Norwegian-Danish collaboration uncovers proton channel in a bacterial enzyme


The Danish research team behind the new results (from left): Jan K. Jensen, Michael Etzerodt, Anette Kjems and Bjarne Jochimsen (photo: Lisbeth Heilesen)
The Norwegian research team: Kaare Bjerregaard-Andersen, J. Preben Morth and Theis Sommer (photo: Oslo University)
Identification of two entrances to the active site, a combined water and proton channel and a substrate and product channel (figure: Kaare Bjerregaard-Andersen)

2014.06.30 | Research

Norwegian - Danish collaboration uncovers proton channel in a bacterial enzyme

A scientific collaboration between researchers from the University of Oslo and Aarhus University has revealed an unexpected channel for removal of protons in the enzyme isatin hydrolase.

At the beginning of an infection, the viral RNA is released inside the cell. The cellular protein RIG-I detects the viral RNA and initiates a defence mechanism that leads to the expression of the protein OASL. Later during the infection – when OASL is present in the infected cell – RIG-I recognises the viral RNA again , but by interacting with OASL, the initiated defence mechanism is enhanced, thereby fending of the virus more efficiently.

2014.06.23 | Public / media

Viral infections could be stopped by boosting natural protein

An international research team has published results showing that boosting the protein OASL may help the body to detect and fend off certain viral infections on its own. The discovery could lead to new, more effective treatments for many dangerous viruses such as hepatitis C and influenza.

2014.06.23 | Awards

Thomas Birkballe receives ST Science Award 2014

During ST's summer celebration on 20 June 2014, six ST awards were given. Postdoc Thomas Birkballe Hansen from MBG/iNANO received the ST Science Award.

Bjørn Panyella Pedersen (Photo: the Danish Council for Independent Research)

2014.06.18 | Public / media

Sapere Aude grant awarded to Bjørn Panyella Pedersen

With a Sapere Aude Starting Grant of more than DKK 7 million from the Danish Council for Independent Research, Bjørn P. Pedersen is assured of the best possible chance to return to Denmark and establish a structural biology research group at Aarhus University.

2014.06.18 | Public / media

Six researchers from MBG receive grants from the Danish Coucil for Independent Research

Jan J. Enghild, Kim Henrik Hebelstrup, Ian Max Møller, Lene Niemann Nejsum, Daniel Otzen and Claus Oxvig from MBG have all received large grants from The Danish Council for Independent Research.

Showing results 1 to 5 of 218

1 2 3 4 5 6 7 8 9 10 Next


7th European Workshop on Plant Senescence

Researchers from MBG organise an international plant conference on
Plant Senescence and Productivity at Sandbjerg Estate during the period
10-14 November 2014.

More information and registration


Thu 14 Aug
09:00-10:30 | Flakkebjerg, the Auditorium
Møde med rektor/Meeting with Rector - MBG-Flakkebjerg
Thu 14 Aug
13:00-15:00 | MOMAs auditorium
Master's degree exam: Bjarke Primdal-Bengtson: Construction of a Sleeping Beauty Based Vector System for an Inducible Expression of Rab27b; a Regulator of Exosome Release
Vejleder: Marie Stampe Ostenfeldt
Fri 15 Aug
09:00-16:30 | Per Kirkeby Auditorium, The Lakeside Lecture Theatres ("Søauditorierne")
Instituttets årsmøde (Annual meeting of the department)
Thu 21 Aug
14:15-15:00 | Auditorium to be announced
MBG Hot Topic Talk: Christian Kroun Damgaard: DDX6 regulates sequestered nuclear CUG-expanded DMPK-mRNA in dystrophia myotonica type 1

Lecture series at MBG

Comments on content: 
Revised 2014.07.07

How to find the Department of Molecular Biology and Genetics

Show detailed map


The Department of Molecular Biology and Genetics (MBG)
is located at five different addresses:

  • The Science Park - Gustav Wieds Vej 10, 8000 Aarhus C, Denmark
  • Biokæden (Campus) - C.F. Møllers Allé 3, 8000 Aarhus C, Denmark
  • iNANO - Gustav Wieds Vej 14, 8000 Aarhus C, Denmark
  • Foulum - Blichers Allé 20, 8830 Tjele, Denmark
  • Flakkebjerg - Forsøgsvej 1, 4200 Slagelse, Denmark

More information on how to find these places and who works where

Contact information

at the Department of Molecular Biology and Genetics

Tel.: +45 8715 0000
CVR-no.: 31119103
VAT ("moms") number: 31 11 91 03
EAN-no. 5798000419964
"Stedkode" (departmental id number): 2802

Internal information

For staff and students at
the Department of Molecular Biology and Genetics

Aarhus University
Nordre Ringgade 1
DK-8000 Aarhus C

Tel: +45 8715 0000
Fax: +45 8715 0201

CVR no: 31119103

AU on social media