During her PhD studies, Astrid Pold Vilstrup researched gene expression in the germline of fruit fly males.
The germline tissue is special in that it forms the gametes ensuring that genetic material is transferred to the
next generation. Astrid Pold Vilstrup studied how male fertility and processing of genes expressed in the
male germline are dependent on an, until now, uncharacterized protein complex that have emerged by gene
duplications.

The new research findings contribute to our understanding of how germline-specific gene expression and
fertility is dependent on duplications of core biological machineries.

The PhD study was completed at the Department of Molecular Biology and Genetics, Faculty of Natural
Sciences, Aarhus University.

This summary was prepared by the PhD student.

Time: Thursday, 22 June 2023 at 1 PM
Place: Building 1872, room 647, Department of Molecular Biology and Genetics, Aarhus University,
Universitetsbyen 81, 8000 Aarhus C
Title of PhD thesis: Paralog-based genome regulation in the male germline of Drosophila melanogaster

Contact information: Astrid Pold Vilstup, e-mail: apvil@mbg.au.dk, tel.: +45 40403061

Members of the assessment committee:
Associate Professor Kristian Almstrup, Department of Growth and Reproduction, Copenhagen University Hospital and University of Copenhagen, Denmark

Group Leader Joan Barau, Institute of Molecular Biology gGmbH Mainz, Germany

Associate Professor Pia Møller Martensen (chair), Department of Molecular Biology and Genetics, Aarhus University, Denmark

Main supervisor:
Associate Professor Christian Kroun Damgaard, Department of Molecular Biology and Genetics, Aarhus University, Denmark

Co-supervisor:
Assistant Professor Peter Ebert Andersen, Department of Molecular Biology and Genetics, Aarhus University, Denmark

Language: The PhD dissertation will be defended in English
The defence is public.
The PhD thesis is available for reading at the Graduate School of Natural Sciences/GSNS,
Jens Baggesens Vej 53, building 5221, 8200 Aarhus N.