Institut for Molekylærbiologi og Genetik

Aarhus Universitets segl

Lene Pedersen

Area of research

  • cellular inorganic phosphate homeostasis
  • type III inorganic phosphate transporters and their physiologic and pathologic roles including in neurobiology and vascular calcification
  • inorganic phosphate in normal and pathologic mineralization
  • vascular calcification
  • familial idiopathic basal ganglia calcification (FIBGC) (Fahr’s disease)
  • causes of and effects of hyperphosphatemia
  • cardiovascular diseases; cancer; cell metabolism and aging
  • stem cells
  • osteblastic differentiation
  • retroviral infection
  • retroviral pathology
  • retroviral receptor functions
  • retroviral vector technology

Peer-reviewed publications

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Uckert, W., Becker, C., Gladow, M., Klein, D., Kammertoens, T., Pedersen, L. & Blankenstein, T. (2000). Efficient gene transfer into primary human CD8+ T Lymphocytes by MuLV-10A1 retrovirus pseudotype. Human Gene Therapy, 11, 1005-1014.
Uckert, W., Willimsky, G., Pedersen, F. S., Blankenstein, T. & Pedersen, L. (1998). RNA levels of human retrovirus receptors Pit1 and Pit2 do not correlate with infectibility by three retroviral vector pseudotypes. Human Gene Therapy, 9(17), 2619-2627. https://doi.org/10.1089/hum.1998.9.17-2619
Strauss, P. G., Schmidt, J., Pedersen, L. & Erfle, V. (1988). Amplification of endogenous proviral MuLV sequences in radiation-induced osteosarcomas. International Journal of Cancer, 41(4), 616-621. https://doi.org/10.1002/ijc.2910410423
Sørensen, S. S., Lundby, J. M. B. & Pedersen, L. (2023). Lack of inorganic phosphate transporter associated with development of anxiety behavior in female mice. Abstract fra 20th Annual Vienna BioCenter PhD Program Symposium, Vienna, Østrig.
Søndergaard, C. S., Haldrup, C. & Pedersen, L. (2004). Efficiency of preloading of retroviral vectors without fibronectin peptide CH-296 is packing cell clone dependent. Molecular Therapy, 9, 279-279.

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Revideret 17.04.2026
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Lisbeth Heilesen