New discovery from the molecular machinery for depression and addiction

News

The bacterial transporter whose molecular structure has been solved uses the same transport mechanism as the neurotransmitter transporters but instead transports amino acids, such as leucine (Leu). In the outward-oriented state (left) Leu (yellow spheres) binds to two sodium ions (green spheres) in a central binding pocket whereas the rotating unit, designated L25 (beige spheres), is located next to the binding pocket of the  transported substance. In the new empty state (right) which the Aarhus researchers have now identified, L25 rotates into the binding pocket where it mimics and compensates for the lacking substance and sodium ions, enabling the transporter to return to an outward-oriented state from which it can start a new transport cycle.  Figure: Lina Malinauskaite.

2016.05.26 | Research

New discovery from the molecular machinery for depression and addiction

Researchers at Aarhus University have described how a group of the brain’s transport proteins with important roles in depression and dependence overcome the step which limits their effectiveness. The discovery makes it possible to describe the full function of the transport protein and can provide better opportunities for counteracting the effect…

Mogens Duch

2016.05.23 | People

Obituary for Senior Researcher Mogens Duch (1958-2016)

Mogens Duch, senior researcher at the Department of Molecular Biology and Genetics, died suddenly on Friday 20 May 2016, aged 58.

Schematic represention of agotron biogenesis and function. Agotrons are derived from short introns produced during RNA splicing. Upon association with Ago proteins, agotrons target and destabilize mRNAs in a miRNA like manner. Figure: Thomas Birkballe Hansen.

2016.05.18 | Research

Agotrons – a new class of small regulatory molecules

Danish and American researchers have found a novel subclass of small RNA molecules involved in the regulation of gene expression.

Showing results 1 to 3 of 249

1 2 3 4 5 6 7 8 9 10 Next

PhD defences

Agnieszka Jendroszek

2016.05.27 | Talent development

Agnieszka Jendroszek: Co-evolution of a serine protease, its protein substrate and its serpin inhibitor

PhD defence, Friday 27 May 2016. Agnieszka Jendroszek.

Maja Holch Nielsen

2016.05.24 | Talent development

Maja Holch Nielsen: Structural studies of the antioxidant protein TSA2

PhD defence, Tuesday 24 May 2016. Maja Holch Nielsen

Malene Runge Jepsen

2016.05.20 | Talent development

Malene Runge Jepsen: Identifying the mechanism behind Stanniocalcin-mediated growth reduction

PhD defence, Friday 20 May 2016. Malene Runge Jepsen.

Showing results 1 to 3 of 162

1 2 3 4 5 6 7 8 9 10 Next

Project day for Bachelor and Master students

The Department of Molecular Biology and Genetics holds a "Project Day", where researchers at the department will present their bachelor and thesis project for students in Molecular Biology:

  • Monday 30 may 2016 at 14:00-15:30
    The Old Canteen, Pavillon 1, Gustav Wieds Vej 10 in the Science Park (building 3140).

See the list of projects.

Calendar

Mon 30 May
14:00-15:30 | The old canteen in Pavilion 1 in the Science Park in building 3140
Project day for Bachelor and Master projects
Fri 10 Jun
09:00-16:00 | The Lakeside Lecture Theatres ("Søauditorierne") - Per Kirkeby Auditorium
MBG's Annual Meeting (Årsmøde) - Day Event
Fri 10 Jun
18:30-02:00 | "Stakladen" (AU main canteen), building 1423
MBG's Annual Meeting (Årsmøde) - Dinner and party
Fri 28 Oct
08:30-20:00 | Himmerland Golf and Spa Resort
PhD Conference (mandatory for all MBG PhD students)

Comments on content: 
Revised 2016.05.26