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Neurobiology

The Section for Neurobiology is part of the Danish Research Institute of Translational Neuroscience – DANDRITE 

- the Danish node of the Nordic EMBL Partnership for Molecular Medicine, which performs basic and translational research in brain and the nervous system.  

Groups at DANDRITE encompass ambitious research programs that include:

  • Molecular and cellular mechanisms of memory
  • Effort-based decision making
  • Neuronal development and stem cells
  • Motor control
  • Brain processing of vision
  • Neurological and neurodegenerative diseases
  • Psychiatric disorders
  • Neurotrophic receptors, sorting
  • Structural biology of membrane transporters and receptors

Read more about the research at DANDRITE.

Below you see the list of researchers at DANDRITE affiliated with the Department of Molecular Biology and Genetics.

Group leaders

Professors

Associate Professors

Tenure Track Assistant Professor

Professor

Associate Professors

Tenure Track Assistant Professor

Peer-reviewed publications

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Bøttger, P., Pedersen, S. G., Gesslein, B., Illarionova, N., Isaksen, T. J., Heuck, A., Clausen, B. H., Füchtbauer, E.-M., Gramsbergen, J. B., Gunnarson, E., Aperia, A., Lauritzen, M., Lambertsen, K. L., Nissen, P. & Lykke-Hartmann, K. (2016). Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model. Scientific Reports, 6(22047), Article 22047. https://doi.org/10.1038/srep22047
Bonaventura, J., Eldridge, M. A. G., Hu, F., Gomez, J. L., Sanchez-Soto, M., Abramyan, A. M., Lam, S., Boehm, M. A., Ruiz, C., Farrell, M. R., Moreno, A., Galal Faress, I. M., Andersen, N., Lin, J. Y., Moaddel, R., Morris, P. J., Shi, L., Sibley, D. R., Mahler, S. V. ... Michaelides, M. (2019). High-potency ligands for DREADD imaging and activation in rodents and monkeys. Nature Communications, 10(1), Article 4627. https://doi.org/10.1038/s41467-019-12236-z
Boesecke, P., Bois, J. M., Crëpin, T., Hunte, C., Kahn, R., Kao, W.-C., Nauton, L., Winther, A.-M. L., Møller, J. V., Nissen, P., Nury, H., Olesen, C. E., Pebay-Peyroula, E., Vicat, J. & Stuhrmann, H. (2009). A first low-resolution difference Fourier map of phosphorus in a membrane protein from near-edge anomalous diffraction. Journal of Synchrotron Radiation, 16(5), 658-665.
Bianchini, E., Testoni, S., Gentile, A., Calì, T., Ottolini, D., Villa, A., Brini, M., Betto, R., Mascarello, F., Sandonà, D., Sacchetto, R. & Nissen, P. (2014). Inhibition of Ubiquitin Proteasome System Rescues the Defective Sarco(endo)plasmic Reticulum Ca2+-ATPase (SERCA1) Protein Causing Chianina Cattle Pseudomyotonia. Journal of Biological Chemistry, 289(48), 33073-33082. https://doi.org/10.1074/jbc.M114.576157
Bay, Y., Venskutonytė, R., Frantsen, S. M., Thorsen, T. S., Musgaard, M., Frydenvang, K., Francotte, P., Pirotte, B., Biggin, P. C., Kristensen, A. S., Boesen, T., Pickering, D. S., Gajhede, M. & Kastrup, J. S. (2024). Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure. FEBS journal, 291(7), 1506-1529. https://doi.org/10.1111/febs.17046