Publikationer

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Tidsskriftsforsider lavet af forskere fra MBG

Peer-review'ede publikationer ved MBG - 2025

Kofod Petersen, A., Forgie, A., Villesen, P. & Staun Larsen, L. (2025). 3D dental similarity quantification in forensic odontology identification. Forensic Science International, 370, Artikel 112462. https://doi.org/10.1016/j.forsciint.2025.112462

Hong, Z., Tesic, N. & Bofill-De Ros, X. (2025). Analysis of Processing, Post-Maturation, and By-Products of shRNA in Gene and Cell Therapy Applications. Methods and Protocols, 8(2), Artikel 38. https://doi.org/10.3390/mps8020038

Kriebisch, C. M. E., Bantysh, O., Baranda Pellejero, L., Belluati, A., Bertosin, E., Dai, K., de Roy, M., Fu, H., Galvanetto, N., Gibbs, J. M., Gomez, S. S., Granatelli, G., Griffo, A., Guix, M., Gurdap, C. O., Harth-Kitzerow, J., Haugerud, I. S., Häfner, G., Jaiswal, P. ... Boekhoven, J. (2025). A roadmap toward the synthesis of life. Chem, 11(3), Artikel 102399. https://doi.org/10.1016/j.chempr.2024.102399

Theologidis, V., Ferreira, S. A., Jensen, N. M., Gomes Moreira, D., Ahlgreen, O. A., Hansen, M. W., Rosenberg, E. D., Richner, M., Faress, I., Gram, H., Jensen, P. H., Borghammer, P., Nyengaard, J. R., Romero-Ramos, M., Vægter, C. B., van de Berg, W. D. J., Van Den Berge, N. & Jan, A. (2025). Bradykinesia and postural instability in a model of prodromal synucleinopathy with α-synuclein aggregation initiated in the gigantocellular nuclei. Acta Neuropathologica Communications, 13(1), 32. Artikel 32. https://doi.org/10.1186/s40478-025-01948-7

Bendtsen, M. K., Nowak, J. S., Paiva, P., López Hernández, M., Ferreira, P., Pedersen, J. S., Bekker, N. S., Viezzi, E., Bisiak, F., Brodersen, D. E., Pedersen, L. H., Zervas, A., Fernandes, P. A., Ramos, M. J., Stougaard, P., Thøgersen, M. S. & Otzen, D. E. (2025). Cold-Active Starch-Degrading Enzymes from a Cold and Alkaline Greenland Environment: Role of Ca²⁺ Ions and Conformational Dynamics in Psychrophilicity. Biomolecules, 15(3), Artikel 415. https://doi.org/10.3390/biom15030415

Digel, L., Justesen, M. L., Madsen, N. S., Fransaert, N., Wouters, K., Bonné, R., Plum-Jensen, L. E., Marshall, I. P. G., Jensen, P. B., Nicolas-Asselineau, L., Drace, T., Bøggild, A., Hansen, J. L., Schramm, A., Bøjesen, E. D., Nielsen, L. P., Manca, J. V. & Boesen, T. (2025). Comparison of cable bacteria genera reveals details of their conduction machinery. EMBO Reports, 26(7), 1749-1767. Artikel 13699. https://doi.org/10.1038/s44319-025-00387-8

Prip, F., Lamy, P., Lindskrog, S. V., Strandgaard, T., Nordentoft, I., Birkenkamp-Demtröder, K., Birkbak, N. J., Kristjánsdóttir, N., Kjær, A., Andreasen, T. G., Ahrenfeldt, J., Pedersen, J. S., Rasmussen, A. M., Hermann, G. G., Mogensen, K., Petersen, A. C., Hartmann, A., Grimm, M. O., Horstmann, M. ... UROMOL Consortium (2025). Comprehensive genomic characterization of early-stage bladder cancer. Nature Genetics, 57(1), 115-125. Artikel 2301. https://doi.org/10.1038/s41588-024-02030-z

Nguyen, M. T. A., Andersen, E. S. & Pothoulakis, G. (2025). Construction of Small Genes with Repetitive Elements Using Oligo Extension and Golden Gate Assembly. I D. Schindler (red.), Golden Gate Cloning (s. 219-227). Humana Press. https://doi.org/10.1007/978-1-0716-4220-7_12

Sall, K. K., Foldager, L., Delf, C., Christensen, S. J., Agerley, M. N., Havn, K. T. & Pedersen, C. (2025). Control of neonatal diarrhea in piglets with reduced antibiotic use by application of a complementary feed - a randomized controlled farm trial. Veterinary Sciences, 12(1), Artikel 42. https://doi.org/10.3390/vetsci12010042

Rashidi, A., Füchtbauer, E. M., Vahabzadeh, Z., Soleimani, F., Rahimi, K., Nikkhoo, B., Fakhari, S., Erfan, M. B. K., Azarnezhad, A., Pooladi, A., Soheili, F. & Fathi, F. (2025). CRISPR/Cas9-mediated knockout of DYRK1B in triple-negative breast cancer cells: implications for cell proliferation, apoptosis, and therapeutic sensitivity. Biochemical Engineering Journal, 213, Artikel 109553. https://doi.org/10.1016/j.bej.2024.109553

Kjær, M. B., Jørgensen, A. G., Fjelstrup, S., Dupont, D. M., Bus, C., Eriksen, P. L., Thomsen, K. L., Risikesan, J., Nielsen, S., Wernberg, C. W., Lauridsen, M. M., Bugianesi, E., Rosso, C., Grønbæk, H. & Kjems, J. (2025). Diagnosis and Staging of Metabolic Dysfunction-Associated Steatotic Liver Disease Using Biomarker-Directed Aptamer Panels. Biomolecules, 15(2), Artikel 255. https://doi.org/10.3390/biom15020255

Nybo, T., Gamon, L. F., Fuentes-Lemus, E., Otzen, D. E., Davies, M. J. & Hägglund, P. (2025). Dimethyl labeling of N-terminal amines allows unambiguous identification of protein crosslinks. Free Radical Biology & Medicine, 227, 629-637. https://doi.org/10.1016/j.freeradbiomed.2024.12.002

Gadegaard, I. S. E., Madsen, C. M., Johansen, P. M. & Rasmussen, J. T. (2025). Distribution, activity, and storage of xanthine oxidase in bovine milk fractions. International Dairy Journal, 160, Artikel 106091. https://doi.org/10.1016/j.idairyj.2024.106091

Bøtkjær, J. A., Poulsen, L. L. C., Noer, P. R., Grøndahl, M. L., Englund, A. L. M., Franks, S., Hardy, K., Oxvig, C. & Andersen, C. Y. (2025). Dynamics of IGF Signaling During the Ovulatory Peak in Women Undergoing Ovarian Stimulation. The Journal of clinical endocrinology and metabolism, 110(1), e160-e167. https://doi.org/10.1210/clinem/dgae132

Rasmussen, C. L. M., Frederiksen, S. F., Heegaard, C. W., Thomsen, M. S., Hede, E., Laczek, B., Körbelin, J., Wüstner, D., Thomsen, L. B., Schwaninger, M., Jensen, O. N., Moos, T. & Burkhart, A. (2025). Endothelial and neuronal engagement by AAV-BR1 gene therapy alleviates neurological symptoms and lipid deposition in a mouse model of Niemann-Pick type C2. Fluids and Barriers of the CNS, 22(1), Artikel 13. https://doi.org/10.1186/s12987-025-00621-4

Lassen, J. K. & Villesen, P. (2025). End-To-End Deep Learning Explains Antimicrobial Resistance in Peak-Picking-Free MALDI-MS Data. Analytical Chemistry, 97(5), 2795-2800. https://doi.org/10.1021/acs.analchem.4c05113

Charmouh, A. P., Porsborg, P. S., Hansen, L. T., Besenbacher, S., Boeg Winge, S., Almstrup, K., Hobolth, A., Bataillon, T. & Schierup, M. H. (2025). Estimating Gene Conversion Tract Length and Rate From PacBio HiFi Data. Molecular Biology and Evolution, 42(2), Artikel msaf019. https://doi.org/10.1093/molbev/msaf019

Radak, Z. & Rattan, S. I. S. (2025). Exercise, hormesis and ageing: a new section in Biogerontology. Biogerontology, 26(1), 26. Artikel 26. https://doi.org/10.1007/s10522-024-10170-2

Yuan, H., Mitchell, C. W., Ferenbach, A. T., Bonati, M. T., Feresin, A., Benke, P. J., Tan, Q. K. G. & van Aalten, D. M. F. (2025). Exploiting O-GlcNAc dyshomeostasis to screen O-GlcNAc transferase intellectual disability variants. Stem Cell Reports, 20(1), 102380. Artikel 102380. https://doi.org/10.1016/j.stemcr.2024.11.010

Khachadourian, V., Arildskov, E. S., Grove, J., O'Reilly, P. F., Buxbaum, J. D., Reichenberg, A., Sandin, S., Croen, L. A., Schendel, D., Hansen, S. N. & Janecka, M. (2025). Familial confounding in the associations between maternal health and autism. Nature Medicine, 31(3), 996-1007. https://doi.org/10.1038/s41591-024-03479-5

Mundy, J., Hall, A. S. M., Agerbo, E., Albiñana, C., Steinbach, J., Vilhjálmsson, B. J., Østergaard, S. D. & Musliner, K. L. (2025). Genetic Confounding of the Association Between Age at First Hormonal Contraception and Depression. Acta Psychiatrica Scandinavica, 151(4), 529-536. https://doi.org/10.1111/acps.13774

Cabrejas-Olalla, A., Jørgensen, F. G., Cheng, J. Y., Kjærgaard, P. C., Schierup, M. H., Mailund, T. & Athanasiadis, G. (2025). Genetic predictions of eye and hair colour in the Danish population. Forensic Science International: Genetics, 78, Artikel 103267. https://doi.org/10.1016/j.fsigen.2025.103267

Wakabayashi, T., Andersen, S. U., Tanaka, S., Sato, S., Kawaguchi, M., Kato, K. & Setoguchi, H. (2025). Genome-wide association study identifies candidate genes contributing to flowering time variation in Lotus japonicus in Japan. Plant Biotechnology, 42(1), 17-29. https://doi.org/10.5511/plantbiotechnology.24.1023a

PGC TS Working Group & 23andMe Research Team (2025). Genome-Wide Association Study Meta-Analysis of 9619 Cases With Tic Disorders. Biological Psychiatry, 97(7), 743-752. https://doi.org/10.1016/j.biopsych.2024.07.025

23andMe Research Team (2025). Genomics yields biological and phenotypic insights into bipolar disorder. Nature, 639, 968-975. Artikel 2417. https://doi.org/10.1038/s41586-024-08468-9

Qin, Q., Wei, P., Usman, S., Ahamefule, C. S., Jin, C., Wang, B., Yan, K., van Aalten, D. M. F. & Fang, W. (2025). Gfa1 (glutamine fructose-6-phosphate aminotransferase) is essential for Aspergillus fumigatus growth and virulence. BMC Biology, 23(1), Artikel 80. https://doi.org/10.1186/s12915-025-02184-0

Li, Z., Xue, Y., Duan, Y., Yuan, W., Chen, C., Shi, S., Su, X. C., Kisiswa, L., Fan, J. S. & Lin, Z. (2025). Heterotypic interactions among members of the death domain superfamily with implications for p75^NTR-mediated co-signaling. International Journal of Biological Macromolecules, 304(Part 1), Artikel 140791. https://doi.org/10.1016/j.ijbiomac.2025.140791

Andersen, H. H., Andersen, M. K., Bossow, K. A., Vestergaard, A. L., Bor, P. & Larsen, A. (2025). High-dose vitamin D supplementation in pregnancy ameliorates obesity-induced increase in maternal IL-1β level without affecting obesity-induced increase in IL-6 and MCP. The Journal of Steroid Biochemistry and Molecular Biology, 250, Artikel 106742. https://doi.org/10.1016/j.jsbmb.2025.106742

Li, Q., Marietou, A., Andersen, F. F., Hosek, J., Scavenius, C., Zhang, J. & Schwab, C. (2025). In vitro investigations on the impact of fermented dairy constituents on fecal microbiota composition and fermentation activity. Microbiology Spectrum, 13(3), e0219324. https://doi.org/10.1128/spectrum.02193-24

Dardani, C., Robinson, J. W., Jones, H. J., Rai, D., Stergiakouli, E., Grove, J., Gardner, R., McIntosh, A. M., Havdahl, A., Hemani, G., Davey Smith, G., Richardson, T. G., Gaunt, T. R. & Khandaker, G. M. (2025). Immunological drivers and potential novel drug targets for major psychiatric, neurodevelopmental, and neurodegenerative conditions. Molecular Psychiatry, Artikel e1004092. Advance online publication. https://doi.org/10.1038/s41380-025-03032-x

Bruhn, D., Griffin, K. L. & Møller, I. M. (2025). Importance of Timing of Dark Acclimation for Estimating Light Inhibition of Leaf Respiratory CO₂ Efflux. Plant, Cell & Environment, 48(5), 3151-3158. https://doi.org/10.1111/pce.15335

Wang, J., Kidmose, R. T., Boegholm, N., Zacharia, N. K., Thomsen, M. B., Christensen, A., Malik, T., Lechtreck, K. & Lorentzen, E. (2025). Integrative in silico and biochemical analyses demonstrate direct Arl3-mediated ODA16 release from the intraflagellar transport machinery. Journal of Biological Chemistry, 301(3), Artikel 108237. https://doi.org/10.1016/j.jbc.2025.108237

Otzen, D. E., Peña-Díaz, S., Widmann, J., Daugberg, A. O. H., Zhang, Z., Jiang, Y., Mittal, C., Dueholm, M. K. D., Louros, N., Wang, H. & Javed, I. (2025). Interactions between pathological and functional amyloid: A match made in Heaven or Hell? Molecular Aspects of Medicine, 103, 101351. Artikel 101351. Advance online publication. https://doi.org/10.1016/j.mam.2025.101351

Olsen, W. P., Larsen, A.-K. K., Christensen, J. L., Malle, M. G. & Otzen, D. E. (2025). Investigating strategies for creating cross-linked amyloid fibril networks through branching of amyloid growth. Colloids and surfaces. B, Biointerfaces, 251, 114617. Artikel 114617. Advance online publication. https://doi.org/10.1016/j.colsurfb.2025.114617

López Hernández, M., Otzen, D. E. & Pedersen, J. S. (2025). Investigating the interactions between an industrial lipase and anionic (bio)surfactants. Journal of Colloid and Interface Science, 679(B), 294-306. https://doi.org/10.1016/j.jcis.2024.10.060

Buhl, E. H., Christensen, B., Pedersen, F. H. & S⊘rensen, E. S. (2025). Milk osteopontin has high iron-binding capacity and facilitates iron absorption in intestinal cells. Journal of Dairy Science, 108(1), 90-100. https://doi.org/10.3168/jds.2024-25305

Christensen, B., Krüger, T. F., Hjorth, T. P., Buhl, E. H. & Sørensen, E. S. (2025). Milk osteopontin mediates zinc uptake in intestinal cells in the presence of phytic acid. International Dairy Journal, 161, Artikel 106113. https://doi.org/10.1016/j.idairyj.2024.106113

Boonkaew, S., Teodori, L., Vendelbo, M. H., Kjems, J. & Ferapontova, E. E. (2025). Nanobodies' duo facilitates ultrasensitive serum HER-2/neu immunoassays via enhanced avidity interactions. Analytica Chimica Acta, 1335, Artikel 343472. https://doi.org/10.1016/j.aca.2024.343472

Subrahmaniam, H. J., Pico, X., Bataillon, T., Salomonsen, C. L., Glasius, M. & Ehlers, B. (2025). Natural variation in root exudate composition in the genetically structured Arabidopsis thaliana in the Iberian Peninsula. New Phytologist, 245(4), 1437-1449. https://doi.org/10.1111/nph.20314

Bryzek, D., Gasiorek, A., Kowalczyk, D., Santocki, M., Ciaston, I., Dobosz, E., Kolaczkowska, E., Kjøge, K., Kantyka, T., Lech, M., Potempa, B., Enghild, J. J., Potempa, J. & Koziel, J. (2025). Non-classical neutrophil extracellular traps induced by PAR2-signaling proteases. Cell Death & Disease, 16(1), 109. Artikel 109. https://doi.org/10.1038/s41419-025-07428-z

Broksø, A. D., Bendixen, L., Fammé, S., Mikkelsen, K., Jensen, T. I. & Bak, R. O. (2025). Orthogonal transcriptional modulation and gene editing using multiple CRISPR/Cas systems. Molecular Therapy, 33(1), 71-89. https://doi.org/10.1016/j.ymthe.2024.11.024

Mirab, F., Pirhaghi, M., Otzen, D. E. & Saboury, A. A. (2025). Parkinson's disease and gut microbiota metabolites: The dual impact of vitamins and functional amyloids. B B A - Molecular Basis of Disease, 167862. Advance online publication. https://doi.org/10.1016/j.bbadis.2025.167862

Schlosser, A., Pilecki, B., Allen, C., Benest, A. V., Lynch, A. P., Hua, J., Ved, N., Blackley, Z., Andersen, T. L., Hennig, D., Graversen, J. H., Möller, S., Skallerup, S., Ormhøj, M., Lange, C., Agostini, H. T., Grauslund, J., Heegaard, S., Dacheva, I. ... Sorensen, G. L. (2025). Pharmacological blocking of microfibrillar-associated protein 4 reduces retinal neoangiogenesis and vascular leakage. Molecular Therapy, 33(3), 1048-1072. https://doi.org/10.1016/j.ymthe.2025.01.038

APEX consortium & Mortensen, P. B. (2025). Polygenic scores for autism are associated with reduced neurite density in adults and children from the general population. Molecular Psychiatry, Artikel 2301. Advance online publication. https://doi.org/10.1038/s41380-025-02927-z

Martín-Rivada, Á., Martos-Moreno, G., Guerra-Cantera, S., Campillo-Calatayud, A., Oxvig, C., Frystyk, J., Chowen, J. A., Barrios, V. & Argente, J. (2025). Prepubertal Children With Obesity Have High Free IGF-1 Levels and Accelerated Growth Despite Reduced Pappalysin Levels. Journal of Clinical Endocrinology and Metabolism, 110(3), e622-e629. https://doi.org/10.1210/clinem/dgae288

Nowak, J. S., Kruuse, N., Rasmussen, H. Ø., Tian, P., Astono, J., Schultz-Nielsen, S., Thøgersen, M. S., Stougaard, P., Pedersen, J. S. & Otzen, D. E. (2025). Quaternary stabilization of a GH2 β-galactosidase from the psychrophile A. ikkensis, a flexible and unstable dimeric enzyme. Protein Science, 34(5). https://doi.org/10.1002/pro.70141

Riedelbauch, S., Masser, S., Fasching, S., Lin, S. Y., Salgania, H. K., Aarup, M., Ebert, A., Jeske, M., Levine, M. T., Stelzl, U. & Andersen, P. (2025). Recurrent innovation of protein-protein interactions in the Drosophila piRNA pathway. EMBO Journal, Artikel 98. Advance online publication. https://doi.org/10.1038/s44318-025-00439-8

Golan, N., Parizat, A., Tabachnikov, O., Barnea, E., Olsen, W. P., Otzen, D. E. & Landau, M. (2025). Resilience and Charge-Dependent Fibrillation of functional amyloid: Interactions of Pseudomonas Biofilm-Associated FapB and FapC Amyloids. The Journal of Biological Chemistry, 301(2), Artikel 108096. https://doi.org/10.1016/j.jbc.2024.108096

Nowak, J. S., Olesen, S., Tian, P., Bærentsen, R. L., Brodersen, D. E. & Otzen, D. E. (2025). Role of electrostatics in cold adaptation: A comparative study of eury- and stenopsychrophilic triose phosphate isomerase. B B A - Proteins and Proteomics, 1873(4), Artikel 141072. https://doi.org/10.1016/j.bbapap.2025.141072

Hollingshead, S., McVicker, G., Nielsen, M. R., Zhang, Y., Pilla, G., Jones, R. A., Thomas, J. C., Johansen, S. E. H., Exley, R. M., Brodersen, D. E. & Tang, C. M. (2025). Shared mechanisms of enhanced plasmid maintenance and antibiotic tolerance mediated by the VapBC toxin:antitoxin system. mBio, 16(2), e0261624. https://doi.org/10.1128/mbio.02616-24

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Radak, Z. & Rattan, S. I. S. (2025). Exercise, hormesis and ageing: a new section in Biogerontology. Biogerontology, 26(1), 26. Artikel 26. https://doi.org/10.1007/s10522-024-10170-2

23andMe Research Team (2025). Genomics yields biological and phenotypic insights into bipolar disorder. Nature, 639, 968-975. Artikel 2417. https://doi.org/10.1038/s41586-024-08468-9

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Revideret 02.12.2024

Lisbeth Heilesen