Institut for Molekylærbiologi og Genetik

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Peer-review'ede publikationer ved MBG - 2025

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Marzookian, K., Aliakbari, F., Hourfar, H., Sabouni, F., Otzen, D. E. & Morshedi, D. (2025). Corrigendum to "The neuroprotective effect of human umbilical cord MSCs-derived secretome against α-synuclein aggregates on the blood-brain barrier" [Int. J. Biol. Macromol. Volume 290 (2025), 140387]. International Journal of Biological Macromolecules, Artikel 149909. Advance online publication. https://doi.org/10.1016/j.ijbiomac.2025.149909
Christiansen, M. P. V. & Hammer, B. (2025). Gradient-based grand canonical optimization enabled by graph neural networks with fractional atomic existence. Machine Learning: Science and Technology, 6(4), Artikel 045049. https://doi.org/10.1088/2632-2153/ae1bf6
Kofod Petersen, A., Spin-Neto, R., Villesen, P. & Staun Larsen, L. (2025). Curvature-based 3D dental comparison to identify trauma-induced surface changes in human teeth: a forensic comparison study. Journal of Forensic Odonto-Stomatology (Online), 43(3), 49-58. https://doi.org/10.5281/zenodo.17990322
Demir, F., Kovalenko, E., Lassé, M., Svenningsen, E. B., Bernth Jensen, J. M., Billing, A. M., Groeneveld, K., Hutzfeldt, A., Nilges, L., Guerra, J. P. L., Pietrzak-Lichwa, K. J., Tan, Y., Colby, E., Hansen, A. G., Kurmasheva, N., Olagnier, D., Choi, D., Richter, M. M., Laufer, S. D. ... Rinschen, M. M. (2025). Proteolytic profiling of human plasma reveals an immunoactive complement C3 fragment. The EMBO Journal, 44(24), 7721-7758. https://doi.org/10.1038/s44318-025-00598-8
Sigurdsson, A. I., Gräf, J. F., Yang, Z., Ravn, K., Meisner, J., Thielemann, R., Webel, H., Smit, R. A. J., Niu, L., Mann, M., Vilhjalmsson, B., Neale, B. M., Holm, J.-C., Ganna, A., Hansen, T., Loos, R. J. F., Rasmussen, S. & FinnGen (2025). Complex genetic effects linked to plasma protein abundance in the UK Biobank. Nature Communications. Advance online publication. https://doi.org/10.1038/s41467-025-67235-0
Jensen, E. G., Jakobsen, T. S., Schnabolk, G., Wilson, K., Rask-Pedersen, M., Jensen, N., Andersen, G. R., Thiel, S., Aagaard, L., Rohrer, B., Askou, A. L. & Corydon, T. J. (2025). Nanobody-based gene therapy targeting complement component C3 reduces choroidal neovascularization in mice. Molecular Therapy Methods and Clinical Development, 33(4), Artikel 101620. https://doi.org/10.1016/j.omtm.2025.101620
Tsitsikli, M., Simonsen, B., Luu, T. B., Larsen, M. M., Andersen, C. G., Gysel, K., Lironi, D., Krönauer, C., Rübsam, H., Hansen, S. B., Bærentsen, R., Wulff, J. L., Johansen, S. H., Sezer, G., Stougaard, J., Andersen, K. R. & Radutoiu, S. (2025). Two residues reprogram immunity receptors for nitrogen-fixing symbiosis. Nature, 648(8093), 443-450. https://doi.org/10.1038/s41586-025-09696-3
McLain, A., Saffie-Siebert, S. R., Nielsen, N. S., Patterson, B., Scavenius, C., Enghild, J. J., Marshall, J., Baran-Rachwalska, P., Welsh, M., Sutera, F. M., Moore, L., Willoughby, C., Nesbit, M. A. & Moore, T. (2025). Topical mutant allele-specific siRNA delivery for treatment of Meesmann epithelial corneal dystrophy and elucidation of disease biomarkers. Journal of Controlled Release, 388, Artikel 114315. https://doi.org/10.1016/j.jconrel.2025.114315
Gholipourshahraki, T., Ejlskov, L., Semark, B. D., Maseras, G. T., Steinbach, J., Hansen, O. S., Pedersen, C. B., Bulik, C. M., Benros, M. E., Mortensen, P. B., Agerbo, E., Petersen, L. V. & Vilhjálmsson, B. J. (2025). Polygenic Scores and Environmental Factors in Psychiatric Disorders: Gene-Environment Interaction Analyses Using the iPSYCH Study. Research square. https://doi.org/10.21203/rs.3.rs-8201911/v1
Peña-Díaz, S., Jiang, Y., Zhang, Z., Daugberg, A., Ferreira, P., López Hernández, M., Mittal, C., Ramos, M. J., Pedersen, J. S., Dueholm, M. K. D., Qin, C., Wang, H. & Otzen, D. E. (2025). The Importance of Being Imperfect: Structure and Function of Bacterial Amyloid. Advanced Science, Artikel e17090. Advance online publication. https://doi.org/10.1002/advs.202517090
Geurts, R. & Radutoiu, S. (2025). Self-fertilizing crops: Plant Biotech’s Hardest, Most Rewarding Task. EMBO Reports, 26(23), 5644-5648. https://doi.org/10.1038/s44319-025-00618-y
Chrenková, A., Nashier, P., Madsen, C. L., Singh, M., Nielsen, J., Otzen, D. E., Enghild, J. J., Macek, B., Skjerning, R. B. & Brodersen, D. E. (2025). Homologous HipA-like kinases are controlled by internal translational initiation and genetic organisation. FEBS Letters. Advance online publication. https://doi.org/10.1002/1873-3468.70234
Ismail, S., Kubíková, J., Maichel, M., Andersen, P. & Jeske, M. (2025). Probing direct interactions between nuclear proteins in cells with nxReLo. Proceedings of the National Academy of Sciences of the United States of America, 122(48), Artikel e2518711122. https://doi.org/10.1073/pnas.2518711122
Kawamura, Y. K., Ozonov, E. A., Papasaikas, P., Kondo, T., Nguyen, N. V., Stadler, M. B., Smallwood, S. A., Koseki, H. & Peters, A. H. F. M. (2025). Preventing CpG hypermethylation in oocytes safeguards mouse development. Developmental Cell, 60(23), 3285-3303.e9. https://doi.org/10.1016/j.devcel.2025.08.005
Situ, K., Duan, H., Godin, S. K., Yang, J., McCloskey, G. Q., Naeem, B., Gillis, M. K., Zeb, M. H., Salhotra, S., Rawal, P., Patel, N., Mouliere, S. K., Chen, J., Békési, A., Pálinkás, H. L., Venkatesan, S., Green, A. M., Birkbak, N. J., Vértessy, B. G. ... Pathania, S. (2025). BRCA2 deficiency and replication stress drive APOBEC3-Mediated genomic instability. Nature Communications, 16(1), Artikel 9544. https://doi.org/10.1038/s41467-025-64578-6
García-Rodríguez, J. L., Korsgaard, U., Vissing, S. M., Paasch, T. P., Semenova, M., Vendelbo, S. L., Jensby, E. F., Williams, H. L., Salachan, P. V., Brandt, C. B., Hanimann, J., Lin, L., Zlobec, I., Sørensen, K. D., Kjems, J., Hager, H. & Kristensen, L. S. (2025). Cancer-associated fibroblasts shape the formation of budding cancer cells at the invasive front of human colorectal cancer. Communications Biology, 8(1), Artikel 1345. https://doi.org/10.1038/s42003-025-08799-x
Gobet, A. & Flygaard, R. K. (2025). CDP-alcohol phosphotransferases: Structures and function of highly diverse sub-classes within a protein family. Journal of Structural Biology, 217(4), Artikel 108266. https://doi.org/10.1016/j.jsb.2025.108266
Shyrokova, L., Egorov, A. A., Cole, A., Duque-Pedraza, J. J., Tyagi, A., Ernits, K., Mets, T., Kurata, T., Juozapaitis, J., Yang, A. L. J., Ibarra Chavez, R., Graversgaard Henriksen, F. O., Lassen, S., Atkinson, G. C., Hauryliuk, V. & Johansson, M. J. O. (2025). Characterization of five environmental phages infecting Escherichia coli K-12 isolated during a phage biology training course. Microbiology Spectrum, 13(12), Artikel e0227425. https://doi.org/10.1128/spectrum.02274-25
Zhang, S., Ma, J., Riera Belles, M., Besenbacher, S., Niskanen, J. E., Salokorpi, N., Hundi, S., Hytönen, M. K., Zhou, T., Li, G.-M., Ostrander, E. A., Schierup, M. H., Lohi, H. & Wang, G.-D. (2025). Determinants of de novo mutations in extended pedigrees of 43 dog breeds. Genome Biology, 26(1), Artikel 305. https://doi.org/10.1186/s13059-025-03804-2
Zhang, T., Bär, J., Risberg, L., Gómez Mejia, A., Hammar, H., Löffler, S., Otzen, D. E., Andreasen, M., Meyer, R. L., Melican, K., Zinkernagel, A. S. & Richter-Dahlfors, A. (2025). Dynamic visualization of extracellular matrix components in S. aureus colony biofilms reveals functional amyloids leading to the formation of cap-like structures. Biofilm, 10, Artikel 100318. https://doi.org/10.1016/j.bioflm.2025.100318
Garde, C., Pavlidis, M. A., Garces, P., Lange, E. J., Ramarathinam, S. H., Sokač, M., Pandey, K., Faridi, P., Ahrenfeldt, J., Chung, S., Friis, S., Kleine-Kohlbrecher, D., Birkbak, N. J., Kringelum, J. V., Rønø, B., Purcell, A. W. & Trolle, T. (2025). Endogenous viral elements constitute a complementary source of antigens for personalized cancer vaccines. NPJ vaccines, 10(1), Artikel 54. https://doi.org/10.1038/s41541-025-01107-y
Rasmussen, C. L. M., Frederiksen, S. F., Heegaard, C. W., Thomsen, M. S., Hede, E., Laczek, B., Körbelin, J., Wüstner, D., Thomsen, L. B., Schwaninger, M., Jensen, O. N., Moos, T. & Burkhart, A. (2025). Endothelial and neuronal engagement by AAV-BR1 gene therapy alleviates neurological symptoms and lipid deposition in a mouse model of Niemann-Pick type C2. Fluids and Barriers of the CNS, 22(1), Artikel 13. https://doi.org/10.1186/s12987-025-00621-4
Qin, Q., Wei, P., Usman, S., Ahamefule, C. S., Jin, C., Wang, B., Yan, K., van Aalten, D. M. F. & Fang, W. (2025). Gfa1 (glutamine fructose-6-phosphate aminotransferase) is essential for Aspergillus fumigatus growth and virulence. BMC Biology, 23(1), Artikel 80. https://doi.org/10.1186/s12915-025-02184-0
Gómez-Repollés, A., Villa-Rodríguez, E., Blahovska, Z., Ferguson, S. & Radutoiu, S. (2025). High-quality genome assemblies of 152 root commensal bacteria from the model legume Lotus japonicus. Scientific Data, 12(1), Artikel 1793. https://doi.org/10.1038/s41597-025-06078-2
Yamamoto, S., Nakajima, R., Hirai, Y., Kawamura, Y. K., Makita, Y., Kitazawa, T., Kimura, M. & Kitazawa, Y. (2025). Hydroxylated iodinated boron clusters: a tunable platform for enhanced membrane transport and biocompatibility. Chemical Communications. Advance online publication. https://doi.org/10.1039/d5cc04085j
Porsborg, P. S., Charmouh, A. P., Singh, V. K., Winge, S. B., Hvilsom, C., Oroperv, C., Hansen, L. T., Berner, J. A., Pelizzola, M., Laurentino, S., Neuhaus, N., Hobolth, A., Bataillon, T., Besenbacher, S., Almstrup, K. & Schierup, M. H. (2025). Long-read sequencing of primate testis and human sperm allows identification of recombination events in individuals. Nature Communications, 16(1), Artikel 10337. https://doi.org/10.1038/s41467-025-65248-3
Morin, M., Yin, W., MacLean, H., Devlin, B., Reichenberg, A., Swan, S. H., Buxbaum, J. D., Schendel, D., Persson, M., Laursen, T. M., Kolevzon, A., Grove, J., Klei, L., Roeder, K. & Sandin, S. (2025). Maternal body mass index in early pregnancy and autism in offspring: a population-based cohort study in Sweden and Denmark. BMC Medicine, 23(1), Artikel 620. https://doi.org/10.1186/s12916-025-04487-z
Hjelholt, A. J., Gholipourshahraki, T., Bai, Z., Shrestha, M., Kjolby, M., Sørensen, P. & Rohde, P. D. (2025). mLeveraging genetic correlations to prioritize drug groups for repurposing in type 2 diabetes. Pharmacogenomics Journal, 25(6), Artikel 33. https://doi.org/10.1038/s41397-025-00392-z
Hansen, S. B., Bartual, S. G., Yuan, H., Raimi, O. G., Gorelik, A., Ferenbach, A. T., Lytje, K., Pedersen, J. S., Drace, T., Boesen, T. & van Aalten, D. M. F. (2025). Multi-domain O-GlcNAcase structures reveal allosteric regulatory mechanisms. Nature Communications, 16(1), Artikel 8828. https://doi.org/10.1038/s41467-025-63893-2
Bryzek, D., Gasiorek, A., Kowalczyk, D., Santocki, M., Ciaston, I., Dobosz, E., Kolaczkowska, E., Kjøge, K., Kantyka, T., Lech, M., Potempa, B., Enghild, J. J., Potempa, J. & Koziel, J. (2025). Non-classical neutrophil extracellular traps induced by PAR2-signaling proteases. Cell Death & Disease, 16(1), Artikel 109. https://doi.org/10.1038/s41419-025-07428-z
Andersen-Civil, A. I. S., Mantel, M., Soh, J., Mostowy, S., Brugman, S. & Vanwalleghem, G. C. (2025). Novel and unscrutinized immune entities of the zebrafish gut. FEBS Letters, 599(23), 3444-3455. https://doi.org/10.1002/1873-3468.70161
Waligórska, I., Żak, K. M., Mikrut, N., Budziaszek, J., Medviediev, V., Bielecka, E., Kantyka, T., Kozieł, J., Thøgersen, I. B., Enghild, J. J., Grudnik, P., Potempa, J. & Książek, M. (2025). Periodontopathogens degrade angiotensin I from the human renin-angiotensin system through surface-attached proteases. Scientific Reports, 15(1), Artikel 43309. https://doi.org/10.1038/s41598-025-27891-0
Wimberley, T., Plana-Ripoll, O., Pedersen, C. B., Pedersen, M. G., Dreier, J. W., Christensen, J., Horsdal, H. T., Astrup, A., Thompson, W. K., Helenius, D., McGrath, J. J., Wray, N. R., Petersen, L. V., Vilhjálmsson, B., Mortensen, P. B. & Agerbo, E. (2025). Population-representative inference for primary and secondary outcomes in extended case-cohort designs. Discover public health, 22(1), Artikel 599. https://doi.org/10.1186/s12982-025-00888-w
Gobet, A., Moissonnier, L., Zarkadas, E., Magnard, S., Bettler, E., Martin, J., Terreux, R., Schoehn, G., Orelle, C., Jault, J. M., Falson, P. & Chaptal, V. (2025). Rhodamine6G and Hœchst33342 narrow BmrA conformational spectrum for a more efficient use of ATP. Nature Communications, 16(1), Artikel 1745. https://doi.org/10.1038/s41467-025-56849-z
Thorsen, T. S., Kulkarni, Y., Sykes, D. A., Bøggild, A., Drace, T., Hompluem, P., Iliopoulos-Tsoutsouvas, C., Nikas, S. P., Daver, H., Makriyannis, A., Nissen, P., Gajhede, M., Veprintsev, D. B., Boesen, T., Kastrup, J. S. & Gloriam, D. E. (2025). Structural basis of THC analog activity at the Cannabinoid 1 receptor. Nature Communications, 16(1), Artikel 486. https://doi.org/10.1038/s41467-024-55808-4
Zaheer, S., Baindoor, S., Connolly, N. M. C., Siebenbrodt, K., Bauer, S., Rosenow, F., Andersen, J. S., Venø, M. T., Kjems, J., Henshall, D. C. & Prehn, J. H. M. (2025). Temporal Dynamics of tsRNA Regulation Mark an Abrupt Transition After Epileptogenesis. Journal of Neurochemistry, 169(12), Artikel e70317. https://doi.org/10.1111/jnc.70317
Wang, X., Nursyifa, C., Aninta, S. G., Garcia-Erill, G., Bertola, L. D., Khan, A., Kuja, J., Hanghøj, K., Meisner, J., Bøggild, T., Bradshaw, C. J. A., Al-Chaer, A., Persada, A. P., Priyono, D. S., Tribudi, Y. A., Sudrajad, P., Gaina, C. D., Jiang, Y., Lenstra, J. A. ... Heller, R. (2025). The genetic diversity of Indonesian cattle has been shaped by multiple introductions and adaptive introgression. Nature Communications, 16(1), Artikel 8192. https://doi.org/10.1038/s41467-025-62692-z
Montiel, J., García-Soto, I., Monroy-Morales, E., Lace, B., Robledo-Gamboa, M., Vestergaard, M., Sandal, N., Ott, T. & Stougaard, J. (2025). The Lotus japonicus alpha-expansin EXPA1 is recruited during intracellular and intercellular rhizobial colonization. Plant Journal, 124(5), Artikel e70639. https://doi.org/10.1111/tpj.70639
Novosylna, O., Shalak, V., Dąbrowska, K., Patmanidis, I., Lozhko, D., Bondarchuk, T., Schiøtt, B., Pedersen, J. S., Knudsen, C. R., Nissen, P., Dadlez, M. & Negrutskii, B. (2025). Dynamics and structural features of the eEF1A1 and eEF1A2 paralogs. Nucleic Acids Research, 53(21), Artikel gkaf1177. https://doi.org/10.1093/nar/gkaf1177
Jiang, Y. & Kjems, J. (2025). RNA denaturation underlies circular RNA separation. Nucleic Acids Research, 53(21), Artikel gkaf1160. https://doi.org/10.1093/nar/gkaf1160
Yu, X., Liu, C. D., Shen, S., Kim, E. S., Liu, Z., Zhang, H., Sun, N., Liu, Y., Martensen, P. M., Huang, Y. & Guo, H. (2025). Interferon alpha-inducible protein 27 (IFI27) inhibits hepatitis B virus (HBV) transcription through downregulating cellular transcription factor C/EBPα. Journal of Virology, 99(11), e0150925. https://doi.org/10.1128/jvi.01509-25
Olsen, L. R., Odinokov, D., Holsting, J. Q., Kondrup, K., Iisager, L., Rusan, M., Buus, S., Laursen, B. E., Borre, M., Jochumsen, M. R., Bouchelouche, K., Frydendahl, A., Rasmussen, M. H., Henriksen, T. V., Nesic, M., Demuth, C., Lindskrog, S. V., Nordentoft, I., Lamy, P. ... Besenbacher, S. (2025). Cross-dataset pan-cancer detection by correlating cell-free DNA fragment coverage with open chromatin sites across cell types. Nature Communications, 16(1), Artikel 11522. https://doi.org/10.1038/s41467-025-66503-3
Hussein, A., Zhang, X., Pedersen, B. P. & Stokes, D. L. (2025). Conduction pathway for potassium through the Escherichia coli pump KdpFABC. eLife, 14. https://doi.org/10.7554/eLife.107397
Jansen, S. A. H., Dreyer, L. S. A., van Basten, J., Yao, Y., Otzen, D. E., de Greef, T. F. A., Knowles, T. P. J., Meijer, E. W. & Erkamp, N. A. (2025). PhaseXplorer Creates High-Dimensional Phase Diagrams with Closed-Loop Active Learning. ACS Nano, 19(45), 38981-38989. https://doi.org/10.1021/acsnano.5c07268
Demontis, D., Duan, J., Hsu, Y.-H. H., Pintacuda, G., Grove, J., Nielsen, T. T., Thirstrup, J., Martorana, M., Botts, T., Satterstrom, F. K., Bybjerg-Grauholm, J., Tsai, J. H. Y., Glerup, S., Hoogman, M., Buitelaar, J., Klein, M., Ziegler, G. C., Jacob, C., Grimm, O. ... Børglum, A. D. (2025). Rare genetic variants confer a high risk of ADHD and implicate neuronal biology. Nature. Advance online publication. https://doi.org/10.1038/s41586-025-09702-8
Talay, A., Belikov, A. V., To, P. K. P., Alfatemi, H. H., Alon, U., Deelen, J., Ewald, C. Y., Gems, D., Gorbunova, V., Gruber, J., Hägg, S., Hemming, J., Horvath, S., Kaya, A., Lewis, C. J., Maier, A. B., Marinova, M. B., Pawelec, G., Peleg, S. ... de Magalhães, J. P. (2025). Open problems in ageing science: a roadmap for biogerontology. GeroScience. Advance online publication. https://doi.org/10.1007/s11357-025-01964-4
Bærentsen, R. L., Kronborg, K., Brodersen, D. E. & Zhang, Y. E. (2025). Catalytic mechanism and differential alarmone regulation of a conserved stringent nucleosidase. Structure. Advance online publication. https://doi.org/10.1016/j.str.2025.10.012
Gabs, E., Aalto-Setälä, E., Välisaari, A., Malinen, A. M., Jensen, T. H., McLaughlin, S. H., Passmore, L. A. & Turtola, M. (2025). A kinetic ruler controls mRNA poly(A) tail length. Genes & Development, 39(21-22), 1377-1394. https://doi.org/10.1101/gad.352912.125
Muñoz-Juan, A., Laromaine, A., Yuste, V. J. & Dalfó, E. (2025). Assessing Gastrointestinal Motility in Caenorhabditis elegans RAC1/CED-10 Mutants as a Tool to Study Early Parkinson's Disease. Journal of Visualized Experiments, 2025(225), Artikel e69278. https://doi.org/10.3791/69278
Mishra, A., Golbek, T. W., Thomassen, A. B., Zuzic, L., Schmüser, L., Saeed, K. H., Madzharova, F., Nielsen, J., Schiøtt, B., Otzen, D. E. & Weidner, T. (2025). Pathological Folding of α-Synuclein on Polystyrene Nanoplastic Revealed by Sum Frequency Scattering and 2D Infrared Spectroscopy. The Journal of Physical Chemistry Letters, 16(45), 11893-11900. https://doi.org/10.1021/acs.jpclett.5c02526

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Peer-review'ede publikationer ved MBG - alle år

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Bicer, D., Matsuoka, R., Moumbock, A. F. A., Sukumar, P., Suades, A., Cheruvara, H., Quigley, A., Drew, D., Pardon, E., Steyaert, J., Henderson, P. J. F., Caffrey, M., Griese, J. J. & Nji, E. (2026). Structural basis of specific lysine transport by Pseudomonas aeruginosa permease LysP. Nature Communications, 17(1), Artikel 37. https://doi.org/10.1038/s41467-025-66618-7
Madsen, P. N., Jørgensen, P. B., Clausen, M. V. & Knudsen, C. R. (2026). Optimized purification workflow for advanced eEF1A studies: Impact of His-tagging on stability, functionality, and yield. Analytical Biochemistry, 710, Artikel 116017. https://doi.org/10.1016/j.ab.2025.116017
Otzen, D. E., Gamon, L. F., Hägglund, P., Nielsen, J., Pedersen, J. N., Nybo, T., Nowak, J. S., Amstrup, S. K., Pirhaghi, M. & Davies, M. J. (2026). Nitrated products formed on α-synuclein are preferentially incorporated into oligomers but excluded from fibrils: A mechanism for accumulation of neurotoxic species. Biochimica et Biophysica Acta - Proteins and Proteomics, 1874(2), Artikel 141118. https://doi.org/10.1016/j.bbapap.2025.141118
Idorn, M., Ding, X., Fruhwürth, S., Holste, S., Reinert, L. S., Skoven, C. S., Türner-Stenström, K., Schmitz, A., Vendelbo, M. H., Ulhøi, B. P., Vizlin-Hodzic, D., Wefelmeyer, M., Narita, R., Kroese, L. J., Huijbers, I. J., Møhlenberg, M., Hollensen, A. K., Lai, X., Iversen, M. B. ... Paludan, S. R. (2026). Role for NF-κB in herpes encephalitis pathology in mice genocopying an inborn error of IRF3-IFN immunity. The Journal of Experimental Medicine, 223(1). https://doi.org/10.1084/jem.20250064
Ge, F., Wang, Y., Liu, X., Munk-Olsen, T., Madsen, K. B., Pedersen, E. M., Albiñana, C., Agerbo, E., Bulik, C. M., Petersen, L. V., Valdimarsdottir, U. A. & Vilhjálmsson, B. J. (2026). Association Between Maternal Genome-Wide Polygenic Scores for Psychiatric and Neurodevelopmental Disorders and Adverse Perinatal Events: A Danish Population-Based Study. Biological Psychiatry Global Open Science, 6(1), Artikel 100613. https://doi.org/10.1016/j.bpsgos.2025.100613
López Hernández, M., Scavenius, C., Otzen, D. E. & Pedersen, J. S. (2026). Divergent effects of anionic surfactants on laundry enzymes: Structural stability, activity modulation, and self-cleavage mechanisms. International Journal of Biological Macromolecules, 335(1), Artikel 149069. https://doi.org/10.1016/j.ijbiomac.2025.149069
Goleva, S. B., Leu, C., Anne Feng, Y. C., Burstein, D., Venkatesh, S., Birnbaum, R., Rajagopal, V. M., Straub, P., Christensen, J., Bautista, J. F., Busch, R. M., Najm, I. M., Grove, J., Børglum, A. D., Voloudakis, G., Roussos, P., Smoller, J., Lal, D. & Davis, L. K. (2026). Multisite, Multiancestry Genome-Wide Association Study Meta-Analysis of Functional Seizure Disorder in a Hospital Sample of 675,680 Patients. Biological Psychiatry Global Open Science, 6(1), Artikel 100604. https://doi.org/10.1016/j.bpsgos.2025.100604
Dybdahl Krebs, M., Appadurai, V., Georgii Hellberg, K.-L., Ohlsson, H., Steinbach, J., Pedersen, E., Werge, T., Sundquist, J., Sundquist, K., Border, R., Cai, N., Zaitlen, N., Dahl, A., Vilhjalmsson, B., Flint, J., Bacanu, S.-A., Kendler, K. S., Schork, A. J. & iPSYCH Study Consortium (2026). The relationship between genotype- and phenotype-based estimates of genetic liability to psychiatric disorders, in practice and in theory. American Journal of Human Genetics, 113(1), 184-201. https://doi.org/10.1016/j.ajhg.2025.11.016
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Marzookian, K., Aliakbari, F., Hourfar, H., Sabouni, F., Otzen, D. E. & Morshedi, D. (2025). Corrigendum to "The neuroprotective effect of human umbilical cord MSCs-derived secretome against α-synuclein aggregates on the blood-brain barrier" [Int. J. Biol. Macromol. Volume 290 (2025), 140387]. International Journal of Biological Macromolecules, Artikel 149909. Advance online publication. https://doi.org/10.1016/j.ijbiomac.2025.149909
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Chrenková, A., Nashier, P., Madsen, C. L., Singh, M., Nielsen, J., Otzen, D. E., Enghild, J. J., Macek, B., Skjerning, R. B. & Brodersen, D. E. (2025). Homologous HipA-like kinases are controlled by internal translational initiation and genetic organisation. FEBS Letters. Advance online publication. https://doi.org/10.1002/1873-3468.70234
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Kawamura, Y. K., Ozonov, E. A., Papasaikas, P., Kondo, T., Nguyen, N. V., Stadler, M. B., Smallwood, S. A., Koseki, H. & Peters, A. H. F. M. (2025). Preventing CpG hypermethylation in oocytes safeguards mouse development. Developmental Cell, 60(23), 3285-3303.e9. https://doi.org/10.1016/j.devcel.2025.08.005
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García-Rodríguez, J. L., Korsgaard, U., Vissing, S. M., Paasch, T. P., Semenova, M., Vendelbo, S. L., Jensby, E. F., Williams, H. L., Salachan, P. V., Brandt, C. B., Hanimann, J., Lin, L., Zlobec, I., Sørensen, K. D., Kjems, J., Hager, H. & Kristensen, L. S. (2025). Cancer-associated fibroblasts shape the formation of budding cancer cells at the invasive front of human colorectal cancer. Communications Biology, 8(1), Artikel 1345. https://doi.org/10.1038/s42003-025-08799-x
Gobet, A. & Flygaard, R. K. (2025). CDP-alcohol phosphotransferases: Structures and function of highly diverse sub-classes within a protein family. Journal of Structural Biology, 217(4), Artikel 108266. https://doi.org/10.1016/j.jsb.2025.108266
Shyrokova, L., Egorov, A. A., Cole, A., Duque-Pedraza, J. J., Tyagi, A., Ernits, K., Mets, T., Kurata, T., Juozapaitis, J., Yang, A. L. J., Ibarra Chavez, R., Graversgaard Henriksen, F. O., Lassen, S., Atkinson, G. C., Hauryliuk, V. & Johansson, M. J. O. (2025). Characterization of five environmental phages infecting Escherichia coli K-12 isolated during a phage biology training course. Microbiology Spectrum, 13(12), Artikel e0227425. https://doi.org/10.1128/spectrum.02274-25
Zhang, S., Ma, J., Riera Belles, M., Besenbacher, S., Niskanen, J. E., Salokorpi, N., Hundi, S., Hytönen, M. K., Zhou, T., Li, G.-M., Ostrander, E. A., Schierup, M. H., Lohi, H. & Wang, G.-D. (2025). Determinants of de novo mutations in extended pedigrees of 43 dog breeds. Genome Biology, 26(1), Artikel 305. https://doi.org/10.1186/s13059-025-03804-2
Zhang, T., Bär, J., Risberg, L., Gómez Mejia, A., Hammar, H., Löffler, S., Otzen, D. E., Andreasen, M., Meyer, R. L., Melican, K., Zinkernagel, A. S. & Richter-Dahlfors, A. (2025). Dynamic visualization of extracellular matrix components in S. aureus colony biofilms reveals functional amyloids leading to the formation of cap-like structures. Biofilm, 10, Artikel 100318. https://doi.org/10.1016/j.bioflm.2025.100318
Garde, C., Pavlidis, M. A., Garces, P., Lange, E. J., Ramarathinam, S. H., Sokač, M., Pandey, K., Faridi, P., Ahrenfeldt, J., Chung, S., Friis, S., Kleine-Kohlbrecher, D., Birkbak, N. J., Kringelum, J. V., Rønø, B., Purcell, A. W. & Trolle, T. (2025). Endogenous viral elements constitute a complementary source of antigens for personalized cancer vaccines. NPJ vaccines, 10(1), Artikel 54. https://doi.org/10.1038/s41541-025-01107-y
Rasmussen, C. L. M., Frederiksen, S. F., Heegaard, C. W., Thomsen, M. S., Hede, E., Laczek, B., Körbelin, J., Wüstner, D., Thomsen, L. B., Schwaninger, M., Jensen, O. N., Moos, T. & Burkhart, A. (2025). Endothelial and neuronal engagement by AAV-BR1 gene therapy alleviates neurological symptoms and lipid deposition in a mouse model of Niemann-Pick type C2. Fluids and Barriers of the CNS, 22(1), Artikel 13. https://doi.org/10.1186/s12987-025-00621-4
Qin, Q., Wei, P., Usman, S., Ahamefule, C. S., Jin, C., Wang, B., Yan, K., van Aalten, D. M. F. & Fang, W. (2025). Gfa1 (glutamine fructose-6-phosphate aminotransferase) is essential for Aspergillus fumigatus growth and virulence. BMC Biology, 23(1), Artikel 80. https://doi.org/10.1186/s12915-025-02184-0
Gómez-Repollés, A., Villa-Rodríguez, E., Blahovska, Z., Ferguson, S. & Radutoiu, S. (2025). High-quality genome assemblies of 152 root commensal bacteria from the model legume Lotus japonicus. Scientific Data, 12(1), Artikel 1793. https://doi.org/10.1038/s41597-025-06078-2
Yamamoto, S., Nakajima, R., Hirai, Y., Kawamura, Y. K., Makita, Y., Kitazawa, T., Kimura, M. & Kitazawa, Y. (2025). Hydroxylated iodinated boron clusters: a tunable platform for enhanced membrane transport and biocompatibility. Chemical Communications. Advance online publication. https://doi.org/10.1039/d5cc04085j
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Morin, M., Yin, W., MacLean, H., Devlin, B., Reichenberg, A., Swan, S. H., Buxbaum, J. D., Schendel, D., Persson, M., Laursen, T. M., Kolevzon, A., Grove, J., Klei, L., Roeder, K. & Sandin, S. (2025). Maternal body mass index in early pregnancy and autism in offspring: a population-based cohort study in Sweden and Denmark. BMC Medicine, 23(1), Artikel 620. https://doi.org/10.1186/s12916-025-04487-z
Hjelholt, A. J., Gholipourshahraki, T., Bai, Z., Shrestha, M., Kjolby, M., Sørensen, P. & Rohde, P. D. (2025). mLeveraging genetic correlations to prioritize drug groups for repurposing in type 2 diabetes. Pharmacogenomics Journal, 25(6), Artikel 33. https://doi.org/10.1038/s41397-025-00392-z
Hansen, S. B., Bartual, S. G., Yuan, H., Raimi, O. G., Gorelik, A., Ferenbach, A. T., Lytje, K., Pedersen, J. S., Drace, T., Boesen, T. & van Aalten, D. M. F. (2025). Multi-domain O-GlcNAcase structures reveal allosteric regulatory mechanisms. Nature Communications, 16(1), Artikel 8828. https://doi.org/10.1038/s41467-025-63893-2
Bryzek, D., Gasiorek, A., Kowalczyk, D., Santocki, M., Ciaston, I., Dobosz, E., Kolaczkowska, E., Kjøge, K., Kantyka, T., Lech, M., Potempa, B., Enghild, J. J., Potempa, J. & Koziel, J. (2025). Non-classical neutrophil extracellular traps induced by PAR2-signaling proteases. Cell Death & Disease, 16(1), Artikel 109. https://doi.org/10.1038/s41419-025-07428-z
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Gobet, A., Moissonnier, L., Zarkadas, E., Magnard, S., Bettler, E., Martin, J., Terreux, R., Schoehn, G., Orelle, C., Jault, J. M., Falson, P. & Chaptal, V. (2025). Rhodamine6G and Hœchst33342 narrow BmrA conformational spectrum for a more efficient use of ATP. Nature Communications, 16(1), Artikel 1745. https://doi.org/10.1038/s41467-025-56849-z
Thorsen, T. S., Kulkarni, Y., Sykes, D. A., Bøggild, A., Drace, T., Hompluem, P., Iliopoulos-Tsoutsouvas, C., Nikas, S. P., Daver, H., Makriyannis, A., Nissen, P., Gajhede, M., Veprintsev, D. B., Boesen, T., Kastrup, J. S. & Gloriam, D. E. (2025). Structural basis of THC analog activity at the Cannabinoid 1 receptor. Nature Communications, 16(1), Artikel 486. https://doi.org/10.1038/s41467-024-55808-4
Zaheer, S., Baindoor, S., Connolly, N. M. C., Siebenbrodt, K., Bauer, S., Rosenow, F., Andersen, J. S., Venø, M. T., Kjems, J., Henshall, D. C. & Prehn, J. H. M. (2025). Temporal Dynamics of tsRNA Regulation Mark an Abrupt Transition After Epileptogenesis. Journal of Neurochemistry, 169(12), Artikel e70317. https://doi.org/10.1111/jnc.70317
Wang, X., Nursyifa, C., Aninta, S. G., Garcia-Erill, G., Bertola, L. D., Khan, A., Kuja, J., Hanghøj, K., Meisner, J., Bøggild, T., Bradshaw, C. J. A., Al-Chaer, A., Persada, A. P., Priyono, D. S., Tribudi, Y. A., Sudrajad, P., Gaina, C. D., Jiang, Y., Lenstra, J. A. ... Heller, R. (2025). The genetic diversity of Indonesian cattle has been shaped by multiple introductions and adaptive introgression. Nature Communications, 16(1), Artikel 8192. https://doi.org/10.1038/s41467-025-62692-z
Montiel, J., García-Soto, I., Monroy-Morales, E., Lace, B., Robledo-Gamboa, M., Vestergaard, M., Sandal, N., Ott, T. & Stougaard, J. (2025). The Lotus japonicus alpha-expansin EXPA1 is recruited during intracellular and intercellular rhizobial colonization. Plant Journal, 124(5), Artikel e70639. https://doi.org/10.1111/tpj.70639
Novosylna, O., Shalak, V., Dąbrowska, K., Patmanidis, I., Lozhko, D., Bondarchuk, T., Schiøtt, B., Pedersen, J. S., Knudsen, C. R., Nissen, P., Dadlez, M. & Negrutskii, B. (2025). Dynamics and structural features of the eEF1A1 and eEF1A2 paralogs. Nucleic Acids Research, 53(21), Artikel gkaf1177. https://doi.org/10.1093/nar/gkaf1177
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Yu, X., Liu, C. D., Shen, S., Kim, E. S., Liu, Z., Zhang, H., Sun, N., Liu, Y., Martensen, P. M., Huang, Y. & Guo, H. (2025). Interferon alpha-inducible protein 27 (IFI27) inhibits hepatitis B virus (HBV) transcription through downregulating cellular transcription factor C/EBPα. Journal of Virology, 99(11), e0150925. https://doi.org/10.1128/jvi.01509-25

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Lisbeth Heilesen