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In collaboration with international research groups, a Danish research team from Aarhus University has found a mechanism that helps the cells prevent accumulation of the many useless RNA molecules being constantly produced by runaway gene activity in our cells. These findings contribute to a new understanding of our genes and may eventually help our understanding of gene activity in stem cells and cancer. From left: Torben Heick Jensen, Michal Domanski and Peter Refsing Andersen (Photo: Lisbeth Heilesen)

2013.11.24 | Public / media, Department of Molecular Biology and Genetics

Proteins suppress useless gene activity in human cells

A new study shows how our cells sort the wheat from the chaff in a tangle of useful and useless gene molecules. In collaboration with international research groups, a Danish research team from Aarhus University has now found a mechanism that helps the cells prevent accumulation of the many useless RNA molecules being constantly produced by runaway…

The Nano Creators study Nanoscience, Molecular Biology or Chemistry at Aarhus University. The team consists of Ane Helene Langvad Andreassen, Minh Lon Lu, Caroline Filippa Langfeldt Knabe, Malthe Hansen-Bruun, Mikkel Bach Skovsgaard, Nadia Nasser Petersen, Veronica Liv Andersen and Julie Stokkebro Schmøkel.
Nano Creators with their prize at Harvard. (Copyright BIOMOD)

2013.11.20 | Public / media, Department of Molecular Biology and Genetics

Students win the hearts of the audience

A team of Aarhus students – Nano Creators – won the Audience Choice Award for their Bachelor’s project at Harvard University’s bio-molecular design competition. The Nano Creators combined good research with creative communication.

The figure shows the bacterial 70S ribosome with the cleavage point for the cytotoxin VapC20 marked with red. To the right is transfer RNA, which is cleaved by a similar mechanism in the pathogenic organism <em>Shigella flexneri</em>. Behind this is an RNA gel showing the actual cleavage reaction in the ribosome (Figure: Ditlev E. Brodersen). Click figure for enlargement

2013.11.18 | Department of Molecular Biology and Genetics, Public / media

Bacteria use lethal cytotoxins to evade antibiotic treatment

Bacteria that cause infectious diseases produce a number of cytotoxins, and an international research team has now found the mechanism behind one of these toxins. The new results could make it possible in future to develop new treatment methods to impair the cytotoxic activity and thereby reduce the severity of infectious diseases.

[Translate to English:] Pontus Gourdon fra Institut for Molekylærbiologi og Genetik på Aarhus Universitet har netop modtaget Lundbeckfondens fellowship. (Foto: Lundbeckfonden)

2013.11.15 | Public / media, Department of Molecular Biology and Genetics

When human cells are unable to protect themselves

Pontus Gourdon, Department of Molecular Biology and Genetics, has just been awarded a Lundbeck Foundation Fellowship, and he will study what happens when the transport of substances in and out of the cells does not work. Dreaded dementia diseases can occur if there is an imbalance in a number of substances in human cells.

An international team of researchers under Danish leadership is the first in the world to culture and purify an interferon that in due course could contribute to greater success in treating Hepatitis C. From left: Rune Hartmann, Ewa Terczynska-Dyla and Ole J. Hamming. (Photo: Lisbeth Heilesen)
The body produces the interferon IFN? during a viral infection. The family includes IFN?3 and, in some people, IFN?4. By studying how much intracellular and extracellular IFN?3 and IFN?4 exist, the Aarhus University research team discovered that the cells release much more IFN?3 than IFN?4. (Figure: Ole J. Hamming)

2013.11.12 | Public / media, Department of Molecular Biology and Genetics

Protein with potential role in the fight against hepatitis C virus

An international team of researchers under Danish leadership is the first in the world to culture and purify an interferon (protein) called lambda 4 (IFNλ4) – a protein that behaves like Dr Jekyll and Mr Hyde. Paradoxically, it increases the risk of getting hepatitis C (HCV) and reduces the chances of being cured, but nevertheless has a…

Anne von Philipsborn and Mark Denham have been appointed group leaders at DANDRITE (Photos: private)

2013.11.12 | Public / media, Department of Molecular Biology and Genetics

DANDRITE appoints the first two research group leaders

DANDRITE has appointed Anne von Philipsborn and Mark Denham as Group Leaders. These appointments are the first two in a series of five group leaders to be employed at DANDRITE. Mark and Anne will start their research in December and January, respectively.

2013.11.11 | Public / media, Department of Molecular Biology and Genetics

The description of the sodium-potassium pump among the 10 best research results in 2013

In September, Poul Nissen's research group published the description of the sodium-potassium pump in Science. Videnskab.dk has now nominated these results to be among the 10 best research results in 2013.