Jeanette Hedegaard Jensen: Gene expression in skeletal musculature affected by unaccustomed physical exercise
PhD defence, Friday 13 April 2012. Jeanette Hedegaard Jensen.
News-itemDuring the course of her PhD studies, Jeanette Hedegaard Jensen carried out research into which genes in porcine skeletal musculature have an impact on muscle recovery immediately after unaccustomed physical activity, as well as which genes are important for the satellite cells in the muscles.
She studied the activity of thousands of genes in porcine muscle in the first three hours following unaccustomed physical activity in the form of a single session of running. The activation of skeletal muscle stem cells – also called satellite cells – plays an important role in the repair of damage to the musculature. Such damage can occur as a result of unaccustomed strain on the musculature. Gene expression in active satellite cells was therefore also studied. The research results achieved by Jeanette Hedegaard Jensen contribute to the understanding of which genes are important for the early muscle response to unaccustomed physical activity, as well as which genes are involved in the ability of the satellite cells to repair the skeletal musculature.
Time: Friday 13 April 2012 at 13.00
Place: Eduard Bierman Lecture Theatre, Lakeside Lecture Theatres, Aarhus University
Title of dissertation: Transcriptome profiles in porcine skeletal muscles in response to acute physical exercise and in porcine primary satellite cells during myogenesis
Contact information: Jeanette Hedegaard Hansen, jeanette.hansen@agrsci.dk, +45 2812 0324
Members of the assessment committee:
Senior Scientist Peter Schjerling, Department of Sports Medicine, Bispebjerg Hospital, Copenhagen
Professor Claire Stewart, Institute for Biomedical Research into Human Movement and Health, Manchester Metropolitan University, UK
Associate Professor Ernst-Martin Füchtbauer, Department of Molecular Biology and Genetics, Aarhus University
Main supervisor:
Associate Professor Bjarne Juul Bonven, Department of Molecular Biology and Genetics, Aarhus University
Co-supervisor:
Associate Professor Bo Thomsen, Department of Molecular Biology and Genetics, Aarhus University
Language: The dissertation will be defended in English
The defence is public.
The dissertation is available for reading at the Graduate School of Science and Technology / GSST, Ny Munkegade 120, building 1521, room 112, 8000 Aarhus C.