Publications

10 selected publications from the last ten years:

1. Jonas D. Elsborg, Sebastian H. N. Munk, Zita Fábian, Alba Adelantado-Rubio, Victor Imburchia, Ivo A. Hendriks, Sara C. Larsen, Jiri Bartek, Sébastien Huet, Julien P. Duxin, Apolinar Maya- Mendoza, Michael L. Nielsen. “PARP1 auto-modification promotes faithful Okazaki fragment processing and limits replication fork speed” Molecular Cell, 2025, Online October 2nd

2. Alexandra K.L.F.S. Rebak, Sara C. Buch-Larsen, Ivo A. Hendriks, Jonas D. Elsborg, Rebecca Kirsch, Nadezhda Tsankova Doncheva, Lars Juhl Jensen, Maria Christophorou and Michael L. Nielsen. “A quantitative and site-specific atlas of the citrullinome reveals widespread existence of citrullination and insights into PADI4 substrates”, Nature Structural & Molecular Biology, 2024

3. Meeli Mullari, Nicolas Fossat, Niels H. Skotte, Andrea Asenjo-Martinez, David T. Humphreys, Jens Buhk, Agnete Kirkeby, Troels K. H. Scheel, and Michael L. Nielsen. “The RNA-binding protein atlas of the mammalian brain uncovers a role for RBM5 in Huntington’s disease”, Nature Communication, 2023,

4. Massimo Carraro, Ivo A Hendriks, Colin M. Hammond, Victor Solis, Moritz Völker-Albert, Jonas D Elsborg, Melanie Weisser, Christos Spanos, Guillermo Motoya, Juri Rappsilber, Axel Imhof, Michael L. Nielsen*, Anja Groth*, “Mapping the histone chaperone network unveils DAXX-mediated heterochromatin assembly”, Molecular Cell, 2023 *Shared correspondence

5. Camilla S. Colding-Christensen, Ellen S. Kakulidis, Javier A. Gomez, Ivo A. Hendriks, Connor Arkinson, Agnieszka Gambus, Niels Mailand, Julien P. Duxin, Michael L. Nielsen. “Profiling ubiquitin signaling with UBIMAX reveals DNA damage- and SCFβTRCP-dependent ubiquitylation of the actin-organizing protein Dbn1”, Nature Communications, 2023

6. Ivo A. Hendriks, Sara C. Buch-Larsen, Evgeniia Prokhorova, Alexandra K.L.F.S. Rebak, Ivan Ahel & Michael L. Nielsen,. “The regulatory landscape of the human HPF1- and ARH3-dependent ADP- ribosylome”, Nature Communications, 2021

7. Ivo A. Hendriks, David Lyon, Dan Su, Jeremy A. Daniel, Lars J. Jensen and Michael L. Nielsen. ”Site-specific characterization of endogenous SUMOylation across species and organs”, Nature Communications, 2018

8. Ivo A. Hendriks, David Lyon, Clifford Young, Lars J. Jensen, Alfred C.O. Vertegaal and Michael L. Nielsen.” Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation”, Nature Structural & Molecular Biology, 2017

9. Sara C. Larsen, Kathrine B. Sylvestersen, Andres Mund, Maria V. Madsen, David Lyon, Jeremy A. Daniel, Lars Juhl-Jensen, and Michael L. Nielsen, “Proteome-wide analysis of arginine mono-methylation reveals wide-spread occurrence in human cells”, Science Signaling, 2016

10. Rita Martello, Mario Leutert, Stephanie Jungmichel, Vera Bilan, Sara C. Larsen, Clifford Young, Michael O. Hottiger and Michael L. Nielsen,“Proteome-wide identification of the endogenous ADP-ribosylome of mammalian cells and tissue”, Nature Communications, 2016

Peer-reviewed articles

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Danielsen, J. M. R., Sylvestersen, K. B., Bekker-Jensen, S., Szklarczyk, D., Poulsen, J. W., Horn, H., Jensen, L. J., Mailand, N. & Nielsen, M. L. (2011). Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. Molecular and Cellular Proteomics, 10(3). https://doi.org/10.1074/mcp.M110.003590

Vesterlund, M., Zadjali, F., Persson, T., Nielsen, M. L., Kessler, B. M., Norstedt, G. & Flores-Morales, A. (2011). The SOCS2 ubiquitin ligase complex regulates growth hormone receptor levels. PLoS One, 6(9), Article e25358. https://doi.org/10.1371/journal.pone.0025358

Choudhary, C., Kumar, C., Gnad, F., Nielsen, M. L., Rehman, M., Walther, T. C., Olsen, J. V. & Mann, M. (2009). Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science, 325(5942), 834-840. https://doi.org/10.1126/science.1175371

Fäith, M., Savitski, M. M., Nielsen, M. L., Kjeldsen, F., Andren, P. E. & Zubarev, R. A. (2008). Analytical utility of small neutral losses from reduced species in electron capture dissociation studied using SwedECD database. Analytical Chemistry, 80(21), 8089-8094. https://doi.org/10.1021/ac800944u

De Godoy, L. M. F., Olsen, J. V., Cox, J., Nielsen, M. L., Hubner, N. C., Fröhlich, F., Walther, T. C. & Mann, M. (2008). Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast. Nature, 455(7217), 1251-1254. https://doi.org/10.1038/nature07341

Displaying results 61 to 65 out of 81

[Translate to English:] Selected publications

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Revised 23.04.2026