News

News

Ulf Ørom  has awarded the prestigious Hallas-Møller Investigator Grant valued at DKK 11 million to study the role of miRNA biogenesis in cancer. The project will be carried out at the Department of Molecular Biology and Genetics, Aarhus University. Photo: Mette Ørom.

2017.04.25 | Grant

Talented researcher receives DKK 11 million for research that may lead to better treatment of cancer

The Novo Nordisk Foundation has awarded the prestigious Hallas-Møller Investigator Grant valued at DKK 11 million to Ulf Andersson Ørom to study the role of miRNA biogenesis in cancer. The project will be carried out at the Department of Molecular Biology and Genetics, Aarhus University.

Immunohistochemical staining of liver biopsy specimens. Inflammatory cells are more numerous in the portal tracts and liver lobules of patients with the CC genotype at rs12979860 than in patients with the CT/TT genotype, while there was no difference according to IFN-λ4 activity. (a–c) (original magnifications, 200×). Photos: Storr Liver Centre, Australia.

2017.04.19 | Research

Mapping of genetic properties affecting the degree of liver injury

An international research team led by Professor Jacob George of Storr Liver Centre in Sydney, Australia - with the participation of researchers from Aarhus University Hospital and Aarhus University - has mapped the human genetic properties affecting the degree of liver injury in patients with hepatitis C virus infection.

Jørgen Kjems

2017.04.19 | Grant

Jørgen Kjems Director of new Danish National Research Foundation Center

A new basic research centre – CellPAT – will identify how cells ‘talk’ to each other, and thereby make it possible to prevent or correct the type of communication errors that lead to illness.

Poul Nissen, Sadegh Nabavi, Hanne Poulsen and Magnus Kjærgaard.

2017.04.19 | Grant

Four researchers from MBG participate in a new Danish National Research Foundation Centre

Together with Anders Nykjær (Centre Director) and Marco Capogna from the Department of Biomedicine, Poul Nissen, Sadegh Nabavi, Hanne Poulsen and Magnus Kjærgaard from MBG/DANDRITE/iNANO receive DKK 62 million to start the Center for Proteins in Memory (PROMEMO).

Thomas Boesen

2017.04.19 | Grant

Thomas Boesen participates in a new Danish National Research Foundation Centre

Together with Lars Peter Nielsen (Centre Director), Nils Risgaard-Petersen and Andreas Schramm from Bioscience, Elena Ferapontova, iNANO and Filip Meysman, AIAS, Thomas Boesen from MBG receive DKK 56 million for the Center for Electromicrobiology.

Postdoc Dennis V. Pedersen (seated), who was the driving force behind the new scientific results concerning our immune system, surrounded by his PhD supervisor Gregers Rom Andersen and the two PhD students Rasmus K. Jensen og Trine A.F. Gadeberg, who assisted Dennis with his work. In the picture, Dennis explains his colleagues how he has prepared an important reagent for the continued studies of the properdin protein. Photo: Lisbeth Heilesen.

2017.04.07 | Research

New research concerning an immune system accelerator leads the way for treatment of infections and cancer

New research results give an improved basic scientific understanding of how the innate immune system works, which – among other things – opens up for new possibilities for the treatment of various diseases.

In collaboration with the Carlsberg company, a group of Danish researchers will try to bring barley back to its original robust origin. Photo: Colourbox

2017.04.03 | Grant

Researchers recreate wild crops for the beer of the future

Over thousands of years, barley and wheat have been bred to such an extent that the yield has been greatly improved, but the crops have also lost a number of properties that are important to survive in the wild. A new Danish research project will restore the original properties of crops to make them more robust.

Scientists have developed a wheat with a specific ability to increase the digestibility of phosphorus and other important minerals. Photo: Janne Hansen

2017.03.30 | Research

Unique wheat passes the test

A unique, patented wheat can have significant importance to agriculture, the environment and undernourished people in developing countries. Animal tests recently demonstrated that this special wheat increases P and Ca digestibility.

The picture at the top shows a sperm cell with the head (cell body) and tail (also known as flagellum or cilium) that propels the sperm cell forward. The schematic in the middle shows how dynein motors (yellow stars) are transported via intraflagelar transport (IFT) and periodically distributed. The picture at the bottom illustrates how the ODA16 structure functions as an adaptor between the transport system and the dynein motors.

2017.03.27 | Research

Transport of molecular motors into cilia

Molecular motors produce the force that powers the beat of sperm cell tails to generate movement toward the egg cell for fertilization. New research now shows how the molecular motors that power the movement of sperm cells are recognized and specifically transported into the tail region of the cell. This knowledge can pave the way for a better…

The RedHill team assembled in Denmark. From left to right: Terry F. Plasse (MD, Medical Director, ReHill Biopharma), Danielle T. Abramson (Ph.D., Director, Intellectual Property and Research, RedHill Biopharma), Mark L. Levitt, (MD, Ph.D., Medical Director, Oncology, RedHill Biopharma), Emil Oldenburg (M.Sc., Scientific Assistant, Aarhus University), Christine R. Schar (Ph.D., Postdoctoral Fellow, Aarhus University) and Jan K. Jensen (Ph.D., Project Manager, Aarhus University).

2017.03.23 | Grant

Danish researchers and Israeli biopharmaceutical company collaborate to develop anti-cancer drugs

The Israeli Biopharmaceutical company RedHill Biopharma Ltd. (NASDAQ: RDHL) (Tel-Aviv Stock Exchange: RDHL) has extended its collaboration with researchers at Aarhus University in order to develop a potentially promising drug candidate for cancer treatment. The drug candidate is based on a protease inhibitor molecule - an area the Danish…

Model for monitoring and repairing damaged DNA (left figure). The crystal structure of the DNA control protein Rad26 that is responsible for bringing the Rad3 kinase to damaged DNA and starting repair signalling (right figure).

2017.03.20 | Research

Structural knowledge of the DNA repair complex

New Danish research provides mechanistic insight into how DNA is monitored and repaired if damage occurs. The results may eventually help to improve the treatment of certain types of cancer, as the DNA repair complex provides a mechanism for cancer cells to resist chemotherapy.

Model for RNA fate decisions: Early during its production by PolII, the CBC-bound cap of the emerging RNA is contacted by ‘productive’ (PHAX) and ‘destructive’ (ZC3H18) factors. These proteins form mutually exclusive complexes with the CBC until a ‘decision point’ (e.g. a terminator) is encountered by PolII, after which RNA fate is determined by stable interaction with either PHAX or ZC3H18.

2017.03.15 | Research

Sorting RNA for production or decay

Our genomes are promiscuously transcribed into RNA. How cells manage to sort this massive genomic output into functional and non-functional material has remained enigmatic. New research describes protein interactions involved in such RNA fate determination.

Adult zebrafish in the zebrafish facility at the Department of Molecular Biology and Genetics, Aarhus University, Denmark. Zebrafish in the wild are found in northeastern India, Bangladesh and Nepal in standing and slow flowing water in ditches, rice fields and ponds. The Latin name Danio reportedly comes from the word Dhani, which is Bengali for "from the rice fields." Photo: Lisbeth Heilesen.
The zebrafish facility at the Department of Molecular Biology and Genetics, Aarhus University, Denmark. Zebrafish take up less space on the shelves than mice. Photo: Kasper Kjær-Sørensen. Click photos for enlargement.
Zebrafish embryos are transparent. Here is a 24-hour old embryo as it appears in an ordinary light microscope. In addition to external structures such as yolk sac, head and eye, you can also see the brain, the inner ear and the V-shaped somites, which are the precursors of the V-shaped skeletal muscle. Photo: Kasper Kjær-Sørensen.
A 72-hour old transgenic embryo with green fluorescent protein (GFP) in the endothelial cells lining blood and lymphatic vessels. All vessels are clearly highlighted in the living body. Note that due to the high density of vessels surrounding the gills, the underside of the head appears overexposed in the image. Photo: Kasper Kjær-Sørensen.
Microinjection in newly fertilized embryos. The depicted embryos are about 30 minutes old. The first cell being formed can be seen at the bottom of the embryo near the top of the image. Photo: Kasper Kjær-Sørensen.

2017.03.03 | Research

The zebrafish is an important animal model

Humans and zebrafish have more in common than you would think. Therefore, zebrafish are used more and more, for example, to study the function of genes, to create animal models for human diseases and to develop new human drugs.

Poul Nissen is receiving the 2017 Novo Nordisk Prize for his pioneering studies of the structure and function of ion pumps. Photo: Novo Nordisk Fonden.

2017.02.10 | Awards

Professor Poul Nissen receives the 2017 Novo Nordisk Prize

Poul Nissen, Professor at Aarhus University, is receiving the 2017 Novo Nordisk Prize for his pioneering studies of the structure and function of ion pumps. Through his research, Poul Nissen has clarified in detail, among other things, how ions and nutrients are transported into and out of cells. This fundamental knowledge is very significant for…

Researchers from Aarhus University and the seed company DLF were awarded a grant from the  the Innovation Fund Denmark of DKK 11 million to combine strong features of existing grass species by new breeding techniques and thereby develop a new grass variety that is more robust than the existing ones. Photo: Biopix (http://www.biopix.dk)

2017.02.09 | Grant

New breeding strategy to increase the export of Danish grasses

The best properties from three well-known grasses will be united in new grass varieties. With significantly enhanced performance and high robustness, such grasses will pave the way for Danish export of new varieties that are prepared for future climate and the demand for more biomass.

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