Department of Molecular Biology and Genetics

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Neurobiology

[Translate to English:] DANDRITE's logo

The Section for Neurobiology is part of the Danish Research Institute of Translational Neuroscience – DANDRITE 

- the Danish node of the Nordic EMBL Partnership for Molecular Medicine, which performs basic and translational research in brain and the nervous system.  

Groups at DANDRITE encompass ambitious research programs that include:

  • Molecular and cellular mechanisms of memory
  • Effort-based decision making
  • Neuronal development and stem cells
  • Motor control
  • Brain processing of vision
  • Neurological and neurodegenerative diseases
  • Psychiatric disorders
  • Neurotrophic receptors, sorting
  • Structural biology of membrane transporters and receptors

Read more about the research at DANDRITE.

Below you see the list of researchers at DANDRITE affiliated with the Department of Molecular Biology and Genetics.

Group leaders

Professors

Associate Professors

Tenure Track Assistant Professor

Professor

Associate Professors

Tenure Track Assistant Professor

Peer-reviewed publications

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Boesen, T., Nielsen, L. P. & Schramm, A. (2021). Pili for nanowires. Nature Microbiology, 6(11), 1347-1348. https://doi.org/10.1038/s41564-021-00990-0
Boesecke, P., Bois, J. M., Crëpin, T., Hunte, C., Kahn, R., Kao, W.-C., Nauton, L., Winther, A.-M. L., Møller, J. V., Nissen, P., Nury, H., Olesen, C. E., Pebay-Peyroula, E., Vicat, J. & Stuhrmann, H. (2009). A first low-resolution difference Fourier map of phosphorus in a membrane protein from near-edge anomalous diffraction. Journal of Synchrotron Radiation, 16(5), 658-665.
iNEXT Consortium (2018). iNEXT: a European facility network to stimulate translational structural biology. FEBS Letters, 592(12), 1909-1917. https://doi.org/10.1002/1873-3468.13062
Bocchio, M., Nabavi, S. & Capogna, M. (2017). Synaptic Plasticity, Engrams, and Network Oscillations in Amygdala Circuits for Storage and Retrieval of Emotional Memories. Neuron, 94(4), 731-743. https://doi.org/10.1016/j.neuron.2017.03.022
Bianchini, E., Testoni, S., Gentile, A., Calì, T., Ottolini, D., Villa, A., Brini, M., Betto, R., Mascarello, F., Sandonà, D., Sacchetto, R. & Nissen, P. (2014). Inhibition of Ubiquitin Proteasome System Rescues the Defective Sarco(endo)plasmic Reticulum Ca2+-ATPase (SERCA1) Protein Causing Chianina Cattle Pseudomyotonia. Journal of Biological Chemistry, 289(48), 33073-33082. https://doi.org/10.1074/jbc.M114.576157
Bay, Y., Venskutonytė, R., Frantsen, S. M., Thorsen, T. S., Musgaard, M., Frydenvang, K., Francotte, P., Pirotte, B., Biggin, P. C., Kristensen, A. S., Boesen, T., Pickering, D. S., Gajhede, M. & Kastrup, J. S. (2024). Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure. FEBS journal, 291(7), 1506-1529. https://doi.org/10.1111/febs.17046
Basse Hansen, S., Flygaard, R. K., Kjaergaard, M. & Nissen, P. (2025). Structure of the [Ca]E2P intermediate of Ca2+-ATPase 1 from Listeria monocytogenes. EMBO Reports, 26(7), 1709-1723. Article eadd9742. https://doi.org/10.1038/s44319-025-00392-x
Ban, N., Nissen, P., Hansen, J., Moore, P. B. & Steitz, T. A. (2000). The complete atomic structure of the large ribosomal subunit at 2.4 A resolution. Science, 289, 905-920.
Azouaoui, H., Montigny, C., Ash, M.-R., Fijalkowski, F., Jacquot, A., Grønberg, C., López-Marqués, R. L., Palmgren, M. G., Garrigos, M., le Maire, M., Decottignies, P., Gourdon, P., Nissen, P., Champeil, P. & Lenoir, G. (2014). A high-yield co-expression system for the purification of an intact drs2p-cdc50p lipid flippase complex, critically dependent on and stabilized by phosphatidylinositol-4-phosphate. PLoS One, 9(11), Article e112176. https://doi.org/10.1371/journal.pone.0112176
Azouaoui, H., Montigny, C., Dieudonné, T., Champeil, P., Jacquot, A., Vázquez-Ibar, J. L., le Maréchal, P., Ulstrup, J., Ash, M.-R., Lyons, J. A., Nissen, P. & Lenoir, G. (2017). A High and Phosphatidylinositol-4-phosphate (PI4P)-dependent ATPase Activity for the Drs2p/Cdc50p Flippase after Removal of its N- and C-terminal Extensions. Journal of Biological Chemistry, 292(19), 7954-7970. https://doi.org/10.1074/jbc.M116.751487
Azizan, E. A. B., Poulsen, H., Tuluc, P., Zhou, J., Clausen, M., Lieb, A., Maniero, C., Garg, S., Bochukova, E. G., Zhao, W., Shaikh, L. H., Brighton, C. A., Teo, A. E. D., Davenport, A. P., Dekkers, T., Tops, B., Küsters, B., Ceral, J., Yeo, G. S. H. ... Brown, M. J. (2013). Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension. Nature Genetics, 45(9), 1055-1060. https://doi.org/10.1038/ng.2716
Autzen, H. E., Siuda, I., Sonntag, Y., Nissen, P., Møller, J. V. & Thøgersen, L. (2015). Regulation of the Ca(2+)-ATPase by cholesterol: A specific or non-specific effect? Molecular Membrane Biology, 32(3), 75-87. https://doi.org/10.3109/09687688.2015.1073382

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Revised 13.11.2025
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Helene Eriksen