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After-work meeting about cryo-EM

After-work meeting about cryo-EM

  • Thursday 17 September 2020 at 16:00

DUE TO THE CORONA VIRUS, THE EVENT HAS BEEN POSTPONED.

When a new date is chosen, it can be found on this page.

ALUMNI EVENT

The Department of Molecular Biology and Genetics invites all AU alumni with an interest in molecular biology to an after-work meeting about cryo-electron microscopy (cryo-EM).

Cryo-EM is a versatile technique of growing popularity and accessibility that can be used for macromolecular structure determination. In brief, a sample solution is snap-frozen on a grid-mesh at approximately -180°C. In the microscope, a beam of electrons interacts with the thin sample, which projects an image of the sample onto a detector, and from thousands of these 2-D projections, a 3-D reconstruction of the sample can be made.

Recent developments in detector technology and software algorithms have enabled the determination of biomolecules at atomic resolution in favorable cases, thus making cryo-EM an attractive alternative to NMR spectroscopy or X-ray crystallography without the need for crystallization. For this reason membrane proteins in particular are popular targets for cryo-EM.

At the after-work meeting, cryo-EM facility manager Thomas Boesen will give a short introduction to the technique and take the participants on a guided tour at the facility

Information about the cryo-EM facility.


Programme

16.00-16.30   Coffee/tea/light snack

16.30-17.00   Introduction to cryo-EM

17.10-18.00   Tour at the facility in two groups

18.00-19.00   Sandwich with soda/beer

19.00              End of meeting

 

Place

Department of Physics (details to be announced)

 

Date

Thursday 17 September 2020

 

Registration

The number of participants is limited to 20 and the seats are distributed on a first-come, first-served basis.

Please sign up at the following link no later than Tuesday 15 September 2020.