The zebrafish offers unique possibilities for in vivo analyses in a vertebrate organism. 71.4 percent of human genes have zebrafish orthologs, powerful genetic tools are available, and the use of zebrafish for modeling human disease is well established. Because fertilization and embryonic development is external and the embryo is optically transparent, non-invasive in vivo observation and imaging at cellular and subcellular resolution is possible. Imaging is further facilitated by the use of transgenic zebrafish lines expressing fluorescent reporters.
The zebrafish is widely used in numerous fields including but not limited to biomedical research, developmental biology, drug discovery, and toxicology.
The zebrafish facility houses several wild-type zebrafish strains and multiple mutant and transgenic lines.
Questions or queries about potential projects using zebrafish should be directed to Kasper Kjær-Sørensen or Claus Oxvig.
