Institut for Molekylærbiologi og Genetik

Aarhus Universitets segl
Du er her: Institut for Molekylærbiologi og Genetik Forskning Forskningscentre CellPAT Research STEFFEN THIEL: Innate Immune system

STEFFEN THIEL: Innate Immune system

Steffen Thiel’s research focus is the processes that create inflammation in the body and his group is among the leaders in the field of immune recognition.

Steffen Thiel has been deeply involved in the description of the proteins and processes in the part of the immune system referred to as the complement system.

Recent publications

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Kjaer, T. R., Le, L. T. M., Pedersen, J. S., Sander, B., Golas, M. M., Jensenius, J. C., Andersen, G. R. & Thiel, S. (2015). Structural Insights into the Initiating Complex of the Lectin Pathway of Complement Activation. Structure, 23(2), 342-351. https://doi.org/10.1016/j.str.2014.10.024
Osthoff, M., Wojtowicz, A., Tissot, F., Jørgensen, C., Thiel, S., Zimmerli, S., Marchetti, O., Khanna, N., Bochud, P.-Y., Trendelenburg, M. & Fungal Infection Network of Switzerland (FUNGINOS) (2016). Association of lectin pathway proteins with intra-abdominal Candida infection in high-risk surgical intensive-care unit patients. A prospective cohort study within the fungal infection network of Switzerland. Journal of Infection, 72(3), 377-385. https://doi.org/10.1016/j.jinf.2015.12.011
Banda, N. K., Acharya, S., Scheinman, R. I., Mehta, G., Takahashi, M., Thiel, S., Sekine, H., Fujita, T. & Holers, V. M. (2016). Complement mannan-binding lectin associated serine proteases 1 and 3 generated by allo-liver transplantation cleave in vivo pro-Factor D generated by the adipose tissue into active Factor D. Journal of Immunology, 196(1 Supplement).
Østergaard, J. A., Ruseva, M. M., Malik, T. H., Hoffmann-Petersen, I. T., Pickering, M. C., Thiel, S. & Hansen, T. K. (2016). Increased Autoreactivity of the Complement-Activating Molecule Mannan-Binding Lectin in a Type 1 Diabetes Model. Journal of Diabetes Research, 2016, 1825738. Artikel 1825738. https://doi.org/10.1155/2016/1825738
Bro-Jeppesen, J., Kjaergaard, J., Thiel, S., Jensenius, J. C., Bjerre, M., Wanscher, M., Christensen, J. V. & Hassager, C. (2016). Influence of mannan-binding lectin and MAp44 on outcome in comatose survivors of out-of-hospital cardiac arrest. Resuscitation, 101, 27-34. https://doi.org/10.1016/j.resuscitation.2016.01.007

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Full list of publications

Group leader

Revideret 30.07.2026
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Viktor Hauge Ladegaard