signaling proteases. Cell Death & Disease, 16(1), Article 109. https://doi.org/10.1038/s41419-025-07428-z
Talay, A., Belikov, A. V., To, P. K. P., Alfatemi, H. H., Alon, U., Deelen, J., Ewald, C. Y., Gems, D., Gorbunova, V., Gruber, J., Hägg, S., Hemming, J., Horvath, S., Kaya, A., Lewis, C. J., Maier, A. B., Marinova, M. B., Pawelec, G., Peleg, S. ... de Magalhães, J. P. (2025). Open problems in ageing science: a roadmap for biogerontology. GeroScience. Advance online publication. https://doi.org/10.1007/s11357-025-01964-4
Mirab, F., Pirhaghi, M., Otzen, D. E. & Saboury, A. A. (2025). Parkinson's disease and gut microbiota metabolites: The dual impact of vitamins and functional amyloids. B B A - Molecular Basis of Disease, 1871(6), Article 167862. https://doi.org/10.1016/j.bbadis.2025.167862
Waligórska, I., Żak, K. M., Mikrut, N., Budziaszek, J., Medviediev, V., Bielecka, E., Kantyka, T., Kozieł, J., Thøgersen, I. B., Enghild, J. J., Grudnik, P., Potempa, J. & Książek, M. (2025). Periodontopathogens degrade angiotensin I from the human renin-angiotensin system through surface-attached proteases. Scientific Reports, 15(1), Article 43309. https://doi.org/10.1038/s41598-025-27891-0
Schlosser, A., Pilecki, B., Allen, C., Benest, A. V., Lynch, A. P., Hua, J., Ved, N., Blackley, Z., Andersen, T. L., Hennig, D., Graversen, J. H., Möller, S., Skallerup, S., Ormhøj, M., Lange, C., Agostini, H. T., Grauslund, J., Heegaard, S., Dacheva, I. ... Sorensen, G. L. (2025). Pharmacological blocking of microfibrillar-associated protein 4 reduces retinal neoangiogenesis and vascular leakage. Molecular Therapy, 33(3), 1048-1072. https://doi.org/10.1016/j.ymthe.2025.01.038
Jansen, S. A. H., Dreyer, L. S. A., van Basten, J., Yao, Y., Otzen, D. E., de Greef, T. F. A., Knowles, T. P. J., Meijer, E. W. & Erkamp, N. A. (2025). PhaseXplorer Creates High-Dimensional Phase Diagrams with Closed-Loop Active Learning. ACS Nano, 19(45), 38981-38989. https://doi.org/10.1021/acsnano.5c07268
Zhang, X., Grove, J., Gu, Y., Buus, C. K., Nielsen, L. K., Neufeld, S. A. S., Koko, M., Malawsky, D. S., Wade, E. M., Verhoef, E., Gui, A., Hegemann, L., Geschwind, D. H., Wray, N. R., Havdahl, A., Ronald, A., St Pourcain, B., Robinson, E. B., Bourgeron, T. ... APEX consortium (2025). Polygenic and developmental profiles of autism differ by age at diagnosis. Nature, 646(8087), 1146-1155. https://doi.org/10.1038/s41586-025-09542-6
Smit, R. A. J., Wade, K. H., Hui, Q., Arias, J. D., Yin, X., Christiansen, M. R., Yengo, L., Preuss, M. H., Nakabuye, M., Rocheleau, G., Graham, S. E., Buchanan, V. L., Chittoor, G., Graff, M., Guindo-Martínez, M., Lu, Y., Marouli, E., Sakaue, S., Spracklen, C. N. ... VA Million Veteran Program (2025). Polygenic prediction of body mass index and obesity through the life course and across ancestries. Nature Medicine, 31(9), 3151-3168. https://doi.org/10.1038/s41591-025-03827-z
Henches, L., Kim, J., Yang, Z., Rubinacci, S., Pires, G., Albiñana, C., Boetto, C., Julienne, H., Frouin, A., Auvergne, A., Suzuki, Y., Djebali, S., Delaneau, O., Ganna, A., Vilhjálmsson, B., Privé, F. & Aschard, H. (2025). Polygenic risk score prediction accuracy convergence. Human Genetics and Genomics Advances, 6(3), Article 100457. https://doi.org/10.1016/j.xhgg.2025.100457
Martín-Rivada, Á., Martos-Moreno, G., Guerra-Cantera, S., Campillo-Calatayud, A., Oxvig, C., Frystyk, J., Chowen, J. A., Barrios, V. & Argente, J. (2025). Prepubertal Children With Obesity Have High Free IGF-1 Levels and Accelerated Growth Despite Reduced Pappalysin Levels. Journal of Clinical Endocrinology and Metabolism, 110(3), e622-e629. https://doi.org/10.1210/clinem/dgae288
Kawamura, Y. K., Ozonov, E. A., Papasaikas, P., Kondo, T., Nguyen, N. V., Stadler, M. B., Smallwood, S. A., Koseki, H. & Peters, A. H. F. M. (2025). Preventing CpG hypermethylation in oocytes safeguards mouse development. Developmental Cell, 60(23), 3285-3303.e9. https://doi.org/10.1016/j.devcel.2025.08.005
Ismail, S., Kubíková, J., Maichel, M., Andersen, P. & Jeske, M. (2025). Probing direct interactions between nuclear proteins in cells with nxReLo. Proceedings of the National Academy of Sciences of the United States of America, 122(48), Article e2518711122. https://doi.org/10.1073/pnas.2518711122

Peer-reviewed publications at MBG - all years

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Strom, N. I., Halvorsen, M. W., Grove, J., Ásbjörnsdóttir, B., Luðvígsson, P., Thorarensen, Ó., de Schipper, E., Bäckmann, J., Andrén, P., Tian, C., Als, T. D., Nissen, J. B., Meier, S. M., Mattheisen, M., PGC TS Working Group & 23andMe Research Team (2025). Genome-Wide Association Study Meta-Analysis of 9619 Cases With Tic Disorders. Biological Psychiatry, 97(7), 743-752. https://doi.org/10.1016/j.biopsych.2024.07.025
Qin, Q., Wei, P., Usman, S., Ahamefule, C. S., Jin, C., Wang, B., Yan, K., van Aalten, D. M. F. & Fang, W. (2025). Gfa1 (glutamine fructose-6-phosphate aminotransferase) is essential for Aspergillus fumigatus growth and virulence. BMC Biology, 23(1), Article 80. https://doi.org/10.1186/s12915-025-02184-0
Jin, Z., Olsen, W. P., Mörman, C., Leppert, A., Kumar, R., Møllebjerg, A., Nielsen, L. G., Moshynets, O. V., Frasinyuk, M. S., Elosua, J. Y., Ferreira, D., Abelein, A., Landreh, M., Knight, S. D., Johansson, J., Otzen, D. E. & Chen, G. (2025). Helicobacter pylori CagA protein is a potent and broad-spectrum amyloid inhibitor. Science Advances, 11(24), Article eads7525. https://doi.org/10.1126/sciadv.ads7525
Li, Z., Xue, Y., Duan, Y., Yuan, W., Chen, C., Shi, S., Su, X. C., Kisiswa, L., Fan, J. S. & Lin, Z. (2025). Heterotypic interactions among members of the death domain superfamily with implications for p75NTR-mediated co-signaling. International Journal of Biological Macromolecules, 304(Part 1), Article 140791. https://doi.org/10.1016/j.ijbiomac.2025.140791
Teixeira, L. M. C., Paiva, P., Johansen, M. B., Sommerfeldt, A., Petersen, A. R., Rotilio, L., Sandahl, A., Morth, J. P., Westh, P., Otzen, D. E., Fernandes, P. A. & Ramos, M. J. (2025). Hydrolysis of the Urethane Bond Catalyzed by Pseudomonas sp. MIS38 Lipase: A QM/MM Mechanistic Insight. ACS Catalysis, 15, 14728-14740. https://doi.org/10.1021/acscatal.5c03228
Yamamoto, S., Nakajima, R., Hirai, Y., Kawamura, Y. K., Makita, Y., Kitazawa, T., Kimura, M. & Kitazawa, Y. (2025). Hydroxylated iodinated boron clusters: a tunable platform for enhanced membrane transport and biocompatibility. Chemical Communications. Advance online publication. https://doi.org/10.1039/d5cc04085j
Pareek, C. S., Sachajko, M., Kalra, G., Sultana, S., Szostak, A., Chalaskiewicz, K., Kepka-Borkowska, K., Poławska, E., Ogłuszka, M., Pierzchała, D., Starzyński, R., Taniguchi, H., Juszczuk-Kubiak, E., Lepczyński, A., Ślaska, B., Kozera, W., Czarnik, U., Wysocki, P., Kadarmideen, H. N. ... Pierzchała, M. (2025). Identification of trait-associated microRNA modules in liver transcriptome of pig fed with PUFAs-enriched supplementary diet. Journal of Applied Genetics, 66(2), 389-407. https://doi.org/10.1007/s13353-024-00912-w
TRACERx Consortium & Genomics England Consortium (2025). ImmuneLENS characterizes systemic immune dysregulation in aging and cancer. Nature Genetics, 57(3), 694-705. Article 305. https://doi.org/10.1038/s41588-025-02086-5
Dardani, C., Robinson, J. W., Jones, H. J., Rai, D., Stergiakouli, E., Grove, J., Gardner, R., McIntosh, A. M., Havdahl, A., Hemani, G., Davey Smith, G., Richardson, T. G., Gaunt, T. R. & Khandaker, G. M. (2025). Immunological drivers and potential novel drug targets for major psychiatric, neurodevelopmental, and neurodegenerative conditions. Molecular Psychiatry, 30(10), 4487-4496. Article e1004092. https://doi.org/10.1038/s41380-025-03032-x
Bruhn, D., Fan, Y., Griffin, K. L., Cowan-Turner, D., Scafaro, A. P., Møller, I. M. & Atkin, O. K. (2025). Importance of the leaf respiratory quotient. Physiologia Plantarum, 177(2), Article e70235. https://doi.org/10.1111/ppl.70235
Midtgaard, S. R., Hansen, M. S., Drachmann, N., Geng, X., Blans, K. I. M., Møbjerg, M. M. F., Frølund, A. F., Rasmussen, J. T. & Ostenfeld, M. S. (2025). Industrial Scale Production and Characterization of a Whey Fraction Enriched in Extracellular Vesicle Material. Journal of Extracellular Biology, 4(5), Article e70044. https://doi.org/10.1002/jex2.70044
Otzen, D. E., Peña-Díaz, S., Widmann, J., Daugberg, A. O. H., Zhang, Z., Jiang, Y., Mittal, C., Dueholm, M. K. D., Louros, N., Wang, H. & Javed, I. (2025). Interactions between pathological and functional amyloid: A match made in Heaven or Hell? Molecular Aspects of Medicine, 103, 101351. Article 101351. https://doi.org/10.1016/j.mam.2025.101351
Yu, X., Liu, C. D., Shen, S., Kim, E. S., Liu, Z., Zhang, H., Sun, N., Liu, Y., Martensen, P. M., Huang, Y. & Guo, H. (2025). Interferon alpha-inducible protein 27 (IFI27) inhibits hepatitis B virus (HBV) transcription through downregulating cellular transcription factor C/EBPα. Journal of Virology, 99(11), e0150925. https://doi.org/10.1128/jvi.01509-25
Mohr, M., Kozikowska, J., Petryszyn, Z., Ostrowska, K., Golusińska-Kardach, E., Golusiński, W., Suchorska, W. & Kulcenty, K. (2025). Interplay between hypoxia, RNA methylation, and HPV in head and neck squamous cell carcinomas: drivers of oncogenesis and resistance to therapy . EXCLI Journal, 24, 1767-1796. https://doi.org/10.17179/excli2025-8834
Garcia-Morena, D., Fernandez-Cantos, M. V., Escalera, S. L., Lok, J., Iannone, V., Cancellieri, P., Maathuis, W., Panagiotou, G., Aranzamendi, C., Aidy, S. E., Kolehmainen, M., El-Nezami, H., Wellejus, A. & Kuipers, O. P. (2025). In Vitro Influence of Specific Bacteroidales Strains on Gut and Liver Health Related to Metabolic Dysfunction-Associated Fatty Liver Disease. Probiotics and antimicrobial proteins, 17(3), 1498-1512. Article 101314. https://doi.org/10.1007/s12602-024-10219-1
Behrens, T., Balasubramanian, J., Ivask, M., Nõmm, M., Kavak, A., Secher, J. B.-M., Kadarmideen, H. N. & Rabaglino, M. B. (2025). In vitro processes alter the embryonic disc epigenome and transcriptome in the pre-implantation elongated bovine embryo. Biology of Reproduction, Article ioaf095. Advance online publication. https://doi.org/10.1093/biolre/ioaf095
Morin, M., Yin, W., MacLean, H., Devlin, B., Reichenberg, A., Swan, S. H., Buxbaum, J. D., Schendel, D., Persson, M., Laursen, T. M., Kolevzon, A., Grove, J., Klei, L., Roeder, K. & Sandin, S. (2025). Maternal body mass index in early pregnancy and autism in offspring: a population-based cohort study in Sweden and Denmark. BMC Medicine, 23(1), Article 620. https://doi.org/10.1186/s12916-025-04487-z
Sarrette, B., Luu, T. B., Johansson, A., Fliegmann, J., Pouzet, C., Pichereaux, C., Remblière, C., Sauviac, L., Carles, N., Amblard, E., Guyot, V., Bonhomme, M., Cullimore, J., Gough, C., Jacquet, C. & Pauly, N. (2025). Medicago truncatula SOBIR1 controls pathogen immunity and specificity in the Rhizobium-legume symbiosis. Plant, Cell and Environment, 48(1), 32-50. https://doi.org/10.1111/pce.15071
Jiang, Y., Wang, D., Zeng, S., Zhang, Y., Jiang, L., Pourmirzaei, M., Manshour, N., Esmaili, F., Zhang, W., Møller, I. M. & Xu, D. (2025). MULoc-target: Targeting peptide classification and detection using a protein language model. Briefings in bioinformatics, 26(4), Article bbaf436. https://doi.org/10.1093/bib/bbaf436
da Fonseca Junior, A. M., Ispada, J., de Lima , C. B., Trabuco do Amaral, D., Juan Ross, P., Kadarmideen, H. & Pecora Milazzoto, M. (2025). Multiomics integration uncovers metabolic control of H3K27ac in bovine inner cell masses. Biology of Reproduction, 1-10.