Department of Molecular Biology and Genetics

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 Department of Molecular Biology and Genetics Research Research areas Neurobiology

Neurobiology

[Translate to English:] DANDRITE's logo

The Section for Neurobiology is part of the Danish Research Institute of Translational Neuroscience – DANDRITE 

- the Danish node of the Nordic EMBL Partnership for Molecular Medicine, which performs basic and translational research in brain and the nervous system.  

Groups at DANDRITE encompass ambitious research programs that include:

  • Molecular and cellular mechanisms of memory
  • Effort-based decision making
  • Neuronal development and stem cells
  • Motor control
  • Brain processing of vision
  • Neurological and neurodegenerative diseases
  • Psychiatric disorders
  • Neurotrophic receptors, sorting
  • Structural biology of membrane transporters and receptors

Read more about the research at DANDRITE.

Below you see the list of researchers at DANDRITE affiliated with the Department of Molecular Biology and Genetics.

Group leaders

Professors

Associate Professors

Tenure Track Assistant Professor

Professor

Associate Professors

Tenure Track Assistant Professor

Peer-reviewed publications

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Verzelli, P., Nold, A., Sun, C., Heilemann, M., Schuman, E. M. & Tchumatchenko, T. (2022). Unbiased choice of global clustering parameters for single-molecule localization microscopy. Scientific Reports, 12(1), 22561. Article 22561. https://doi.org/10.1038/s41598-022-27074-1
Neumann, C., Focht, D., Trampari, S., Lyons, J. A. & Nissen, P. (2022). Variations on a theme: Crystal forms of the amino-acid transporter MhsT. Acta Crystallographica Section F: Structural Biology Communications, 78(Part 8), 297-305. https://doi.org/10.1107/S2053230X22007154
Focht, D., Neumann, C., Lyons, J., Eguskiza Bilbao, A., Blunck, R., Malinauskaite, L., Schwarz, I. O., Javitch, J. A., Quick, M. & Nissen, P. (2021). A non-helical region in transmembrane helix 6 of hydrophobic amino acid transporter MhsT mediates substrate recognition. EMBO Journal, 40(1), Article e105164. https://doi.org/10.15252/embj.2020105164
Krintel, C., Dorosz, J., Larsen, A. H., Thorsen, T. S., Venskutonytė, R., Mirza, O., Gajhede, M., Boesen, T. & Kastrup, J. S. (2021). Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2. FEBS journal, 288(3), 995-1007. https://doi.org/10.1111/febs.15455
Mermet-Joret, N., Capogna, M. & Nabavi, S. (2021). Fear Memory Relapse: The Importance of Input Associativity. Trends in Neurosciences, 44(5), 337-339. https://doi.org/10.1016/j.tins.2021.02.006
Christensen, S. B., Simonsen, H. T., Engedal, N., Nissen, P., Møller, J. V., Denmeade, S. R. & Isaacs, J. T. (2021). From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development. In A. D. Kinghorn, H. Falk, S. Gibbons, Y. Asakawa, J. K. Liu & V. M. Dirsch (Eds.), Progress in the Chemistry of Organic Natural Products (Vol. 115, pp. 59-114). Springer. https://doi.org/10.1007/978-3-030-64853-4_2
Roeters, S. J., Golbek, T. W., Bregnhøj, M., Drace, T., Alamdari, S., Roseboom, W., Kramer, G., Šantl-Temkiv, T., Finster, K., Pfaendtner, J., Woutersen, S., Boesen, T. & Weidner, T. (2021). Ice-nucleating proteins are activated by low temperatures to control the structure of interfacial water. Nature Communications, 12(1), Article 1183. https://doi.org/10.1038/s41467-021-21349-3
Trampari, S., Neumann, C. M. T., Hjorth-Jensen, S. J., Shahsavar, A., Quistgaard, E. M. H. & Nissen, P. (2021). Insights into the mechanism of high lipid–detergent crystallization of membrane proteins. Journal of Applied Crystallography, 54(Part 6), 1775-1783. https://doi.org/10.1107/S1600576721010669
Dach, I. & Nissen, P. (2021). Membrane transport | Structure of P-Type adenosine triphosphatases. In Encyclopedia of Biological Chemistry: Third Edition (Vol. 2, pp. 1014-1020). Elsevier. https://doi.org/10.1016/B978-0-12-819460-7.00626-5
Quistgaard, E. M. H., Nissen, J. D., Hansen, S. & Nissen, P. (2021). Mind the gap: molecular architecture of the axon initial segment – from fold prediction to a mechanistic model of function? Journal of Molecular Biology, 433(20), Article 167176. https://doi.org/10.1016/j.jmb.2021.167176
Boesen, T., Nielsen, L. P. & Schramm, A. (2021). Pili for nanowires. Nature Microbiology, 6(11), 1347-1348. https://doi.org/10.1038/s41564-021-00990-0
Elfarrash, S., Jensen, N. M., Ferreira, N., Schmidt, S. I., Gregersen, E., Vestergaard, M. V., Nabavi, S., Meyer, M. & Jensen, P. H. (2021). Polo-like kinase 2 inhibition reduces serine-129 phosphorylation of physiological nuclear alpha-synuclein but not of the aggregated alpha-synuclein. PLoS One, 16(10), Article e0252635. https://doi.org/10.1371/journal.pone.0252635

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Revised 13.11.2025
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Helene Eriksen