Pothoulakis, G., Nguyen, M. T. A. & Andersen, E. S. (2022). Utilizing RNA origami scaffolds in Saccharomyces cerevisiae for dCas9-mediated transcriptional control. Nucleic Acids Research, 50(12), 7176-7187. https://doi.org/10.1093/nar/gkac470

Tapia-Galisteo, A., Sánchez Rodríguez, Í., Aguilar-Sopeña, O., Harwood, S. L., Narbona, J., Ferreras Gutierrez, M., Navarro, R., Martín-García, L., Corbacho, C., Compte, M., Lacadena, J., Blanco, F. J., Chames, P., Roda-Navarro, P., Álvarez-Vallina, L. & Sanz, L. (2022). Trispecific T-cell engagers for dual tumor-targeting of colorectal cancer. OncoImmunology, 11(1), [2034355]. https://doi.org/10.1080/2162402X.2022.2034355

Hansen, E. K. B., Fredsøe, J. H., Okholm, T. L. H., Ulhøi, B. P., Klingenberg, S., Jensen, J. B., Kjems, J., Bouchelouche, K., Borre, M., Damgaard, C. K., Pedersen, J. S., Kristensen, L. S. & Sørensen, K. D. (2022). The transcriptional landscape and biomarker potential of circular RNAs in prostate cancer. Genome Medicine, 14(1), [8]. https://doi.org/10.1186/s13073-021-01009-3

Møhlenberg, M., O’Brien, T. R. & Hartmann, R. (2022). The role of IFNL4 in liver inflammation and progression of fibrosis. Genes and Immunity, 23(3-4), 111-117. https://doi.org/10.1038/s41435-022-00173-9

Dyla, M., González Foutel, N. S., Otzen, D. E. & Kjaergaard, M. (2022). The optimal docking strength for reversibly tethered kinases. Proceedings of the National Academy of Sciences of the United States of America, 119(25), [e2203098119]. https://doi.org/10.1073/pnas.2203098119

Salimi, M., Tabasi, F., Nazari, M., Ghazvineh, S. & Raoufy, M. R. (2022). The olfactory bulb coordinates the ventral hippocampus–medial prefrontal cortex circuit during spatial working memory performance. Journal of Physiological Sciences, 72(1), [9]. https://doi.org/10.1186/s12576-022-00833-5

Mogensen, E. H., Poulsen, E. T., Thøgersen, I. B., Yamamoto, K., Brüel, A. & Enghild, J. J. (2022). The low-density lipoprotein receptor-related protein 1 (LRP1) interactome in the human cornea. Experimental Eye Research, 219, [109081]. https://doi.org/10.1016/j.exer.2022.109081

Kristensen, L. S., Jakobsen, T., Hager, H. & Kjems, J. (2022). The emerging roles of circRNAs in cancer and oncology. Nature Reviews. Clinical Oncology, 19(3), 188-206. https://doi.org/10.1038/s41571-021-00585-y

Gu, T., Just, J., Stenz, K. T., Yan, Y., Sieljacks, P., Wang, J., Groennebaek, T. S., Jakobsgaard, J. E., Rindom, E., Herskind, J., Gravholt, A., Lassen, T. R., Jørgensen, M., Bæk, R., Gutiérrez-Jiménez, E., Iversen, N. K., Rasmussen, P. M., Nyengaard, J. R., Jørgensen, M. M. ... Drasbek, K. R. (2022). The Role of Plasma Extracellular Vesicles in Remote Ischemic Conditioning and Exercise-Induced Ischemic Tolerance. International Journal of Molecular Sciences , 23(6), [3334]. https://doi.org/10.3390/ijms23063334

Fruergaard, M. U., Dach, I., Andersen, J. L., Ozol, M., Shasavar, A., Quistgaard, E. M. H., Poulsen, H., Fedosova, N. & Nissen, P. (2022). The Na,K-ATPase in complex with beryllium fluoride mimics an ATPase phosphorylated state. Journal of Biological Chemistry. https://doi.org/10.1016/j.jbc.2022.102317

Farzadfard, A., Pedersen, J. N., Meisl, G., Somavarapu, A. K., Alam, P., Goksøyr, L., Nielsen, M. A., Sander, A. F., Knowles, T. P. J., Pedersen, J. S. & Otzen, D. E. (2022). The C-terminal tail of α-synuclein protects against aggregate replication but is critical for oligomerization. Communications Biology, 5(1), [123]. https://doi.org/10.1038/s42003-022-03059-8

Jakobsen, A. K., Yuusufi, S., Madsen, L. B., Meldgaard, P., Knudsen, B. R. & Stougaard, M. (2022). TDP1 and TOP1 as targets in anticancer treatment of NSCLC: Activity and protein level in normal and tumor tissue from 150 NSCLC patients correlated to clinical data. Lung Cancer, 164, 23-32. https://doi.org/10.1016/j.lungcan.2021.12.010

Nguyen, M. T. A., Pothoulakis, G. & Andersen, E. S. (2022). Synthetic Translational Regulation by Protein-Binding RNA Origami Scaffolds. A C S Synthetic Biology, 11(5). https://doi.org/10.1021/acssynbio.1c00608

Fuertes, M., Selas, A., Trejo, A., Knudsen, B. R., Palacios, F. & Alonso, C. (2022). Synthesis of hybrid phosphorated indenoquinolines and biological evaluation as topoisomerase I inhibitors and antiproliferative agents. Bioorganic and Medicinal Chemistry Letters, 57, [128517]. https://doi.org/10.1016/j.bmcl.2021.128517

Langousis, G., Cavadini, S., Boegholm, N., Lorentzen, E., Kempf, G. & Matthias, P. (2022). Structure of the ciliogenesis-associated CPLANE complex. Science Advances, 8(15), [eabn0832]. https://doi.org/10.1126/sciadv.abn0832

Gerlach, P., Garland, W., Lingaraju, M., Salerno-Kochan, A., Bonneau, F., Basquin, J., Jensen, T. H. & Conti, E. (2022). Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome. Molecular Cell, 82(13), 2505-2518.e7. https://doi.org/10.1016/j.molcel.2022.04.011

Braunger, K., Ahn, J., Jore, M. M., Johnson, S., Tang, T. T. L., Pedersen, D. V., Andersen, G. R. & Lea, S. M. (2022). Structure and function of a family of tick-derived complement inhibitors targeting properdin. Nature Communications, 13, [317]. https://doi.org/10.1038/s41467-021-27920-2

Hartmann, S., Ling, M., Dreyer, L. S. A., Zipori, A., Finster, K., Grawe, S., Jensen, L. Z., Borck, S., Reicher, N., Niedermeier, D., Jones, N. C., Hoffmann, S. V., Wex, H., Rudich, Y., Boesen, T. & Santl-Temkiv, T. (2022). Structure and Protein-Protein Interactions of Ice Nucleation Proteins Drive Their Activity. Frontiers in Microbiology, 13, [872306]. https://doi.org/10.3389/fmicb.2022.872306

Bisiak, F., Chrenková, A., Zhang, S. D., Pedersen, J. N., Otzen, D. E., Zhang, Y. E. & Brodersen, D. E. (2022). Structural variations between small alarmone hydrolase dimers support different modes of regulation of the stringent response. Journal of Biological Chemistry, 298(7), [102142]. https://doi.org/10.1016/j.jbc.2022.102142

Nielsen, J., Brandt, J., Boesen, T., Hummelshøj, T., Slaaby, R., Schluckebier, G. & Nissen, P. (2022). Structural investigations of full-length insulin receptor dynamics and signalling. Journal of Molecular Biology, 434(5), [167458]. https://doi.org/10.1016/j.jmb.2022.167458

Jensen, R. K., Pedersen, H., Lorentzen, J., Laursen, N. S., Vorup-Jensen, T. & Andersen, G. R. (2022). Structural insights into the function-modulating effects of nanobody binding to the integrin receptor α_Mβ₂. Journal of Biological Chemistry, 298(8), [102168]. https://doi.org/10.1016/j.jbc.2022.102168

Sahin, C., Østerlund, E. C., Österlund, N., Costeira-Paulo, J., Pedersen, J. N., Christiansen, G., Nielsen, J., Grønnemose, A. L., Amstrup, S. K., Tiwari, M. K., Rao, R. S. P., Bjerrum, M. J., Ilag, L. L., Davies, M. J., Marklund, E. G., Pedersen, J. S., Landreh, M., Møller, I. M., Jørgensen, T. J. D. & Otzen, D. E. (2022). Structural Basis for Dityrosine-Mediated Inhibition of α-Synuclein Fibrillization. Journal of the American Chemical Society, 144(27), 11949-11954. https://doi.org/10.1021/jacs.2c03607

Winkler, M. B. L., Nel, L., Frain, K. M., Dedic, E., Olesen, E. & Pedersen, B. P. (2022). Sterol uptake by the NPC system in eukaryotes: a Saccharomyces cerevisiae perspective. FEBS Letters, 596(2), 160-179. https://doi.org/10.1002/1873-3468.14253

Matzke, M., Toft, S., Bechsgaard, J., Pold Vilstrup, A., Uhl, G., Künzel, S., Tuni, C. & Bilde, T. (2022). Sperm competition intensity affects sperm precedence patterns in a polyandrous gift-giving spider. Molecular Ecology, 31(8), 2435-2452. https://doi.org/10.1111/mec.16405

Toth, A. E., Helms, H. C., Harazin, A., Johnsen, K. B., Goldeman, C., Burkhart, A., Thomsen, M. S., Kempen, P. J., Klepe, A., Lipka, D. V., Møller, P. L., Andresen, T. L., Nyegaard, M., Moos, T., Brodin, B. & Nielsen, M. S. (2022). Sortilin regulates blood-brain barrier integrity. The FEBS Journal, 289(4), 1062-1079. https://doi.org/10.1111/febs.16225

Murphy, K. M., Poretsky, E., Liu, H., Micic, N., Nyhuis, A., Bohlmann, J., Schmelz, E. A., Zerbe, P., Huffaker, A. & Bjarnholt, N. (2022). Shielding the oil reserves: The scutellum as a source of chemical defenses. Plant Physiology, 188(4), 1944-1949. https://doi.org/10.1093/plphys/kiac038

Talotta, R., Bahrami, S. & Laska, M. J. (2022). Sequence complementarity between human noncoding RNAs and SARS-CoV-2 genes: What are the implications for human health? B B A - Molecular Basis of Disease, 1868(2), [166291]. https://doi.org/10.1016/j.bbadis.2021.166291

Gockert, M., Schmid, M., Jakobsen, L., Jens, M., Andersen, J. S. & Jensen, T. H. (2022). Rapid factor depletion highlights intricacies of nucleoplasmic RNA degradation. Nucleic Acids Research, 50(3), 1583-1600. https://doi.org/10.1093/nar/gkac001

Bale, L. K., Schafer, M. J., Atkinson, E. J., Le Brasseur, N. K., Haak, A. J., Oxvig, C. & Conover, C. A. (2022). Pregnancy-associated plasma protein-A (PAPP-A) is a key component of an interactive cellular mechanism promoting pulmonary fibrosis. Journal of Cellular Physiology, 237(4), 2220-2229. https://doi.org/10.1002/jcp.30687

Alam, P., Holst, M. R., Lauritsen, L., Nielsen, J., Nielsen, S. S. E., Jensen, P. H., Brewer, J. R., Otzen, D. E. & Nielsen, M. S. (2022). Polarized α-synuclein trafficking and transcytosis across brain endothelial cells via Rab7-decorated carriers. Fluids and Barriers of the CNS, 19(1), 37. https://doi.org/10.1186/s12987-022-00334-y

Rattan, S. (2022). Physiological hormesis and hormetins in biogerontology. Current Opinion in Toxicology, 29, 19-24. https://doi.org/10.1016/j.cotox.2022.01.001

Cavassim, M. I. A., Baker, Z., Hoge, C., Schierup, M. H., Schumer, M. & Przeworski, M. (2022). PRDM9 losses in vertebrates are coupled to those of paralogs ZCWPW1 and ZCWPW2. PNAS (Proceedings of the National Academy of Sciences of the United States of America), 119(9), [e2114401119]. https://doi.org/10.1073/pnas.2114401119

Blanco, B., Ramírez-Fernández, Á., Bueno, C., Argemí-Muntadas, L., Fuentes, P., Aguilar-Sopeña, Ó., Gutierrez-Agüera, F., Zanetti, S. R., Tapia-Galisteo, A., Díez-Alonso, L., Segura-Tudela, A., Castellá, M., Marzal, B., Betriu, S., Harwood, S. L., Compte, M., Lykkemark, S., Erce-Llamazares, A., Rubio-Pérez, L. ... Álvarez-Vallina, L. (2022). Overcoming CAR-Mediated CD19 Downmodulation and Leukemia Relapse with T Lymphocytes Secreting Anti-CD19 T-cell Engagers. Cancer Immunology Research, 10(4), 498-511. https://doi.org/10.1158/2326-6066.CIR-21-0853

Gupta, K. J., Kaladhar, V. C., Fitzpatrick, T. B., Fernie, A. R., Møller, I. M. & Loake, G. J. (2022). Nitric oxide regulation of plant metabolism. Molecular Plant, 15(2), 228-242. https://doi.org/10.1016/j.molp.2021.12.012

Sanchez-Roman, I., Ferrando, B., Holst, C. M., Mengel-From, J., Rasmussen, S. H., Thinggaard, M., Bohr, V. A., Christensen, K. & Stevnsner, T. (2022). Molecular markers of DNA repair and brain metabolism correlate with cognition in centenarians. GeroScience, 44(1), 103-125. https://doi.org/10.1007/s11357-021-00502-2

Ung, K. L., Alsarraf, H., Kremer, L. & Blaise, M. (2022). MmpL3, the trehalose monomycolate transporter, is stable in solution in several detergents and can be reconstituted into peptidiscs. Protein Expression and Purification, 191, [106014]. https://doi.org/10.1016/j.pep.2021.106014

Meron, E., Thaysen, M., Angeli, S., Antebi, A., Barzilai, N., Baur, J. A., Bekker-Jensen, S., Birkisdottir, M., Bischof, E., Bruening, J., Brunet, A., Buchwalter, A., Cabreiro, F., Cai, S., Chen, B. H., Ermolaeva, M., Ewald, C. Y., Ferrucci, L., Florian, M. C. ... Scheibye-Knudsen, M. (2022). Meeting Report: Aging Research and Drug Discovery. Aging, 14(2), 532-543. https://doi.org/10.18632/aging.203859

Moeskjær, S., Skovbjerg, C. K., Tausen, M., Wind, R., Roulund, N., Janss, L. & Andersen, S. U. (2022). Major effect loci for plant size before onset of nitrogen fixation allow accurate prediction of yield in white clover. Theoretical and Applied Genetics, 135(1), 125-143. https://doi.org/10.1007/s00122-021-03955-3

Reimer, L., Haikal, C., Gram, H., Theologidis, V., Kovacs, G., Ruesink, H., Baun, A., Nielsen, J., Otzen, D. E., Li, J-Y. & Jensen, P. H. (2022). Low dose DMSO treatment induces oligomerization and accelerates aggregation of α-synuclein. Scientific Reports, 12, [3737]. https://doi.org/10.1038/s41598-022-07706-2

Duncan, C. J. A., Skouboe, M. K., Howarth, S., Hollensen, A. K., Chen, R., Børresen, M. L., Thompson, B. J., Stremenova Spegarova, J., Hatton, C. F., Stæger, F. F., Andersen, M. K., Whittaker, J., Paludan, S. R., Jørgensen, S. E., Thomsen, M. K., Mikkelsen, J. G., Heilmann, C., Buhas, D., Øbro, N. F. ... Mogensen, T. H. (2022). Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic. The Journal of Experimental Medicine, 219(6), [e20212427]. https://doi.org/10.1084/jem.20212427

Rasmussen, H. Ø., Otzen, D. E. & Pedersen, J. S. (2022). Induction, inhibition, and incorporation: Different roles for anionic and zwitterionic lysolipids in the fibrillation of the functional amyloid FapC. The Journal of Biological Chemistry, 298(2), [101569]. https://doi.org/10.1016/j.jbc.2022.101569

Jepsen, M. R., Østergaard, J. A., Conover, C. A., Wogensen, L., Birn, H., Krag, S. P., Fenton, R. A. & Oxvig, C. (2022). Increased activity of the metalloproteinase PAPP-A promotes diabetes-induced glomerular hypertrophy. Metabolism: Clinical and Experimental, 132, [155218]. https://doi.org/10.1016/j.metabol.2022.155218

Aminzadeh, A., Larsen, C. E., Boesen, T. & Jørgensen, R. (2022). High-resolution structure of native toxin A from Clostridioides difficile. EMBO Reports, 23(1), [e53597]. https://doi.org/10.15252/embr.202153597

Farzadfard, A., König, A., Petersen, S. V., Nielsen, J., Vasili, E., Dominguez-Meijide, A., Buell, A. K., Outeiro, T. F. & Otzen, D. E. (2022). Glycation modulates alpha-synuclein fibrillization kinetics: a sweet spot for inhibition. The Journal of Biological Chemistry, 298(5), [101848]. https://doi.org/10.1016/j.jbc.2022.101848

Schröder, S. K., Schüler, H. M., Petersen, K. V., Tesauro, C., Knudsen, B. R., Pedersen, F. S., Krus, F., Buhl, E. M., Roeb, E., Roderfeld, M., Borojevic, R., Almeida, J. L. & Weiskirchen, R. (2022). Genetic and Molecular Characterization of the Immortalized Murine Hepatic Stellate Cell Line GRX. Cells, 11(9), [1504]. https://doi.org/10.3390/cells11091504

Petersen, G., Shyama Prasad Rao, R., Anderson, B., Zervas, A., Seberg, O., Rasmusson, A. G. & Max Møller, I. (2022). Genes from oxidative phosphorylation complexes II-V and two dual-function subunits of complex I are transcribed in Viscum album despite absence of the entire mitochondrial holo-complex I. Mitochondrion, 62, 1-12. https://doi.org/10.1016/j.mito.2021.10.006