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Latest peer-reviewed publications at MBG

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Displaying results 1101 to 63 out of 63

Peer-reviewed publications at MBG - all years

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Mendoza-Suárez, M., Andersen, S. U., Poole, P. S. & Sánchez-Cañizares, C. (2021). Competition, Nodule Occupancy, and Persistence of Inoculant Strains: Key Factors in the Rhizobium-Legume Symbioses. Frontiers in Plant Science, 12, Article 690567. https://doi.org/10.3389/fpls.2021.690567

Najarzadeh, Z., Nielsen, J., Farzadfard, A., Sereikaite, V., Strømgaard, K., Meyer, R. L. & Otzen, D. E. (2021). Human Fibrinogen Inhibits Amyloid Assembly of Most Phenol-Soluble Modulins from Staphylococcus aureus. ACS Omega, 6(34), 21960-21970. https://doi.org/10.1021/acsomega.1c02333

Selas, A., Fuertes, M., Melcón-Fernández, E., Pérez-Pertejo, Y., Reguera, R. M., Balaña-Fouce, R., Knudsen, B. R., Palacios, F. & Alonso, C. (2021). Hybrid quinolinyl phosphonates as heterocyclic carboxylate isosteres: Synthesis and biological evaluation against topoisomerase 1B (TOP1B). Pharmaceuticals, 14(8), Article 784. https://doi.org/10.3390/ph14080784

Julienne, H., Laville, V., McCaw, Z. R., He, Z., Guillemot, V., Lasry, C., Ziyatdinov, A., Nerin, C., Vaysse, A., Lechat, P., Ménager, H., Le Goff, W., Dube, M.-P., Kraft, P., Ionita-Laza, I., Vilhjálmsson, B. J. & Aschard, H. (2021). Multitrait GWAS to connect disease variants and biological mechanisms. PLoS Genetics, 17(8), Article e1009713. https://doi.org/10.1371/journal.pgen.1009713

Taschner, M., Basquin, J., Steigenberger, B., Schäfer, I. B., Soh, Y. M., Basquin, C., Lorentzen, E., Räschle, M., Scheltema, R. A. & Gruber, S. (2021). Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding. EMBO Journal, 40(15), Article e107807. https://doi.org/10.15252/embj.2021107807

Strom, N. I., Grove, J., Meier, S. M., Bækvad-Hansen, M., Becker Nissen, J., Damm Als, T., Halvorsen, M., Nordentoft, M., Mortensen, P. B., Hougaard, D. M., Werge, T., Mors, O., Børglum, A. D., Crowley, J. J., Bybjerg-Grauholm, J. & Mattheisen, M. (2021). Polygenic Heterogeneity Across Obsessive-Compulsive Disorder Subgroups Defined by a Comorbid Diagnosis. Frontiers in Genetics, 12, Article 711624. https://doi.org/10.3389/fgene.2021.711624

Winters, J., Kobek-Kjeldager, C., Foldager, L. & Pedersen, L. J. (2021). Preliminary results on the effect of keeping pigs in home environment post weaning. In E. Strandberg, L. Pinotti, S. Messori, D. Kenny, M. Lee, J. F. Hocquette, V. A. P. Cadavez, S. Millet, R. Evans, T. Veldkamp, M. Pastell & G. Pollott (Eds.), Book of Abstracts of the 72nd Annual Meeting of the European Federation of Animal Science (pp. 356-356). Wageningen Academic Publishers. https://doi.org/10.3920/978-90-8686-918-3

Christensen, M., Petersen, J. L., Sivanandam, P., Kronborg, C. S., Knudsen, U. B. & Martensen, P. M. (2021). Reduction of serum-induced endothelial STAT3(Y705) activation is associated with preeclampsia. Pregnancy Hypertension, 25, 103-109. https://doi.org/10.1016/j.preghy.2021.05.012

Vandestadt, C., Vanwalleghem, G. C., Khabooshan, M. A., Douek, A. M., Castillo, H. A., Li, M., Schulze, K., Don, E., Stamatis, S. A., Ratnadiwakara, M., Änkö, M. L., Scott, E. K. & Kaslin, J. (2021). RNA-induced inflammation and migration of precursor neurons initiates neuronal circuit regeneration in zebrafish. Developmental Cell, 56(16), 2364-2380.e8. https://doi.org/10.1016/j.devcel.2021.07.021

Shemesh, M., Aktepe, T. E., Deerain, J. M., McAuley, J. L., Audsley, M. D., David, C. T., Purcell, D. F. J., Urin, V., Hartmann, R., Moseley, G. W., Mackenzie, J. M., Schreiber, G. & Harari, D. (2021). SARS-CoV-2 suppresses IFNβ production mediated by NSP1, 5, 6, 15, ORF6 and ORF7b but does not suppress the effects of added interferon. PLoS Pathogens, 17(8), Article e1009800. https://doi.org/10.1371/journal.ppat.1009800

Petersen, K. V., Selas, A., Hymøller, K. M., Mizielinski, K., Thorsager, M., Stougaard, M., Alonso, C., Palacios, F., Pérez-Pertejo, Y., Reguera, R. M., Balaña-Fouce, R., Knudsen, B. R. & Tesauro, C. (2021). Simple and fast DNA based sensor system for screening of small-molecule compounds targeting eukaryotic topoisomerase 1. Pharmaceutics, 13(8), Article 1255. https://doi.org/10.3390/pharmaceutics13081255

Zhang, N., Kisiswa, L., Ramanujan, A., Li, Z., Sim, E. W., Tian, X., Yuan, W., Ibáñez, C. F. & Lin, Z. (2021). Structural basis of NF-κB signaling by the p75 neurotrophin receptor interaction with adaptor protein TRADD through their respective death domains. Journal of Biological Chemistry, 297(2), Article 100916. https://doi.org/10.1016/j.jbc.2021.100916

Timcenko, M., Dieudonné, T., Montigny, C., Boesen, T., Lyons, J. A., Lenoir, G. & Nissen, P. (2021). Structural Basis of Substrate-Independent Phosphorylation in a P4-ATPase Lipid Flippase. Journal of Molecular Biology, 433(16), Article 167062. https://doi.org/10.1016/j.jmb.2021.167062

Hansen, S. B., Dyla, M., Neumann, C., Quistgaard, E. M. H., Andersen, J. L., Kjaergaard, M. & Nissen, P. (2021). The Crystal Structure of the Ca²⁺-ATPase 1 from Listeria monocytogenes reveals a Pump Primed for Dephosphorylation. Journal of Molecular Biology, 433(16), Article 167015. https://doi.org/10.1016/j.jmb.2021.167015

Rogato, A., Valkov, V. T., Nadzieja, M., Stougaard, J. & Chiurazzi, M. (2021). The lotus japonicus AFB6 gene is involved in the auxin dependent root developmental program. International Journal of Molecular Sciences , 22(16), Article 8495. https://doi.org/10.3390/ijms22168495

Krönauer, C. & Radutoiu, S. (2021). Understanding Nod factor signalling paves the way for targeted engineering in legumes and non-legumes. Current Opinion in Plant Biology, 62, Article 102026. https://doi.org/10.1016/j.pbi.2021.102026

Lee, Y.-L., Takeda, H., Moreira, G. C. M., Karim, L., Mullaart, E., Coppieters, W., GplusE Consortium, Appeltant, R., Veerkamp, R. F., Groenen, M. A. M., Georges, M., Bosse, M., Druet, T., Bouwman, A. C. & Charlier, C. (2021). A 12 kb multi-allelic copy number variation encompassing a GC gene enhancer is associated with mastitis resistance in dairy cattle. PLoS Genetics, 17(7), Article e1009331. https://doi.org/10.1371/journal.pgen.1009331

Jakobsen, A.-K., Keller-Socin, J. G., Gonzales, M., Martín-Encinas, E., Palacios, F., Alonso, C., Knudsen, B. R. & Stougaard, M. (2021). A Dual-Sensor-Based Screening System for In Vitro Selection of TDP1 Inhibitors. Sensors, 21(14), Article 4832. https://doi.org/10.3390/s21144832

Fernandez-Cantos, M. V., Garcia-Morena, D., Iannone, V., El-Nezami, H., Kolehmainen, M. & Kuipers, O. P. (2021). Role of microbiota and related metabolites in gastrointestinal tract barrier function in NAFLD. Tissue barriers, 9(3), 1879719. Article 1879719. https://doi.org/10.1080/21688370.2021.1879719

Dubey, V., Stokes, D. L., Pedersen, B. P. & Khandelia, H. (2021). An Intracellular Pathway Controlled by the N-terminus of the Pump Subunit Inhibits the Bacterial KdpFABC Ion Pump in High K⁺ Conditions. Journal of Molecular Biology, 433(15), Article 167008. https://doi.org/10.1016/j.jmb.2021.167008

Christensen, K. J., Dreier, J. W., Skotte, L., Feenstra, B., Grove, J., Børglum, A., Mitrovic, M., Cotsapas, C. & Christensen, J. (2021). Birth characteristics and risk of febrile seizures. Acta Neurologica Scandinavica, 144(1), 51-57. https://doi.org/10.1111/ane.13420

Harwood, S. L., Nielsen, N. S., Diep, K., Jensen, K. T., Nielsen, P. K., Yamamoto, K. & Enghild, J. J. (2021). Development of selective protease inhibitors via engineering of the bait region of human α2-macroglobulin. The Journal of Biological Chemistry, 297(1), Article 100879. https://doi.org/10.1016/j.jbc.2021.100879

Thomsen, A. H., Leth, P. M., Hougen, H. P. & Villesen, P. (2021). Gunshot homicides in Denmark 1992-2016. International Journal of Legal Medicine (Online), 135(4), 1507-1514. https://doi.org/10.1007/s00414-021-02548-5

Ferreira, N., Gram, H., Sorrentino, Z. A., Gregersen, E., Schmidt, S. I., Reimer, L., Betzer, C., Perez-Gozalbo, C., Beltoja, M., Nagaraj, M., Wang, J., Nowak, J. S., Dong, M., Willén, K., Cholak, E., Bjerregaard-Andersen, K., Mendez, N., Rabadia, P., Shahnawaz, M. ... Jensen, P. H. (2021). Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential. Acta Neuropathologica, 142, 87-115. https://doi.org/10.1007/s00401-021-02316-0

Nielsen, N. S., Gadeberg, T. A. F., Poulsen, E. T., Harwood, S. L., Weberskov, C. E., Pedersen, J. S., Andersen, G. R. & Enghild, J. J. (2021). Mutation-induced dimerization of transforming growth factor-β-induced protein may drive protein aggregation in granular corneal dystrophy. The Journal of Biological Chemistry, 297(1), Article 100858. https://doi.org/10.1016/j.jbc.2021.100858

Walther, R., Monge, P., Pedersen, A., Benderoth, A., Pedersen, J., Farzadfard, A., Mandrup, O., Howard, K., Otzen, D. & Zelikin, A. N. (2021). Per-glycosylation of the Surface-Accessible Lysines: One-Pot Aqueous Route to Stabilized Proteins with Native Activity. ChemBioChem, 22(14), 2478-2485. https://doi.org/10.1002/cbic.202100228

Monrad, I., Sahlertz, S. R., Nielsen, S. S. F., Pedersen, L. Ø., Petersen, M. S., Kobel, C. M., Tarpgaard, I. H., Storgaard, M., Mortensen, K. L., Schleimann, M. H., Tolstrup, M. & Vibholm, L. K. (2021). Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Immunocompromised Host Displaying Treatment Induced Viral Evolution. Open Forum Infectious Diseases, 8(7), Article ofab295. https://doi.org/10.1093/ofid/ofab295

Musliner, K. L., Agerbo, E., Vilhjálmsson, B. J., Albiñana, C., Als, T. D., Østergaard, S. D. & Mortensen, P. B. (2021). Polygenic Liability and Recurrence of Depression in Patients With First-Onset Depression Treated in Hospital-Based Settings. JAMA Psychiatry, 78(7), 792-795. https://doi.org/10.1001/jamapsychiatry.2021.0701

Sweet, M. E., Larsen, C., Zhang, X., Schlame, M., Pedersen, B. P. & Stokes, D. L. (2021). Structural basis for potassium transport in prokaryotes by KdpFABC. Proceedings of the National Academy of Sciences (PNAS), 118(29), Article e2105195118. https://doi.org/10.1073/pnas.2105195118

Kock Flygaard, R., Neumann, C., Anthony Lyons, J. & Nissen, P. (2021). Transport unplugged: KCCs are regulated through an N-terminal plug of the ion pathway. EMBO Journal, 40(14), Article e108371. https://doi.org/10.15252/embj.2021108371

Björnsdotter, E., Nadzieja, M., Chang, W., Escobar-Herrera, L., Mancinotti, D., Angra, D., Xia, X., Tacke, R., Khazaei, H., Crocoll, C., Vandenberg, A., Link, W., Stoddard, F. L., O'Sullivan, D. M., Stougaard, J., Schulman, A. H., Andersen, S. U. & Geu-Flores, F. (2021). VC1 catalyses a key step in the biosynthesis of vicine in faba bean. Nature Plants, 7(7), 923-931. https://doi.org/10.1038/s41477-021-00950-w

Gerdes, K., Bærentsen, R. & Brodersen, D. E. (2021). Phylogeny Reveals Novel HipA-Homologous Kinase Families and Toxin-Antitoxin Gene Organizations. mBio, 12(3), e0105821. Article e01058-21. https://doi.org/10.1128/mBio.01058-21

Del Amo-Maestro, L., Sagar, A., Pompach, P., Goulas, T., Scavenius, C., Ferrero, D. S., Castrillo-Briceño, M., Taulés, M., Enghild, J. J., Bernadó, P. & Gomis-Rüth, F. X. (2021). An Integrative Structural Biology Analysis of Von Willebrand Factor Binding and Processing by ADAMTS-13 in Solution. Journal of Molecular Biology, 433(13), Article 166954. https://doi.org/10.1016/j.jmb.2021.166954

Atashi, H., Hostens, M. & GplusE Consortium (2021). Genetic parameters for milk urea and its relationship with milk yield and compositions in Holstein dairy cows. PLoS One, 16(6), Article e0253191. https://doi.org/10.1371/journal.pone.0253191

Olivieri, D., Castelli, E., Kawamura, Y. K., Papasaikas, P., Lukonin, I., Rittirsch, M., Hess, D., Smallwood, S. A., Stadler, M. B., Peters, A. H. F. M. & Betschinger, J. (2021). Cooperation between HDAC3 and DAX1 mediates lineage restriction of embryonic stem cells. EMBO Journal, 40(12), e106818. Article e106818. https://doi.org/10.15252/embj.2020106818

Rasmussen, H. Ø., Otzen, D. E. & Pedersen, J. S. (2021). A multimethod approach for analyzing FapC fibrillation and determining mass per length. Biophysical Journal, 120(11), 2262-2275. https://doi.org/10.1016/j.bpj.2021.03.031

Christiansen, M. K., Winther, S., Nissen, L., Vilhjálmsson, B. J., Frost, L., Johansen, J. K., Loof Møller, P., Schmidt, S. E., Westra, J. S., Holm, N. R., Jensen, H. K., Christiansen, E. H., Guðbjartsson, D. F., Hólm, H., Stefansson, K., Bøtker, H. E., Bøttcher, M. & Nyegaard, M. (2021). Polygenic Risk Score-enhanced Risk Stratification of Coronary Artery Disease in Patients with Stable Chest Pain. Circulation: Genomic and Precision Medicine, 14(3), E003298. Article 003298. https://doi.org/10.1161/CIRCGEN.120.003298

Lykke-Andersen, S., Rouvière, J. O. & Jensen, T. H. (2021). ARS2/SRRT: At the nexus of RNA polymerase II transcription, transcript maturation and quality control. Biochemical Society Transactions, 49(3), 1325-1336. https://doi.org/10.1042/BST20201008

Jensen, R. K., Bajic, G., Sen, M., Springer, T. A., Vorup-Jensen, T. & Andersen, G. R. (2021). Complement receptor 3 forms a compact high-affinity complex with iC3b. Journal of Immunology, 206(12), 3032-3042. https://doi.org/10.4049/jimmunol.2001208

Yang, C., Zhou, Y., Marcus, S., Formenti, G., Bergeron, L. A., Song, Z., Bi, X., Bergman, J., Rousselle, M. M. C., Zhou, C., Zhou, L., Deng, Y., Fang, M., Xie, D., Zhu, Y., Tan, S., Mountcastle, J., Haase, B., Balacco, J. ... Zhang, G. (2021). Evolutionary and biomedical insights from a marmoset diploid genome assembly. Nature, 594(7862), 227-233. https://doi.org/10.1038/s41586-021-03535-x

Martin, J., Khramtsova, E. A., Goleva, S. B., Blokland, G. A. M., Traglia, M., Walters, R. K., Hübel, C., Coleman, J. R. I., Breen, G., Børglum, A. D., Demontis, D., Grove, J., Werge, T., Bralten, J., Bulik, C. M., Lee, P. H., Mathews, C. A., Peterson, R. E., Winham, S. J. ... Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium (2021). Examining Sex-Differentiated Genetic Effects Across Neuropsychiatric and Behavioral Traits. Biological Psychiatry, 89(12), 1127-1137. https://doi.org/10.1016/j.biopsych.2020.12.024

Martín-Encinas, E., Rubiales, G., Knudsen, B. R., Palacios, F. & Alonso, C. (2021). Fused chromeno and quinolino[1,8]naphthyridines: Synthesis and biological evaluation as topoisomerase I inhibitors and antiproliferative agents. Bioorganic and Medicinal Chemistry, 40, Article 116177. https://doi.org/10.1016/j.bmc.2021.116177

Mullins, N., Forstner, A. J., O'Connell, K. S., Coombes, B., Coleman, J. R. I., Qiao, Z., Als, T. D., Bigdeli, T. B., Børte, S., Bryois, J., Charney, A. W., Drange, O. K., Gandal, M. J., Hagenaars, S. P., Ikeda, M., Kamitaki, N., Kim, M., Krebs, K., Panagiotaropoulou, G. ... HUNT All-In Psychiatry (2021). Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nature Genetics, 53(6), 817-829. https://doi.org/10.1038/s41588-021-00857-4

Cheng, Z., Buggiotti, L., Salavati, M., Marchitelli, C., Palma-Vera, S., Wylie, A., Takeda, H., Tang, L., Crowe, M. A., Wathes, D. C. & GplusE Consortium (2021). Global transcriptomic profiles of circulating leucocytes in early lactation cows with clinical or subclinical mastitis. Molecular Biology Reports, 48, 4611-4623. https://doi.org/10.1007/s11033-021-06494-8

Milanetti, E., Miotto, M., Di Rienzo, L., Nagaraj, M., Monti, M., Golbek, T. W., Gosti, G., Roeters, S. J., Weidner, T., Otzen, D. E. & Ruocco, G. (2021). In-Silico Evidence for a Two Receptor Based Strategy of SARS-CoV-2. Frontiers in Molecular Biosciences, 8, Article 690655. https://doi.org/10.3389/fmolb.2021.690655

Otzen, D. E., Dueholm, M. S., Najarzadeh, Z., Knowles, T. P. J. & Ruggeri, F. S. (2021). In situ Sub-Cellular Identification of Functional Amyloids in Bacteria and Archaea by Infrared Nanospectroscopy. Small Methods, 5(6), Article 2001002. https://doi.org/10.1002/smtd.202001002