Publications

10 selected publications from the last ten years:

1. Jonas D. Elsborg, Sebastian H. N. Munk, Zita Fábian, Alba Adelantado-Rubio, Victor Imburchia, Ivo A. Hendriks, Sara C. Larsen, Jiri Bartek, Sébastien Huet, Julien P. Duxin, Apolinar Maya- Mendoza, Michael L. Nielsen. “PARP1 auto-modification promotes faithful Okazaki fragment processing and limits replication fork speed” Molecular Cell, 2025, Online October 2nd

2. Alexandra K.L.F.S. Rebak, Sara C. Buch-Larsen, Ivo A. Hendriks, Jonas D. Elsborg, Rebecca Kirsch, Nadezhda Tsankova Doncheva, Lars Juhl Jensen, Maria Christophorou and Michael L. Nielsen. “A quantitative and site-specific atlas of the citrullinome reveals widespread existence of citrullination and insights into PADI4 substrates”, Nature Structural & Molecular Biology, 2024

3. Meeli Mullari, Nicolas Fossat, Niels H. Skotte, Andrea Asenjo-Martinez, David T. Humphreys, Jens Buhk, Agnete Kirkeby, Troels K. H. Scheel, and Michael L. Nielsen. “The RNA-binding protein atlas of the mammalian brain uncovers a role for RBM5 in Huntington’s disease”, Nature Communication, 2023,

4. Massimo Carraro, Ivo A Hendriks, Colin M. Hammond, Victor Solis, Moritz Völker-Albert, Jonas D Elsborg, Melanie Weisser, Christos Spanos, Guillermo Motoya, Juri Rappsilber, Axel Imhof, Michael L. Nielsen*, Anja Groth*, “Mapping the histone chaperone network unveils DAXX-mediated heterochromatin assembly”, Molecular Cell, 2023 *Shared correspondence

5. Camilla S. Colding-Christensen, Ellen S. Kakulidis, Javier A. Gomez, Ivo A. Hendriks, Connor Arkinson, Agnieszka Gambus, Niels Mailand, Julien P. Duxin, Michael L. Nielsen. “Profiling ubiquitin signaling with UBIMAX reveals DNA damage- and SCFβTRCP-dependent ubiquitylation of the actin-organizing protein Dbn1”, Nature Communications, 2023

6. Ivo A. Hendriks, Sara C. Buch-Larsen, Evgeniia Prokhorova, Alexandra K.L.F.S. Rebak, Ivan Ahel & Michael L. Nielsen,. “The regulatory landscape of the human HPF1- and ARH3-dependent ADP- ribosylome”, Nature Communications, 2021

7. Ivo A. Hendriks, David Lyon, Dan Su, Jeremy A. Daniel, Lars J. Jensen and Michael L. Nielsen. ”Site-specific characterization of endogenous SUMOylation across species and organs”, Nature Communications, 2018

8. Ivo A. Hendriks, David Lyon, Clifford Young, Lars J. Jensen, Alfred C.O. Vertegaal and Michael L. Nielsen.” Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation”, Nature Structural & Molecular Biology, 2017

9. Sara C. Larsen, Kathrine B. Sylvestersen, Andres Mund, Maria V. Madsen, David Lyon, Jeremy A. Daniel, Lars Juhl-Jensen, and Michael L. Nielsen, “Proteome-wide analysis of arginine mono-methylation reveals wide-spread occurrence in human cells”, Science Signaling, 2016

10. Rita Martello, Mario Leutert, Stephanie Jungmichel, Vera Bilan, Sara C. Larsen, Clifford Young, Michael O. Hottiger and Michael L. Nielsen,“Proteome-wide identification of the endogenous ADP-ribosylome of mammalian cells and tissue”, Nature Communications, 2016

Peer-reviewed articles

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Klimovskaia, I. M., Young, C., Strømme, C. B., Menard, P., Jasencakova, Z., Mejlvang, J., Ask, K., Ploug, M., Nielsen, M. L., Jensen, O. N. & Groth, A. (2014). Tousled-like kinases phosphorylate Asf1 to promote histone supply during DNA replication. Nature Communications, 5, Article 3394. https://doi.org/10.1038/ncomms4394

Sylvestersen, K. B., Young, C. & Nielsen, M. L. (2013). Advances in characterizing ubiquitylation sites by mass spectrometry. Current Opinion in Chemical Biology, 17(1), 49-58. https://doi.org/10.1016/j.cbpa.2012.12.009

Cepeda, D., Ng, H. F., Sharifi, H. R., Mahmoudi, S., Cerrato, V. S., Fredlund, E., Magnusson, K., Nilsson, H., Malyukova, A., Rantala, J., Klevebring, D., Viñals, F., Bhaskaran, N., Zakaria, S. M., Rahmanto, A. S., Grotegut, S., Nielsen, M. L., Szigyarto, C. A. K., Sun, D. ... Sangfelt, O. (2013). CDK-mediated activation of the SCF^FBXO28 ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer. EMBO Molecular Medicine, 5(7), 999-1018. https://doi.org/10.1002/emmm.201202341

Jungmichel, S., Rosenthal, F., Altmeyer, M., Lukas, J., Hottiger, M. O. & Nielsen, M. L. (2013). Proteome-wide identification of poly(ADP-Ribosyl)ation targets in different genotoxic stress responses. Molecular Cell, 52(2), 272-285. https://doi.org/10.1016/j.molcel.2013.08.026

Poulsen, J. W., Madsen, C. T., Young, C., Poulsen, F. M. & Nielsen, M. L. (2013). Using guanidine-hydrochloride for fast and efficient protein digestion and single-step affinity-purification mass spectrometry. Journal of proteome Research, 12(2), 1020-1030. https://doi.org/10.1021/pr300883y

Displaying results 51 to 55 out of 81

[Translate to English:] Selected publications

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Revised 23.04.2026