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Latest peer-reviewed publications at MBG

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Lee, H., Ko, K., Kim, S., Lee, G., Kim, S., Lee, J., Song, D. Y., Bong, G., Han, J. H., Lee, J., Kim, Y. R., Lee, Y., Kim, E., Børglum, A. D., Grove, J., Kim, S. H., Sun, W., Yoo, H. J. & An, J. Y. (2026). Co-occurrence of rare variants implicates gene pairs in cytoskeletal pathways and is associated with increased severity in autism spectrum disorder. Genome Biology, 27(1), Article 147. https://doi.org/10.1186/s13059-026-04041-x

Astono, J., Jørgensen, A. G., Bus, C., Nielsen, S. D. H., Kjems, J. & Sundekilde, U. K. (2026). Global protein profiling of human milk using pre-enriched RNA-sequence libraries. Scientific Reports, 16(1), Article 11827. https://doi.org/10.1038/s41598-026-41374-w

Gordon, M., Akyol, T. Y., Amos, B., Andersen, S. U. & Williams, C. (2026). KeySDL: sparse dictionary learning for keystone microbe identification from steady-state observations using a dynamical-systems model. BioData Mining, 19(1), 18. Article 18. https://doi.org/10.1186/s13040-026-00527-3

Aagaard, J. B., Gandini, R., Ballegaard, A.-S. R., Krogstrup Jensen, B., Dorn, B., Verner, A., Lenstrup, A., Sønderholm, M., Miehe, M., Pfützner, W., Jakob, T., Andersen, G. R., Möbs, C. & Spillner, E. (2026). Nanobody-based IgG simultaneously inhibit the allergenic and enzymatic activity of the dominant honeybee venom allergen. Nature Communications, 17(1), Article 1814. https://doi.org/10.1038/s41467-026-69572-0

Cho, H., Nielsen, M. L. & Olsen, J. V. (2026). Quantitative proteomics and phosphoproteomics reveal glucocorticoid stimulation of TLR and Rho GTPase signaling in neutrophil-like cells. Genome Biology, 27(1), Article 77. https://doi.org/10.1186/s13059-026-03985-4

Bicer, D., Matsuoka, R., Moumbock, A. F. A., Sukumar, P., Suades, A., Cheruvara, H., Quigley, A., Drew, D., Pardon, E., Steyaert, J., Henderson, P. J. F., Caffrey, M., Griese, J. J. & Nji, E. (2026). Structural basis of specific lysine transport by Pseudomonas aeruginosa permease LysP. Nature Communications, 17(1), Article 37. https://doi.org/10.1038/s41467-025-66618-7

Pečnerová, P., Ishida, Y., Garcia-Erill, G., Bertola, L. D., Santander, C. G., Liu, X., Brüniche-Olsen, A., Khan, A., Hennelly, L. M., Balboa, R. F., Lin, L., Rasmussen, M. S., Wang, X., Schubert, M., Al-Chaer, A., Urbaniak, S., Nobuta, K., Treadup, S., Viaud-Martinez, K. A. ... Roca, A. L. (2026). The genomic impact of population connectivity and decline in Africa’s elephants. Nature Communications, 17(1), Article 3223. https://doi.org/10.1038/s41467-026-71262-w

Cerda-Jara, C. A., Scoyni, F., Zolotarov, G., Bhaskar, P., León-Periñán, D., Kjems, J. & Rajewsky, N. (2026). The history and function of a circular RNA. Nature Communications, 17(1), Article 3862. https://doi.org/10.1038/s41467-026-71822-0

Hui, T. Y. J., Epopa, P. S., Millogo, A. A., Yao, F. A., Koulmaga, D., Noulin, F., Diabate, A. & Burt, A. (2026). Variance partitioning reveals contrasting random effect contributions to the density and species composition of malaria-transmitting mosquitoes in western Burkina Faso. Parasites and Vectors, 19(1), Article 235. https://doi.org/10.1186/s13071-026-07406-0

Şen, A., Karaman, E., Heegaard, C. W., Poulsen, N. A. & Buitenhuis, A. J. (2026). Predicting riboflavin (vitamin B₂) and cobalamin (vitamin B₁₂) concentrations in Danish cow milk using Fourier transform mid infrared spectra. International Dairy Journal, 179, Article 106656. https://doi.org/10.1016/j.idairyj.2026.106656

Clowes, K. A., Andersen, C. G., Chrenková, A. & Pedersen, B. P. (2026). Sugar rush: Structural breakdown of plant sugar transport. Current Opinion in Structural Biology, 99, Article 103295. https://doi.org/10.1016/j.sbi.2026.103295

Nel, L., Driller, J. H., Driller, R., Frain, K. M. & Pedersen, B. P. (2026). Structural and biochemical comparison of the FLVCR and CTL membrane protein families in eukaryotes. Life Science Alliance, 9(7), Article e202503583. https://doi.org/10.26508/lsa.202503583

Lopez-Aguileta, L., Martín-Encinas, E., Knudsen, B. R., Tesauro, C., Schirizzi, A., Montanaro, R., D'Alessandro, R., Perrone, M. G., Stefanachi, A., Contino, M. & Alonso, C. (2026). Synthesis and biological evaluation of novel fused pyridopyrimidine derivatives as topoisomerase I inhibitors and as potential antitumor agents: promising results in lung, ovary and gastric cancer. European Journal of Medicinal Chemistry, 310, Article 118782. https://doi.org/10.1016/j.ejmech.2026.118782

Yan, K., Stanley, M., Raimi, O., Ferenbach, A. T., Dorfmueller, H. C. & van Aalten, D. M. F. (2026). Cell wall target fragment discovery using a low-cost, minimal fragment library. FEBS Letters, 600(11), 1638-1654. https://doi.org/10.1002/1873-3468.70281

Goto, T., Andersen, K. R., Bamba, M., Sato, S., Sugawara, M., Minamisawa, K., Kawaguchi, M., Stougaard, J. & Kawaharada, Y. (2026). Cyclophilin A-mediated cis/trans isomerization modulates RIN4 to control intracellular rhizobial infection in legumes. New Phytologist, 250(6), 3932-3945. https://doi.org/10.1111/nph.71147

Harazin, A., Reinert, L. S., Alam, P., Hoy, L., Marnow, A. B., Nielsen, J., Lorentzen, A., Otzen, D. E., Paludan, S. R. & Nielsen, M. S. (2026). Double-Stranded DNA Sensing cGAS-STING Immune Signaling in a Rat Co-Culture Model of the Blood-Brain Barrier. Cell Biochemistry and Function, 44(6), e70240. https://doi.org/10.1002/cbf.70240

Menaceur Vandenbroucke, C., Scavenius, C. & Hayashi, Y. (2026). EV-SPEC: Decoding the Spatial Proteomic Signature of the Extracellular Vesicle Corona. Journal of Extracellular Biology, 5(6), Article e70151. https://doi.org/10.1002/jex2.70151

Kristjánsdóttir, N., Thorsen, K., Birkbak, N. J. & Dyrskjøt, L. (2026). Immune profiling of T cells: A comparative analysis of single-cell TCR sequencing using 10X Genomics and Parse Biosciences platforms. Biochemistry and Biophysics Reports, 46, Article 102592. https://doi.org/10.1016/j.bbrep.2026.102592

Gierlich, S. A., Jayakody, T. B., Augustine, S. M., Liu, H., Jääskeläinen, M., Vaisalu, T., Snowdon, R. J. & Andersen, S. U. (2026). Progress and Challenges in Faba Bean Genetic Engineering. Legume Science, 8(2), Article e70123. https://doi.org/10.1002/leg3.70123

Stambler, I., Tietz-Latza, A., Schumacher, B., Geiger, H., Morrison, H., Tüscher, O., Fuellen, G., Meisel, R., Simm, A., Pfeiffer, A., Steinhage, A., Popa-Wagner, A., Wagner, W., Cornely, O., Krause, M., Mitrou, G., Kyriazis, M., Scheibye-Knudsen, M., Rattan, S. ... Gonos, E. S. (2026). The need to increase support for healthy ageing and longevity research in the EU by establishing a Coordination and Support Programme on Healthy Ageing and Longevity. Mechanisms of Ageing and Development, 231, Article 112187. https://doi.org/10.1016/j.mad.2026.112187

Marquart Løber, I. M., Ward, L. J., Elmsjö, A., Söderberg, C., Villesen, P., Nielsen, K. L. & Green, H. (2026). Human-to-Rat Validation of PMI Biomarkers: A Bidirectional Cross-Species Metabolomics Study Reveals Asymmetric Translation. Analytical Chemistry, 98(20), 14883-14890. https://doi.org/10.1021/acs.analchem.6c00202

Birkbak, N. J., TRACERx Consortium, TRACERx EVO Consortium & PEACE Consortium (2026). Evolutionary characterization of lung cancer metastasis. Nature, 653(8115), 911-922. https://doi.org/10.1038/s41586-026-10428-4

Lennartsson, C., Kyriakidou, P., Nielsen, M. L., Olsen, J. V., Cox, J. & Hendriks, I. A. (2026). Improved peptide search for identification of SUMO and sequence-based modifications, in MaxSBM. Molecular & Cellular Proteomics : MCP, Article 101589. Advance online publication. https://doi.org/10.1016/j.mcpro.2026.101589

Demaegd, K. C., Kool, L., Baindoor, S., Donovan, P. D., Su, J., Westeneng, H. J., van Eijk, R. P. A., Geoghegan, G., Perez Morrissey, E., Halang, L., Poesen, K., Masrori, P., Gibriel, H. A. Y., Jirström, E., Venø, M. T., Kjems, J., Hardiman, O., Veldink, J. H., Kenna, K. ... van Es, M. A. (2026). Small RNA sequencing identifies serum tDR-1:34-Gly-GCC tiRNA levels as a biomarker for survival in amyotrophic lateral sclerosis. iScience, 29(5), Article 115636. https://doi.org/10.1016/j.isci.2026.115636

Djavani-Tabrizi, I., Lindkvist, T. T., Otzen, D. E. & Nielsen, S. B. (2026). When motion slows: intrinsic photophysics of thioflavin T and X cations at cryogenic temperatures. Physical Chemistry Chemical Physics, 28(18), 11181-11186. https://doi.org/10.1039/d6cp00731g

Nakajima, R., Yamamoto, S., Kawamura, Y. K., Kitazawa, T., Kimura, M. & Kitazawa, Y. (2026). Design, Synthesis, and Evaluation of an Ammonium-Terminated Superchaotropic Boron Cluster: Effects on the Transmembrane Delivery of Neutral and Charged Cargos. Inorganic Chemistry, 65(18), 9728-9733. https://doi.org/10.1021/acs.inorgchem.5c05467

Carneiro, I. S. M., Pedrosa, L. R. R., Corrêa, A. C. R., Soares, B. G. C., Rocha, L. S. O., Leal, L. C. P., Passos-Monteiro, E. & Krejcová, L. V. (2026). Dance therapy improves the joint range of motion in people with Parkinson’s disease: an essay with the Baila Parkinson method. Brazilian Journal of Motor Behavior, 20(1), Article e536. https://doi.org/10.20338/bjmb.v20i1.526

Lorentzen, J., Fruergaard, M. U., Lukácsi, S., Jørgensen, M. H., van Veghel, T. L. G., Jensen, R. K., Pietrzak-Lichwa, K. J., Bajtay, Z., Hořejší, V., Flygaard, R. K., Vorselen, D., Mortensen, S. A. & Andersen, G. R. (2026). Three cryo-EM structures of complement C3d-bound α_Mβ₂ reveal an unexpected layer of dynamics for αI-containing integrin receptors. Science Advances, 12(19), Article eaea7241. https://doi.org/10.1126/sciadv.aea7241

Adam, L., Molenkamp, W. H., Nowak, J. S., Farzadfard, A., Gaarthuis, K., Kumar, R., Nielsen, J., Otzen, D. E., Johansson, J. & Abelein, A. (2026). Mechanism-selective inhibition of α-synuclein aggregation by the chaperone-like BRICHOS domain. The Journal of Biological Chemistry, 302(6), 113117. Advance online publication. https://doi.org/10.1016/j.jbc.2026.113117

Winther, K. G., Schneider, J., Haas, G., Christensen, A. H., Goyal, S., Luo, W., Wei, Z., Liu, J., Kjøge, K., Enghild, J. J., Meignin, C., Silverman, N., Cai, H., Imler, J. L. & Hartmann, R. (2026). FADD is recruited to activated STING oligomers to initiate caspase-mediated NF-κB activation in Drosophila melanogaster. EMBO Journal, 45(9), 2965-2990. https://doi.org/10.1038/s44318-026-00761-9

Golbek, T. W., Rasmussen, M. H., Bregnhøj, M., Boesen, T., Drace, T., Faase, R., Baio, J. E. & Weidner, T. (2026). Binding and orientation of ice nucleating proteins on hydrophilic and hydrophobic surfaces probed by photoelectron spectroscopies. Biointerphases, 21(3), Article 031002. https://doi.org/10.1116/6.0005223

Faber, A. H., Bataillon, T. & Ehlers, B. K. (2026). Climate-Driven Convergence of Chemical Ecotypes in Mediterranean Lamiaceae. Journal of Biogeography, 53(5), Article e70247. https://doi.org/10.1111/jbi.70247

Walpole, S., Santiago-Vela, M. I., Birkedal, U., Hong, Z., Ros, X. B. D., van Overeem Hansen, T. & Wadt, K. A. W. (2026). Functional Analysis and Clinical Data Reclassify the DICER1 c.4206+1G>C Variant, Leading to Exon 22 Skipping, as Likely Pathogenic. Clinical Genetics, 109(5), 931-936. https://doi.org/10.1111/cge.70110

De Dios Andres, P., Garg, A., Alam, R., Westensee, I. N., Kjaergaard, M. & Städler, B. (2026). Transmembrane Condensation in Albumin-Loaded Giant Vesicles Induced by an Intrinsically Disordered Protein. ChemSystemsChem, 8(3), Article e00076. https://doi.org/10.1002/syst.202500076

Aliakbari, F., Rahmani, M., Marzookian, K., Boroujeni, N. N., Alikhanian, A., Ghasemi, F., Otzen, D. E. & Morshedi, D. (2026). Exosomes as Advanced Nanocarriers: Overcoming the Blood-Brain Barrier for Targeted Therapeutic Delivery in Neurodegenerative Diseases. Current drug delivery. Advance online publication. https://doi.org/10.2174/0115672018430706251211094801

Bernatz, S., Prudente, V., Pai, S., Attermann, A. K., Di Federico, A., Rowan, A., Veeriah, S., Dyrskjøt, L., Nürnberg, L., Alessi, J. V., Ott, P. A., Sharon, E., Hackshaw, A., McGranahan, N., Abbosh, C., Mak, R. H., Bitterman, D., Awad, M., Ricciuti, B. ... Aerts, H. J. W. L. (2026). Thymic health and immunotherapy outcomes in patients with cancer. Nature, 652(8111), 995-1003. https://doi.org/10.1038/s41586-026-10243-x

Bernatz, S., Prudente, V., Pai, S., Attermann, A. K., Cao, Y., Chen, J., Lyass, A., Foldyna, B., Nürnberg, L., Bressem, K., Abbosh, C., Swanton, C., Jamal-Hanjani, M., Lu, M. T., Murabito, J. M., Lunetta, K. L., Birkbak, N. J. & Aerts, H. J. W. L. (2026). Thymic health consequences in adults. Nature, 652(8111), 986-994. https://doi.org/10.1038/s41586-026-10242-y

Vinther, S. C., Resag, A., Le, K. T. T., Zelle-Rieser, C. C., Strandt, H., Malle, M. G., Christiansen, S. H., Del Frari, B., Stigger, T., Schilling, B., Wohlfarth, J., Thiel, S., Valero, J., Stoitzner, P. & Kjems, J. (2026). Targeting Langerhans cells using a modular mannosylated nucleic acid-based vaccine platform. Journal of Controlled Release, 392, 114741. Article 114741. https://doi.org/10.1016/j.jconrel.2026.114741

Liu, J., Yan, S., Li, M., Shen, D., Tichá, M., Bærentsen, R., Andersen, K. R., Verbeek, F., Kulikova, O., Geurts, R., Bisseling, T. & Huisman, R. (2026). Ancestral functionality and symbiotic refinement of NIN in root nodule symbiosis. Nature Communications, 17(1). https://doi.org/10.1038/s41467-026-71330-1

Vasilevsky, N. A., Toro, S., Matentzoglu, N., Flack, J. E., Mullen, K. R., Hegde, H., Gehrke, S., Whetzel, P. L., Shwetar, Y., Harris, N. L., Ngu, M. S., Alyea, G. L., Kane, M. S., Roncaglia, P., Sid, E., Thaxton, C. L., Wood, V., Abraham, R. S., Achatz, M. I. ... Haendel, M. A. (2026). Mondo: integrating disease terminology across communities. Genetics, 232(4). https://doi.org/10.1093/genetics/iyaf215

Mabruk, Z., Bullock, E., Xiao, X., Guo, J., Zhu, X., Gómez-Cuadrado, L., Oxvig, C., Mallon, E., Ammar, A., Malty, A., Pennel, K., Edwards, J. & Brunton, V. G. (2026). High Expression of PAPP-A Predicts Poor Outcomes in Oestrogen Receptor-Positive Breast Cancer Patients. Cancer Medicine, 15(4), e71815. https://doi.org/10.1002/cam4.71815

Hopkinson, A. T., Wilson, A. M., Pitfield, J., Muiña, A. T., Rácz, R., Mifsud, D. V., Herczku, P., Lakatos, G., Sulik, B., Juhász, Z., Biri, S., McCullough, R. W., Mason, N. J., Scavenius, C., Hornekær, L. & Ioppolo, S. (2026). An interstellar energetic and non-aqueous pathway to peptide formation. Nature Astronomy, 10(4), 531-539. https://doi.org/10.1038/s41550-025-02765-7

Rast, J. E., Rosso, A. L., James, B. D., Underwood, J. F. G., Bergstedt, J., Ahlqvist, V. H., Grove, J., Fang, F., Goldstein, N. D., Vivanti, G., Levine, S. Z., Nordström, A., Schendel, D., Lyall, K., Nordström, P., Ballin, M., Stafford, J., Naj, A. C., Lee, B. K. & LEGENNDS Consortium (2026). Association of neurodevelopmental conditions with Alzheimer's disease and related dementias and Parkinson's disease. The Journals of Gerontology. Series A: Biological Sciences & Medical Sciences, 81(4), Article glaf281. https://doi.org/10.1093/gerona/glaf281