During her PhD studies, Klara Theresa Scholtissek researched proteins that transport lipids over the cellular membrane. The cellular membrane is built up by a bilayer of lipids which cannot move to the other leaflet without help of lipid transporters. Klara Theresa Scholtissek studied how one of the proteins, the so-called lipid flippases, selectively binds one type of lipid over the others, transports it and also how the protein is activated.

The new research findings contribute to the understanding of how lipids are transported over the membrane and more specifically how they are recognized and transported by these proteins.

The PhD study was completed at the Department of Molecular Biology and Genetics, Faculty of Natural Sciences, Aarhus University.

This summary was prepared by the PhD student.

Time: Friday, 01 November 2024 at 13:00
Place: Building 1253, room 211, Lecture Theatre Merete Barker Auditorium, MBG, Aarhus University, Bartholins Allé 3, 8000 Århus
Title of PhD thesis: About structural and functional studies of the human lipid flippase family ATP10s
Contact information: Klara Theresa Scholtissek, e-mail: klsc@mbg.au.dk, tel.: +45 36605190

Members of the assessment committee:
Professor Anja Thoe Fuglsang, Department of Plant and Environmental Sciences, University of Copenhagen, Denmark

Dr. rer. nat. Maike Bublitz-Meier, Institut für Translationale Medizin, Private Universität im Fürstentum, Liechtenstein

Associate Professor Christian Kroun Damgaard (chair), Department of Molecular Biology and Genetics, Aarhus University, Denmark

Main supervisor:
Professor Bjørn Panyella Pedersen, Department of Molecular Biology and Genetics, Aarhus University, Denmark

Co-supervisor:

Assistance Professor Joseph Lyons, iNANO, Aarhus University, Denmark

Language: The PhD dissertation will be defended in English

The defence is public.
The PhD thesis is available for reading at the Graduate School of Natural Sciences/GSNS, Ny Munkegade 120, building 1521, 8000 Aarhus C