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Lars-Erik Holm

Research areas

My research interest is in improving the understanding of inheritance of genes with a different inheritance than the normal equal contributions from each of the parents with a focus on imprinted genes which show expression based on parent-of-origin of the transcript. Increasing the knowledge of imprinted genes and their inheritance is primarily addressed using next generation sequencing (NGS) and bioinformatics approaches.

I have an additional interest in looking at genetic variation both in specific genes and at the genome-wide level based on NGS data to understand differences between species or races within a species or the evolutionary development of these groups of individuals. This is with the primary goal of increasing the understanding of the relation between specific genetic variants and associated phenotypic traits.