Institut for Molekylærbiologi og Genetik

Aarhus Universitets segl

Publications

Peer-reviewed artikler

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Wagner, S. A., Beli, P., Weinert, B. T., Nielsen, M. L., Cox, J., Mann, M. & Choudhary, C. (2011). A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. Molecular and Cellular Proteomics, 10(10). https://doi.org/10.1074/mcp.m111.013284
Marín-Vicente, C., Guerrero-Valero, M., Nielsen, M. L., Savitski, M. M., Gómez-Fernández, J. C., Zubarev, R. A. & Corbalán-García, S. (2011). ATP enhances neuronal differentiation of PC12 cells by activating PKCα interactions with cytoskeletal proteins. Journal of proteome Research, 10(2), 529-540. https://doi.org/10.1021/pr100742r
Danielsen, J. M. R., Sylvestersen, K. B., Bekker-Jensen, S., Szklarczyk, D., Poulsen, J. W., Horn, H., Jensen, L. J., Mailand, N. & Nielsen, M. L. (2011). Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. Molecular and Cellular Proteomics, 10(3). https://doi.org/10.1074/mcp.M110.003590
Vesterlund, M., Zadjali, F., Persson, T., Nielsen, M. L., Kessler, B. M., Norstedt, G. & Flores-Morales, A. (2011). The SOCS2 ubiquitin ligase complex regulates growth hormone receptor levels. PLoS One, 6(9), Artikel e25358. https://doi.org/10.1371/journal.pone.0025358
Choudhary, C., Kumar, C., Gnad, F., Nielsen, M. L., Rehman, M., Walther, T. C., Olsen, J. V. & Mann, M. (2009). Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science, 325(5942), 834-840. https://doi.org/10.1126/science.1175371
Fäith, M., Savitski, M. M., Nielsen, M. L., Kjeldsen, F., Andren, P. E. & Zubarev, R. A. (2008). Analytical utility of small neutral losses from reduced species in electron capture dissociation studied using SwedECD database. Analytical Chemistry, 80(21), 8089-8094. https://doi.org/10.1021/ac800944u
De Godoy, L. M. F., Olsen, J. V., Cox, J., Nielsen, M. L., Hubner, N. C., Fröhlich, F., Walther, T. C. & Mann, M. (2008). Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast. Nature, 455(7217), 1251-1254. https://doi.org/10.1038/nature07341
Zubarev, R. A., Nielsen, M. L., Fung, E. M., Savitski, M. M., Kel-Margoulis, O., Wingender, E. & Kel, A. (2008). Identification of dominant signaling pathways from proteomics expression data. Journal of Proteomics, 71(1), 89-96. https://doi.org/10.1016/j.jprot.2008.01.004
Frank, A. M., Savitski, M. M., Nielsen, M. L., Zubarev, R. A. & Pevzner, P. A. (2007). De novo peptide sequencing and identification with precision mass spectrometry. Journal of proteome Research, 6(1), 114-123. https://doi.org/10.1021/pr060271u
Samgina, T. Y., Artemenko, K. A., Gorshkov, V. A., Lebedev, A. T., Nielsen, M. L., Savitski, M. M. & Zubarevand, R. A. (2007). Electrospray ionization tandem mass spectrometry sequencing of novel skin peptides from Ranid frogs containing disulfide bridges. European Journal of Mass Spectrometry, 13(2), 155-163. https://doi.org/10.1255/ejms.867
Savitski, M. M., Kjeldsen, F., Nielsen, M. L. & Zubarev, R. A. (2007). Hydrogen Rearrangement to and from Radical z Fragments in Electron Capture Dissociation of Peptides. Journal of The American Society for Mass Spectrometry, 18(1), 113-120. https://doi.org/10.1016/j.jasms.2006.09.008
Savitski, M. M., Kjeldsen, F., Nielsen, M. L. & Zubarev, R. A. (2007). Relative specificities of water and ammonia losses from backbone fragments in collision-activated dissociation. Journal of proteome Research, 6(7), 2669-2673. https://doi.org/10.1021/pr070121z
Savitski, M. M., Nielsen, M. L. & Zubarev, R. A. (2007). Side-chain losses in electron capture dissociation to improve peptide identification. Analytical Chemistry, 79(6), 2296-2302. https://doi.org/10.1021/ac0619332
Fälth, M., Savitski, M. M., Nielsen, M. L., Kjeldsen, F., Andren, P. E. & Zubarev, R. A. (2007). SwedCAD, a database of annotated high-mass accuracy MS/MS spectra of tryptic peptides. Journal of proteome Research, 6(10), 4063-4067. https://doi.org/10.1021/pr070345h
Nielsen, M. L., Savitski, M. M. & Zubarev, R. A. (2005). Improving protein identification using complementary fragmentation techniques in fourier transform mass spectrometry. Molecular and Cellular Proteomics, 4(6), 835-845. https://doi.org/10.1074/mcp.T400022-MCP200
Nielsen, M. L., Savitski, M. M., Kjeldsen, F. & Zubarev, R. A. (2004). Physicochemical properties determining the detection probability of tryptic peptides in fourier transform mass spectrometry. A correlation study. Analytical Chemistry, 76(19), 5872-5877. https://doi.org/10.1021/ac049571q
Rappsilber, J., Moniatte, M., Nielsen, M. L., Podtelejnikov, A. V. & Mann, M. (2003). Experiences and perspectives of MALDI MS and MS/MS in proteomic research. International Journal of Mass Spectrometry, 226(1), 223-237. https://doi.org/10.1016/S1387-3806(02)00976-4
Haselmann, K. F., Budnik, B. A., Kjeldsen, F., Nielsen, M. L., Olsen, J. V. & Zubarev, R. A. (2002). Electronic excitation gives informative fragmentation of polypeptide cations and anions. European Journal of Mass Spectrometry, 8(2), 117-121. https://doi.org/10.1255/ejms.479
Olsen, J. V., Kristensen, D. B., Nielsen, M. L., Wisniewski, J. R., Jespersen, G., Ong, S. E. & Mann, M. (2002). Mass difference scanning of isotopically labeled peptides for protein quantification by LC-MS/MS. 273-274. Afhandling præsenteret på Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics, Orlando, FL, USA.
Nielsen, M. L., Bennett, K. L., Larsen, B., Moniatte, M. & Mann, M. (2002). Peptide end sequencing by orthogonal MALDI tandem mass spectrometry. Journal of proteome Research, 1(1), 63-71. https://doi.org/10.1021/pr0155174
Nielsen, M. L., Bennett, K. L., Larsen, B., Wisniewski, J. R., Podtelejnikov, A. & Mann, M. (2002). Quantitation and end sequencing of 18O labelled peptides by orthogonal MALDI tandem mass spectrometry. 327-328. Afhandling præsenteret på Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics, Orlando, FL, USA.
Olsen, J. V., Haselmann, K. F., Nielsen, M. L., Budnik, B. A., Nielsen, P. E. & Zubarev, R. A. (2001). Comparison of electron capture dissociation and collisionally activated dissociation of polycations of peptide nucleic acids. Rapid Communications in Mass Spectrometry, 15(12), 969-974. https://doi.org/10.1002/rcm.317
Zubarev, R. A., Nielsen, M. L. & Budnik, B. A. (2000). Tandem ionization mass spectrometry of biomolecules. European Journal of Mass Spectrometry, 6(3), 235-240. https://doi.org/10.1255/ejms.351

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Revideret 11.05.2026
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Helene Eriksen