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Latest peer-reviewed publications at MBG

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Astono, J., Jørgensen, A. G., Bus, C., Nielsen, S. D. H., Kjems, J. & Sundekilde, U. K. (2026). Global protein profiling of human milk using pre-enriched RNA-sequence libraries. Scientific Reports, 16(1), Article 11827. https://doi.org/10.1038/s41598-026-41374-w

Gordon, M., Akyol, T. Y., Amos, B., Andersen, S. U. & Williams, C. (2026). KeySDL: sparse dictionary learning for keystone microbe identification from steady-state observations using a dynamical-systems model. BioData Mining, 19(1), 18. Article 18. https://doi.org/10.1186/s13040-026-00527-3

Aagaard, J. B., Gandini, R., Ballegaard, A.-S. R., Krogstrup Jensen, B., Dorn, B., Verner, A., Lenstrup, A., Sønderholm, M., Miehe, M., Pfützner, W., Jakob, T., Andersen, G. R., Möbs, C. & Spillner, E. (2026). Nanobody-based IgG simultaneously inhibit the allergenic and enzymatic activity of the dominant honeybee venom allergen. Nature Communications, 17(1), Article 1814. https://doi.org/10.1038/s41467-026-69572-0

Bicer, D., Matsuoka, R., Moumbock, A. F. A., Sukumar, P., Suades, A., Cheruvara, H., Quigley, A., Drew, D., Pardon, E., Steyaert, J., Henderson, P. J. F., Caffrey, M., Griese, J. J. & Nji, E. (2026). Structural basis of specific lysine transport by Pseudomonas aeruginosa permease LysP. Nature Communications, 17(1), Article 37. https://doi.org/10.1038/s41467-025-66618-7

Pečnerová, P., Ishida, Y., Garcia-Erill, G., Bertola, L. D., Santander, C. G., Liu, X., Brüniche-Olsen, A., Khan, A., Hennelly, L. M., Balboa, R. F., Lin, L., Rasmussen, M. S., Wang, X., Schubert, M., Al-Chaer, A., Urbaniak, S., Nobuta, K., Treadup, S., Viaud-Martinez, K. A. ... Roca, A. L. (2026). The genomic impact of population connectivity and decline in Africa’s elephants. Nature Communications, 17(1), Article 3223. https://doi.org/10.1038/s41467-026-71262-w

Şen, A., Karaman, E., Heegaard, C. W., Poulsen, N. A. & Buitenhuis, A. J. (2026). Predicting riboflavin (vitamin B₂) and cobalamin (vitamin B₁₂) concentrations in Danish cow milk using Fourier transform mid infrared spectra. International Dairy Journal, 179, Article 106656. https://doi.org/10.1016/j.idairyj.2026.106656

Lopez-Aguileta, L., Martín-Encinas, E., Knudsen, B. R., Tesauro, C., Schirizzi, A., Montanaro, R., D'Alessandro, R., Perrone, M. G., Stefanachi, A., Contino, M. & Alonso, C. (2026). Synthesis and biological evaluation of novel fused pyridopyrimidine derivatives as topoisomerase I inhibitors and as potential antitumor agents: promising results in lung, ovary and gastric cancer. European Journal of Medicinal Chemistry, 310, Article 118782. https://doi.org/10.1016/j.ejmech.2026.118782

Kristjánsdóttir, N., Thorsen, K., Birkbak, N. J. & Dyrskjøt, L. (2026). Immune profiling of T cells: A comparative analysis of single-cell TCR sequencing using 10X Genomics and Parse Biosciences platforms. Biochemistry and Biophysics Reports, 46, Article 102592. https://doi.org/10.1016/j.bbrep.2026.102592

Demaegd, K. C., Kool, L., Baindoor, S., Donovan, P. D., Su, J., Westeneng, H. J., van Eijk, R. P. A., Geoghegan, G., Perez Morrissey, E., Halang, L., Poesen, K., Masrori, P., Gibriel, H. A. Y., Jirström, E., Venø, M. T., Kjems, J., Hardiman, O., Veldink, J. H., Kenna, K. ... van Es, M. A. (2026). Small RNA sequencing identifies serum tDR-1:34-Gly-GCC tiRNA levels as a biomarker for survival in amyotrophic lateral sclerosis. iScience, 29(5), Article 115636. https://doi.org/10.1016/j.isci.2026.115636

Walpole, S., Santiago-Vela, M. I., Birkedal, U., Hong, Z., Ros, X. B. D., van Overeem Hansen, T. & Wadt, K. A. W. (2026). Functional Analysis and Clinical Data Reclassify the DICER1 c.4206+1G>C Variant, Leading to Exon 22 Skipping, as Likely Pathogenic. Clinical Genetics, 109(5), 931-936. https://doi.org/10.1111/cge.70110

De Dios Andres, P., Garg, A., Alam, R., Westensee, I. N., Kjaergaard, M. & Städler, B. (2026). Transmembrane Condensation in Albumin-Loaded Giant Vesicles Induced by an Intrinsically Disordered Protein. ChemSystemsChem, 8(3), Article e00076. https://doi.org/10.1002/syst.202500076

Bernatz, S., Prudente, V., Pai, S., Attermann, A. K., Di Federico, A., Rowan, A., Veeriah, S., Dyrskjøt, L., Nürnberg, L., Alessi, J. V., Ott, P. A., Sharon, E., Hackshaw, A., McGranahan, N., Abbosh, C., Mak, R. H., Bitterman, D., Awad, M., Ricciuti, B. ... Aerts, H. J. W. L. (2026). Thymic health and immunotherapy outcomes in patients with cancer. Nature, 652(8111), 995-1003. https://doi.org/10.1038/s41586-026-10243-x

Bernatz, S., Prudente, V., Pai, S., Attermann, A. K., Cao, Y., Chen, J., Lyass, A., Foldyna, B., Nürnberg, L., Bressem, K., Abbosh, C., Swanton, C., Jamal-Hanjani, M., Lu, M. T., Murabito, J. M., Lunetta, K. L., Birkbak, N. J. & Aerts, H. J. W. L. (2026). Thymic health consequences in adults. Nature, 652(8111), 986-994. https://doi.org/10.1038/s41586-026-10242-y

Vinther, S. C., Resag, A., Le, K. T. T., Zelle-Rieser, C. C., Strandt, H., Malle, M. G., Christiansen, S. H., Del Frari, B., Stigger, T., Schilling, B., Wohlfarth, J., Thiel, S., Valero, J., Stoitzner, P. & Kjems, J. (2026). Targeting Langerhans cells using a modular mannosylated nucleic acid-based vaccine platform. Journal of Controlled Release, 392, 114741. Article 114741. https://doi.org/10.1016/j.jconrel.2026.114741

Vasilevsky, N. A., Toro, S., Matentzoglu, N., Flack, J. E., Mullen, K. R., Hegde, H., Gehrke, S., Whetzel, P. L., Shwetar, Y., Harris, N. L., Ngu, M. S., Alyea, G. L., Kane, M. S., Roncaglia, P., Sid, E., Thaxton, C. L., Wood, V., Abraham, R. S., Achatz, M. I. ... Haendel, M. A. (2026). Mondo: integrating disease terminology across communities. Genetics, 232(4). https://doi.org/10.1093/genetics/iyaf215

Andersen, L., Lindskrog, S. V., Nordentoft, I., Frydendahl, A., Nors, J., Henriksen, T. V., Rasmussen, M. H., Iversen, L. H., Gotschalck, K. A., Jensen, J. B., Dyrskjøt, L., Andersen, C. L. & Birkbak, N. J. (2026). Cell-Free DNA-Derived Immune Cell Ratios Uncover Cancer-Associated Systemic Changes. Cancer Research Communications, 6(4), 811-820. https://doi.org/10.1158/2767-9764.CRC-25-0747

Mabruk, Z., Bullock, E., Xiao, X., Guo, J., Zhu, X., Gómez-Cuadrado, L., Oxvig, C., Mallon, E., Ammar, A., Malty, A., Pennel, K., Edwards, J. & Brunton, V. G. (2026). High Expression of PAPP-A Predicts Poor Outcomes in Oestrogen Receptor-Positive Breast Cancer Patients. Cancer Medicine, 15(4), e71815. https://doi.org/10.1002/cam4.71815

Hopkinson, A. T., Wilson, A. M., Pitfield, J., Muiña, A. T., Rácz, R., Mifsud, D. V., Herczku, P., Lakatos, G., Sulik, B., Juhász, Z., Biri, S., McCullough, R. W., Mason, N. J., Scavenius, C., Hornekær, L. & Ioppolo, S. (2026). An interstellar energetic and non-aqueous pathway to peptide formation. Nature Astronomy, 10(4), 531-539. https://doi.org/10.1038/s41550-025-02765-7

Lildballe, D. L., Huno, M. R., Ridder, L. O. R., Balle, C. M., Drue, S. O., Berglund, A., Dunø, M., Bak, E. N., Viuff, M. H., Rasmussen, L. S. & Gravholt, C. H. (2026). Genetic diagnosis of CYP21A2-related CAH: adaptive sampling long-read sequencing is an accurate and scalable solution. European Journal of Human Genetics, 34(4), 535-542. https://doi.org/10.1038/s41431-026-02019-8

Rattan, S. (2026). Lifespan stops at death, but when does healthspan stop? Biogerontology, 27(2), 78. Article 78. https://doi.org/10.1007/s10522-026-10424-1

Czyżewski, S., Søndergaard, S. A., Molnár, Á. P., Kerr, M. R., Kristensen, J. A., Atkinson, J., Trepel, J., Sykut, M., Radzikowski, P., Termansen, S. S., Wałach, K., Pearce, E. A., Pang, S. E. H., Zając, B., Bergman, J., Thomassen, E. S., Mungi, N., Fløjgaard, C., Ejrnæs, R. ... Svenning, J. C. (2026). Revisiting Europe's temperate forests: Palaeoecological evidence for an herbivory-driven woodland-grassland mosaic biome. Biological Conservation, 316, Article 111749. https://doi.org/10.1016/j.biocon.2026.111749

Kats, P., Zhou, X., Wiebe, J., Zeymer, O., Baruch, P., Taft, M. H., Reinke, P. Y. A., Günther, S., Meents, A., Hartmann, R., Manstein, D. J. & Fedorov, R. (2026). The Enzymatic Mechanism of OAS: How Metal Ions and Quantum Effects Help Activate Innate Immunity. ACS Omega, 11(16), 24250-24268. https://doi.org/10.1021/acsomega.5c13236

Djavani-Tabrizi, I., Lindkvist, T. T., Otzen, D. E. & Nielsen, S. B. (2026). When motion slows: intrinsic photophysics of thioflavin T and X cations at cryogenic temperatures. Physical Chemistry Chemical Physics. Advance online publication. https://doi.org/10.1039/d6cp00731g

Neis, K., Civit Pitarch, L., Pedersen, K., Schachtner, M., Wengel, J., Wagner, R., Thiel, S., Kjems, J. & Valero Moreno, J. (2026). Lock, Protect, and Bind: In Vitro Selection of Locked Nucleic Acid-Modified Aptamers Using a Mutant T7 RNA Polymerase. Small Structures, 7(3), Article e202500677. https://doi.org/10.1002/sstr.202500677

Gázquez-Gutiérrez, A., Chin, P., Peris, G., Gordon, K., Marchante, P. G., Witteveldt, J., Tristán-Ramos, P., Rouvière, J. O., Knol, L. I., Ivens, A., López-Onieva, L., Estévez, A. M., Garland, W., Jensen, T. H., Heras, S. R. & Macias, S. (2026). Control of retrotransposon-driven activation of the interferon response by the double-stranded RNA binding protein DGCR8. Nucleic Acids Research, 54(5), Article gkag190. https://doi.org/10.1093/nar/gkag190

Møhlenberg, M., Jørgensen, S. E., Marije van der Sluis, R., Zillinger, T., Hinke, D. M., Hollensen, A. K., Hansen, A. L., Hausfater, P., Gorochov, G., Tubach, F., Ghosn, J., Laouenan, C., Storgaard, M., Holm, C. K., Su, H., Pérez de Diego, R., Pujol, A., Zhang, S.-Y., Zhang, Q. ... COVID Human Genetic Effort (2026). Defective RNA Polymerase III sensing of mitochondrial DNA in pulmonary epithelial cells impairs type I IFN immunity to SARS-CoV-2. Proceedings of the National Academy of Sciences of the United States of America, 123(12), Article e2522111123. https://doi.org/10.1073/pnas.2522111123

Mishra, A., Zubia-Aranburu, J., Zuzic, L., Saeed, K., Nielsen, J., Schio̷tt, B., Dong, M., Otzen, D. E. & Weidner, T. (2026). Structure of α-Synuclein Bound to Polystyrene Surfaces Probed by Experimental and Theoretical Sum Frequency Generation Spectroscopy. Langmuir : the ACS journal of surfaces and colloids, 42(11), 7653-7659. https://doi.org/10.1021/acs.langmuir.5c05658

Zhang, X., Hitt, P., Wanunu, M. & Kjems, J. (2026). Scalable Production of DNA-Probe-Functionalized Heteromeric MspA Nanopores for Biosensing. ACS Applied Materials and Interfaces, 18(10), 14531-14539. https://doi.org/10.1021/acsami.5c21011

Fischer, C. M., Edu, I. A., Šneideris, T., Baronaite, I., Toprakcioglu, Z., Deck, L.-T., Qian, D., Scrutton, R., Dreyer, L., Wen, J., Otzen, D. E., Wu, S., Perrett, S. & Knowles, T. P. J. (2026). Reversibility and β-sheet formation are decoupled in tau condensate aging. Proceedings of the National Academy of Sciences of the United States of America, 123(11), Article e2522993123. https://doi.org/10.1073/pnas.2522993123

Riedelbauch, S., Masser, S., Fasching, S., Lin, S. Y., Salgania, H. K., Aarup, M., Ebert, A., Jeske, M., Levine, M. T., Stelzl, U. & Andersen, P. (2026). Recurrent innovation of protein-protein interactions in the Drosophila piRNA pathway. EMBO Journal, 45(6), 1909-1932. Article 98. https://doi.org/10.1038/s44318-025-00439-8

Rodriguez, A., Formoso, E., Knudsen, B. R., Tesauro, C., Fuertes, M. & Alonso, C. (2026). Synthesis, Biological Evaluation, and Theoretical Study of Indenoquinolinylphosphine Oxide Derivatives as Topoisomerase 1 Inhibitors and Antiproliferative Agents. ChemMedChem, 21(5), Article e202500751. https://doi.org/10.1002/cmdc.202500751

Song, P., Su, J., Kristine Vraa, C. L., Gockert, M., Fjelstrup, S., Hager, H. & Kjems, J. (2026). Optimizing C14120-based LNPs for in vitro and in vivo mRNA delivery. Molecular Therapy Nucleic Acids, 37(1), Article 102866. https://doi.org/10.1016/j.omtn.2026.102866

Rast, J. E., Rosso, A. L., James, B. D., Underwood, J. F. G., Bergstedt, J., Ahlqvist, V. H., Grove, J., Fang, F., Goldstein, N. D., Vivanti, G., Levine, S. Z., Nordström, A., Schendel, D., Lyall, K., Nordström, P., Ballin, M., Stafford, J., Naj, A. C., Lee, B. K. & LEGENNDS Consortium (2026). Association of neurodevelopmental conditions with Alzheimer's disease and related dementias and Parkinson's disease. The Journals of Gerontology. Series A: Biological Sciences & Medical Sciences, 81(4), Article glaf281. https://doi.org/10.1093/gerona/glaf281

Juhl, A. D., Sprenger, R. R., Modzel, M., Halder, S., Szomek, M., Akkerman, V., Xu, Y., Heegaard, C. W., Ejsing, C. S., Covey, D. F. & Wüstner, D. (2026). Live-Cell Imaging and Lipidomics of Low-Density Lipoprotein Containing Intrinsically Fluorescent Cholesteryl Esters. Analytical Chemistry, 98(9), 7069-7083. https://doi.org/10.1021/acs.analchem.5c05064

Tedeschi, F., Quilbé, J., Fechete, L. I., Vistisen Christiansen, S. J. & Andersen, S. U. (2026). RHD6LA regulates root hair responses to both symbionts and commensals. Nature Communications. Advance online publication. https://doi.org/10.1038/s41467-026-70504-1

Clark, EL., Amaral, A., Baranasic, D., Barta, E., Cartick, G., Chua, P., Espinosa-Carrasco, J., Fang, L., Fischer, D., Foissac, S., Gillard, G., Giuffra, E., Hartwig, T., Heil, KF., Henkel, C., Kadarmideen, HN., Klingström, T., MacHugh, DE., Murdoch, BM. ... Larzul, C. (2026). Establishing the ELIXIR Domestic Animals Genome and Phenome Community. F1000Research, 15(339), Article 339. https://doi.org/10.12688/f1000research.177500.1, https://doi.org/10.12688/f1000research.177500.1

Zhang, H., Windhorst, A., Bornhofen, E., Tulpova, Z., Novak, P., Macas, J., Simkova, H., Nadzieja, M., Kim, J. M., Cram, D., Cao, Y., Konkin, D. J. F., Sass, O., Welna, G., Himmelbach, A., Mascher, M., Link, W., Kwon, S.-J., Yang, T.-J. ... Jayakodi, M. (2026). Allelic variation at a single locus distinguishes spring and winter faba beans. Nature Genetics, 58(3), 655-663. https://doi.org/10.1038/s41588-026-02524-y