Molecular and translational neuroscience - DANDRITE

The Danish Research Institute of Translational Neuroscience – DANDRITE

is the Danish node of the Nordic EMBL Partnership for Molecular Medicine, and performs basic and translational research in brain and the nervous system.

Groups at DANDRITE encompass ambitious research programs that include:

Molecular and cellular mechanisms of memory
Effort-based decision making
Neuronal development and stem cells
Motor control
Brain processing of vision
Neurological and neurodegenerative diseases
Psychiatric disorders
Neurotrophic receptors, sorting
Structural biology of membrane transporters and receptors

Section coordinator at MBG/Director and Core Group Leader at DANDRITE

DANDRITE (Danish Research Institute of Translational Neuroscience)

Poul Nissen

Professor

M pn@mbg.au.dk
H 3130, 2.02
P +4587155508
P +4528992295

Group leaders at MBG/Group leaders at DANDRITE

Duda Kvitsiani

Group Leader, Associate Professor

M kvitsi@dandrite.au.dk
H 1182, 310

Sadegh Nabavi

Group Leader, Associate Professor

M snabavi@dandrite.au.dk
H 1182, 205
P +4593508246

Anne von Philipsborn

Group Leader, Associate Professor

M avp@dandrite.au.dk
H 1182, 204, lab. 220
P +4523359252

Junior group leader at MBG/Team leader at DANDRITE

Hanne Poulsen

Associate professor

M hp@mbg.au.dk
H 3132, 101
P +4530254065
P +4530254065

Group leader at MBG/AU-affiliated researcher at DANDRITE

Thomas Boesen

Cryo-EM Facility Manager

M thb@mbg.au.dk
H 3130, 2.13
P +4587155435

Thomas Boesen's research

Thomas Boesen's CV, publications, activities, etc.

Junior group leader at MBG-DANDRITE/iNANO

Magnus Kjærgaard

Assistant Professor

M magnus@mbg.au.dk
H 3135, 2.10

Affiliated researcher at MBG/DANDRITE

Marco Capogna

Professor

M marco.capogna@biomed.au.dk
H 1234, 222
P +4587168407

Marco Capogna's CV, publications, activities etc.
Marco Capogna's research

Peer-reviewed publications

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Kerwin, P., Yuan, J. & von Philipsborn, A. C. (2020). Female copulation song is modulated by seminal fluid. Nature Communications, 11(1), 1430. [1430]. https://doi.org/10.1038/s41467-020-15260-6

Hjorth-Jensen, S. J., Oksanen, E., Nissen, P. & Sørensen, T. L. M. (2020). Prospects for membrane protein crystals in NMX. In P. C. E. Moody (Ed.), Neutron Crystallography in Structural Biology (pp. 47-68). Elsevier. Methods in Enzymology, Vol.. 634 https://doi.org/10.1016/bs.mie.2019.11.019

Gotfryd, K., Boesen, T., Mortensen, J. S., Khelashvili, G., Quick, M., Terry, D. S., Missel, J. W., LeVine, M. V., Gourdon, P., Blanchard, S. C., Javitch, J. A., Weinstein, H., Loland, C. J., Nissen, P. & Gether, U. (2020). X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release. Nature Communications, 11(1), [1005]. https://doi.org/10.1038/s41467-020-14735-w

Bonaventura, J., Eldridge, M. A. G., Hu, F., Gomez, J. L., Sanchez-Soto, M., Abramyan, A. M., Lam, S., Boehm, M. A., Ruiz, C., Farrell, M. R., Moreno, A., Galal Faress, I. M., Andersen, N., Lin, J. Y., Moaddel, R., Morris, P. J., Shi, L., Sibley, D. R., Mahler, S. V. ... Michaelides, M. (2019). High-potency ligands for DREADD imaging and activation in rodents and monkeys. Nature Communications, 10(1), [4627]. https://doi.org/10.1038/s41467-019-12236-z

Kidmose, R. T., Juhl, J., Nissen, P., Boesen, T., Karlsen, J. L. & Pedersen, B. P. (2019). Namdinator - Automatic molecular dynamics flexible fitting of structural models into cryo-EM and crystallography experimental maps. IUCrJ, 6(4), 526-531. https://doi.org/10.1107/S2052252519007619

Elfarrash, S., Jensen, N. M., Ferreira, N., Betzer, C., Thevathasan, J. V., Diekmann, R., Adel, M., Omar, N. M., Boraie, M. Z., Gad, S., Ries, J., Kirik, D., Nabavi, S. & Jensen, P. H. (2019). Organotypic slice culture model demonstrates inter-neuronal spreading of alpha-synuclein aggregates. Acta Neuropathologica Communications, 7(1), [213]. https://doi.org/10.1186/s40478-019-0865-5

Dyla, M., Basse Hansen, S., Nissen, P. & Kjaergaard, M. (2019). Structural dynamics of P-type ATPase ion pumps. Biochemical Society Transactions, 47(5), 1247-1257. https://doi.org/10.1042/BST20190124

Timcenko, M., Lyons, J. A., Januliene, D., Ulstrup, J. J., Dieudonné, T., Montigny, C., Ash, M. R., Karlsen, J. L., Boesen, T., Kühlbrandt, W., Lenoir, G., Moeller, A. & Nissen, P. (2019). Structure and autoregulation of a P4-ATPase lipid flippase. Nature, 571(7765), 366-370. https://doi.org/10.1038/s41586-019-1344-7

Sitsel, A., De Raeymaecker, J., Drachmann, N. D., Derua, R., Smaardijk, S., Andersen, J. L., Vandecaetsbeek, I., Chen, J., De Maeyer, M., Waelkens, E., Olesen, C., Vangheluwe, P. & Nissen, P. (2019). Structures of the heart specific SERCA2a Ca ²⁺ -ATPase. EMBO Journal, 38(5), [e100020]. https://doi.org/10.15252/embj.2018100020

Nissen, P. (2019). Thomas A. Steitz (1940-2018). Acta crystallographica Section D: Structural biology , 75, 354-356. https://doi.org/10.1107/S2059798319002390

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Lisbeth Heilesen

Revised 27.05.2020

Department of Molecular Biology and Genetics

Molecular and translational neuroscience - DANDRITE

The Danish Research Institute of Translational Neuroscience – DANDRITE

Section coordinator at MBG/Director and Core Group Leader at DANDRITE

Poul Nissen

Poul Nissen's research

Poul Nissen's CV, publications, activities, etc.

Group leaders at MBG/Group leaders at DANDRITE

Duda Kvitsiani

Duda Kvitsiani's research

Duda Kvitsiani's CV, publications, activities, etc.

Sadegh Nabavi

Sadegh Nabavi's research

Sadegh Nabavi's CV, publications, activities, etc.

Anne von Philipsborn

Anne von Philipsborn's research

Anne von Philipsborn's CV, publications, activities, etc.

Junior group leader at MBG/Team leader at DANDRITE

Hanne Poulsen

Hanne Poulsen's research

Hanne Poulsen's CV, publications, activities etc.

Group leader at MBG/AU-affiliated researcher at DANDRITE

Thomas Boesen

Thomas Boesen's research

Thomas Boesen's CV, publications, activities, etc.

Junior group leader at MBG-DANDRITE/iNANO

Magnus Kjærgaard

Magnus Kjærgaard's research

Magnus Kjærgaard's CV, publications, activities, etc.

Affiliated researcher at MBG/DANDRITE

Marco Capogna

Marco Capogna's CV, publications, activities etc.
Marco Capogna's research

Peer-reviewed publications