Institut for Molekylærbiologi og Genetik

Aarhus Universitets segl
Du er her: Institut for Molekylærbiologi og Genetik Forskning Forskningscentre CellPAT Research STEFFEN THIEL: Innate Immune system

STEFFEN THIEL: Innate Immune system

Steffen Thiel’s research focus is the processes that create inflammation in the body and his group is among the leaders in the field of immune recognition.

Steffen Thiel has been deeply involved in the description of the proteins and processes in the part of the immune system referred to as the complement system.

Recent publications

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Dahl, M. R., Thiel, S., Matsushita, M., Fujita, T., Willis, A. C., Christensen, T., Vorup-Jensen, T. & Jensenius, J. C. (2001). MASP-3 and its association with distinct complexes of the mannan-binding lectin complement activation pathway. Immunity, 15, 127-135.
Vorup-Jensen, T., Sørensen, E. S., Jensen, U. B., Schwaeble, W., Kawasaki, T., Ma, Y., Uemura, K., Wakamiya, N., Suzuki, Y., Jensen, T. G., Takahashi, K., Ezekowitz, R. A., Thiel, S. & Jensenius, J. C. (2001). Recombinant expression of human mannan-binding lectin. International Immunopharmacology, 1(4), 677-87.
Celik, I., Stover, C., Botto, M., Thiel, S., Tzima, S., Kunkel, D., Walport, M., Lorenz, W. & Schwaeble, W. (2001). Role of the classical pathway of complement activation in experimentally induced polymicrobial peritonitis. Infection and Immunity, 69, 7304-7309.
Vorup-Jensen, T., Jensen, U. B., Liu, H., Kawasaki, T., Uemura, K., Thiel, S., Dagnaes-Hansen, F. & Jensen, T. G. (2001). Tail-vein injection of mannan-binding lectin DNA leads to high expression levels of multimeric protein in liver. Molecular Therapy, 3(6), 867-74. https://doi.org/10.1006/mthe.2001.0335
Stover, C., Endo, Y., Takahashi, M., Lynch, N. J., Constantinescu, C., Vorup-Jensen, T., Thiel, S., Friedl, H., Hankeln, T., Hall, R., Gregory, S., Fujita, T. & Schwaeble, W. (2001). The human gene for mannan-binding lectin-associated serine protease-2 (MASP-2), the effector component of the lectin route of complement activation, is part of a tightly linked gene cluster on chromosome1p36.2-3. Genes and Immunity, 2, 119-127.

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Full list of publications

Group leader

Revideret 30.07.2026
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Viktor Hauge Ladegaard