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Department of Molecular Biology and Genetics

Publications

Peter Andersen - Laboratory on Genetic Innovation

Key recent publications (pre-2020)

A Heterochromatin-Specific RNA Export Pathway Facilitates piRNA Production
ElMaghraby, M. F.†, Andersen, P. R.†#, Pühringer, F., Hohmann, U., Meixner, K., Lendl, T., Tirian, L. & Brennecke, J.† Cell 178, 4, p. 964-979.e20 (2019)

A heterochromatin-dependent transcription machinery drives piRNA expression.
Andersen, P. R.#, Tirian, L., Vunjak, M. & Brennecke, J.# Nature 549, 54–59 (2017).
Highlighted by: Zamore, P. D. Molecular biology: Rhino gives voice to silent chromatin. Nature 549, 38–39 (2017).
Highlighted by: Burgess, D. J. Chromatin: Probing a piRNA paradox. Nat Rev Genet 18, 638–639 (2017).

† Equal contribution # shared corresponding author

Preprint publications

A heterochromatin-specific RNA export pathway facilitates piRNA production.
ElMaghraby M. F. †, Andersen P. R.# †, Pühringer F., Meixner K., Lendl T., Tirian T. & Brennecke J.# BioRxiv, doi.org/10.1101/596171 (2019)

Peer-reviewed publications

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ElMaghraby, M. F., Andersen, P. R., Pühringer, F., Hohmann, U., Meixner, K., Lendl, T., Tirian, L. & Brennecke, J. (2019). A Heterochromatin-Specific RNA Export Pathway Facilitates piRNA Production. Cell, 178(4), 964-979. https://doi.org/10.1016/j.cell.2019.07.007

Andersen, P. R., Tirian, L., Vunjak, M. & Brennecke, J. (2017). A heterochromatin-dependent transcription machinery drives piRNA expression. Nature, 549(7670), 54-59. https://doi.org/10.1038/nature23482

Lubas, M. S., Andersen, P. R., Schein, A., Dziembowski, A., Kudla, G. & Jensen, T. H. (2015). The Human Nuclear Exosome Targeting Complex Is Loaded onto Newly Synthesized RNA to Direct Early Ribonucleolysis. Cell Reports, 10(2), 178-183. https://doi.org/10.1016/j.celrep.2014.12.026

Andersson, R., Gebhard, C., Miguel-Escalada, I., Hoof, I., Bornholdt, J., Boyd, M., Chen, Y., Zhao, X., Schmidl, C., Suzuki, T., Ntini, E., Arner, E., Valen, E., Li, K., Schwarzfischer, L., Glatz, D., Raithel, J., Lilje, B., Rapin, N. ... FANTOM Consortium (2014). An atlas of active enhancers across human cell types and tissues. Nature, 507, 455-461. https://doi.org/10.1038/nature12787

Hallais, M., Pontvianne, F., Andersen, P. R., Clerici, M., Lener, D., Benbahouche, N. E. H., Gostan, T., Vandermoere, F., Robert, M-C., Cusack, S., Verheggen, C., Jensen, T. H. & Bertrand, E. (2013). CBC-ARS2 stimulates 3'-end maturation of multiple RNA families and favors cap-proximal processing. Nature Structural and Molecular Biology, 20(12), 1358-1366. https://doi.org/10.1038/nsmb.2720

Ntini, E., Järvelin, A. I., Bornholdt, J., Chen, Y., Boyd, M., Jørgensen, M., Andersson, R., Hoof, I., Schein, A., Andersen, P. R., Andersen, P. K., Preker, P., Valen, E., Zhao, X., Pelechano, V., Steinmetz, L. M., Sandelin, A. G. & Jensen, T. H. (2013). Polyadenylation site-induced decay of upstream transcripts enforces promoter directionality. Nature Structural and Molecular Biology, 20(8), 923-928. https://doi.org/10.1038/nsmb.2640

Andersen, P. R., Domanski, M., Kristiansen, M. S., Storvall, H., Ntini, E., Verheggen, C., Schein, A., Bunkenborg, J., Poser, I., Hallais, M., Sandberg, R., Hyman, A., Lacava, J., Rout, M. P., Andersen, J. S., Bertrand, E. & Jensen, T. H. (2013). The human cap-binding complex is functionally connected to the nuclear RNA exosome. Nature Structural and Molecular Biology, 20(12), 1367-1376. https://doi.org/10.1038/nsmb.2703

Valen, E., Preker, P., Andersen, P. R., Zhao, X., Chen, Y., Ender, C., Dueck, A., Meister, G., Sandelin, A. G. & Jensen, T. H. (2011). Biogenic mechanisms and utilization of small RNAs derived from human protein-coding genes. Nature Structural and Molecular Biology, 18(9), 1075-82. https://doi.org/10.1038/nsmb.2091

Moldt, B., Yant, S. R., Andersen, P. R., Kay, M. A. & Mikkelsen, J. G. (2007). Cis-acting gene regulatory activities in the terminal regions of sleeping beauty DNA transposon-based vectors. Human Gene Therapy, 18(12), 1193-204. https://doi.org/10.1089/hum.2007.099

All publications by Pubmed search: Peter Refsing Andersen OR Peter Ebert Andersen

Revised 18.01.2022 -

Lisbeth Heilesen